Download or read book Enantioselective Synthesis of Beta Amino Acids written by Eusebio Juaristi and published by John Wiley & Sons. This book was released on 2005-05-06 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all facets of the synthesis of ß-amino acids As evidenced by an exponential increase in the literature published on the subject, interest in ß-amino acids has grown over the past several years. With major pharmaceutical applications, these amino acids are now studied across multiple lines of research, including combinatorial chemistry, medicinal chemistry, molecular design, proteomics, and others. This Second Edition of Enantioselective Synthesis of ß-Amino Acids updates reviews included in the First Edition while also covering new developments since its publication. The book presents detailed discussions of the most important methods for the synthesis of ß-amino acids. In most cases, the lead chemist who originally developed a method provides an authoritative description of it. In addition, Enantioselective Synthesis of ß-Amino Acids, Second Edition: * Features introductory overviews on the structural types of relevant ß-amino acid targets and salient ß-amino acids present in natural products * Dedicates several chapters to advances in the synthesis of oligomers from ß-amino acids * Includes general and practical procedures for the preparation of ß-amino acids in each chapter * Discusses the most important methods that have been recently developed for the asymmetric synthesis of cyclic and open-chain ß-amino acids * Includes a report on the preparation of libraries of enantiopure ß-amino acids using combinatorial approaches The only book of its kind available today, Enantioselective Synthesis of ß-Amino Acids, Second Edition offers upper-level students and professionals an essential resource for pharmaceutical development, medicinal chemistry, and biochemistry.

Download or read book Enantioselective Synthesis of Beta amino Acids for Inclusion Into Natural Products written by Anna Healy and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Effects of Solvent on Enantioselective Synthesis of beta amino Acids written by Elizabeth A. Cormier and published by . This book was released on 2004 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Enantioselective Synthesis of Beta Amino Alcohols and Beta Amino Acids written by Andrew Craig Donohue and published by . This book was released on 1997 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Novel Methodologies for Enantioselective Synthesis of beta amino Acid Derivatives written by Mei Liu and published by . This book was released on 2002 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Rare Americana a Very Unusual Collection of Books Pamphlets Relating to the American Revolution French and Indian War Vente New York Le 8 Juillet 1919 Heartman s written by and published by . This book was released on 1919 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Enantioselective Synthesis of Amino Acids written by Eusebio Juaristi and published by Wiley. This book was released on 1996-12-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of the importance of ß-amino acids in pharmaceutical sciences, and discusses the most important methods that have been developed for the preparation of enantiomerically pure compounds. Each method is described by the organic chemist who developed it, and so will be written with authoritative, first-hand knowledge. This title is the first book to summarize new available methodologies for preparing ß-amino acids in optically pure form, a recent development in this field. The title also provides methods for synthesizing optically pure precursors to pharmacologically active substances, including ß-lacatams.

Download or read book Process Development of a Solvent free Chemoenzymatic Reaction Sequence for the Enantioselective Synthesis of beta amino Acid Esters written by Simon Strompen and published by . This book was released on 2012 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Asymmetric Synthesis of Beta amino Acids written by Osamu Ichihara and published by . This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Asymmetric Synthesis of Beta aryl beta amino Acids and Completion of Total Synthesis of jasplakinolide written by Kent Sinching Chu and published by . This book was released on 1991 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Asymmetric Synthesis of Non Proteinogenic Amino Acids written by Ashot S. Saghyan and published by John Wiley & Sons. This book was released on 2016-09-23 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by two internationally recognized experts with an excellent track record, this much-needed reference summarizes latest research in the rapidly developing field of stereoselective synthesis of enantiomerically enriched amino acids, particularly of non-proteinogenic origin. It highlights several different catalytic and stoichiometric asymmetric methods for their synthesis and also provides information on origin, biological properties, different synthetic strategies and important applications in medicine and pharmacology. Essential reading for synthetic chemists working in the field of asymmetric synthesis, natural products and peptide synthesis, stereochemistry, medicinal chemistry, biochemistry, pharmacology, and biotechnology.

