Download or read book Encapsulation of Nanoparticles and Polymers Within Block Copolymer Micelles Prepared by the Emulsion and Solvent Evaporation Method written by Gauri M. Nabar and published by . This book was released on 2017 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Additives and external fields Surfactants used during micelle preparation had a surprising effect on the fluorescence of quantum dot loaded micelles. Surfactants that increased the density of the micelle coating around the encapsulated quantum dots enhanced their fluorescence and improved overall stability. External magnetic fields could impact the ordering of magnetic nanoparticles within micelles. This effect was even stronger when the external magnetic field was applied during the encapsulation of magnetic nanoparticles into micelles. Processing conditions Altering the solvent evaporation rate dramatically influenced micelle morphology. Very low rates of solvent evaporation yielded nanoparticle loaded block copolymer nanoparticles with intricate internal geometries. Our studies show that the emulsion and solvent evaporation process is a highly tunable and robust process that can afford access to micelles with interesting morphologies and superior functionality.
Download or read book Nanocarriers for Drug Targeting Brain Tumors written by Lalit Kumar and published by Elsevier. This book was released on 2022-06-21 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems. Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting. - Provides information on the design and development of nanocarriers for targeting brain tumors - Outlines the working principles of different nanocarriers for targeting brain tumors - Includes case studies of different nanocarriers for targeting brain tumors
Download or read book Encapsulation of Nanoparticles in Block Copolymer Micelles and Applications in Biotechnology written by Byeong-Su Kim and published by . This book was released on 2007 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Functional Materials in Biomedical Applications written by Costas Demetzos and published by CRC Press. This book was released on 2023-06-09 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents modern trends that regard the utilization of advanced functional materials for the development of innovative pharmaceuticals. Such materials include classes of lipids, polymers, proteins, and peptides, as well as inorganic materials, which find application in nanomedicinal products, drug delivery systems, medical devices, biotechnological products, and several other technologies. These products are promising for the therapy and diagnosis of diseases. Special attention is given to the available analytical techniques utilized for the evaluation of materials, their interactions, and their properties as well as the functionality of the final pharmaceutical forms. In addition, scale-up opportunities and limitations of nanomaterials and the current and emerging challenges in their clinical translation, with reference to relative regulatory aspects, are discussed. The book covers the latest advances in functional materials for biomedical applications and will serve as a guide for the industry and aid future research. It will be useful for upper undergraduate students and graduate students, young researchers (in the fields of pharmaceutics and materials sciences), scientists who want to enrich their knowledge on advanced drug delivery nanocarriers and their applications, researchers in the Big Pharma and readers who want to learn more about the role of nanoscience in the design and development of nanomedicines.
Download or read book Cancer Theranostics written by Xiaoyuan Chen and published by Academic Press. This book was released on 2014-03-20 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment. Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives. - Supports elimination of multi-step approaches and reduces delays in treatments through combinatorial diagnosis and therapy - Fully assesses cancer theranostics across the emergent field, with discussion of biomarkers, molecular imaging, imaging guided therapy, nanotechnology, and personalized medicine - Content bridges laboratory, clinic, and biotechnology industries to advance biomedical science and improve patient management
Download or read book Polymer and Polymer Hybrid Nanoparticles written by Stanislav Rangelov and published by CRC Press. This book was released on 2013-08-28 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric and hybrid nanoparticles have received increased scientific interest in terms of basic research as well as commercial applications, promising a variety of uses for nanostructures in fields including bionanotechnology and medicine. Condensing the relevant research into a comprehensive reference, Polymer and Polymer-Hybrid Nanoparticles: Fr
Download or read book Nanomedicine written by Yujun Song and published by John Wiley & Sons. This book was released on 2024-11-12 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and multidisciplinary guide to nanomaterials-based medicine Nanomedicine is the study and application of nanomaterials-based medical techniques. In recent years it has very rapidly become indispensable in a huge range of medical contexts, from analysis of extreme life events to diagnosis and treatment of life-threatening intractable diseases, such as cancers and cardiovascular diseases. It has already transformed both research and clinical outcomes in many areas of medicine and promises to continue as the cutting-edge research and clinical area for the next generation of medical specialists. Nanomedicine: Fundamentals, Synthesis, and Applications constitutes a comprehensive guide to this subfield and its recent advances. Beginning with a brief history of the field and introduction to its core principles, it thoroughly treats recent developments in this vital and ever-growing field. Its multidisciplinary approach equips the reader with a systematic overview of these life-saving developments in medicine. Nanomedicine readers will also find: Edited by a leading researcher with decades of experience in both North America and China Detailed treatment of subjects including nanocarriers, nanomaterial bioprobes, multi-function nanodrugs, nanomedicine-mediated immunotherapy and/or physical ablation, and more A comprehensive volume treats every facet of the subject Nanomedicine is a vital resource for biochemists, biomedical engineers, pharmaceutical chemists, physicists, and professionals in the biotechnological industries, as well as for clinicians looking to familiarize themselves with nanomedical techniques and instrumentation.
