Download or read book Ethical Issues in HIV Vaccine Trials written by T. Kerns and published by Springer. This book was released on 1996-12-11 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores some of the complex ethical quandaries entailed by proposed phase III HIV preventive vaccine trials. The book argues that such trials must be initiated as soon as politically and ethically feasible on the one hand, and that no such trials should be undertaken until we can assure full compliance with the Nuremberg Code and the WHO/CIOMS International Ethical Guidelines for Biomedical Research Involving Human Subjects on the other. The tension between these two positions is fully detailed and suggestions offered for how to think about possible resolutions.
Download or read book Adverse reactions to HIV vaccines medical ethical and legal issues written by and published by DIANE Publishing. This book was released on 1995 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: AIDS researchers are investigating new vaccines that would prevent infection with HIV and reduce the spread of AIDS. Some have argued that product liability concerns have discouraged investment in HIV vaccine research and development. The purpose of this OTA background paper is to describe the current state of development of HIV vaccines, and to discuss what is known about adverse reactions that may occur. The background paper provides an overview of ethical issues that arise in the conduct of HIV vaccine trials. The report also discusses alternatives to the current product liability system to encourage the development of HIV vaccines and to fairly compensate those who are harmed as a result of adverse reactions to the vaccine. This background paper was prepared in response to a request from the Subcommittee on Health of the House Ways and Means Committee. It is eleventh in OTA's series of studies on HIV-related issues.
Download or read book The Search for an AIDS Vaccine written by Christine Grady and published by Indiana University Press. This book was released on 1995-05-22 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book is a balanced and comprehensive treatment of an important social issue. It is accessible to the general reader and belongs in public as well as academic libraries." -- Religious Studies Review "Painstaking analysis of the knotty ethical problems involved in human-subjects research, and a well-thought-out proposal for a community approach to conducting field trials for an HIV vaccine.... Highly recommended for medical ethicists and anyone concerned about the AIDS epidemic and how HIV research is conducted."Â -- Kirkus Reviews "... a carefully reasoned account of how research for and trial of a preventive vaccine differ from the methods used to discover a therapy."Â -- Booklist "I highly recommend reading this book which I would attest to be a thrilling, ethically challenging, and informative descent into the allopathic solution." -- Ryan Hosken, Bastyr University Library Newsletter "As the scientific effort to produce an efficacious vaccine continues, [Grady's] work provides an ethical compass that will guide us well, regardless of where phase III HIV vaccine trials ultimately occur." -- Journal of the American Medical Association "Highly recommended... " -- AIDS Book Review Journal "A remarkable treatment of a most difficult and complex subject... Grady's book is of special merit because it is simple, readable, and understandable, while conveying in-depth perceptions that are critical to the reader. A useful and essential reference work for those who would engage in the initiative to bring about a resolution of a mighty human health problem." -- Maurice R. Hilleman, Ph.D., D.Sc., Director, Merck Institute for Therapeutic Research "Dr. Grady's important study captures the complexity of the search for an AIDS vaccine with startling clarity. Her insights into the full range of forces that shape our national response to AIDS vaccine development should read like signposts to vaccinologists, AIDS community activists, and most importantly, the Public Health Service. An impressive contribution." -- Derek Hodel, Gay Men's Health Crisis "This book is recommended to medical ethicists, those involved in non-HIV vaccine trials, and all persons involved in HIV vaccine trials, including investigators, sponsors, study subjects and communities at risk." -- Journal of Health Politics, Policy and Law The creation of a vaccine now seems the best hope for controlling AIDS. Yet developing and testing an HIV vaccine raises a host of difficult ethical issues. These concerns are the focus of this timely and important book. Essential reading for everyone interested in ethics and the conduct of HIV vaccine research.
