Download or read book Endocrine Dependent Tumors written by Klaus-Dieter Voigt and published by Lippincott Williams & Wilkins. This book was released on 1991 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endocrine Therapies in Breast and Prostate Cancer written by C. Kent Osborne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been recognized for many years that cancers originating in the breast and prostate gland are frequently 'endocrine-dependent. ' Traditional thera pies included surgical endocrine ablative procedures or pharmacologic hor mone administration, both designed to antagonize the stimulatory effects of sex steroid hormones. In the past decade, several new treatment strategies for these tumors have emerged from basic studies in reproductive biology and mechanisms of action of steroid hormones. In some instances, these new treatments have elimin ated or reduced the need for major surgical ablative procedures or for toxic hormone therapy. The clinical role for other new treatments has not yet been clearly defined, although exciting preliminary data from recent clinical trials are now available. Thus, an objective review of the current status of these new therapeutic approaches is of interest. In this volume we have attempted to provide an in-depth review of both basic and clinical research involving several new treatment strategies for breast and prostate cancer. The first three chapters summarize preclinical and clinical studies of the luteinizing hormone-releasing hormone analogues, which can be used effectively to induce 'medical castration. ' Chapters 4, 5, and 6 review the rationale and clinical use of the compounds known collec tively as the aromatase inhibitors, which can also be used to suppress sex steroid hormone levels. Antiestrogen mechanism of action and its clinical implications for the design of innovative treatment approaches is considered in chapters 7 and 8.
Download or read book Endocrine Therapies in Breast and Prostate Cancer written by C Kent Osborne and published by . This book was released on 1988-06-30 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endocrine Dependent Breast Cancer Critical Assessment of Recent Advances written by Eva Juhos and published by . This book was released on 1988 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endocrine dependent Breast Cancer written by Richard J. Santen and published by H. Huber Publishers. This book was released on 1988 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endocrine Therapy of Breast Cancer written by Franco Cavalli and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting in 1986, the European School of Oncology has expanded its activities in postgraduate teaching, which consisted mainly of traditional disease-orientated courses, by promoting new educational initiatives. One of these is the cloister seminars, short meetings intended for highly qualified oncologists and dealing with specific, controversial aspects of clinical practice and research. Another is the institution of permanent study groups, also called task forces, where a limited number of leading experts are invited to meet once a year with the aim of defining the state of the art and possibly reaching a consensus on developments and treatment in specific fields of oncology. This series of ESO Monographs was designed with the specific purpose of disseminating the results of the most interesting of the seminars and study groups, and providing concise and updated reviews of the subjects discussed. It was decided to keep the layout very simple in order to keep costs to a minimum and make the monographs available in the shortest possible time, thus overcoming a common problem in medical literature: that of the material being outdated even before publication. Umberto Veronesi Chairman, Scientific Committee European School of Oncology Table of Contents How to Read this Monograph F.CAvALLI ......... . 1 Experimental Strategies for Studying the Development of Breast Cancer with Special Reference to Steroid Hormones, Growth Factors and Oncogenes R.J.B. KING . . . . . . . . . . . . . . . . . . . . . . . . .. . . . 5 . . .
Download or read book Molecular Endocrinology of Cancer Volume 1 Part 2 Endocrine Therapies written by Jonathan Waxman and published by Cambridge University Press. This book was released on 1996-01-26 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: One third of human cancers have a hormonal basis. Breast cancer, the most common cancer of women, is increasing in incidence in many countries, as, in epidemic proportions, is prostate cancer, the second most common cancer of men. Concurrently, the development of molecular biology has led to a refinement of the definition of hormones to include the complex interaction between tumour cells and both locally and distantly secreted factors. This 1996 volume from the series Cancer: Clinical Science in Practice considers the many aspects of hormonally dependent cancer, including the molecular basis for the autocrine and paracrine regulation of cancer, molecular strategies for cancer detection, preventive strategies in limiting the epidemic of hormonally related cancers, and treatment approaches. The concise volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the application of biomedical science to the understanding and management of cancer.
Download or read book Hormone Therapy in Breast and Prostate Cancer written by JORDAN V. CRAIG and published by Springer Science & Business Media. This book was released on 2010-02-05 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the principles underlying targeted hormonal treatments, assesses the actions of new and established agents, and illustrates the new applications of hormonal chemoprevention for breast cancer.
Download or read book Endocrine induced Regressions of Cancers written by Charles Huggins and published by . This book was released on 1967 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Effects of Various Thyroid States in an Endocrine dependent Breast Tumour in Rats written by Dionisio Ong and published by . This book was released on 1967 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The effects of altered thyroid states have been investigated in a DMBA induced mammary tumor system in Sprague-Dawley rats. Results revealed that both tumor incidence and gross tumor yields were less in the thyroidectomized and 1-thyroxine treated groups, as compared to the intact controls. Furthermore, increasing the dose of 1-thyroxine in the thyroxine treated group, resulted in a reversaI of the progressive tumor growth potential with regression and complete extinction of a significant number of the established mammary tumors in this group. Histologically, tumors of the thyroidectomized and control groups were identical, while a characteristic morphologic variant was seen only in the mammary tumors of the 1-thyroxine treated group. Since the effect was not universally seen throughout the sections examined in any single tumor nodule, it is postulated that tumors are composed of heterogeneous cell populations, one of which is endocrine-dependent or sensitive to the effects of 1-thyroxine administration."--
Download or read book Endocrine Management of Cancer written by Basil Arnold Stoll and published by . This book was released on 1988 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Effects of Throxine on Endocrine Dependent Mammary Tumors in Rats written by Benjamin Mitmaker and published by . This book was released on 1969 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Download or read book Effects of Thyroxine on Endocrine Dependent Mammary Tumors in Rats written by Benjamin Mitmaker and published by . This book was released on 1969 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "The chronic administration of non-toxic doses of thyroxine to rats bearing established mammary tumors resulted in significant regression of tumor growth. Histologically tumor regression resulted from massive cell autolysis, while other cells persisted with the formation of irregular acinar spaces containing a milk-like fiuid histochemically similar to normal rat milk. Electron microscopy revealed structural differentiation in these tumor cells similar to that found in lactating breast cells, but the cellular secretory mechanism and cytomorphological characteristics of this tumor milk were unlike that of a normal lactating rat breast. Furthermore, mammary tumor mitochondria of the thyroxine treated host revealed both structural and functional abnormalities. Although tumor regression occurred despite the endocrine milieu in a hyperthyroid rat favouring tumor growth, it was concluded that thyroid hormone acts directly on the tumor mitochondria to induce a form of wasteful oxidative metabolism, thereby interfering with the energy requirements of the mammary tumor." --
Download or read book Endocrine Tumor Syndromes and Their Genetics written by Constantine A. Stratakis and published by Karger Medical and Scientific Publishers. This book was released on 2013 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: From classic MEN syndromes to various germline and somatic mutations in sporadic tumors In these times, a book should aspire to present the most significant advances in the field, reflect the themes of the moment, and provide a useful compendium for future reference. This book accomplishes all three objectives by discussing the changing world of modern genetics in endocrine tumors and its impact on clinical practice. Clinicians have to incorporate modern genetics and systems biology in their daily practice. Educators and researchers have to introduce molecular pathways and their genetic variability in their teaching, as well as understanding of classic physiology and pathophysiology. Taking these aspects into account, the chapters in this book cover both the classic multiple endocrine neoplasia (MEN) syndromes, as well as newly described ones, such as Carney triad and Carney- Stratakis syndrome. Furthermore, the genetics of paragangliomas as well as thyroid, parathyroid, and pituitary tumors are examined. Outlining the latest research and its obvious implications for our understanding the genetics of endocrine tumor formation and molecular biology of cancer and their potential therapeutic implications, this book is not only useful for researchers but even more so for practicing clinicians, in particular internists, endocrinologists, oncologists, pediatricians, surgeons, pathologists, geneticists, and genetic counselors.
Download or read book Hormone Signaling written by Vincent Goffin and published by Springer Science & Business Media. This book was released on 2002-03-31 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multicellular organisms require a means of intracellular communication to organize and develop the complex body plan that occurs during embryogenesis and then for cell and organ systems to access and respond to an ever changing environmental milieu. Mediators of this constant exchange of information are growth factors, neurotransmmitters, peptide and protein hormones which bind to cell surface receptors and transduce their signals from the extracellular space to the intracellular compartment. Via multiple signaling pathways, receptors of this general class affect growth, development and differentiation. Smaller hydrophobic signaling molecules, such as steroids and non-steroid hormones, vitamins and metabolic mediators interact with a large family of nuclear receptors. These receptors function as transcription factors affecting gene expression, to regulate the multiple aspects of animal and human physiology, including development, reproduction and homeostasis. The aim of this book is to cover various aspects of intracellular signaling involving hormone receptors.
