Download or read book Ethnic Differences in Reactions to Drugs and Xenobiotics written by and published by . This book was released on 1986 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ethnic Differences in Reactions to Drugs and Xenobiotics written by and published by . This book was released on 1986 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ethnic Differences in Reactions to Drugs and Xenobiotics written by Werner Kalow and published by . This book was released on 1986 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ethnic Differences in Reactions to Drugs and Xenobiotics written by Werner Kalow and published by . This book was released on 1986 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ethnic Differences in Reactions to Drugs and Xenobotics written by Werner Kalow and published by . This book was released on 1986-06 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Variation in Health and Illness written by Theresa Overfield and published by CRC Press. This book was released on 1995-04-28 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specifically for the health professional, this book contains an extensive compilation of research findings on biologic variation by race, age, and gender relating to health and illness. Completely rewritten, revised, and updated, the Second Edition includes an increased discussion of biologic variation and expanded coverage of each chapter topic. This book provides a theoretical framework for understanding the mechanisms that influence biologic variation. It presents a well-documented discussion of research data and indicates areas where knowledge is lacking. A theoretical explanation is followed by examination of surface and anatomical variations, developmental variation, biochemical and enzymatic variations, disease susceptibility differences, and influence of the external variation. Consideration of sexual variation reveals more differences between the sexes than among races. Misconceptions about racial uniformity and diversity are exposed throughout the book. Tables of specific biologic variations allow easy reference and access to the literature.
Download or read book Ethnicity in Drug Development and Therapeutics written by Edyta J. Frackiewicz and published by Cambridge University Press. This book was released on 2011-06-16 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was first published in 2002. It presents an overview of ethnic and racial differences in response to medications and offers insight into the genetic and non-genetic reasons for these differences. The roles of pharmacogenomics and pharmacogenetics in drug development, regulatory aspects of representing minorities in clinical trials, as well as NIH, ICH and FDA guidelines as they pertain to these issues are examined in detail. Finally, various strategies to increase recruitment and retention of minority populations in clinical trials are considered.
Download or read book Interindividual Variability in Human Drug Metabolism written by Gian Maria Pacifici and published by CRC Press. This book was released on 2001-05-24 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an exhaustive, authoritative and updated review on the interindividual variability in drug metabolism in humans. Four chapters address the general background: genetic factors causing variability, interethnic variability, environmental factors and developing and ageing as sources of variability. Six chapters address variability of drug metabolism in vivo: variability of psychotropic drugs, antiepileptic drugs, the dopamine precursor levodopa, cardiovascular active drugs and anti HIV drugs. Seven chapters address the interindividual variability of the main drug metabolizing enzymes: CYP-450s, acetyltransferases, glucuronosyl transferase, methyl transferases, sulfotransferases and glutathione transferases in human liver and extrahepatic tissues. A separate chapter discusses the prediction of drug interaction. Comprehensive in coverage, and with contributions from the leading international experts, this book is essential reading for researchers from both academia and the pharmaceutical industry. Advanced undergraduates and postgraduates in pharmacology, clinical pharmacology, toxicology, biochemistry and epidemiology who are interested in drug metabolism will also find this an indispensable resource.
Download or read book Racial and Ethnic Differences in Disease written by Anthony P. Polednak and published by Oxford University Press, USA. This book was released on 1989 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive account of differences in the frequencies of various diseases among a wide range of racial and ethnic groups throughout the world today. It provides epidemiologists, physicians, sociologists, and anthropologists with a methodological framework for understanding the concepts of race and ethnic group, the use of these concepts in epidemiology, and the interpretation of epidemiologic studies of disease. The volume includes information on the physical anthropology of major racial/ethnic groups, as well as chapters on genetic diseases, infectious and parasitic diseases, cardiovascular diseases, cancers, and many other chronic disorders. Each chapter provides descriptive information on the relative frequencies of diseases and the methods used in studies, as well as a systematic discussion of the interpretation of the racial and ethnic differences described, which may arise from such factors as errors in measurement or socioeconomic differences between groups. Genetic and biological factors are also considered, and many individual studies are summarized and critically appraised. The text is ideal for graduates and undergraduates alike, while the authors non-technical approach is easily accessible to general readers with an interest in the subject.
Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Humana Press. This book was released on 2015-03-17 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.
