Download or read book Essais cliniques en imagerie m dicale written by Christophe Chagnaud and published by . This book was released on 1991 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Medical Imaging in Clinical Trials written by Colin G. Miller and published by Springer Science & Business Media. This book was released on 2014-01-30 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few years the use of medical imaging has increased exponentially in routine clinical practice. This has been reflected in a rapidly increasing use of medical imaging in clinical trials, through all phases. More recently this has culminated in a number of inter-disciplinary meetings with the various stake holders, including the FDA. Changes in the regulatory process has resulted, when it comes to the submission of data to the FDA, in a therapeutic agent where one or more of the trial end-points is the assessment of a radiological end-point. No longer is it sufficient to have the images read by the local investigator site. The FDA has also identified Medical Imaging as one of the key 6 points in the Critical Path initiative which was launched in 2004. This puts a keen focus on the role of imaging and the need to clearly identify and understand this aspect of clinical trials. As the pharmaceutical, biotech and medical device industry continues to identify ways to improve and speed up product development, medical imaging plays a more significant role. An understanding of the methodology and the metrics is therefore required but difficult to ascertain in one easy to read volume for individuals entering this field. This book will therefore fulfill this void, be it for the pharmaceutical personnel from medical director to monitor, or the Principal Investigator who is having to understand the complexities of the imaging and why it is having to be sent off-site for a 'central read.'
Download or read book Handbook for Clinical Trials of Imaging and Image Guided Interventions written by Nancy A. Obuchowski and published by John Wiley & Sons. This book was released on 2016-02-15 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference, based on the didactic sessions presented at the annual ‘Clinical Trials Methodology Workshop’ for radiologists, radiation oncologists and imaging scientists (sponsored by the Radiological Society of North America (RSNA)). It focuses on educating radiologists, radiation oncologists and those involved in imaging research with how to design and conduct clinical trials to evaluate imaging technology and imaging biomarkers. The internationally renowned contributors take a broad approach, starting with principles of technology assessment, and then move into specific topics covering the clinical trials of therapy and clinical research in imaging guided interventions including radiotherapy. They discuss the use of imaging as a predictor of therapeutic response, screening trial design, and the practicalities of how to run an efficient clinical trial and good working practices. Later chapters provide a comprehensive array of quantitative methods including: an introduction to statistical considerations in study design, biostatistical analysis methods and their role in clinical imaging research, methods for quantitative imaging biomarker studies, and an introduction to cost effectiveness analysis. Handbook for Clinical Trials of Imaging and Image-Guided Interventions will educate and prepare radiologists at all levels and in all capacities in planning and conducting clinical imaging trials.
Download or read book Les fondamentaux de l imagerie m dicale written by Collège médical français des professeurs and published by Elsevier Health Sciences. This book was released on 2022-10-18 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cet ouvrage transversal du programme de DFGSM 2-3 (diplôme de formation générale en sciences médicales) développe tout au long des 31 chapitres l'ensemble des connaissances fondamentales et des bases techniques de l'imagerie, de la radioanatomie et de la séméiologie élémentaire en imagerie. Ouvrage de référence, en couleurs, il regroupe les notions essentielles qui doivent être connues des étudiants de médecine au terme de ce premier cycle d'études. Cette 2e édition procède à un remaniement complet des chapitres sur l'IRM et sur la reconstruction de l'image. Elle approfondit également le chapitre sur la demande et le compte-rendu des examens d'imagerie, pour répondre aux nouvelles modalités des ECOS (Examens Cliniques Objectifs et Structurés), ou évaluation des compétences, mises en place pour les examens du 2e cycle. Près de 400 illustrations (schémas et clichés d'imagerie) viennent éclairer le texte rédigé avec clarté et concision. L'ensemble de ces illustrations est proposé sur une banque d'images consultable en ligne. Le cours est complété par une rubrique Entraînement proposant une série de QCM pour chaque chapitre. Ces QCM, corrigés en fin d'ouvrage, ont été renouvelés et augmentés pour cette nouvelle édition.
Download or read book Imagerie m dicale written by and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Imaging in Drug Discovery and Early Clinical Trials written by Markus Rudin and published by Birkhäuser. This book was released on 2006-07-11 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph examines the contribution of imaging modalities to the stages of drug discovery and development, from early target validation to their use in clinical development programs. Chapters are devoted to the description of the drug discovery process, to the various imaging modalities preclinically and clinically, to applications of imaging during the optimization of a lead compound, addressing issues such as bioavailability and efficacy, and during drug safety evaluation.