Download or read book Ethical Issues in HIV Vaccine Trials written by Thomas A. Kerns and published by . This book was released on 1997 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work explores some of the complex ethical quandaries entailed by proposed phase III HIV preventive vaccine trials. It argues that such trials must be initiated as soon as is politically and ethically feasible on the one hand, and, on the other, that no such trials should be undertaken until we can assure full compliance with the Nuremberg Code and the WHO/CIOMS International Ethical Guidelines for Biomedical Research Involving Human Subjects. The tension between these two positions is documented, and suggestions offered for how to think about possible resolutions.
Download or read book Case Studies in Ethics and HIV Research written by Sana Loue and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important work takes as its subject one of medicine’s most pressing arenas of ethical debate. There has been a consistent interest in ethical issues arising in the context of HIV research. Ongoing international and multi-site studies and the continuing search for an HIV vaccine continue to prompt examination of how this research is conducted. Also examined are how participants are engaged in the studies and the obligations of the researchers to individual participants and their communities during the course of and following the conclusion of the research. Each chapter of this book is authored primarily by one of the editors (secondarily by the other) and is accompanied by one to two case studies.
Download or read book Adverse Reactions to HIV Vaccines Medical Ethical and Legal Issues written by and published by . This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: AIDS researchers are investigating new vaccines that would prevent infection with HIV and reduce the spread of AIDS. Some have argued that product liability concerns have discouraged investment in HIV vaccine research and development. The purpose of this OTA background paper is to describe the current state of development of HIV vaccines, and to discuss what is known about adverse reactions that may occur. The background paper provides an overview of ethical issues that arise in the conduct of HIV vaccine trials. The report also discusses alternatives to the current product liability system to encourage the development of HIV vaccines and to fairly compensate those who are harmed as a result of adverse reactions to the vaccine. This background paper was prepared in response to a request from the Subcommittee on Health of the House Ways and Means Committee. It is eleventh in OTA's series of studies on HIV-related issues.
Download or read book Adverse Reactions to HIV Vaccines written by and published by Office of Technology Assessment. This book was released on 1995 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ethical Considerations in HIV Preventive Vaccine Research written by and published by . This book was released on 2000 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document highlights, from UNAID'S perspective, some of the critical elements that must be considered in HIV vaccine development activities.
Download or read book Legal and Ethical Aspects of HIV Related Research written by Emmanuelle E. Wollmann and published by Springer Science & Business Media. This book was released on 2005-11-24 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The motivation and inspiration for this book come directly from expe- ences with clients during the years that I practiced HIV-related law at the Legal Aid Society of San Diego, Inc. The issues discussed in this work reflect issues that arose on a recurring basis with clients participating in HIV research studies, with investigators calling for guidance on the legal implications of particular aspects of their proposed studies, and with research institutions and health care facilities struggling to make sense of legal maneuvers aimed at obtaining the records of their HIV-infected patients. It is impossible to thank each of these persons individually for their provocative questions and their insights. The discussion of ethical and legal issues relating to the design of clinical trials reflects questions raised during discussions with Donald J. Slymen, Ph.D. Don was one of the first researchers, in my realm of experience, to pay close attention to ethical concerns, and I am greatly appreciative of his contribution to both my professional growth and the development of various scenarios discussed in this text. The portions of this text dealing with confidentiality are the result of many hours of thoughtful discussion and analysis with Penn Lerblance, J.D., now deceased and still missed. Penn and I often participated together as presenters of in-service training programs for health prof- sionals. Penn addressed discrimination, and I focused on confidentiality.
Download or read book Ethical and Policy Issues in International Research written by United States. National Bioethics Advisory Commission and published by . This book was released on 2001 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ethics AIDS in Africa written by A. A. Van Niekerk and published by New Africa Books. This book was released on 2005 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Don: American Embassy 2 copies.
Download or read book Ethical Issues in International Biomedical Research written by James V. Lavery and published by . This book was released on 2007 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ethical Issues in International Biomedical Research is the definitive book on the ethics of research involving human subjects in developing countries. Using 21 actual case studies, it covers the most controversial topics, including the ethics of placebo research in Africa, what benefits should be provided to the community after completion of a research trial, how to address conflicts between IRBs in developed and developing countries, and undue inducement of poor people in developing countries. Each case is accompanied by two expert commentaries, written by many of the worlds leading experts in bioethics as well as new voices with research experience in developing countries. No other volume has this scope. Students in bioethics, public and international health, and ethics will find this book particularly useful.
