Download or read book Effect of Cevimeline on Oral Health and Quality of Life in Sjogren s Syndrome Patients written by Chiu-Man Katherine Leung and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Effect of Cevimeline on Oral Health and Quality of Life in Sjogren's Syndrome Patients" by Chiu-man, Katherine, Leung, 梁超敏, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract of thesis entitled Effect of Cevimeline on oral health and quality of life in Sjogren's syndrome patients submitted by LEUNG Chiu Man, Katherine for the degree of Doctor of Philosophy at The University of Hong Kong in October 2006 This thesis reports the results of two studies, 1) a cross-sectional study to investigate the oral health condition, oral microbial profile, saliva flow and health-related quality of life (HRQoL) of Sjogren's syndrome (SS) patients; and 2) a randomized double-blind, placebo-controlled crossover clinical trial (RCT) to assess the effect of cevimeline on oral health condition, oral microbial profile, saliva flow and HRQoL in SS patients. A total of 82 southern Chinese subjects participated in the cross-sectional study including primary SS (pSS), secondary SS (sSS) patients and non-SS subjects. Oral health condition, oral microbial profile and saliva flow were determined using verified clinical and laboratory techniques. HRQoL was evaluated using the SF-36, OHIP and a dry mouth questionnaire. Primary SS patients had a greater prevalence of oral candidiasis and xerostomic tongue changes (P Fifty southern Chinese SS patients entered and 44 completed the 24-week RCT. They were randomly assigned to receive cevimeline (30 mg three times per day) for 10 weeks (first arm) then stopped for 4 weeks (washout) before switching to take placebo for another 10 weeks (second arm) or receive placebo in the first arm and cevimeline in the second arm. Clinical oral examination, stimulated saliva flow measurement, oral microbial profile and HRQoL (XI, GOHAI, OSDI and SF-36) evaluation were carried out at baseline (week 0), after taking the first trial medication (week 10), after the washout period (week 14) and after taking the second trial medication (week 24). Patient satisfaction and preference were recorded after each trial medication (weeks 10 and 24). On taking cevimeline, there was a significant improvement of the GOHAI scores, as compared to placebo (P = 0.001). No significant differences were detected among other investigated parameters between cevimeline and placebo, except a reduction in the C. albicans level in plaque after cevimeline use. Cevimeline was effective in improving the OHRQoL and oral microbial profile of SS sufferers. However, it had no effects on oral health condition and saliva flow in SS sufferers. Patient preference and satisfaction were similar between cevimeline and placebo. Oral health condition, saliva flow and HRQoL were significantly impaired, and substantial alteration in the oral microbial profile was observed in southern Chinese SS patients. Cevimeline improved the OHRQoL and oral microbial profile of southern Chinese patients with SS, but it had no effect on general HRQoL, oral health condition and stimul

Download or read book Effect of Cevimeline on Oral Health and Quality of Life in Sj gren s Syndrome Patients written by Chiu-man Leung (Katherine) and published by . This book was released on 2006 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Effect of Cevimeline on Oral Health and Quality of Life in Sj gren s Syndrome Patients written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Dry Mouth The Malevolent Symptom written by Leo M. Sreebny and published by John Wiley & Sons. This book was released on 2010-02-25 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Xerostomia, more commonly called dry mouth, affects an estimated 20 percent of adults worldwide and can severely diminish one’s quality of life. Dry Mouth, the Malevolent Symptom: A Clinical Guide relies on evidence-based research to provide an introductory primer on oral dryness and the modalities available to treat it. The book describes the varied etiology of the disease, but emphasizes clinical protocols and step-by-step procedures for diagnosis and treatment planning. Dry Mouth is a user-friendly manual guiding clinicians through identifying and managing this common condition. Causes including radiotherapy, chemotherapy, systemic diseases, polypharmacy, and the natural progression of aging are discussed in conjunction with the clinical symptoms and signs associated with each one. Multiple avenues for treatment are presented, highlighting salivary stimulation and supplementation techniques, pharmacologic aids, and critically required oral therapy. Although intended primarily for the professionals that treat those affected by xerostomia, Dry Mouth may also be of interest to sufferers of this condition.

