Download or read book Effects of Abrupt Changes in Microfluidic Geometry on Complex Biological Fluid Flows written by Shelly Gulati and published by . This book was released on 2006 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Complex Fluid Flows in Microfluidics written by Francisco José Galindo-Rosales and published by Springer. This book was released on 2017-05-26 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph contains expert knowledge on complex fluid-flows in microfluidic devices. The topical spectrum includes, but is not limited to, aspects such as the analysis, experimental characterization, numerical simulations and numerical optimization. The target audience primarily comprises researchers who intend to embark on activities in microfluidics. The book can also be beneficial as supplementary reading in graduate courses.
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2007 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Micro Drops and Digital Microfluidics written by Jean Berthier and published by Elsevier. This book was released on 2008-03-20 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: After spending over 12 years developing new microsystems for biotechnology – especially concerned with the microfluidic aspects of these devices – Jean Berthier is considered a leading authority in the field. Now, following the success of his book, Microfluidics for Biotechnology, Dr. Berthier returns to explain how new miniaturization techniques have dramatically expanded the area of microfluidic applications and microsystems into microdrops and digital microfluidics.Engineers interested in designing more versatile microsystems and students who seek to learn the fundamentals of microfluidics will all appreciate the wide-range of information found within Microdrops and Digital Microfluidics. The most recent developments in digital microfluidics are described in clear detail, with a specific focus on the computational, theoretical and experimental study of microdrops. - Over 500 equations and more than 400 illustrations - Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as "microdrops" and separately from "nanodrops" - A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates - A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces - Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow) - A fresh perspective on the future of microfluidics
Download or read book Microfluidics History Theory and Applications written by William B. J. Zimmerman and published by Springer Science & Business Media. This book was released on 2006-06-27 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics is a microtechnological field dealing with the precise transport of fluids (liquids or gases) in small amounts (e.g. microliters, nanoliters or even picoliters). This book provides a useful introduction into this burgeoning field, and a specific application of microfluidics is presented. It also gives a survey of microfluidics.
Download or read book Immiscible Liquid liquid Displacement in Microfluidic Channels written by Hyundo Lee and published by . This book was released on 2017 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Displacement of a fluid by an immiscible fluid occurs in various situations such as oil recovery in underground reservoirs, transport in the human body, and other interconnected network systems and porous media. We are motivated by oil recovery processes in geological porous media that take place at the micrometer scale, and focus in particular on the effects of wettability and geometry of microstructures on immiscible liquid-liquid displacements, that result from interactions in oil-water-rock systems. Microfluidic devices, micromodels, have been proposed as experimental test beds for reproducing flows in oil reservoirs in laboratory environments since they offer fine control over geometry and chemistry, and therefore provide insights into their effects on the process. These microfluidic devices are usually two-dimensional and transparent, with a simplified porous network designed to visualize and study fluid behavior in porous media. In oil reservoir research, the microfluidic test beds reflect underground oil reservoir conditions, for example, porosity, permeability, and wettability. The work in this thesis focuses on simple, additive micromodel fabrication techniques to build robust and reproducible structures in microfluidic channels and on the basic and fundamental understanding of immiscible displacement processes with simplified models and controlled flow conditions. We introduce two simple micromodel fabrication methods that can provide design flexibility with photopatterning, the ability to tailor wetting properties, and the calcium carbonate structure that is the most common constituent of oil reservoirs. We utilize a microscope projection lithography to construct polymeric structures with pre-defined wetting properties using a UV-initiated copolymerization method, and we are also able to make real-rock carbonate micromodels by incorporating calcium carbonate seed particles into microstructures and growing them with a supersaturated calcium carbonate solution. Using the micromodel fabrication methods thus developed, we have systematically explored oil-water immiscible displacement processes in a controlled manner with respect to various geometric and wettability conditions. With the fact that our flow experiment is in a small capillary number regime, we formulate a mathematical model for the oil-water displacement process with photopatterned structures of simple geometry and periodic patterns, and verify our theoretical model by matching it with our experimental observations, and we also conduct oil recovery model studies with encapsulated oil pockets with aqueous surfactant solution flooding. Lastly, based on the experience of calcium carbonate/hydrogel composite structuring and calcium carbonate growth from the structure, we expand our work and develop a method of making drug-laden hydrogel particles. By developing flexible methods to make microfluidic devices for immiscible fluids displacement study and investigation on the displacement process, we have been able to realize that microfluidic research with simplified conditions can enhance fundamental understanding of multiphase flow in natural, complex porous media.
Download or read book Study of Immiscible Liquid liquid Microfluidic Flow Using SPH based Explicit Numerical Simulation written by Hamideh Elekaei Behjati and published by . This book was released on 2015 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic devices are utilized in a wide range of applications, including micro-electromechanical devices, drug delivery, biological diagnostics and micro-fuel cell systems. Of particular interest here are liquid-liquid microfluidic systems; which are used in drug discovery, food and oil industry amongst others. Increased understanding of the fundamentals of flows in such devices and an improved capacity to design them can come from modelling. In the case of liquid-liquid flows in microfluidic systems, it is necessary to explicitly model the behaviour of the individual liquid phases. Such explicit numerical simulation (ENS) as it is termed requires advanced numerical methods that are able to evaluate flow involving multiple deforming fluid domains within often complex boundaries. Smoothed Particle Hydrodynamics (SPH), a Lagrangian meshless method, is particularly suitable for such problems. This use of a CFD allows determination of parameters that are difficult to determine experimentally because of the challenges faced in microfabrication. The study reported in this thesis addresses these concerns through development of a new SPH-based model to correctly capture the immiscible liquid-liquid interfaces in general and for a microfluidic hydrodynamic focusing system in particular. The model includes surface tension to enforce immiscibility between different liquids based on a new immiscibility model, enforces strict incompressibility, and allows for arbitrary fluid constitutive models. This work presents a detailed study on the effects of various flow parameters including flowrate ratio, viscosity ratio and capillary number of each liquid phase, and geometry characteristics such as channel size, width ratio, and the angle between the inlet main and side channels on the flow dynamics and topological changes of the multiphase microfluidic system. According to our findings, both flowrate quantity and flowrate ratio affect the droplet length in the dripping regime and a large viscosity ratio imposes an increase in the flowrate of the continuous phase with the same capillary number of the dispersed phase to attain dripping regime in the outlet channel. Also, increasing the side channel width causes longer droplets, and the right-angled design makes the most efficient focusing behaviour. This study will provide great insights in designing microfluidic devices involving immiscible liquid-liquid flows.
Download or read book Theoretical Microfluidics written by Henrik Bruus and published by Oxford University Press. This book was released on 2007-09-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics is a young and rapidly expanding scientific discipline, which deals with fluids and solutions in miniaturized systems, the so-called lab-on-a-chip systems. It has applications in chemical engineering, pharmaceutics, biotechnology and medicine. As the lab-on-a-chip systems grow in complexity, a proper theoretical understanding becomes increasingly important. The basic idea of the book is to provide a self-contained formulation of the theoretical framework of microfluidics, and at the same time give physical motivation and examples from lab-on-a-chip technology. After three chapters introducing microfluidics, the governing equations for mass, momentum and energy, and some basic flow solutions, the following 14 chapters treat hydraulic resistance/compliance, diffusion/dispersion, time-dependent flow, capillarity, electro- and magneto-hydrodynamics, thermal transport, two-phase flow, complex flow patterns and acousto-fluidics, as well as the new fields of opto- and nano-fluidics. Throughout the book simple models with analytical solutions are presented to provide the student with a thorough physical understanding of order of magnitudes and various selected microfluidic phenomena and devices. The book grew out of a set of well-tested lecture notes. It is with its many pedagogical exercises designed as a textbook for an advanced undergraduate or first-year graduate course. It is also well suited for self-study.
Download or read book Integrated Nano Biomechanics written by Takami Yamaguchi and published by William Andrew. This book was released on 2018-06-27 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production. This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases. - Provides knowledge of integrated biomechanics, focusing on nano-scale, in this rapidly growing research field - Explains how the different technologies can be integrated and applied in a variety of biomedical application fields, as well as for alternative energy sources - Uses a collaborative, multidisciplinary approach to provide a comprehensive coverage of nano-biomechanics
Download or read book Optical Rheometry of Complex Fluids written by Gerald G. Fuller and published by Oxford University Press. This book was released on 1995-06-29 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a self-contained presentation of optical methods used to measure the structure and dynamics of complex fluids subject to the influence of external fields. Such fields--hydrodynamic, electric, and magnetic--are commonly encountered in both academic and industrial research, and can produce profound changes in the microscale properties of liquids comprised of polymers, colloids, liquid crystals, or surfactants. Starting with the basic Maxwell field equations, this book discusses the polarization properties of light, including Jones and Mueller calculus, and then covers the transmission, reflection, and scattering of light in anisotropic materials. Spectroscopic interactions with oriented systems such as absorptive dichroism, small wide angle light scattering, and Raman scattering are discussed. Applications of these methods to a wide range of problems in complex fluid dynamics and structure are presented, along with selected case studies chosen to elucidate the range of techniques and materials that can be studied. As the only book of its kind to present a self-contained description of optical methods used for the full range of complex fluids, this work will be special interest to a wide range of readers, including chemical engineers, physical chemists, physicists, polymer and colloid scientists, along with graduate and post-graduate researchers.
Download or read book Microfluidics written by Yu Song and published by John Wiley & Sons. This book was released on 2018-05-07 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book offering a global overview of fundamental microfluidics and the wide range of possible applications, for example, in chemistry, biology, and biomedical science. As such, it summarizes recent progress in microfluidics, including its origin and development, the theoretical fundamentals, and fabrication techniques for microfluidic devices. The book also comprehensively covers the fluid mechanics, physics and chemistry as well as applications in such different fields as detection and synthesis of inorganic and organic materials. A useful reference for non-specialists and a basic guideline for research scientists and technicians already active in this field or intending to work in microfluidics.