Download or read book Principles of Biomaterials Encapsulation Volume One written by Farshid Sefat and published by Woodhead Publishing. This book was released on 2022-10-13 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Biomaterials Encapsulation: Volume One, provides an expansive and in-depth resource covering the key principles, biomaterials, strategies and techniques for encapsulation. Volume One begins with an introduction to encapsulation, with subsequent chapters dedicated to a broad range of encapsulation principles and techniques, including spray chilling and cooling, microemulsion, polymerization, extrusion, cell microencapsulation and much more. This book methodically details each technique, assessing the advantages and disadvantages of each, allowing the reader to make an informed decision when using encapsulation in their research. Principles of Biomaterials Encapsulation: Volume One enables readers to learn about the various strategies and techniques available for encapsulation of a wide selection of biomedical substrates, such as drugs, cells, hormones, growth factors and so on. Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, this book offers a deeply interdisciplinary look at encapsulation in translational medicine. As such, this book will provide a useful resource to a broad readership, including those working in the fields of materials science, biomedical engineering, regenerative and translational medicine, pharmacology, chemical engineering and nutritional science. - Details the various biomaterials available for encapsulation, as well as advantages and disadvantages of conventional and contemporary biomaterials for encapsulations - Describes a broad range of applications in regenerative medicine, uniquely bringing encapsulation into the worlds of translational medicine and tissue engineering - Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, offering an interdisciplinary approach
Download or read book Smart Nanocontainers written by Phuong Nguyen Tri and published by Elsevier. This book was released on 2019-11-08 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Nanocontainers explores the fundamental concepts and emerging applications of nanocontainers in biomedicine, pharmaceuticals and smart materials. In pharmaceuticals, nanocontainers have advantages over their micro-counterparts, including more efficient drug detoxification, higher intracellular uptake, better stability, less side effects and higher biocompatibility with tissue and cells. In materials science, such as coating technology, they help by making coatings smarter, stronger and more durable. This important reference will help anyone who wants to learn more on how nanocontainers are used to provide the controlled release of active agents, including their applications in smart coatings, corrosion, drug delivery, diagnosis, agri-food and gas storage. - Discusses how the molecular design of nanocarriers can be optimized to increase performance - Explores how nanocarriers are being used to produce a new generation of active coatings - Explains how nanocarriers are being used to deliver more effective nanoscale drug delivery
Download or read book Design of Nanostructures for Theranostics Applications written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2017-11-30 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry. - Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots - Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders - Assesses the pros and cons of using different nanomaterials for different types of treatment
Download or read book Nanoparticle Therapeutics written by Prashant Kesharwani and published by Academic Press. This book was released on 2021-11-06 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states. This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful. Brings together the novel applications of nanotechnology in biological fields Explores perspectives on technologies through highly organized tables, illustrative figures and flow charts Addresses key multidisciplinary challenges faced by nanotechnologists to foster collaboration among biologists, chemists, physicists, engineers and clinicians
Download or read book Handbook Of Nanobiomedical Research Fundamentals Applications And Recent Developments In 4 Volumes written by Vladimir P Torchilin and published by World Scientific. This book was released on 2014-08-18 with total page 2348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of 4 volumes containing about 70 chapters covering all the major aspects of the growing area of nanomedicine. Leading scientists from 15 countries cover all major areas of nanobiomedical research — materials for nanomedicine, application of nanomedicine in therapy of various diseases, use of nanomedicines for diagnostic purposes, technology of nanomedicines, and new trends in nanobiomedical research.This is the first detailed handbook specifically addressing various aspects of nanobiomedicine. Readers are treated to cutting-edge research and the newest data from leading researchers in this area.
Download or read book Smart Nanomaterials for Bioencapsulation written by Guillermo R. Castro and published by Elsevier. This book was released on 2022-09-30 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Nanomaterials for Bioencapsulation focuses on the fundamentals, synthesis methods and matrix design for the encapsulation of drugs, drug release, food and nutraceuticals, mechanisms of nano- encapsulated drugs on liposomes, micelles, silica composites, carbon nanotubes, dendrimers, and protein inorganic nanohybrids. Providing detailed information on the encapsulation of food and drug derivatives, the book helps create new and modern approaches for both pharmaceutical and nutritional science. The target delivery of pharmacological agents, as well as food additives under various conditions is covered, including sections on systemic release of drug molecules, minimum loss at non-target sites, the accumulation of diseased tissue or organs, and more. Smart nanomaterial-based nanocarriers protect the loaded molecules from premature degradation in the biological environment and enhance bioavailability for cellular uptake. The tuned properties of smart nanomaterials, such as porosity, pore-volume, surface area-to-volume ratio, coating with inert and labile materials, and more help determine the in vivo performance of the bioencapsulated food and drug derivatives. - Outlines the major design principles surrounding the encapsulation of drugs, drug release, food and nutraceuticals at the nanoscale - Discusses the pros and cons of different bioencapsulation methods for different application areas - Outlines the major challenges of applying nanobioencapsulation at an industrial scale
Download or read book Nanoparticles in Life Sciences and Biomedicine written by Ana Rute Neves and published by CRC Press. This book was released on 2018-02-13 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The creation of new and more efficient therapies for improving human health greatly depends on drug delivery systems. Nanotechnology has emerged as a powerful strategy for the development of nanoparticles, such as nanoemulsions, liposomes, nanocrystals, and nanocomplexes, applied in the diagnosis, treatment, or theranostics of several pathologies and diseases. This book reviews the most recent research and development in nanotechnology and, following a multidisciplinary approach, presents new strategies for drug delivery, including aspects from chemistry, physics, biology, and imaging methodologies and exploiting several administration routes, internalization pathways, site-specific delivery strategies, and the potential cytotoxicity of nanoparticles. Beginning with a description of the importance and application of nanotechnology for enhancing existing therapy, the book moves on to detailing oral, topical, pulmonary, brain, cancer, and anti-inflammatory drug delivery approaches; gene delivery approaches; theranostic approaches; and nanoparticle cytotoxicity. Practical and user friendly, it is suitable for advanced undergraduate, graduate, and postgraduate students of nanoscience and nanotechnology; researchers in nanoscience, nanotechnology, chemistry, biology, biochemistry, pharmaceutical sciences, medicine, and bioengineering, especially those with an interest in drug delivery or theranostics; and academia and university readership.
Download or read book Nanocarriers for Drug Delivery written by Josimar O. Eloy and published by Springer Nature. This book was released on 2021 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers basic aspects of different nanoparticles, including type of materials, lipid, polymeric and inorganic structures, synthesis strategies, as well as the main physicochemical characterization techniques. Moreover, this book addresses applications for both treatment and diagnosis of diseases, highlighting in vitro and in vivo findings and clinical evaluation. The chapters highlight the main barriers for drug delivery which can benefit from nanoencapsulation: the topical and oral routes. The main innovations in the field, such as gene therapy and functionalization of nanoparticles with a variety of moieties, including monoclonal antibodies for selective delivery, are discussed and illustrated with examples. Finally, the application of nanoparticles for drug delivery to cancer is reviewed considering toxicology and regulatory aspects.
Download or read book Molecular Medicines for Cancer written by Deepak Chitkara and published by CRC Press. This book was released on 2018-09-03 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of molecular medicine covers the medical interventions targeting molecular structures and mechanisms that are involved in disease progression. In cancer, several molecular mechanisms have been shown to impact its progression, aggressiveness and chemoresistance. Increasing evidence demonstrates the role of nanotechnology and outcome of molecular therapy. Several books have discussed molecular biology and mechanisms involved in cancer, but this text gives an account of molecular therapeutics in cancer relating to advancements of nanotechnology. It provides a description of the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology. Key Features: Provides current information in the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology Presents important aspects of nanotechnology in the site-specific delivery of anticancer agents Includes up to date information on oligonucleotide and gene based therapies in cancer Describes small targeted molecules, antibodies and oligonucleotides which have shown to selectively target the molecular structures thereby influencing signal transduction Facilitates discussion between researchers involved in cancer therapy and nanoscientists
Download or read book Nanostructures for Antimicrobial Therapy written by Anton Ficai and published by Elsevier. This book was released on 2017-05-29 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area