Download or read book Ocular Therapeutics written by Thomas Yorio and published by Academic Press. This book was released on 2011-04-28 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future.* Contains information that is vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics.* Provides not only information on current approaches to treatment, but also gives the reader a greater understanding as to what may become available for treating a number of important eye diseases.* Historical perspective for each of the topics as well as an important glimpse into the near future to develop an understanding of the new research directions underway.* New insight for drug delivery and for managing devastating diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States

Download or read book Oral Health in America written by and published by . This book was released on 2000 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Key Aspects of Comfort written by Sandra G. Funk and published by . This book was released on 1989 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Key Aspects books, each of which has won a Book-of-the-Year Award from the American Journal of Nursing, are designed to move the ideas and findings of nursing research into the practice setting. Each volume distills dozens of studies into a readable, jargon-free format with immediate relevance to nursing practice, and includes suggestions for implementation.

Download or read book Pharmacology and Therapeutics for Dentistry E Book written by John A. Yagiela and published by Elsevier Health Sciences. This book was released on 2010-03-12 with total page 957 pages. Available in PDF, EPUB and Kindle. Book excerpt: Use your knowledge of pharmacology to enhance oral care! Pharmacology and Therapeutics for Dentistry, 6th Edition describes how to evaluate a patient's health and optimize dental treatment by factoring in the drugs they take. It explores the basic fundamentals of pharmacology, special topics such as pain control, fear and anxiety, and oral complications of cancer therapy, and most importantly, the actions of specific drug groups on the human body. Whether you're concerned about the drugs a patient is already taking or the drugs you prescribe for treatment, this book helps you reduce risk and provide effective dental care. - An emphasis on the dental applications of pharmacology relates drugs to dental considerations in clinical practice. - Dental aspects of many drug classes are expanded to include antibiotics, analgesics, and anesthetics. - The Alternative Medicine in Dentistry chapter discusses chemicals used as alternative medicines and assesses their potential benefits and risks. - The Nonopioid Analgesics chapter groups together non-opioid analgesics, nonsterioidal anti-inflammatory drugs, and antirheumatic and antigout drugs, making these easier to locate and study. - Coverage of the endocrine system includes four separate chapters for the most comprehensive coverage. - Drug Interactions in Clinical Dentistry appendix lists potential interactions between drugs a patient is taking for nondental conditions and drugs that may be used or prescribed during dental treatment, including effects and recommendations. - Glossary of Abbreviations appendix includes the most common abbreviations used for drugs or conditions. - New Pharmacogenetics and Pharmacogenomics chapter covers the effects of genetic traits of patients on their responses to drugs. - A NEW introductory section offers tips for the study of dental pharmacology and relates pharmacology to dental considerations. - An updated discussion of drug-drug interactions covers the harmful effects of mixing medications. - Coverage of adverse effects and mechanisms of COX-2 inhibitors, antibiotic prophylaxis, and antiplaque agents explains the dental risks relating to common drug treatments.

Download or read book Dubois Lupus Erythematosus and Related Syndromes E Book written by Daniel J. Wallace and published by Elsevier Health Sciences. This book was released on 2018-08-16 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 50 years, Dubois' Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It's an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes. - Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. - Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients. - Offers an increased focus on the clinical management of related disorders such as Sjogren's syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS). - Presents the knowledge and expertise of more international contributors to provide new global perspectives on manifestations, diagnosis, and treatment. - Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, and more schematic diagrams throughout.

Download or read book Contemporary Oral Medicine written by Camile S. Farah and published by Springer. This book was released on 2019-03-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, written by world authorities in the field, is a comprehensive, up-to-date guide to the specialty of Oral Medicine, which is concerned with the diagnosis, prevention, and predominantly non-surgical management of medically related disorders and conditions affecting the oral and maxillofacial region. The pathophysiology, clinical presentation, diagnostic evaluation, and treatment of all relevant diseases and disorders are described with the aid of a wealth of clinical cases and illustrations that enable the reader to appreciate the diversity and potential complexity of Oral Medicine. In addition to the wide-ranging coverage of oral conditions, separate sections are devoted to bone and cutaneous pathology and to orofacial pain and its management, in addition to dental sleep medicine. The clinician who treats Oral Medicine patients will find this book to be an excellent aid to optimal management grounded in a sound knowledge of basic science and the dental and medical aspects of each disorder. In addition, it will serve as an outstanding textbook for undergraduate and postgraduate students.

Download or read book Neurorehabilitation Therapy and Therapeutics written by Krishnan Padmakumari Sivaraman Nair and published by Cambridge University Press. This book was released on 2018-10-11 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical handbook for clinicians covers pharmacological and non-pharmacological treatment options in neurological rehabilitation.

