Download or read book EFMC14 written by and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

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Download or read book Software for Exascale Computing SPPEXA 2016 2019 written by Hans-Joachim Bungartz and published by Springer Nature. This book was released on 2020-07-30 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book summarizes the research done and results obtained in the second funding phase of the Priority Program 1648 "Software for Exascale Computing" (SPPEXA) of the German Research Foundation (DFG) presented at the SPPEXA Symposium in Dresden during October 21-23, 2019. In that respect, it both represents a continuation of Vol. 113 in Springer’s series Lecture Notes in Computational Science and Engineering, the corresponding report of SPPEXA’s first funding phase, and provides an overview of SPPEXA’s contributions towards exascale computing in today's sumpercomputer technology. The individual chapters address one or more of the research directions (1) computational algorithms, (2) system software, (3) application software, (4) data management and exploration, (5) programming, and (6) software tools. The book has an interdisciplinary appeal: scholars from computational sub-fields in computer science, mathematics, physics, or engineering will find it of particular interest.

Download or read book Drug Discovery and Development Volume 1 written by Mukund S. Chorghade and published by Wiley-Interscience. This book was released on 2006-06-16 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: From first principles to real-world applications -- here is the first comprehensive guide to drug discovery and development Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines--from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, until now, there were no authoritative references offering a complete, fully integrated picture of the process. The only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and development--from initial conceptualization to commercialization to clinicians and medical practitioners. Volume 1: Drug Discovery describes all the steps in the discovery process, including conceptualizing a drug, creating a library of candidates for testing, screening candidates for in vitro and in vivo activity, conducting and analyzing the results of clinical trials, and modifying a drug as necessary. Volume 2: Drug Development delves into the nitty-gritty details of optimizing the synthetic route, drug manufacturing, outsourcing, and marketing--including drug coloring and delivery methods. Featuring contributions from a world-class team of experts, Drug Discovery and Development: * Features fascinating case studies, including the discovery and development of erythromycin analogs, Tagamet, and Ultiva (remifentanil) * Discusses the discovery of medications for bacterial infections, Parkinson's disease, psoriasis, peptic ulcers, atopic dermatitis, asthma, and cancer * Includes chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics Drug Discovery and Development is an indispensable working resource for industrialchemists, biologists, biochemists, and executives who work in the pharmaceutical industry.

Download or read book Rheology An Historical Perspective written by R.I. Tanner and published by Elsevier. This book was released on 1998-04-22 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The science of rheology remains a mystery to most people, even to some scientists. Some respectable dictionaries have been quite cavalier in their attitude to the science, the small Collins Gem dictionary, for example, being quite happy to inform us that a Rhea is an three-toed South American ostrich, whilst at the same time offering no definition of rheology. This maybe due to the fact that the science is interdisciplinary and does not fit well into any one of the historical disciplines. This book contains an in-depth study of the history of rheology, beginning with the statements of Heraclitus, Confucius and the prophetess Deborah. It also emphasises the distinctive contributions of Newton, Hooke, Boltzmann, Maxwell, Kelvin and others, and culminates in the flourishing activity in the second half of this century. Features of this book: • Is the only book on the subject • Prevents the rediscovery of results already made • Will educate newcomers to the field to the rich heritage in even a relatively recent science like rheology. The book will be invaluable for science and scientific history libraries and will also be of interest to rheologists, and scientists working in the polymer processing, food, lubrication, detergent and similar industries.

Download or read book Target Discovery and Validation written by Alleyn T. Plowright and published by John Wiley & Sons. This book was released on 2020-02-18 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling. Throughout, the authors highlight a range of diverse approaches, and target validation studies reveal how these methods can support academic and drug discovery scientists in their target discovery and validation research. This resource: -Offers a guide to identifying and validating targets, a key enabling technology without which no new drug development is possible -Presents the information needed for choosing the appropriate assay method from the ever-growing range of available options -Provides practical examples from recent drug development projects, e. g. in kinase inhibitor profiling Written for medicinal chemists, pharmaceutical professionals, biochemists, biotechnology professionals, and pharmaceutical chemists, Target Discovery and Validation explores the current methods for the identification and validation of drug targets in one comrpehensive volume. It also includes numerous practical examples.

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Download or read book Virtual Reality in Health and Rehabilitation written by Christopher M. Hayre and published by CRC Press. This book was released on 2020-12-22 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book focuses on the role and use of VR for healthcare professions in both health and rehabilitation settings. It is also offers future trends of other emerging technology within medicine and allied health professions. This text draws on expertise of leading medical practitioners and researchers who utilise such VR technologies in their practices to enhance patient/service user outcomes. Research and practical evidence is presented with a strong applied emphasis to further enhance the use VR technologies within the community, the hospital and in education environment(s). The book may also be used to influence policymakers on how healthcare delivery is offered.

Download or read book Fluorescence Methods for Investigation of Living Cells and Microorganisms written by Natalia Grigoryeva and published by BoD – Books on Demand. This book was released on 2020-09 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorescence methods play a leading role in the investigation of biological objects. They are the only non-destructive methods for investigating living cells and microorganisms in vivo. Using intrinsic and artificial fluorescence methods provides deep insight into mechanisms underlying physiological and biochemical processes. This book covers a wide range of modern methods involved in experimental biology. It illustrates the use of fluorescence microscopy and spectroscopy, confocal laser scanning microscopy, flow cytometry, delayed fluorescence, pulse-amplitude-modulation fluorometry, and fluorescent dye staining protocols. This book provides an overview of practical and theoretical aspects of fluorescence methods and their successful application in the investigation of static and dynamic processes in living cells and microorganisms.

Download or read book Machine Learning for Medical Image Reconstruction written by Farah Deeba and published by Springer Nature. This book was released on 2020-10-21 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the Third International Workshop on Machine Learning for Medical Reconstruction, MLMIR 2020, held in conjunction with MICCAI 2020, in Lima, Peru, in October 2020. The workshop was held virtually. The 15 papers presented were carefully reviewed and selected from 18 submissions. The papers are organized in the following topical sections: deep learning for magnetic resonance imaging and deep learning for general image reconstruction.

Download or read book Intervertebral Disc Regeneration written by Benjamin Gantenbein and published by Mdpi AG. This book was released on 2022-01-11 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a brief snapshot of recent research on the subject of intervertebral disc degeneration and how this specific organ could be regenerated. It provides stimuli to the reader in representing research from different angles in this cross-disciplinary field of spine surgeons, mechanical engineers and biologists. In particular, it is instructive as to how disc herniations could be successfully induced in vitro and, also, to how novel cell-based therapies using rare autochthonous stem cells could potentially be used in the future.

Download or read book Sensorimotor Rehabilitation written by and published by Elsevier. This book was released on 2015-04-14 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Progress in Brain Research focuses on Sensorimotor Rehabilitation. This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields