Download or read book Monitoring and Evaluation of Biomaterials and their Performance In Vivo written by Roger Narayan and published by Woodhead Publishing. This book was released on 2016-11-11 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monitoring and Evaluation of Biomaterials and Their Performance In Vivo provides essential information for scientists and researchers who need to assess and evaluate performance, monitor biological responses, gauge efficacy, and observe changes over time. Crucially, it also enables the optimization of design for future biomaterials and implants. This book presents readers with comprehensive coverage of the topic of in vivo monitoring of medical implants and biomaterials. - Contains a specific focus on monitoring and evaluation of biomaterials in vivo - Multi-faceted coverage of materials function and performance - Focuses on a range of implants and subsequent bodily reactions
Download or read book Handbook Of Biomaterials Evaluation written by Andreas F von Recum and published by CRC Press. This book was released on 1998-12-18 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook addresses the needs of those who are involved in inventing, developing, and testing implants and are concerned about the interactions between biomaterial and body tissue. The authors explore the physical, chemical, mechanical and regulatory considerations of synthetic materials used in surgical and implant procedures, and how these factors impact the latest developments and new approaches. This updated edition provides the biomaterials professional with necessary information on a range of issues, including bulk characterization, surface evaluations, toxicological evaluations, in vitro methods for safety evaluation, methods for evaluating materials in special applications, surgical considerations, systems implantology, soft and hard tissue history, regulatory aspects, and clinical trials.
Download or read book Biocompatibility and Performance of Medical Devices written by Jean-Pierre Boutrand and published by Woodhead Publishing. This book was released on 2019-11-21 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biocompatibility and Performance of Medical Devices, Second Edition, provides an understanding of the biocompatibility and performance tests for ensuring that biomaterials and medical devices are safe and will perform as expected in the biological environment. Sections cover key concepts and challenges faced in relation to biocompatibility in medical devices, discuss the evaluation and characterization of biocompatibility in medical devices, describe preclinical performance studies for bone, dental and soft tissue implants, and provide information on the regulation of medical devices in the European Union, Japan and China. The book concludes with a review of histopathology principles for biocompatibility and performance studies. - Presents diverse insights from experts in government, industry and academia - Delivers a comprehensive overview of testing and interpreting medical device performance - Expanded to include new information, including sections on managing extractables, accelerating and simplifying medical device development through screening and alternative biocompatibility methods, and quality strategies which fasten device access to market
Download or read book Evaluation of Biomaterials written by European Conference on Biomaterials. 1, 1977, Strasbourg and published by . This book was released on 1980 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomedical Product and Materials Evaluation written by P.V. Mohanan and published by Woodhead Publishing. This book was released on 2022-01-22 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Product and Materials Evaluation: Standards and Ethics provides a much-needed overview of the procedures, issues, standards and ethical issues in the early development of biomedical products. The book covers a range of key biomedical products, from 3D printed organs and blood derived products, to stem calls and decellularized tissue products. Each chapter reviews a single product type, associated materials, biomedical applications, proven development strategies, and potential challenges. The core focus of the book is on the standardization and ethical aspects of biomedical product development, with these elements addressed and discussed in chapters dedicated to product evaluation. This is a useful reference for academics, researchers and industry professionals in R&D groups with an interest in biomaterial research and production, as well as those working in the fields of biomedical engineering, biotechnology and toxicology. - Covers a variety of biomedical products, including specific biomaterials, organs-on-chips, wound care products, combinational products, and more - Delves into strategies and considerations for product evaluation, including cytotoxicity assays, microbial and blood compatibility studies - Discusses standardization and ethical hurdles in biomedical product development and how to overcome them
Download or read book Biomaterials Medical Devices and Combination Products written by Shayne Cox Gad and published by CRC Press. This book was released on 2015-12-01 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials, Medical Devices, and Combination Products is a single-volume guide for those responsible for-or concerned with-developing and ensuring patient safety in the use and manufacture of medical devices.The book provides a clear presentation of the global regulatory requirements and challenges in evaluating the biocompatibility and clinical
