Download or read book Efficient Use of Polarisation in Magnetic Resonance Imaging of Hyperpolarised Noble Gases written by Martin Heiner Deppe and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Optimization of Hyperpolarized Noble Gas Magnetic Resonance Imaging written by Lei Zhao and published by . This book was released on 2000 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hyperpolarized and Inert Gas MRI written by Mitchell S. Albert and published by Academic Press. This book was released on 2016-11-17 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyperpolarized and Inert Gas MRI: Theory and Applications in Research and Medicine is the first comprehensive volume published on HP gas MRI. Since the 1990’s, when HP gas MRI was invented by Dr. Albert and his colleagues, the HP gas MRI field has grown dramatically. The technique has proven to be a useful tool for diagnosis, disease staging, and therapy evaluation for obstructive lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. HP gas MRI has also been developed for functional imaging of the brain and is presently being developed for molecular imaging, including molecules associated with lung cancer, breast cancer, and Alzheimer’s disease. Taking into account the ongoing growth of this field and the potential for future clinical applications, the book pulls together the most relevant and cutting-edge research available in HP gas MRI into one resource. Presents the most comprehensive, relevant, and accurate information on HP gas MRI Co-edited by the co-inventor of HP gas MRI, Dr. Albert, with chapter authors who are the leading experts in their respective sub-disciplines Serves as a foundation of understanding of HP gas MRI for researchers and clinicians involved in research, technology development, and clinical use with HP gas MRI Covers all hyperpolarized gases, including helium, the gas with which the majority of HP gas MRI has been conducted
Download or read book Hyperpolarized Carbon 13 Magnetic Resonance Imaging and Spectroscopy written by Peder Larson and published by Academic Press. This book was released on 2021-11-28 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: MRI with hyperpolarized carbon-13 agents is a powerful emerging imaging modality that can measure real-time metabolism in cells, animals, and humans. It uses endogenous, non-toxic contrast agents that a hyperpolarized, resulting in up to 100,000-fold increases in sensitivity. This technique uses no ionizing radiation, and is being applied in a range of human trials. It’s primary use is for metabolic imaging, but it can also measure perfusion, pH, and necrosis. Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy is designed to be a one stop shop for understanding hyperpolarized 13C MRI. This book explains the principles of this imaging modality, the requirements for performing studies, shows how to interpret the results, and gives an overview of current biomedical applications. It is suitable for engineers, scientists and clinicians in radiology and biomedical imaging who want to understand this technology. Presents the physics and hardware of dissolution dynamic nuclear polarization Explains the behaviour of hyperpolarized carbon-13 agents and how to image them Detailed guidance on experimental design and data interpretation Identifies promising and potential applications of hyperpolarized carbon-13 MR
Download or read book Berkeley Lab Research Review written by and published by . This book was released on 1996 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solar Polarization 3 written by Javier Trujillo Bueno and published by . This book was released on 2003 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dynamic Hyperpolarized Nuclear Magnetic Resonance written by Thomas Jue and published by Springer Nature. This book was released on 2021-05-21 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book in the series to focus on dynamic hyperpolarized nuclear magnetic resonance, a burgeoning topic in biophysics. The volume follows the format and style of the Handbook of Modern Biophysics series and expands on topics already discussed in previous volumes. It builds a theoretical and experimental framework for students and researchers who wish to investigate the biophysics and biomedical application of dynamic hyperpolarized NMR. All contributors are internationally recognized experts, lead the dynamic hyperpolarized NMR field, and have first-hand knowledge of the chapter material. The book covers the following topics: Hyperpolarization by dissolution Dynamic Nuclear Polarization Design considerations for implementing a hyperpolarizer Chemical Shift Imaging with Dynamic Hyperpolarized NMR Signal Sampling Strategies in Dynamic Hyperpolarized NMR Kinetic Modeling of Enzymatic Reactions in Analyzing Hyperpolarized NMR Data Using Hyperpolarized NMR to Understand Biochemistry from Cells to Humans Innovating Metabolic Biomarkers for Hyperpolarized NMR New Insights into Metabolic Regulation from Hyperpolarized 13C MRS/MRI Studies Novel Views on Heart Function from Dynamic Hyperpolarized NMR Insights on Lactate Metabolism in Skeletal Muscle based on 13C Dynamic Nuclear Polarization Studies About the Editors Dirk Mayer is Professor of Diagnostic Radiology and Nuclear Medicine at the University of Maryland and is the Director of Metabolic Imaging. He is a recognized expert on dynamic nuclear polarization (DNP) MRI-based imaging techniques and has optimized acquisition and reconstruction techniques, has constructed kinetic modeling for quantitative analysis, and has developing new probes. Thomas Jue is Professor of Biochemistry and Molecular Medicine at the University of California Davis. He is an internationally recognized expert in developing and applying magnetic resonance techniques to study animal as well as human physiology in vivo. He served as a Chair of the Biophysics Graduate Group Program at UC Davis, where he started to redesign a graduate curriculum that balances physical science/mathematics formalism and biomedical perspective in order to promote interest at the interface of physical science, engineering, mathematics, biology, and medicine. The Handbook of Modern Biophysics represents an aspect of that effort.
Download or read book Textbook of in vivo Imaging in Vertebrates written by Vasilis Ntziachristos and published by John Wiley & Sons. This book was released on 2007-08-20 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the new imaging techniques being developed to monitor physiological, cellular and subcellular function within living animals. This exciting field of imaging science brings together physics, chemistry, engineering, biology and medicine to yield powerful and versatile imaging approaches. By combining advanced non-invasive imaging technologies with new mechanisms for visualizing biochemical events and protein and gene function, non-invasive vertebrate imaging enables the in vivo study of biology and offers rapid routes from basic discovery to drug development and clinical application. Combined with the availability of an increasing number of animal models of human disease, and the ability to perform longitudinal studies of disease evolution and of the long-term effects of therapeutic procedures, this new technology offers the next generation of tools for biomedical research. Well illustrated, largely in colour, the book reviews the most common and technologically advanced methods for vertebrate imaging, presented in a clear, comprehensive format. The basic principles are described, followed by several examples of the use of imaging in the study of living multicellular organisms, concentrating on small animal models of human diseases. The book illustrates: The types of information that can be obtained with modern in vivo imaging; The substitution of imaging methods for more destructive histological techniques; The advantages conferred by in vivo imaging in building a more accurate picture of the response of tissues to stimuli over time while significantly reducing the number of animals required for such studies. Part 1 describes current techniques in in vivo imaging, providing specialists and laboratory scientists from all disciplines with clear and helpful information regarding the tools available for their specific research field. Part 2 looks in more detail at imaging organ development and function, covering the brain, heart, lung and others. Part 3 describes the use of imaging to monitor various new types of therapy, following the reaction in an individual organism over time, e.g. after gene or cell therapy. Most chapters are written by teams of physicists and biologists, giving a balanced coherent description of each technique and its potential applications.
Download or read book Applications of Hyperpolarisation in Magnetic Resonance Imaging written by Ralph William Adams and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hyperpolarized Xenon 129 Magnetic Resonance written by Thomas Meersmann and published by Royal Society of Chemistry. This book was released on 2015-04-14 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing the first comprehensive book on the current state of hyperpolarized Xenon-129 NMR and MRI, this book is guaranteed to appeal to a wide range of scientists interested in this growing field. It is intended to create synergy between the various communities working with this noble gas. Covering all topics from the production of the hyperpolarized gas to its applications, the editors have invited a leading team of experts to combine the physical chemistry within the various topics and across disciplines. The scope will range from the fundamental aspects of optical pumping to practical aspects of hyperpolarizers and hp-xenon handling. The applications section will focus on hyperpolarized xenon-129 detected in the dissolved phase or micro porous media where the chemical shift of xenon-129 can be used as a diagnostic probe. Appealing to researchers in the biomedical field and materials sciences, this reference book will provide background reading and future looking material in one place.
Download or read book STTR An Assessment of the Small Business Technology Transfer Program written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-01-11 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today's knowledge economy is driven in large part by the nation's capacity to innovate. One of the defining features of the U.S. economy is a high level of entrepreneurial activity. Entrepreneurs in the United States see opportunities and are willing and able to assume risk to bring new welfare-enhancing, wealth-generating technologies to the market. Yet, although discoveries in areas such as genomics, bioinformatics, and nanotechnology present new opportunities, converting these discoveries into innovations for the market involves substantial challenges. The American capacity for innovation can be strengthened by addressing the challenges faced by entrepreneurs. Public-private partnerships are one means to help entrepreneurs bring new ideas to market. The Small Business Technology Transfer (STTR) and the Small Business Innovation Research (SBIR) program form one of the largest examples of U.S. public-private partnerships. In the SBIR Reauthorization Act of 2000, Congress tasked the National Research Council with undertaking a comprehensive study of how the SBIR program has stimulated technological innovation and used small businesses to meet federal research and development needs and with recommending further improvements to the program. When reauthorizing the SBIR and STTR programs in 2011, Congress expanded the study mandate to include a review of the STTR program. This report builds on the methodology and outcomes from the previous review of SBIR and assesses the STTR program.
Download or read book Nuclear Magnetic Resonance written by G A Webb and published by Royal Society of Chemistry. This book was released on 2009-10-16 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a spectroscopic method, nuclear magnetic resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: ""NMR of Proteins and Nucleic Acids"" and ""NMR of Carbohydrates, Lipids and Membranes"". For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an invaluable source of current methods and applications.
Download or read book Molecular Imaging written by Brian D. Ross and published by Academic Press. This book was released on 2021-08-03 with total page 1872 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data Concepts illustrated with over 600 color figures and molecular-imaging examples Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications
Download or read book Gas Phase NMR written by Karol Jackowski and published by Royal Society of Chemistry. This book was released on 2016-02-09 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the recent NMR studies with the application of gaseous molecules. Among the comprehensively discussed aspects of the area it includes in particular: new multinuclear experiments that deliver spectral parameters of isolated molecules and provide the most accurate values of nuclear magnetic shielding, isotropic spin–spin coupling and relaxation times; advanced, precise and correct theoretical descriptions of spectral parameters of molecules as well as the application of gas-phase NMR measurements to chemical analysis and medicine. The progress of research in these fields is enormous and has rapidly changed our knowledge and understanding of molecular parameters in NMR spectroscopy. For example, accurate studies of the shielding for isolated molecules allow the exact determination of nuclear magnetic dipole moments, the calculated values of spectral parameters can be verified by precise gas-phase NMR measurements, and the application of hyperpolarized noble gases provides excellent MRI pictures of lungs. Aimed at graduates and researchers in spectroscopy, analytical chemistry and those researching the applications of NMR in medicine, this book presents the connections between sophisticated experiments, the theory of magnetic parameters and the exploration of new methods in practice.
Download or read book Nuclear Magnetic Resonance of a Hyperpolarized Gas written by Austin R. Ziltz and published by . This book was released on 2008 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, there have been many advances in laser technology and an increase in the applications of polarized noble gases. Present here the development of a system to produce high polarizations in low density, gas phase samples of noble gases via Spin-Exchange Optical Pumping.
Download or read book Annual Reports on NMR Spectroscopy written by Graham A. Webb and published by Academic Press. This book was released on 2014-04-23 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has gained such significance as NMR spectroscopy. It is used in all branches of science in which precise structural determination is required and in which the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and non-specialist alike to become familiar with new techniques and applications of NMR spectroscopy. This is an invaluable resource for organic, inorganic, analytical and physical chemists, biochemists, structural biologists, physicists, and all those studying and using NMR spectroscopy. Volume 82 of Annual Reports on NMR Spectroscopy focuses on the analytical tools used by chemists and physicists. Taken together with other volumes of this series, it provides an excellent account of progress in NMR and its many applications for anyone using NMR.
Download or read book Imaging written by R. Graham Barr and published by European Respiratory Society. This book was released on 2016-03-01 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging is key to the screening and diagnosis of many respiratory conditions. It is also an area of significant debate, particularly with regard to questions surrounding safety and overuse. This Monograph will be of interest to pulmonologists in all areas of respiratory medicine. The book covers two main areas: imaging methodology and safety; and imaging use in specific respiratory conditions. Chapters will include: safety issues in CT and MRI, MRI methods, radionuclide imaging, chest radiography, COPD, cystic fibrosis, asthma, lung cancer, pulmonary hypertension, and much more.
