Download or read book Engineering Design of a Fission Converter based Epithermal Beam for Neutron Capture Therapy written by Balendra Sutharshan and published by . This book was released on 1998 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sensitivity Studies of the Neutronic Design of a Fission Converter based Ephithermal Beam for Boron Neutron Capture Therapy written by Shuichi Sakamoto and published by . This book was released on 1997 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Frontiers in Neutron Capture Therapy written by M. Frederick Hawthorne and published by Springer. This book was released on 2013-11-11 with total page 1389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Neutron Capture Therapy contains current research results originally presented at the Eighth International Symposium on Neutron Capture Therapy for Cancer in La Jolla, CA. This comprehensive collection of peer-reviewed manuscripts is showcased in two volumes covering all aspects of the development of this multidisciplinary approach to cancer therapy. Volume I of this work includes clinical results and current progress in treatment planning, neutron sources and dosimetry, while Volume II presents the synthesis, pharmacology and tissue-targeting design of boron compounds, including work on preclinical dosimetry and radiobiology. Intended for researchers and clinicians involved with or interested in new modes of cancer therapy, this volume will also serve as a useful guideline for scientists, students, and practitioners in the field.
Download or read book Development and Characterization of an Epithermal Beam for Boron Neutron Capture Therapy at the MITR II Research Reactor written by Jong-Hoi Richard Choi and published by . This book was released on 1991 with total page 901 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cancer Neutron Capture Therapy written by Y. Mishima and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 893 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for example, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was synthesized as Melphalan and used to treat malignant melanoma. A major problem arose though in that it was soon found to be highly suppressive toward bone marrow and quite toxic while not being remarkably effective. Thus, malignant melanoma could not be cured by it. Such failure led us to develop a novel bimodal therapeutic system which includes the use of non-toxic potentially cytocidal chemicals which selectively accumulate within the cancer cells and which are converted by a controllable modality into an actively cytocidal element in situ. We can now non-surgically cure malignant melanoma and glioblastoma with our selective cancer treatment, neutron capture therapy (NCT); as can be found in this volume. Included are 124 papers on the latest breaking developments discussed at the Sixth International Symposium on NCT for Cancer held in Kobe during the late autumn of 1994.
Download or read book Transactions of the American Nuclear Society written by American Nuclear Society and published by . This book was released on 2002 with total page 1096 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development of an epithermal beam for boron neutron capture therapy written by G. Constantine and published by . This book was released on 1984 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Accelerator based Epithermal Photoneutron Source for Boron Neutron Capture Therapy written by Hannah Elizabeth Mitchell and published by . This book was released on 1996 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Neutron Optics written by Maria L. Calvo and published by CRC Press. This book was released on 2019-12-05 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neutron optics studies the interactions of a beam of slow neutrons with matter. This book updates various advances on neutron optics. There will be a focus on the very active topics of neutron imaging (NI) and neutron spin optics (NSO). The book will also present applications of neutron beams in biomedicine, such as Boron Neutron Capture Therapy (BNCT) and related techniques. Features: Discusses diffraction and interference of slow neutrons, including computational approaches Reviews neutron imaging (NI) and neutron spin optics (NSO) Treats two major sources of slow neutron beams: (1) fission reactions at nuclear reactors and (2) collisions in particle accelerators (small ones, spallation sources) of charged particle beams with targets of heavy atoms Selects subjects on fundamental quantum aspects of slow neutrons and on confined propagation and waveguiding thereof Updates slow neutron beams and BNCT
Download or read book Neutron Capture Therapy written by Wolfgang A.G. Sauerwein and published by Springer Science & Business Media. This book was released on 2012-11-05 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter, which in principle allows for tumor cell-selective high-LET particle radiotherapy. This book provides a comprehensive summary of the progress made in NCT in recent years. Individual sections cover all important aspects, including neutron sources, boron chemistry, drugs for NCT, dosimetry, and radiation biology. The use of NCT in a variety of malignancies and also some non-malignant diseases is extensively discussed. NCT is clearly shown to be a promising modality at the threshold of wider clinical application. All of the chapters are written by experienced specialists in language that will be readily understood by all participating disciplines.
Download or read book Design of Neutron Beams at the Argonne Continuous Wave Linac ACWL for Boron Neutron Capture Therapy and Neutron Radiography written by and published by . This book was released on 1994 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neutron beams are designed for capture therapy based on p-Li and p-Sc reactions using the Argonne Continuous Wave Linac (ACWL). The p-Li beam will provide a 2.5 × 109 n/cm2s epithermal flux with 7 × 105 [gamma]/cm2s contamination. On a human brain phantom, this beam allows an advantage depth (AD) of 10 cm, an advantage depth dose rate (ADDR) of 78 cGy/min and an advantage ratio (AR) of 3.2. The p-Sc beam offers 5.9 × 107 n/cm2s and a dose performance of AD = 8 cm and AR = 3.5, suggesting the potential of near-threshold (p, n) reactions such as the p-Li reaction at E{sub p} = 1.92 MeV. A thermal radiography beam could also be obtained from ACWL.
Download or read book American Doctoral Dissertations written by and published by . This book was released on 2001 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Les Bienfaits de la r volution Premier apper u de ce qu elle a co t dater du premier septembre 1789 jusqu au premier mars 1791 written by France and published by . This book was released on 1791 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Optimisation of an Epithermal Beam in HIFAR for Boron Neutron capture Therapy written by B. V. Harrington and published by . This book was released on 1987 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advanced Monte Carlo for Radiation Physics Particle Transport Simulation and Applications written by Andreas Kling and published by Springer. This book was released on 2001-10-02 with total page 1224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the state of the art of Monte Carlo methods in radiation physics and particle transport simulation and applications. Special attention is paid to algorithm development for modeling, and the analysis of experiments and measurements in a variety of fields.
Download or read book Epithermal Beam Development at the BMRR Brookhaven Medical Research Reactor written by and published by . This book was released on 1989 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: The utilization of an epithermal neutron beam for neutron capture therapy (NCT) is desirable because of the increased tissue penetration relative to a thermal neutron beam. Over the past few years, modifications have been and continue to be made at the Brookhaven Medical Research Reactor (BMRR) by changing its filter components to produce an optimal epithermal beam. An optimal epithermal beam should contain a low fast neutron contamination and no thermal neutrons in the incident beam. Recently a new moderator for the epithermal beam has been installed at the epithermal port of the BMRR and has accomplished this task. This new moderator is a combination of alumina (Al2O3) bricks and aluminum (Al) plates. A 0.51 mm thick cadmium (Cd) sheet has reduced the thermal neutron intensity drastically. Furthermore, an 11.5 cm thick bismuth (Bi) plate installed at the port surface has reduced the gamma dose component to negligible levels. Foil activation techniques have been employed by using bare gold and cadmium-covered gold foil to determine thermal as well as epithermal neutron fluence. Fast neutron fluence has been determined by indium foil counting. Fast neutron and gamma dose in soft tissue, free in air, is being determined by the paired ionization chamber technique, using tissue equivalent (TE) and graphite chambers. Thermoluminescent dosimeters (TLD-700) have also been used to determine the gamma dose independently. This paper describes the methods involved in the measurements of the above mentioned parameters. Formulations have been developed and the various corrections involved have been detailed. 12 refs.
