Download or read book Effect of Acute Exercise on Whole Body Fat Oxidation written by Marysa M. W. Smith and published by . This book was released on 2013 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: In consideration of the rising prevalence of obesity and its effect on metabolic health and disease, this study was conducted to examine mechanisms involved in adipose tissue function following an acute bout of exercise in abdominal subcutaneous adipose tissue. Sedentary, overweight/obese women (n=10, BMI=30.6+6.0 kg·m-2, VO2peak=30.3+5.4 m·Lkg-1·min-1)completed 2 visits to the lab in which they either exercised for 1 hour or a rested in bed for the equivalent time (control). Experiments were executed randomly using a randomized cross-over study design. Gas exchange measures were measured at three time points before biopsies and subcutaneous adipose biopsies were obtained pre-condition, immediately after condition (0hr), two hours post (2hr), and four hours post (4hr). Acute exercise had significant effects whole body fat oxidation and phosphorylation of insulin signalling proteins, but had no effect on the phosphorylation of proteins regulating the expression of glyceroneogenic genes. In combination, these results suggest that acute exercise can transiently decrease insulin signalling although the mechanism by which this occurs is unclear. Additionally, acute exercise had no effect on the phosphorylation of proteins that are thought to regulate glyceroneogenic gene expression, suggesting that there are either alternative mechanisms involved or that time since the consumption of a meal is a greater stimulus for the activation/upregulation of glyceroneogenesis. Our findings suggest that acute exercise may acutely alter function of adipose tissue such that it contributes to elevations in whole body fatty acid metabolism, however, whether or not chronic adaptations are induced remains an important area for future study.
Download or read book The Effects of Acute Exercise Recovery from Exercise and High Intensity Interval Training on Human Skeletal Muscle Membrane Fatty Acid Transport Proteins written by and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Possible Mechanisms to Explain Abdominal Fat Loss Effect of Exercise Training Other Than Fatty Acid Oxidation written by Chia-Hua Kuo and published by Frontiers Media SA. This book was released on 2022-01-07 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Effect of Acute and Chronic Exercise on Fat Oxidation and Hormonal and Plasma Metabolite Kinetics in Obese and Severely Obese Men written by Stefano Lanzi and published by . This book was released on 2014 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thèse. Biologie. Médecine. 2014
Download or read book Sport Nutrition written by Asker E. Jeukendrup and published by Human Kinetics Publishers. This book was released on 2009-12-31 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of "Sport Nutrition: An Introduction to Energy Production and Performance" presents the principles, background, and rationale for current nutrition guidelines specifically for athletes. Using a physiological basis, this text provides an in-depth look at the science behind sport nutrition. Students will come away with a comprehensive understanding of nutrition as it relates to sport and the influence of nutrition on exercise performance, training, and recovery. The chapters and the material within each chapter are sequenced in a logical order that will help instructors deliver a better course and spend less time in preparing lectures and tutorials. Instructors will also enjoy the completely new ancillaries with this edition, including an online instructor guide, test package, PowerPoint presentation package, and image bank. This text contains updated and expanded information to keep students current on the latest findings in sport nutrition: - A new chapter on training adaptations, including effects of nutrition on overtraining - New information on weight management and body composition for athletes - New research on carbohydrate and new recommendations for carbohydrate intake during training - An expanded discussion on the role of protein in strength and endurance exercise training - The latest information on exercise, nutrition, and immune function The new content complements the strong foundational information that the authors provided in the previous edition, including fuel sources for muscle and exercise metabolism, energy requirements for various sports, and a complete grounding in the macronutrients (carbohydrate, fat, and protein) and the micronutrients (vitamins and minerals). With more than 200 illustrations, new highlight boxes, and tables and sidebars throughout the text, students will be able to more easily grasp the scientific concepts presented in this text. Each chapter also includes learning objectives, key terms, and key points to help readers retain the information. The text presents not only nutrition principles but also the exercise biochemistry involved and the energy needs of athletes. Readers will better understand how supplements may be used in an athlete's diet, and they will learn how to separate fact from fallacy regarding the claims of the numerous nutritional supplements available today. More than a simple prescription of recommendations, this second edition of" Sport Nutrition" features a unique presentation that facilitates readers' understanding of the science supporting the nutrition recommendations. As a result, students will be prepared for advanced study and future careers, and professionals will gain the knowledge and confidence to provide sound advice to athletes.