Download or read book CIHR NSERC Medical Imaging Workshop Report written by Judith Bray and published by . This book was released on 2010 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Imagerie m dicale written by Peter Renton and published by Elsevier Masson. This book was released on 2005 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imagerie médicale est un manuel pratique qui s'adresse aux étudiants des premier et deuxième cycles des études médicales et paramédicales. Divisé en cinq parties thématiques (appareils locomoteur, respiratoire, digestif, urogénital et système nerveux central), l'ouvrage répond à un double objectif : enseigner aux étudiants comment demander un examen d'imagerie dans un contexte clinique donné ; apporter une base en sémiologie radiologique. Enfin, une synthèse finale contient les indications et les conseils essentiels à ne pas perdre de vue lors de toute demande d'examen d'imagerie, qui doit toujours répondre à une question clinique et ne saurait précéder ni remplacer l'interrogatoire et l'examen clinique. Rédigé de manière très didactique et concise, ce manuel permettra à l'étudiant de comprendre comment l'imagerie peut gravement aider le clinicien à résoudre un problème, à choisir le meilleur traitement ou à juger de son efficacité.
Download or read book CIHR Three year Implementation Plan and Progress Report written by Canadian Institutes of Health Research and published by . This book was released on 2011 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Superstitious Mind written by Judith Devlin and published by Yale University Press. This book was released on 1987-01-01 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This intriguing book examines popular religion, traditional medicine, witchcraft, apparitions, demonology, and magic in nineteenth-century rural France. Devlin demonstrates that many of the impulses and mental processes now considered superstitious constituted a wholly reasonable response to the pressures of a harsh and impoverished life. Far from the product of a primitive mentality, many of these beliefs have survived in modern culture and can even illuminate the nature of modern mass politics.
Download or read book Qualit de vie li e a l tat de sant crit re d valuation written by Olivier Chassagny and published by Springer Science & Business Media. This book was released on 2002-10-02 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Après plusieurs décennies de recherche, le critère "qualité de vie liée à l'état de santé" est probablement à la croisée des chemins dans le domaine de l'évaluation thérapeutique. Il s'intègre dans le cadre plus large des "Patient-Reported Outcomes". En effet, l'évaluation par le patient lui-même de l'efficacité et de la tolérance des médicaments dans un nombre croissant de pathologies, notamment chroniques, apparaît essentielle. L'introduction précise et justifie les situations et pathologies dans lesquelles la mesure de la qualité de vie apporte une information qui ne peut être mesurée correctement par les critères d'évaluation habituels cliniques, biologiques ou physiologiques. La première partie du livre, rapporte l'état de la science quant à la définition et au développement des questionnaires de qualité de vie et des "Patient-Reported Outcomes". Elle précise les nécessités de l'adaptation culturelle et de la validation psychométrique des questionnaires dans le cadre d'essais cliniques internationaux. Elle rapporte les recommandations pratiques d'un groupe de travail multidisciplinaire (ERIQA, European Regulatory Issues on Quality of Life Assessment) sur la mesure de ces critères dans les essais cliniques. L'application de ces concepts est illustrée dans le domaine de la pathologie rhumatologique, par une revue des questionnaires génériques et spécifiques disponibles. La deuxième partie confronte les arguments des acteurs impliqués dans l'enregistrement du médicament: industriel, et représentants des Agences française et européenne (AFSSAPS, EMEA), et de la FDA américaine. Elle permet de mieux cerner les conditions dans lesquelles les autorités d'enregistrement peuvent accepter les études de qualité de vie. La lecture du livre laisse entrevoir, dès maintenant, une place centrale du patient dans les prises de décision thérapeutique. En dépit de leur approche parfois différente, tous les auteurs du livre emploient un même mot: celui de rigueur (méthodologique, logistique, d'analyse et d'interprétation). C'est à cette exigence que le critère qualité de vie gardera toute sa crédibilité scientifique.
Download or read book Transplantation Rapport D atelier written by Judith Bray and published by . This book was released on 2011 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Annual Report written by Canadian Institutes of Health Research and published by . This book was released on 2009 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book INIS Atomindex written by and published by . This book was released on 1972 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Arr t Du R acteur National de Recherche Universel Et L avenir de la Production D isotopes M dicaux Et de la Recherche Au Canada written by Canada. Parliament. House of Commons. Standing Committee on Natural Resources and published by . This book was released on 2010 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Canadian Journal of Cardiology written by and published by . This book was released on 2008 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:
