Download or read book Traumatic Brain and Spinal Cord Injury written by Cristina Morganti-Kossmann and published by Cambridge University Press. This book was released on 2012-07-19 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.

Download or read book Quantitative MRI of the Spinal Cord written by Julien Cohen-Adad and published by Academic Press. This book was released on 2014-01-16 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory's applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord. - Chapters authored by international experts in the field of MRI of the spinal cord - Contains "cooking recipes—examples of imaging parameters for each quantitative technique—designed to aid researchers and clinicians in using them in practice - Ideal for clinical settings

Download or read book The Spinal Cord written by Charles Watson and published by Academic Press. This book was released on 2009-11-27 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many hundreds of thousands suffer spinal cord injuries leading to loss of sensation and motor function in the body below the point of injury. Spinal cord research has made some significant strides towards new treatment methods, and is a focus of many laboratories worldwide. In addition, research on the involvement of the spinal cord in pain and the abilities of nervous tissue in the spine to regenerate has increasingly been on the forefront of biomedical research in the past years. The Spinal Cord, a collaboration with the Christopher and Dana Reeve Foundation, is the first comprehensive book on the anatomy of the mammalian spinal cord. Tens of thousands of articles and dozens of books are published on this subject each year, and a great deal of experimental work has been carried out on the rat spinal cord. Despite this, there is no comprehensive and authoritative atlas of the mammalian spinal cord. Almost all of the fine details of spinal cord anatomy must be searched for in journal articles on particular subjects. This book addresses this need by providing both a comprehensive reference on the mammalian spinal cord and a comparative atlas of both rat and mouse spinal cords in one convenient source. The book provides a descriptive survey of the details of mammalian spinal cord anatomy, focusing on the rat with many illustrations from the leading experts in the field and atlases of the rat and the mouse spinal cord. The rat and mouse spinal cord atlas chapters include photographs of Nissl stained transverse sections from each of the spinal cord segments (obtained from a single unfixed spinal cord), detailed diagrams of each of the spinal cord segments pictured, delineating the laminae of Rexed and all other significant neuronal groupings at each level and photographs of additional sections displaying markers such as acetylcholinesterase (AChE), calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), enkephalin, calcitonin gene-related peptide (CGRP), and neuronal nuclear protein (NeuN). - The text provides a detailed account of the anatomy of the mammalian spinal cord and surrounding musculoskeletal elements - The major topics addressed are: development of the spinal cord; the gross anatomy of the spinal cord and its meninges; spinal nerves, nerve roots, and dorsal root ganglia; the vertebral column, vertebral joints, and vertebral muscles; blood supply of the spinal cord; cytoarchitecture and chemoarchitecture of the spinal gray matter; musculotopic anatomy of motoneuron groups; tracts connecting the brain and spinal cord; spinospinal pathways; sympathetic and parasympathetic elements in the spinal cord; neuronal groups and pathways that control micturition; the anatomy of spinal cord injury in experimental animals - The atlas of the rat and mouse spinal cord has the following features: Photographs of Nissl stained transverse sections from each of 34 spinal segments for the rat and mouse; Detailed diagrams of each of the 34 spinal segments for rat and mouse, delineating the laminae of Rexed and all other significant neuronal groupings at each level. ; Alongside each of the 34 Nissl stained segments, there are additional sections displaying markers such as acetylcholinesterase, calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), and neuronal nuclear protein (NeuN) - All the major motoneuron clusters are identified in relation to the individual muscles or muscle groups they supply

Download or read book Exploring the Thalamus and Its Role in Cortical Function written by S. Murray Sherman and published by MIT Press (MA). This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thalamus plays a critical role in perceptual processing, but many questions remain about what thalamic activities contribute to sensory and motor functions. In this book, two pioneers in research on the thalamus examine the close two-way relationships between thalamus and cerebral cortex and look at the distinctive functions of the links between the thalamus and the rest of the brain. Countering the dominant "corticocentric" approach to understanding the cerebral cortex—which does not recognize that all neocortical areas receive important inputs from the thalamus and send outputs to lower motor centers—S. Murray Sherman and R. W. Guillery argue for a reappraisal of the way we think about the cortex and its interactions with the rest of the brain. The book defines some of the functional categories critical to understanding thalamic functions, including the distinctions between drivers (pathways that carry messages to the cortex) and modulators (which can change the pattern of transmission) and between first-order and higher-order thalamic relays—the former receiving ascending drivers and the latter receiving cortical drivers. This second edition further develops these distinctions with expanded emphasis throughout the book on the role of the thalamus in cortical function. An important new chapter suggests a structural basis for linking perception and action, supplying supporting evidence for a link often overlooked in current views of perceptual processing.

Download or read book Spinal Cord Injury SCI Repair Strategies written by Giuseppe Perale and published by Woodhead Publishing. This book was released on 2019-10-30 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair. - Covers current and future repair strategies for spinal cord injury repair - Focuses on key research trends, clinics, biology and engineering - Provides fundamentals on regenerative engineering and tissue engineering

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Download or read book Brain Repair After Stroke written by Steven C. Cramer and published by Cambridge University Press. This book was released on 2010-10-28 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.

Download or read book Sports Related Concussions in Youth written by National Research Council and published by National Academies Press. This book was released on 2014-02-04 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade, few subjects at the intersection of medicine and sports have generated as much public interest as sports-related concussions - especially among youth. Despite growing awareness of sports-related concussions and campaigns to educate athletes, coaches, physicians, and parents of young athletes about concussion recognition and management, confusion and controversy persist in many areas. Currently, diagnosis is based primarily on the symptoms reported by the individual rather than on objective diagnostic markers, and there is little empirical evidence for the optimal degree and duration of physical rest needed to promote recovery or the best timing and approach for returning to full physical activity. Sports-Related Concussions in Youth: Improving the Science, Changing the Culture reviews the science of sports-related concussions in youth from elementary school through young adulthood, as well as in military personnel and their dependents. This report recommends actions that can be taken by a range of audiences - including research funding agencies, legislatures, state and school superintendents and athletic directors, military organizations, and equipment manufacturers, as well as youth who participate in sports and their parents - to improve what is known about concussions and to reduce their occurrence. Sports-Related Concussions in Youth finds that while some studies provide useful information, much remains unknown about the extent of concussions in youth; how to diagnose, manage, and prevent concussions; and the short- and long-term consequences of concussions as well as repetitive head impacts that do not result in concussion symptoms. The culture of sports negatively influences athletes' self-reporting of concussion symptoms and their adherence to return-to-play guidance. Athletes, their teammates, and, in some cases, coaches and parents may not fully appreciate the health threats posed by concussions. Similarly, military recruits are immersed in a culture that includes devotion to duty and service before self, and the critical nature of concussions may often go unheeded. According to Sports-Related Concussions in Youth, if the youth sports community can adopt the belief that concussions are serious injuries and emphasize care for players with concussions until they are fully recovered, then the culture in which these athletes perform and compete will become much safer. Improving understanding of the extent, causes, effects, and prevention of sports-related concussions is vitally important for the health and well-being of youth athletes. The findings and recommendations in this report set a direction for research to reach this goal.

Download or read book Clinical Neuroanatomy and Neuroscience E Book written by Estomih Mtui and published by Elsevier Health Sciences. This book was released on 2011-04-14 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neuroanatomy and Neuroscience by Drs. M. J. T. FitzGerald, Gregory Gruener, and Estomih Mtui, already known as the most richly illustrated book available to help you through the complexity of neuroscience, brings you improved online resources with this updated edition. You’ll find the additional content on Student Consult includes one detailed tutorial for each chapter, 200 USMLE Step I questions, and MRI 3-plane sequences. With clear visual images and concise discussions accompanying the text’s 30 case studies, this reference does an impressive job of integrating clinical neuroanatomy with the clinical application of neuroscience. Aid your comprehension of this challenging subject by viewing more than 400 explanatory illustrations drawn by the same meticulous artists who illustrated Gray’s Anatomy for Students. Get a complete picture of different disorders such as Alzheimer’s disease and brain tumors by reading about the structure, function, and malfunction of each component of the nervous system. Grasp new concepts effortlessly with this book’s superb organization that arranges chapters by anatomical area and uses Opening Summaries, Study Guidelines, Core Information Boxes, Clinical Panels, and 23 "flow diagrams," to simplify the integration of information. Use this unique learning tool to help you through your classes and prep for your exams, and know that these kind of encompassing tutorials are not usually available for self-study. Access outstanding online tutorials on Student Consult that deliver a slide show on relevant topics such as Nuclear Magnetic Resonance and Arterial Supply of the Forebrain. Confidently absorb all the material you need to know as, for the first time ever, this edition was reviewed by a panel of international Student Advisors whose comments were added where relevant. Understand the clinical consequences of physical or inflammatory damage to nervous tissues by reviewing 30 case studies.

Download or read book Spinal Cord Plasticity written by Michael M. Patterson and published by Springer. This book was released on 2012-10-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of spinal cord plasticity has become a very actively researched field. The spinal cord has long been known to organize reflex patterns and serve as the major transmission pathway for sensory and motor nerve impulses. However, the role of the spinal cord in information processing and in experience driven alterations is generally not recognized. With recent advances in neural recording techniques, behavioral technologies and neural tracing and imaging methods has come the ability to better assess the role of the spinal cord in behavioral control and alteration. The discoveries in recent years have been revolutionary. Alterations due to nociceptive inputs, simple learning paradigms and repetitive inputs have now been documented and their mechanisms are being elucidated. These findings have important clinical implications. The development of pathological pain after a spinal cord injury likely depends on the sensitization of neurons within the spinal cord. The capacity of the spinal cord to change as a function of experience, and adapt to new environmental relations, also affects the recovery locomotive function after a spinal cord injury. Mechanisms within the spinal cord can support stepping and the capacity for this behavior depends on behavioral training. By taking advantage of the plasticity inherent within the spinal cord, rehabilitative procedures may foster the recovery of function.

Download or read book Botulinum Toxin Therapy written by Scott M. Whitcup and published by Springer Nature. This book was released on 2021-01-05 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a rapidly progressing field, Botulinum Toxin Therapy provides both clinicians and basic researchers with the latest science on the structure and function of botulinum toxins and the use of these toxins to treat a wide variety of diseases. Part 1 of the book reviews the basic science of botulinum toxins including advances in our understanding of the molecular structure and mechanism of action of botulinum toxins. This section also discusses the manufacturing and formulation of botulinum toxins for clinical use and the development of novel therapeutic toxins for the future. Part 2 reviews the use of botulinum toxins in clinical practice. It discusses the clinical pharmacology of botulinum toxin drugs and their use in a wide variety of clinical conditions including headache, spasticity, pain, disorders of the genitourinary and gastrointestinal tract, strabismus, and medical aesthetics.

Download or read book Brain Computer Interfaces written by Jonathan Wolpaw and published by Oxford University Press. This book was released on 2012-01-24 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: A recognizable surge in the field of Brain Computer Interface (BCI) research and development has emerged in the past two decades. This book is intended to provide an introduction to and summary of essentially all major aspects of BCI research and development. Its goal is to be a comprehensive, balanced, and coordinated presentation of the field's key principles, current practice, and future prospects.

Download or read book Innate written by Kevin J. Mitchell and published by Princeton University Press. This book was released on 2020-03-31 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: "What makes you the way you are--and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world. We all share a genetic program for making a human brain, and the program for making a brain like yours is specifically encoded in your DNA. But, as Mitchell explains, the way that program plays out is affected by random processes of development that manifest uniquely in each person, even identical twins. The key insight of Innate is that the combination of these developmental and genetic variations creates innate differences in how our brains are wired--differences that impact all aspects of our psychology--and this insight promises to transform the way we see the interplay of nature and nurture. Innate also explores the genetic and neural underpinnings of disorders such as autism, schizophrenia, and epilepsy, and how our understanding of these conditions is being revolutionized. In addition, the book examines the social and ethical implications of these ideas and of new technologies that may soon offer the means to predict or manipulate human traits. Compelling and original, Innate will change the way you think about why and how we are who we are."--Provided by the publisher.

Download or read book CNS Regeneration written by Mark H. Tuszynski and published by Academic Press. This book was released on 1999 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: CNS Regeneration focuses on some of the leading current neurological disease models and methods for promoting central nervous system regeneration. Editors and authors are experts in the field, with experience in basic as well as applied neuroscience. In a comprehensive, logical manner, the book unites important basic science advances in neuroscience with novel medical strategies. The first comprehensive, authoritative volume on the topic of CNS regeneration Reviews current therapeutic approaches Editors and authors are experts in the field Appeals to those interested in basic science as well as those concerned with its medical application

Download or read book Translational Neuroscience written by Mark H. Tuszynski and published by Springer. This book was released on 2016-03-08 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology, neuro devices, rehabilitation and others over the last 20 years have generated unprecedented opportunities to treat heretofore untreatable disorders of the nervous system. This book provides a wide-ranging yet detailed sample of many of these efforts, together with the methods for pursuing clinical translation and assessing clinical outcomes. Among the topics covered are Alzheimer’s disease, Parkinson’s disease, stroke, multiple sclerosis, epilepsy, motor neuron disease, pain, inborn errors of metabolism, brain tumors, spinal cord injury, neuroprosthetics, rehabilitation and clinical trial design/consideration. Translational Neuroscience is aimed at basic neuroscientists, translational neuroscientists and clinicians who seek to gain a perspective on the nature and promise of translational therapies in the current era. Both students and established professionals will benefit from the content.

Download or read book The Human Nervous System written by Charles R. Noback and published by Springer Science & Business Media. This book was released on 2005 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this work, the authors integrate three major basic themes of neuroscience to serve as an introduction and review of the subject.

Download or read book Reconstructive Neurosurgery written by Wen-Ta Chiu and published by Springer Science & Business Media. This book was released on 2009-01-22 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: International experts present in this volume advances in reconstructive neurosurgery focusing on the fields of neurotrauma and neurodegenerative disorders. The highlights include building an international strategy for risk reduction, documentating an multidisciplinary approach towards restoration of function in paraplegic spinal cord-injured patients, describing a new approach for statistical analysis in traumatic brain injury trials, describing blood flow changes in diffuse brain injury, discussing rehabilitation programs in Germany following acute brain injury, describing research data form Taiwan on neurotrauma, showing the neuropsychiatric effects from deep brain stimuation fro ovement disorders, difining the role played by imanging for deep brain stimulation targeting in mental illness, using radiosurgery in decompresssion in the treatment of trigeminal neuralgia, describing the development of radiosurgery from brain to the spine, listing new transgenic animal models of Parkinson's disease, discussing gene therapy for neuropathic pain and Parkinson's disease, and finally, discussing constrained-induced movement therapy fro stroke patients, and endovascular therapy for cerebrovenous disorders.