Download or read book Environmental Damage to DNA and the Protective Effects of Phytochemicals written by Bechan Sharma and published by CRC Press. This book was released on 2021-08-02 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Damage to DNA and the Protective Effects of Phytochemicals provides information on the toxicity of natural as well as synthetic chemicals in the living systems. These can lead to DNA damage and the emergence of serious consequences or manifestations causing varied health hazards. In addition, the ten chapters of the book reflect on the possible applications of plants or plant extracts to impart protection for living cells from the xenobiotics-mediated DNA damage. The book offers comprehensive coverage of the many essential topics in the subject including: Environmental factors and DNA damage Molecular mechanisms associated with DNA damage by various environmental (Physical, Chemical and Biological) factors Synergistic effects of environmental factors Phytochemicals acting both as DNA protectants and genotoxicants Experimental models for the study of the genotoxic potential of environmental factors and protection by phytochemicals This book connects readers who possess a life sciences background to the current understanding, concept and mechanisms involved in environmental-factors-mediated DNA damage. Scientific terms are introduced, defined, described and placed appropriately in the text. The protective effect of some plant extracts/phytochemicals has also been included. Environmental Damage to DNA and the Protective Effects of Phytochemicals is intended to cater the need of BSc, MSc and research students who are striving to discover the mechanism(s) associated with protection of DNA by plant-based chemicals. This is the first edition of our book and the valuable suggestions and comments from the readers are solicited.

Download or read book Modified Nucleic Acids in Biology and Medicine written by Stefan Jurga and published by Springer. This book was released on 2016-07-29 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is comprised of 18 chapters, covering various aspects of DNA modification and RNA modified bases. It also discusses in detail circular RNA, therapeutic oligonucleotides and their different properties. The chemical nature of DNA, RNA, protein and lipids makes these macromolecules easily modifiable, but they are also susceptible to damage from both endogenous and exogenous agents. Alkylation and oxidation show a potential to disrupt the cellular redox equilibrium and cause cellular damage leading to inflammation and even chronic disease. Furthermore, DNA damage can drive mutagenesis and the resulting DNA sequence changes can induce carcinogenesis and cancer progression. Modified nucleosides can occur as a result of oxidative DNA damage and RNA turnover, and are used as markers for various diseases. To function properly some RNA needs to be chemically modified post-transcriptionally. Dysregulation of the RNA-modification pattern or of the levels of the enzymes that catalyze these modifications alters RNA functionality and can result in complex phenotypes, likely due to defects in protein translation. While modifications are best characterized in noncoding ribonucleic acids like tRNA and rRNA, coding mRNAs have also been found to contain modified nucleosides. This book is a valuable resource, not only for graduate students but also researchers in the fields of molecular medicine and molecular biology.

Download or read book Cruciferous Vegetables Isothiocyanates and Indoles written by International Agency for Research on Cancer and published by IARC. This book was released on 2004 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication sets outs the findings of an IARC Working Group, held in Lyon, France in November 2003, which considered the benefits of a diet rich in cruciferous vegetables in helping to reduce the risk of various cancers. Cruciferous vegetables, such as broccoli, cabbage, cauliflower, watercress and brussel sprouts, contain substantial amounts of compounds which have been shown to inhibit the growth of cancers. This publication reviews current knowledge on the topic, including data from human, experimental and mechanistic studies, as well as making recommendations for future research and public health policy options.

Download or read book Phytochemicals written by Toshiki Asao and published by BoD – Books on Demand. This book was released on 2018-11-07 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.

Download or read book Plant derived Bioactives written by Mallappa Kumara Swamy and published by Springer Nature. This book was released on 2020-05-11 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.

Download or read book An Evidence based Approach to Phytochemicals and Other Dietary Factors written by Jane Higdon and published by Thieme. This book was released on 2012-11-07 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in a completely updated second edition, An Evidence-based Approach to Dietary Phytochemicals and Other Dietary Factors is a trusted resource for all health professionals who need to interpret the explosion of information on the role of a plant-based diet in health and disease. It consolidates a wealth of scientifically accurate, peer-reviewed data on plant foods, dietary phytochemicals, and dietary supplements, and includes information on essential intake recommendations, dietary sources, nutrient and drug interactions, phytochemicals in disease prevention, possible adverse effects, and much more. Special features: All chapters revised and updated, with new sections on choline, coenzyme Q10, L-Carnitine, lipoic acid, and other dietary factors Logically structured for quick access to information: begins with the evidence-based benefits of fruits and vegetables, legumes, nuts, whole grains, coffee, and tea; and goes on to the scientific and clinical data on individual dietary phytochemicals and classes of phytochemicals, including carotenoids, flavonoids, fiber, and more Summaries at the end of each chapter for rapid review Peer-reviewed by experts in the field, ensuring that all material is accurate and up-to-date The well-constructed appendix includes not only a quick reference to diseases and foods and where to find them in the book, but also useful tables on phytochemical-drug interactions, phytochemical-nutrient interactions, and phytochemical-rich foods; a summary of the glycemic index of dietary carbohydrates; and a comprehensive glossary of terms