Download or read book Encyclopedia of Microfluidics and Nanofluidics written by Dongqing Li and published by Springer Science & Business Media. This book was released on 2008-08-06 with total page 2242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering all aspects of transport phenomena on the nano- and micro-scale, this encyclopedia features over 750 entries in three alphabetically-arranged volumes including the most up-to-date research, insights, and applied techniques across all areas. Coverage includes electrical double-layers, optofluidics, DNC lab-on-a-chip, nanosensors, and more.
Download or read book Chemical Engineering Fluid Mechanics written by Ron Darby and published by CRC Press. This book was released on 2016-11-30 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with the most current, accurate, and practical fluid mechanics related applications that the practicing BS level engineer needs today in the chemical and related industries, in addition to a fundamental understanding of these applications based upon sound fundamental basic scientific principles. The emphasis remains on problem solving, and the new edition includes many more examples.
Download or read book Microfluidics and Nanofluidics written by Mohsen Sheikholeslami Kandelousi and published by BoD – Books on Demand. This book was released on 2018-08-22 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the present book, various applications of microfluidics and nanofluidics are introduced. Microfluidics and nanofluidics span a broad array of disciplines including mechanical, materials, and electrical engineering, surface science, chemistry, physics and biology. Also, this book deals with transport and interactions of colloidal particles and biomolecules in microchannels, which have great importance to many microfluidic applications, such as drug delivery in life science, microchannel heat exchangers in electronic cooling, and food processing industry. Furthermore, this book focuses on a detailed description of the thermal transport behavior, challenges and implications that involve the development and use of HTFs under the influence of atomistic-scale structures and industrial applications.
Download or read book Micro Nano Devices for Blood Analysis written by Rui A. Lima and published by MDPI. This book was released on 2019-12-03 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of micro- and nanodevices for blood analysis is an interdisciplinary subject that demands the integration of several research fields, such as biotechnology, medicine, chemistry, informatics, optics, electronics, mechanics, and micro/nanotechnologies. Over the last few decades, there has been a notably fast development in the miniaturization of mechanical microdevices, later known as microelectromechanical systems (MEMS), which combine electrical and mechanical components at a microscale level. The integration of microflow and optical components in MEMS microdevices, as well as the development of micropumps and microvalves, have promoted the interest of several research fields dealing with fluid flow and transport phenomena happening in microscale devices. Microfluidic systems have many advantages over their macroscale counterparts, offering the ability to work with small sample volumes, providing good manipulation and control of samples, decreasing reaction times, and allowing parallel operations in one single step. As a consequence, microdevices offer great potential for the development of portable and point-of-care diagnostic devices, particularly for blood analysis. Moreover, the recent progress in nanotechnology has contributed to its increasing popularity, and has expanded the areas of application of microfluidic devices, including in the manipulation and analysis of flows on the scale of DNA, proteins, and nanoparticles (nanoflows). In this Special Issue, we invited contributions (original research papers, review articles, and brief communications) that focus on the latest advances and challenges in micro- and nanodevices for diagnostics and blood analysis, micro- and nanofluidics, technologies for flow visualization, MEMS, biochips, and lab-on-a-chip devices and their application to research and industry. We hope to provide an opportunity to the engineering and biomedical community to exchange knowledge and information and to bring together researchers who are interested in the general field of MEMS and micro/nanofluidics and, especially, in its applications to biomedical areas.
Download or read book Visualization and Simulation of Complex Flows in Biomedical Engineering written by Rui Lima and published by Springer Science & Business Media. This book was released on 2013-11-18 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the most recent advances in the application of visualization and simulation methods to understand the flow behavior of complex fluids used in biomedical engineering and other related fields. It shows the physiological flow behavior in large arteries, microcirculation, respiratory systems and in biomedical microdevices.
Download or read book Open Channel Microfluidics written by Jean Berthier and published by Morgan & Claypool Publishers. This book was released on 2019-09-04 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Open microfluidics, the study of microflows having a boundary with surrounding air, encompasses different aspects such as paper or thread-based microfluidics, droplet microfluidics and open-channel microfluidics. Open-channel microflow is a flow at the micro-scale, guided by solid structures, and having at least a free boundary (with air or vapor) other than the advancing meniscus. This book is devoted to the study of open-channel microfluidics which (contrary to paper or thread or droplet microfluidics) is still very sparsely documented, but bears many new applications in biology, biotechnology, medicine, material and space sciences. Capillarity being the principal force triggering an open microflow, the principles of capillarity are first recalled. The onset of open-channel microflow is next analyzed and the fundamental notion of generalized Cassie angle (the apparent contact angle which accounts for the presence of air) is presented. The theory of the dynamics of open-channel microflows is then developed, using the notion of averaged friction length which accounts for the presence of air along the boundaries of the flow domain. Different channel morphologies are studied and geometrical features such as valves and capillary pumps are examined. An introduction to two-phase open-channel microflows is also presented showing that immiscible plugs can be transported by an open-channel flow. Finally, a selection of interesting applications in the domains of space, materials, medicine and biology is presented, showing the potentialities of open-channel microfluidics.