Download or read book Bioethical Challenges in New Hiv Prevention Technologies written by Calvin Gwandure and published by Xlibris Corporation. This book was released on 2018-05-23 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ruth Gwandure earned her master of science degree in medicine (bioethics and law) from the University of the Witwatersrand, South Africa. Her research and consulting fields include bioethics, health law, environmental bioethics, research ethics, HIV and AIDS, ethics and law, clinical ethics, and HIV counselling and testing in schools. Calvin Gwandure has a PhD in psychology. He graduated from Nelson Mandela University, South Africa. His research and consulting fields include HIV and AIDS prevention, new HIV prevention technologies, HIV risk behavior, and group behavior. Clinical trials on HIV and AIDS prevention face challenges associated with infection of participants with HIV and sexually transmitted infections. Participants also experience adverse events associated with voluntary medical male circumcision and the use of microbicides and vaccines in clinical trials. The results obtained from clinical trials investigating the efficacy of microbicides and vaccines in preventing HIV infection are disappointing, but there is hope that one day a breakthrough could be made. Clinical trials on voluntary medical male circumcision and preexposure prophylaxis have shown positive results that warranted approval by the US Food and Drug Administration (FDA) and the World Health Organization (WHO). The major challenge experienced in new HIV prevention clinical trials that are underway and in approved interventions that are being scaled up apparently relates to HIV incidence that threatens the social value and scientific validity of the interventions. Paradoxically, the clinical trials and scale-up interventions have become the new sources of HIV infection although the hypothesized benefit to be realized in the end is conceptualized as outweighing the current risks involved.
Download or read book Jenner on Trial written by Thomas A. Kerns and published by Upa. This book was released on 1997 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines how an Ethics Review Committee using today's ethical standards as articulated in The Nuremburg Code, and the WHO/CIOMS International Ethical Guidelines for Biomedical Research Involving Human Subjects, might assess the scientific and ethical design of Edward Jenner's first experimental vaccine experiment. It explores the potential risks and benefits to young James, the adequacy of the preliminary evidence that Jenner used to justify performing his experiment, and how he might have complied with requirements for informed consent. In addition to its historical interest for 18th century England and for the origins of today's biomedical research ethics standards, the book is significant as a case study in the ethics of basic vaccine research. It thus raises relevant questions about today's vaccine research, particularly HIV vaccine research.
Download or read book Case Studies in Ethics and HIV Research written by Sana Loue and published by Springer. This book was released on 2008-11-01 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important work takes as its subject one of medicine’s most pressing arenas of ethical debate. There has been a consistent interest in ethical issues arising in the context of HIV research. Ongoing international and multi-site studies and the continuing search for an HIV vaccine continue to prompt examination of how this research is conducted. Also examined are how participants are engaged in the studies and the obligations of the researchers to individual participants and their communities during the course of and following the conclusion of the research. Each chapter of this book is authored primarily by one of the editors (secondarily by the other) and is accompanied by one to two case studies.
Download or read book AIDS Society Ethics and Law written by Udo Schüklenk and published by Routledge. This book was released on 2018-12-13 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume features a collection of the most important articles on the social, ethical and legal implications of a variety of problems caused by AIDS. The wide range of articles selected for inclusion were chosen on the basis of three criteria: their theoretical depth and coherence, their impact on the subsequent debate and on the social and ethical relevance of the problems addressed. Sections in the book include: physicians and patients, AIDS and the law, HIV testing, clinical research in developed countries, clinical research in developing countries and dying with dignity
Download or read book Ethical and Policy Issues in International Research Report and recommendations of the National Bioethics Advisory Commission written by United States. National Bioethics Advisory Commission and published by . This book was released on 2001 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
