Download or read book Encyclopedia of Drug Metabolism and Interactions 6 Volume Set written by and published by Wiley. This book was released on 2012-11-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov

Download or read book Encyclopedia of Drug Metabolism and Interactions written by and published by . This book was released on 2012 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This multi-volume encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. The various types of enzymes that can be inhibited or induced and their impact on drug toxicity and altered response are covered both for animal models and humans"--Provided by publisher

Download or read book Encyclopedia of Drug Metabolism and Interactions Clinical Aspects written by and published by Wiley. This book was released on 2012-07-03 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This multi-volume encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. The various types of enzymes that can be inhibited or induced and their impact on drug toxicity and altered response are covered both for animal models and humans"--Provided by publisher.

Download or read book Drug Metabolism and Pharmacokinetics Quick Guide written by Siamak Cyrus Khojasteh and published by Springer Science & Business Media. This book was released on 2011-04-07 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.

Download or read book Encyclopedia of Drug Metabolism and Interactions 6 Volume Set written by and published by Wiley. This book was released on 2012-11-05 with total page 4736 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov

Download or read book Encyclopedia of Drug Metabolism and Interactions 6 Volume Set written by and published by Wiley. This book was released on 2012-11-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov

Download or read book Encyclopedia of Drug Metabolism and Interactions written by and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This multi-volume encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. The various types of enzymes that can be inhibited or induced and their impact on drug toxicity and altered response are covered both for animal models and humans"--Provided by publisher

Download or read book Encyclopedia of Drug Metabolism and Interactions 6 Volume Set written by and published by Wiley. This book was released on 2012-11-05 with total page 4736 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov

Download or read book Encyclopedia of Drug Metabolism and Interactions written by and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This multi-volume encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. The various types of enzymes that can be inhibited or induced and their impact on drug toxicity and altered response are covered both for animal models and humans"--Provided by publisher

Download or read book Metabolic Drug Interactions written by René H. Levy and published by . This book was released on 2000 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together the large body of recent research on metabolic drug interactions and their relevance in the treatment of diseases. The book focuses on human metabolic enzyme systems that have been shown in vitro to be predictive of drug interactions. Major sections present information on specific therapeutic classes of drugs as substrates, inhibitors, and inducers of metabolic enzymes. Other chapters discuss the clinical and pharmacoeconomic implications of metabolic drug interactions and the significance of in vitro metabolic studies in new drug development.

Download or read book Handbook of Drug Metabolism written by Thomas F. Woolf and published by . This book was released on 1999 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the book provides a framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the importance of pharmacokinetics and cytochrome P450, explains clearance, volume of distribution, sequential metabolism, and nonlinear kinetics, summarizes concepts of Phase 1 and 2 metabolites, evaluates tertiary amine metabolism and reactive metabolite chemistry, and more.

Download or read book A Handbook of Bioanalysis and Drug Metabolism written by Gary Evans and published by CRC Press. This book was released on 2019-08-30 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting - until now. A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. These three areas of research help drug developers to optimize the active component within potential drugs thereby increasing their effectiveness, and to provide safety and efficacy information required by regulators when granting a drug license. Professionals with extensive experience in drug discovery and development as well as specialized knowledge of the individual topics contributed to each chapter to create a current and well-credentialed text. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drug-drug interactions. The unique industrial perspective helps to reinforce theory and develop valuable analytical and interpreting skills. This text is an invaluable guide to students in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology, as well as professionals in the biotechnology industry.

Download or read book International Encyclopedia of Pharmacology and Therapeutics written by and published by . This book was released on 1992 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Encyclopedia of Physical Organic Chemistry 6 Volume Set written by Zerong Wang and published by John Wiley & Sons. This book was released on 2017-04-17 with total page 4542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of 2018 PROSE Award for MULTIVOLUME REFERENCE/SCIENCE This encyclopedia offers a comprehensive and easy reference to physical organic chemistry (POC) methodology and techniques. It puts POC, a classical and fundamental discipline of chemistry, into the context of modern and dynamic fields like biochemical processes, materials science, and molecular electronics. Covers basic terms and theories into organic reactions and mechanisms, molecular designs and syntheses, tools and experimental techniques, and applications and future directions Includes coverage of green chemistry and polymerization reactions Reviews different strategies for molecular design and synthesis of functional molecules Discusses computational methods, software packages, and more than 34 kinds of spectroscopies and techniques for studying structures and mechanisms Explores applications in areas from biology to materials science The Encyclopedia of Physical Organic Chemistry has won the 2018 PROSE Award for MULTIVOLUME REFERENCE/SCIENCE. The PROSE Awards recognize the best books, journals and digital content produced by professional and scholarly publishers. Submissions are reviewed by a panel of 18 judges that includes editors, academics, publishers and research librarians who evaluate each work for its contribution to professional and scholarly publishing. You can find out more at: proseawards.com Also available as an online edition for your library, for more details visit Wiley Online Library

Download or read book The ADME Encyclopedia written by Alan Talevi and published by Springer Nature. This book was released on 2022-06-14 with total page 1209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ADME Encyclopedia covers pharmacokinetic phenomena (Absorption, Distribution, Metabolism and Excretion processes) and their relationship with the design of pharmaceutical carriers and the success of drug therapies. It covers both basic and advanced knowledge, serving as introductory material for students of biomedical careers and also as reference, updated material for graduates and professionals working in any field related to pharmaceutical sciences (medicine, pharmaceutical technology, materials science, medicinal chemistry). Structured as alphabetically ordered entries with cross-references, the Encyclopedia not only provides basic knowledge on ADME processes, but also detailed entries on some advanced subjects such as drug transporters, last generation pharmaceutical carriers, pharmacogenomics, personalized medicine, bioequivalence studies, biowaivers, biopharmaceuticals, gene delivery, pharmacometrics, pharmacokinetic drug interactions or in silico and in vitro assessment of ADME properties

Download or read book Encyclopedia of PVC written by Leonard I. Nass and published by CRC Press. This book was released on 1986-02-21 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Volume 1 of this outstanding resource concentrates on safety and environmental concerns in the manufacture and use of resins, and thoroughly discusses theories of degradation, plasticization, solvation, and stabilization. "

Download or read book Drug Metabolism in Drug Design and Development written by Donglu Zhang and published by John Wiley & Sons. This book was released on 2007-11-16 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essentials of drug metabolism vital to developing new therapeutic entities Information on the metabolism and disposition of candidate drugs is a critical part of all aspects of the drug discovery and development process. Drug metabolism, as practiced in the pharmaceutical industry today, is a complex, multidisciplinary field that requires knowledge of sophisticated analytical technologies and expertise in mechanistic and kinetic enzymology, organic reaction mechanism, pharmacokinetic analysis, animal physiology, basic chemical toxicology, preclinical pharmacology, and molecular biology. With chapters contributed by experts in their specific areas, this reference covers: * Basic concepts of drug metabolism * The role of drug metabolism in the pharmaceutical industry * Analytical techniques in drug metabolism * Common experimental approaches and protocols Drug Metabolism in Drug Design and Development emphasizes practical considerations such as the data needed, the experiments and analytical methods typically employed, and the interpretation and application of data. Chapters highlight facts, common protocols, detailed experimental designs, applications, and limitations of techniques. This is a comprehensive, hands-on reference for drug metabolism researchers as well as other professionals involved in pre-clinical drug discovery and development.