Download or read book Plant Based Functional Foods and Phytochemicals written by Megh R. Goyal and published by CRC Press. This book was released on 2021-03-30 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant-Based Functional Foods and Phytochemicals: From Traditional Knowledge to Present Innovation covers the importance of the therapeutic health benefits of phytochemicals derived from plants. It discusses the isolation of potential bioactive molecules from plant sources along with their value to human health. It focuses on physical characteristics, uniqueness, uses, distribution, traditional and nutritional importance, bioactivities, and future trends of different plant-based foods and food products. Functional foods, beyond providing basic nutrition, may offer a potentially positive effect on health and cures for various disease conditions, such as metabolic disorders (including diabetes), cancer, and chronic inflammatory reactions. The volume looks at these natural products and their bioactive compounds that are increasingly utilized in preventive and therapeutic medications and in the production of pharmaceutical supplements and as food additives to increase functionality. It also describes the concept of extraction of bioactive molecules from plant sources, both conventional and modern extraction techniques, available sources, biochemistry, structural composition, and potential biological activities.

Download or read book Handbook of Mango Fruit written by Muhammad Siddiq and published by John Wiley & Sons. This book was released on 2017-06-05 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by noted experts in the field, Handbook of Mango Fruit: Production, Postharvest Science, Processing Technology and Nutrition offers a comprehensive resource regarding the production, trade, and consumption of this popular tropical fruit. The authors review the geographic areas where the fruit is grown and harvested, including information on the ever-expanding global marketplace that highlights United States production, imports and exports, and consumption, as well as data on the outlook for the European market. Handbook of Mango Fruit outlines the postharvest handling and packaging techniques and reviews the fruit’s processed products and byproducts that are gleaned from the processing of waste. The authors include information on the nutritional profile of the mango and review the food safety considerations for processing and transport of mangoes. This comprehensive resource: Reviews global mango production trends and countries that are the major exporters and importers of mangoes Explores the burgeoning marketplace for mangoes with special emphasis on the US and European marketplace Assesses latest trends in packaging of and shipping of mangoes Provides in depth coverage on value-added processing and by-products utilization Offers vital information on the innovative processing technologies and nutritional profile of popular tropical fruit Written for anyone involved in the production, marketing, postharvest handling, processing and by-products of mangoes, Handbook of Mango Fruit is a vital resource offering the most current information and guidelines on the burgeoning marketplace as well as the safe handling, production, and distribution of mangoes.

Download or read book Traffic Related Air Pollution written by Haneen Khreis and published by Elsevier. This book was released on 2020-08-20 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traffic-Related Air Pollution synthesizes and maps TRAP and its impact on human health at the individual and population level. The book analyzes mitigating standards and regulations with a focus on cities. It provides the methods and tools for assessing and quantifying the associated road traffic emissions, air pollution, exposure and population-based health impacts, while also illuminating the mechanisms underlying health impacts through clinical and toxicological research. Real-world implications are set alongside policy options, emerging technologies and best practices. Finally, the book recommends ways to influence discourse and policy to better account for the health impacts of TRAP and its societal costs. Overviews existing and emerging tools to assess TRAP’s public health impacts Examines TRAP’s health effects at the population level Explores the latest technologies and policies--alongside their potential effectiveness and adverse consequences--for mitigating TRAP Guides on how methods and tools can leverage teaching, practice and policymaking to ameliorate TRAP and its effects

Download or read book Dietary Phytochemicals written by Chukwuebuka Egbuna and published by Springer Nature. This book was released on 2021-08-20 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents comprehensive coverage on the importance of good nutrition in the treatment and management of obesity, cancer and diabetes. Naturally occurring bioactive compounds are ubiquitous in most dietary plants available to humans and provide opportunities for the management of diseases. The text provides information about the major causes of these diseases and their association with nutrition. The text also covers the role of dietary phytochemicals in drug development and their pathways. Later chapters emphasize novel bioactive compounds as anti-diabetic, anti-cancer and anti-obesity agents and describe their mechanisms to regulate cell metabolism. Written by global team of experts, Dietary Phytochemicals: A Source of Novel Bioactive Compounds for the Treatment of Obesity, Cancer and Diabetes describes the potentials of novel phytochemicals, their sources, and underlying mechanism of action. The chapters were drawn systematically and incorporated sequentially to facilitate proper understanding. This book is intended for nutritionists, physicians, medicinal chemists, drug developers in research and development, postgraduate students and scientists in area of nutrition and life sciences.

Download or read book Photocarcinogenesis Photoprotection written by Ratan Singh Ray and published by Springer. This book was released on 2018-11-30 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the problem of UV-R-induced photocarcinogenesis and its molecular mechanism. It covers different photosensitive xenobiotics (drugs, cosmetics, and environmental pollutants) and their photosensitization mechanisms under ambient UV-R exposure. It also summarizes the role of nanotechnology in skin cancer remedies. It provides a brief overview of the various novel nanocarriers for cosmeceuticals like nanoemulsions, liposomes, solid lipid nanoparticles (SLNs), dendrimers, inorganic nanoparticles, nanocrystals, etc., nanotechnology-based cosmeceutical products which are available in the market. It highlights the possible health hazards caused by nanoparticles on exposure of nano-based cosmetics and describes the recent regulatory rules applied to avoid the nanotoxicity.