Download or read book Evaluation of Biomaterials written by European Conference on Biomaterials Staff and published by . This book was released on with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomaterials for Skin Repair and Regeneration written by Elena Garcia-Gareta and published by Woodhead Publishing. This book was released on 2019-06-05 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials for Skin Repair and Regeneration examines a range of materials and technologies used for regenerating or repairing skin. With a strong focus on biomaterials and scaffolds, the book also examines the testing and evaluation pathway for human clinical trials. Beginning by introducing the fundamentals on skin tissue, the book goes on to describe contemporary technology used in skin repair as well as currently available biomaterials suitable for skin tissue repair and regeneration. Skin tissue engineering and the ideal requirements to take into account when developing skin biomaterials are discussed, followed by information on the individual materials used for skin repair and regeneration. As evaluation of biomaterials in animal models is mandatory before proceeding into human clinical trials, the book also examines the different animal models available. With a strong focus on materials, engineering, and application, this book is a valuable resource for materials scientists, skin biologists, and bioengineers with an interest in tissue engineering, regeneration, and repair of skin. - Provides an understanding of basic skin biology - Comprehensively examines a variety of biomaterial approaches - Looks at animal models for the evaluation of biomaterial-based skin constructs
Download or read book Test Procedures for the Blood Compatibility of Biomaterials written by S. Dawids and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the first European effort to provide a collection of test descriptions used in evaluation of the compatibility of biomaterials in contact with tissues and blood. The urge to compile this book arose from the fact that it is the properties of the material which ultimatively seem to determine the functional outcome of a medical device, almost regardless of how ingenious the construction of the very device is. The longer the exposure is, the more important these basic properties become. Unfortunately only a small part of the interactive phenomena is fully elucidated and understood. This challenge reflects itself in an effort to cover numerous aspects of testing, beginning with fundamental analysis of the material, continuing with the mechanical properties, the resistance to degradation and the analysis of surface and chemical properties including adsorption patterns of proteins ending with test on cell cultures, ex vivo and in vivo. A number of the tests which are generally accepted as being important are already described as official requirements (primarily Pharmacopeas). These official requirements are not included in order to limit the size of the book. It is the aim of this book to present the tests like a recipe in a uniform way to ease the reader in finding his/her way through the material and to present it as a kind of "cook-book" in an order to provide an easy access to copy the procedures. This has unfortunately not been possible in all circumstances.
Download or read book Dental Biomaterials written by R V Curtis and published by Elsevier. This book was released on 2014-01-23 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dental Biomaterials: Imaging, Testing and Modelling reviews the materials used in this important area, their performance and how such performance can be measured and optimised. Chapters review optical and electron microscopy imaging techniques for dental biomaterial interfaces. Specific materials such as dental cements, fibre-reinforced composites, metals and alloys are discussed. There is an analysis of stresses, fracture, wear and ageing in dental biomaterials as well as an evaluation of the performance of dental adhesives and resin-dentin bonds. Chapters also review ways of assessing the performance of dental handpieces, crowns, implants and prosthesies. The book also reviews the use of computer models in such areas as bond strength and shape optimisation of dental restorations.With its distinguished editors and team of experienced contributors DDental Biomaterials: Imaging, Testing and Modelling researchers, materials scientists, engineers and dental practitioners with an essential guide to the use and performance of dental biomaterials. - An essential guide to the use and performance of dental biomaterials - Reviews optical and electron microscopy imaging techniques for dental biomaterial interfaces - Analyses stresses, fracture, wear and ageing in dental biomaterials and evaluates the performance of dental adhesives and resin-dentin bonds
Download or read book Cell Culture Technology written by Cornelia Kasper and published by Springer. This book was released on 2018-10-10 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an overview on current cell culture techniques, conditions, and applications specifically focusing on human cell culture. This book is based on lectures, seminars and practical courses in stem cells, tissue engineering, regenerative medicine and 3D cell culture held at the University of Natural Resources and Life Sciences Vienna BOKU and the Gottfried Wilhelm Leibniz University Hannover, complemented by contributions from international experts, and therefore delivers in a compact and clear way important theoretical, as well as practical knowledge to advanced graduate students on cell culture techniques and the current status of research. The book is written for Master students and PhD candidates in biotechnology, tissue engineering and biomedicine working with mammalian, and specifically human cells. It will be of interest to doctoral colleges, Master- and PhD programs teaching courses in this area of research.
Download or read book Characterization of Biomaterials written by Susmita Bose and published by Elsevier Inc. Chapters. This book was released on 2013-03-12 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief introductory chapter provides a broad overview of materials, biomaterials and the need to understand different techniques to characterize biomaterials. From this chapter, the reader can gain a perspective on how the rest of the topics in different chapters are divided to fully comprehend this inherently multidisciplinary field. Application of appropriate characterization tools can not only save time to fully evaluate different biomaterials, it can also make commercial biomedical devices safer. In the long run, safer biomedical devices can only reduce the pain and suffering of mankind, a dream that resonates with every biomedical researcher.