Download or read book The Relevance of Ethnic Factors in the Clinical Evaluation of Medicines written by S.R. Walker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: For a research-based pharmaceutical company to be successful in the 1990s. it must have a strategic plan for the global development of new chemical entities. Global development can be defined as an attempt to reach all major markets as rapidly as possible and for many companies these will include the United States. Japan. Germany. France. Italy. UK and Canada. which together represent approximately 85% of the pharmaceutical market in the developed world. The mutual acceptance of foreign clinical data would reduce the time and resources required to develop a new medicine for the international market by eliminating the requirement for the routine repetition of clinical studies in local populations. In Japan this has been largely based on the belief that genetic differences in respon siveness may result in a different benefit/risk assessment for a new mediCine. while requests in Europe and the United States for local data relate mainly to methodological and cultural considerations. The importance of this issue has been recognised internationally as it was one of the topics discussed at the International Conference on Harmonisation in Orlando (October 1993) and it is currently on the programme for ICH3 which will be convened in Yokohama in Japan in November 1995.
Download or read book Handbook of Cross Cultural Neuropsychology written by Elaine Fletcher-Janzen and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, relatively few investigations in neuropsychology have been sensitive to the analysis of cultural variables. This handbook will assist the neuropsychologist interested in cultural competence and help increase understanding of the link between cultural competence in assessment and intervention and good treatment outcomes. The handbook authors provide an in-depth discussion of the current status of multicultural training in neuropsychology; specific information on diverse groups (age, gender, ethnicity, etc.), assessment instruments, and clinical populations (HIV infected, seizure disorders, brain injuries); and unique analysis of immigration patterns, forensics, and psychopharmacology. This volume is the first to summarize the cultural data available in neuropsychology. A valuable resource for clinical neuropsychologists, school psychologists and rehabilitation professionals.
Download or read book Psychopharmacology Bulletin written by and published by . This book was released on 1966 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ethnoecology written by Virginia D. Nazarea and published by University of Arizona Press. This book was released on 1999-01-01 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: The re-emerging field of ethnoecology offers a promising way to document and analyze human-environment interactions. Case studies by international experts explore the varied views of scholars on the human dimension of conservation and the different views of local peoples regarding their own environments. Filled with peoples' voices from North and South America, Africa, and Asia, these cases cover a range of issues: natural resource conservation and sustainable development, the relationship between local knowledge and biodiversity, the role of the commons in development, and the importance of diversity and equity in environmental management. Ethnoecology: Situated Knowledge/Located Lives is intended for a wide range of specialists not only in social and natural sciences but also in agricultural studies. It conveys the overriding importance of this powerful methodological approach in providing insiders' perspectives on their environments and how they manage them.
Download or read book Conjugation Reactions In Drug Metabolism written by Gerard J. Mulder and published by CRC Press. This book was released on 1990-02-21 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text investigates the molecular biology of conjugation, and the subsequent activity of the transfered genes "in vivo". Conjugation may be very important when considering biotransformations, as expression of transfered genes may allow organisms to metabolize certain substrates.
Download or read book Pharmacogenomics written by Werner Kalow and published by CRC Press. This book was released on 2001-05-08 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Summarizes the history of, and available applications, techniques, and approaches to, pharmacogenomics--improving efficacy and tolerance to pharmaceutical compounds, evaluating pharmacogenomics on clinical trial design, and increasing the chances of successful clinical trials and patient outcomes. Compares pharmacogenomics to pharmacogenetics, focusing on the essential components that incorporate individual genetic variations to drug regimens resulting in different responses to therapeutics."
Download or read book Assessment of the Use of Single Cytochrome P450 Enzymes in Drug Research written by M.R. Waterman and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic research and especially that which focuses on the monooxygenase cytochrome P450 system has gone through dramatic progressive changes within the last decade. Availability of highly sophisticated analytical techniques has contributed to increased molecular understanding of biotransformation pathways. Nowadays designer drugs are computer composable focussing on metabolic stability. The rapid development of recombinant enzymes has, in many cases, replaced the intensive work on P450 isolation from naturally occurring sources. Recombinant P450s can be expressed in cell lines and thus made available for reproducible and constant use addressig a large number of scientific questions. This book describes the present position of such research.