Download or read book Fluorine containing Amino Acids written by Valery P. Kukhar and published by John Wiley & Sons. This book was released on 1995-04-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, organo-fluorine chemistry has made a marked impact on the design and synthesis of a large variety of biologically active molecules, such as steroids, carbohydrates, amines, amino acids, peptides and other natural products. Naturally occurring amino acids play a pivotal role in living systems, and therefore synthetic fluorine-containing amino acids have been of significant interest to researchers working towards the understanding and modification of physiological processes. Fluorine-containing Amino Acids: is the first volume devoted to the synthesis and properties of fluorine-containing amino acids pays special attention to the preparation of enantiomerically pure acids (which are essential to the modern pharmaceutical industry) deals with a rapidly expanding field of research has been written by experienced researchers who are responsible for many developments in the field highlights the interdisciplinary nature of this topic Fluorine-containing Amino Acids is the only dedicated reference in this subject and will be essential for researchers in synthetic organic, peptide, natural product, and medicinal chemistry and biochemistry.

Download or read book Asymmetric Phase Transfer Catalysis written by Keiji Maruoka and published by John Wiley & Sons. This book was released on 2008-09-08 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by the leading expert on the topic, this is the first book to present the latest developments in this exciting field. Alongside the theoretical aspects, the top contributors provide practical protocols to give readers additional important information otherwise unavailable. A must for every synthetic chemist in academia and industry.

Download or read book Process Development of a Solvent free Chemoenzymatic Reaction Sequence for the Enantioselective Synthesis of Beta amino Acid Esters written by Simon Strompen and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Novel Methodology for the Asymmetric Synthesis of Beta lactams and Beta amino Acids written by Caroline Evans and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The first example of an intramolecular ester enolate-imine cyclisation reaction for the asymmetric synthesis of polycyclic ~-Iactams and cyclic ~-amino acid derivatives has been developed. In Chapter 1, the synthesis of monocyclic ~-Iactams using intermolecular ester enolate- imine cyclisation reactions is reviewed. The use of chiral auxiliaries contained within the ester or imino functionality to control the diastereoselectivity of the reaction is discussed, as well as enantioselective approaches. The utilization of this methodology for the synthesis of natural products such as Taxol is described, as well as the use of polymer support protocols to improve the efficiency of this reaction. In Chapter 2, the synthesis of an appropriate cyclisation substrate containing an ester and imino functionality with a chiral auxiliary fragment is reported. Appropriate conditions were established that enabled an intramolecular enolate-imine cyclisation reaction to be used for the synthesis of the tricyclic ~-Iactam benzocispentacin in good yield and excellent de. The formation of ~-amino ester side products was investigated and an explanation for the production of ~-Iactams as major products over their corresponding ~-amino esters is proposed. This protocol was then applied to the asymmetric synthesis of six benzocispentacin derivatives all with good yields and excellent de, with the configuration of one of these derivatives being confirmed by X-ray crystallography. A deprotection methodology was then established to afford their corresponding tricyclic NH-~-Iactams and cis and trans bicyclic ~-amino esters. In Chapter 3, the newly devised methodology was also applied to acyclic substrates for the synthesis of the antifungal cispentacin. The ability to access both cis- and transpentacin in both high yields and excellent de as monomers for foldamer synthesis is reported.

Download or read book Asymmetric Synthesis of beta amino Alcohols and Enantioselective Synthesis of Chiral Sulfinic Esters written by Jared Wayne Evans and published by . This book was released on 2004 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Asymmetric Synthesis and Application of Alpha Amino Acids written by Vadim A Soloshonok and published by American Chemical Society. This book was released on 2009-07-09 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the most recent and comprehensive collection of reviews on methodological developments in the field of alpha-amino acids.