Download or read book Principles and Practice of Movement Disorders E Book written by Joseph Jankovic and published by Elsevier Health Sciences. This book was released on 2011-04-01 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Practice of Movement Disorders provides the complete, expert guidance you need to diagnose and manage these challenging conditions. Drs. Stanley Fahn, Joseph Jankovic and Mark Hallett explore all facets of these disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. An accompanying Expert Consult website makes the content fully searchable and contains several hundred video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses. Get just the information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Find the answers you need quickly and easily thanks to a reader-friendly full-color format, with plentiful diagrams, photographs, and tables. Apply the latest advances to diagnosis and treatment of pediatric movement disorders, Parkinson disease, and much more. View the characteristic presentation of each disorder with a complete collection of professional-quality, narrated videos online. Better visualize every concept with new full-color illustrations throughout. Search the complete text online, follow links to PubMed abstracts, and download all of the illustrations, at www.expertconsult.com.

Download or read book Dry Mouth written by Guy Carpenter and published by . This book was released on 2014-11-30 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Sjogren s Book written by Daniel J. Wallace MD and published by Oxford University Press. This book was released on 2011-10-03 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Afflicting one in seventy Americans, Sjögren's syndrome is an autoimmune disease that commonly causes dryness of the eyes, mouth, and nose, and that can lead to complications including profound fatigue, depression, and lymphoma. While there is no cure for Sjögren's, much can be done to alleviate the suffering of patients. This extensively revised handbook offers everything you need to know to cope with this disease. The Sjögren's Book, Fourth Edition is a comprehensive and authoritative guide, produced by the Sjögren's Syndrome Foundation and its medical advisors and edited by physician Daniel J. Wallace, a leading authority on autoimmune disorders. This expanded edition provides readers with the best medical and practical information on this disorder, bringing together the current thinking about Sjögren's in an easily readable and understandable book, with an entirely new section on lifestyle issues aimed at improving the quality of life for Sjögren's sufferers. With more than thirty chapters written by leading experts, the handbook illuminates the major clinical aspects of the syndrome and is loaded with practical tips and advice. Indeed, it offers a wide-ranging look at the many faces of Sjögren's, covering diagnosis, the various organ systems that can be affected, the possible psychological problems, and the many treatment options, as well as a concluding chapter listing the web, print, and media resources available. It is a valuable aid that patients can use while discussing their illness with their physician and an excellent resource for family members. And because Sjögren's is greatly underdiagnosed, this handbook is a particularly valuable resource for healthcare professionals. Recognized as the bible for Sjögren's suffers, this reliable and informative guide is the first place for patients to look when they have questions about this little known but serious chronic disease.

Download or read book Oral Complications of Cancer and Its Management written by Andrew Davies and published by Oxford University Press. This book was released on 2010-02-25 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral complications are hugely important for those treating cancer patients, either as an indication of disease or as a symptom of the disease. This is the first book to focus on this unique area of cancer care, providing international, evidence-based, clinical guidance for the whole team involved in treating the cancer patient with oral problems.

Download or read book Sj gren s Syndrome written by Robert I. Fox and published by Springer Science & Business Media. This book was released on 2011-09-15 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: The key knowledge assembled in this book comprises today’s most comprehensive resource on Sjögren’s syndrome. Sjögren’s patients require the care of a wide variety of clinical and surgical specialists to treat their disease and improve their quality of life. This volume presents a broad multi-disciplinary approach, enlisting the expertise of well-respected authors from around the world, covering the specialties of rheumatology, ophthalmology, oral medicine, oral surgery, otolaryngology, hematology, and others. This practical clinical resource begins with an overview of Sjögren’s myths, pearls and tips, information for referring physicians, and diagnostic and classification and criteria. The second section covers pathogenesis, providing the backbone for our understanding current diagnostics and therapeutics. The third section is devoted to clinical manifestations and therapeutic considerations. It covers the entire spectrum of symptoms and treatment, infused with the experience and astute clinical observations of the book’s contributors. With system-wide coverage of local and systemic therapy, the book examines current therapy, biologics, and emerging therapeutic targets. Presenting many international perspectives, this book creates an inter-connective conduit for the global community of Sjögren’s patients and physicians.

Download or read book Oxford Textbook of Palliative Medicine written by Geoffrey W. C. Hanks and published by Oxford University Press, USA. This book was released on 2011-07-21 with total page 1697 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasising the multi-disciplinary nature of palliative care, the fourth edition of this text also looks at the individual professional roles that contribute to the best-quality palliative care.