Download or read book Oxidative Damage to Nucleic Acids written by Mark D. Evans and published by Springer Science & Business Media. This book was released on 2009-06-11 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides up-to-date coverage of selected topics in nucleic acid oxidation. The topics have been selected to cover everything from basic chemical mechanisms, repair of damage and the biological and pathological meaning of DNA oxidation. The chapters are authored by leading, research active, international experts in the respective topics.

Download or read book Antioxidants Weapons Against Cancer written by Susan Zeppieri and published by Susan Zeppieri . This book was released on 2023-04-15 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antioxidants are remarkable molecules that combat oxidative stress caused by free radicals – unstable molecules that can damage our cells and contribute to the development of various diseases, including cancer. In this insightful eBook, you'll delve into the world of antioxidants, their sources, and how they can help protect our bodies from the insidious reach of cancer. As you navigate through "Antioxidants: Your Allies in the Fight Against Cancer", you will discover: The Basics of Antioxidants: Get acquainted with the nature of antioxidants, their functions, and their various sources in food and supplements. Cancer and Oxidative Stress: Understand how free radicals, oxidative stress, and cellular damage contribute to the development of cancer. The Protective Power of Antioxidants: Learn about the various mechanisms through which antioxidants can help prevent cancer and promote cellular health. Optimizing Antioxidant Intake for Cancer Prevention: Gain practical insights and recommendations for incorporating antioxidant-rich foods and supplements into your daily life to reduce cancer risk.

Download or read book Obesity and the Kidney written by Gunter Wolf and published by Karger Medical and Scientific Publishers. This book was released on 2006 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are currently facing an alarming obesity epidemic, with its well-known health consequences such as metabolic syndrome / type 2 diabetes, cardiovascular diseases, an increased incidence of certain types of cancer, musculoskeletal disorders and pulmonary diseases. Experimental and clinical evidence accumulated in recent years now suggests that obesity has also a major effect on renal structure and function. Since the adipocyte is considered a source of many hormones and cytokines, obesity has much more direct influences on renal function besides mediating hypertension: It can by itself induce renal disease such as focal segmental glomerulosclerosis, but also, more commonly, bring about progression of chronic renal diseases. The present volume is the first comprehensive compilation dedicated to this important topic, featuring discussions of pathophysiological as well as clinical aspects written by the leaders in this emerging field of research. It brings together pathophysiological concepts on how obesity influences renal structure and function, reviews the epidemiology of the problem and provides therapeutic suggestions. This publication is recommended for internists, nephrologists, hypertensiologists, cardiologists, and urologists treating patients with obesity and renal diseases. Furthermore, basic scientists such as renal physiologists, renal pathologists, pharmacologists, biochemists, and epidemiologists who want a comprehensive overview of the topic will also profit from this book.

Download or read book Nutraceutical and Functional Food Components written by Charis M. Galanakis and published by Academic Press. This book was released on 2021-10-24 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutraceutical and Functional Food Components: Effects of Innovative Processing Techniques, Second Edition highlights the impact of recent food industry advances on the nutritional value, functional properties, applications, bioavailability, and bioaccessibility of food components. This second edition also assesses shelf-life, sensory characteristics, and the profile of food products. Covering the most important groups of food components, including lipids, proteins, peptides and amino acids, carbohydrates, dietary fiber, polyphenols, carotenoids, vitamins, aromatic compounds, minerals, glucosinolates, enzymes, this book addresses processing methods for each. Food scientists, technologists, researchers, nutritionists, engineers and chemists, agricultural scientists, other professionals working in the food industry, as well as students studying related fields, will benefit from this updated reference. Focuses on nutritional value, functional properties, applications, bioavailability and bioaccessibility of food components Covers food components by describing the effects of thermal and non-thermal technologies Addresses shelf-life, sensory characteristics and health claims

Download or read book Handbook of Nutrition Diet and Epigenetics written by Vinood B. Patel and published by Springer. This book was released on 2019-02-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode proteins responsible for structural and dynamic components, there is an increasing body of evidence to suggest that nutrition itself may alter the way in which genes are expressed via the process of epigenetics. This is where chemically imposed alteration in the DNA sequence occurs or where the functional expression of DNA is modulated. This may include changes in DNA methylation, non-coding RNA, chromatin, histone acetylation or methylation, and genomic imprinting. Knowledge regarding the number of dietary components that impact on epigenetic processes is increasing almost daily. Marshalling all the information on the complex relationships between diet, nutrition, and epigenetic processes is somewhat difficult due to the wide myriad of material. It is for this reason that the present work has been compiled.

Download or read book Phytochemicals in Health and Disease written by Yongping Bao and published by CRC Press. This book was released on 2004-05-24 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: " well-written and the content is clearly presented. There are plentiful figures and tables, which are effectively labeled and adequately support the content. highly recommended for academic and special libraries. effectively presents current research on phytochemicals in a readable manner." - E-Streams "This landmark volume shows h