Download or read book The Williams Dictionary of Biomaterials written by and published by Liverpool University Press. This book was released on 1999-01-01 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a rapid expansion of activity in the area of biomaterials and related medical devices, both in scientific terms and in clinical and commercial applications. The definition of terms has failed to keep pace with the rapidity of these developments and there is considerable confusion over the terminology used in this highly multi- and inter-disciplinary area. This confusion has arisen partly from the use of inappropriate terms which already have well-defined meanings in their parent disciplines, but which are used inexpertly by those working in other disciplines, and partly from the haphazard generation of new terms for the purpose of defining new phenomena or devices. For example, many terms used in pathology with distinct, if not readily understood, meanings are used by materials scientists to describe biocompatibility phenomena with slightly changed or even wholly misrepresented meanings; similarly, terms from materials science and engineering are seriously misused by biologists and clinicians working in this field. The leading proponent of harmonization and clarity in medical device terminology, Professor D. F. Williams has been influential in setting the standard for the accurate definition of some of the terms used. In particular, the definition of biocompatibility, ‘the Williams definition’, agreed at a 1987 conference has been adopted worldwide. Now, in association with O’Donnell and Associates of Brussels, he has prepared The Williams Dictionary to provide a definitive exposition of the meaning of the terminology used in the area of biomaterials and medical devices. It includes definitions and explanations of more than 2,000 terms from many areas, including biomaterials and medical devices, materials science, biological sciences, and clinical medicine and surgery.
Download or read book Biomaterials Science written by Buddy D. Ratner and published by Elsevier. This book was released on 2004-08-18 with total page 879 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials. - Provides comprehensive coverage of principles and applications of all classes of biomaterials - Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics - Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field - Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites - Endorsed by the Society for Biomaterials
Download or read book Biomaterials for Musculoskeletal Regeneration written by Bikramjit Basu and published by Springer. This book was released on 2016-11-01 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the basics of the biomaterials science its applications to bone tissue engineering. The introductory section describes the most necessary concepts and techniques related to the cell and molecular biology with a particular focus on evaluating the biocompatibility property. The layout of this book facilitates easier understanding of the area of bone tissue engineering. The book integrates the Materials Science and Biological Science. It covers processing and basic material properties of various biocompatible metals and ceramics-based materials, in vitro and in vivo biocompatibility and toxicity assessment in the context of bone tissue engineering, and processing and properties of metal-, ceramic- and polymer-based biocomposites, including the fabrication of porous scaffold materials. The book can be used as a textbook for senior undergraduate and graduate coursework. It will also be a useful reference for researchers and professionals working in the area.
Download or read book Handbook of Biomaterial Properties written by William Murphy and published by Springer. This book was released on 2016-06-11 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides tabular and text data relating to normal and diseased tissue materials and materials used in medical devices. Comprehensive and practical for students, researchers, engineers, and practicing physicians who use implants, this book considers the materials aspects of both implantable materials and natural tissues and fluids. Examples of materials and topics covered include titanium, elastomers, degradable biomaterials, composites, scaffold materials for tissue engineering, dental implants, sterilization effects on material properties, metallic alloys, and much more. Each chapter author considers the intrinsic and interactive properties of biomaterials, as well as their appropriate applications and historical contexts. Now in an updated second edition, this book also contains two new chapters on the cornea and on vocal folds, as well as updated insights, data, and citations for several chapters.
Download or read book Biomaterials and Implant Biocompatibility written by Anişoara Cîmpean and published by MDPI. This book was released on 2020-03-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific advances in life sciences and engineering are constantly challenging, expanding, and redefining concepts related to the biocompatibility and safety of medical devices. New biomaterials, new products, and new testing regimes are being introduced to scientific research practices. In order to provide clinically predictive results and to ensure a high benefit–risk ratio for patients, we need to optimize material and implant characteristics, and to adapt performance and safety evaluation practices for these innovative medical devices. Various characteristics related to materials and implant development such as raw materials composition, implant surface morphology, design, geometry, porosity, and mechanical properties need to be thoroughly characterized before evaluating the biological performance of implants. Furthermore, with the increase of regulatory demands, biological evaluation needs to ensure appropriate models and methods for each implant development stage. This book is a result of the Special Issue of Materials on "Biomaterials and Implant Biocompatibility”, which focused on the recent progress in development, material testing, and the biocompatibility and bioactivity evaluation of various materials including, but not limited to, bioceramics, biopolymers, biometals, composite materials, biomimetic materials, hybrid biomaterials, and drug/device combinations for implants and prostheses with medical applications spanning from soft to hard tissue regeneration. The book covers aspects ranging from investigations into material characterization to in vitro and in vivo testing for the assessment of biological performance of advanced, novel biomaterials and implants.