Download or read book Physical Inactivity Does Not Impair the Insulin lowering Effects of Moderate intensity Exercise Yet it Does Impair Fat Metabolism written by Michael Dial and published by . This book was released on 2020 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute exercise and physical activity improve insulin sensitivity, glucose tolerance, and postprandial lipemia, although recent research suggests that physical inactivity may attenuate some of these healthy metabolic benefits of exercise. This study aimed to determine how two days of physical inactivity and physical activity affected exercise-induced changes in plasma insulin, glucose, and triglyceride concentrations during an oral glucose tolerance test (OGTT) performed the next morning. Five untrained men (n=2) and women (n=3) completed three five-day trails in a randomized crossover design. Each trial began with two days of normal activity levels, followed by two intervention days. Two days of physical inactivity (3,666 ± 100 steps) without exercise (SIT) were compared to two days of physical inactivity (3,077 ± 141 steps) with a 1-hr bout of moderate intensity cycling at 65% of VO2peak (SIT + EX). Finally, two intervention days of high activity (12,270 ± 408 steps) were performed with a 1-hour bout of moderate cycling (ACTIVE + EX). The following morning, subjects completed a 120-min OGTT, during which plasma was collected and analyzed for glucose, insulin, and triglycerides. No changes were observed in plasma glucose. Compared to SIT, insulin total area under the curve (AUCT) was 39% lower in SIT+EX (p=0.18) and 21% lower in ACTIVE+EX (p=0.48), demonstrating that exercise had an insulin-lowering effect. Plasma triglyceride AUCT in ACTIVE+EX was 26% lower than SIT (p=0.10) and 28% lower than SIT+EX (p=0.03), and fasting plasma triglyceride concentration in ACTIVE+EX was 34% lower than SIT (p=0.06) and 20% lower than SIT+EX (p=0.43). These data indicate that the insulin-lowering effect of physical activity is influenced to a greater extent by an acute bout of moderate exercise (65% VO2peak) than the background daily steps. Conversely, the triglyceride lowering effect of physical activity appears to be contingent upon higher physical activity (daily step count) and not acute moderate-intensity exercise. This also was the case with postprandial whole-body fat oxidation as ACTIVE+EX was 26% higher when compared to SIT+EX. Taken together, insulin sensitivity appears to be improved by prolonged moderate-intensity exercise (i.e. 65% of VO2peak), while postprandial triglyceride concentration and fat oxidation are improved by increasing daily step count (i.e.; from 4,000 to 11,000 per day)
Download or read book Sports Endocrinology written by F. Lanfranco and published by Karger Medical and Scientific Publishers. This book was released on 2016-06-28 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an up-to-date, extensive overview of the effects of physical activity and training on endocrine function. It gives insights into a complex relationship by describing effects with respect to exercise performance, growth, development, and ageing. It includes discussions of the endocrine response depending on exercise mode, intensity, and duration as well as on gender, age, and fitness level. Additionally the book deals with the impact of environmental and psychological factors on endocrine level. A substantial part of Sports Endocrinology is devoted to the 'hot topic' of hormonal doping in sports. The properties of androgens, growth hormone, erythropoietin, and dietary supplements are highlighted. The use and abuse among professional and recreational athletes is discussed and specific methods of detection are presented and explained. All contributors are well-known experts in sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection, so this book is a must-read for every professional involved in the field.
Download or read book The Effects of Prolonged Sitting and Acute Exercise on Postprandial Plasma Triglyceride Concentration written by Il-Young Kim and published by . This book was released on 2011 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: These studies investigated the effect of physical inactivity (prolonged sitting) and physical activity (walking, standing, and moderate intensity exercise) on postprandial plasma triglyceride concentration (PPTG). In the first study, we evaluated the effect of low intensity intermittent walking at ~25% VO2max (WALK) and energy-matched moderate intensity running at ~65% VO2max (RUN) on PPTG, compared to a sitting control (SIT). RUN reduced incremental area under the curves for plasma triglyceride concentration (TG AUC[subscript I]), compared to WALK by 17.3% (p = 0.04) and SIT by 27% (p [less than] 0.001). The reduced TG AUC[subscript I] in RUN was accompanied by enhanced whole body insulin sensitivity, compared to WALK and SIT (for both, p [less than] 0.05). Whole body postprandial fat oxidation at rest following a high fat test meal intake was enhanced in RUN by 31% (P [less than] 0.001) and to a lesser extent in WALK by 8.4% (p [less than] 0.005), compared to SIT. In the second study, we evaluated 1) the effect of 2 days of prolonged sitting on PPTG, and 2) the effect of 4 days of SIT on the ability of an acute bout of exercise to reduce PPTG, compared to the same days of active walking and standing with calorically balanced diet (WALK+B). To distinguish the effect of prolonged sitting from the excess calorie effect, we had a sitting condition with calorically balanced diet (SIT+B) in addition to a sitting condition with hypercaloric diet (SIT+H). Following 2 days of respective food and activity control, WALK+B was lower in TG AUC[subscript T] by 21.3% and AUC[subscript I] by 17.4%, compared to SIT+H (for both, p [less than] 0.005). WALK+B was lower than SIT+B for TG AUC[subscript T] by 17.7% (p = 0.165) and AUC[subscript I] by 23.5% (p = 0.145) although statistical significance was not achieved. Remarkably, an acute exercise following 4 days of either SIT+H or SIT+B failed to reduce both TG AUC[subscript T] and AUC[subscript I], compared to SIT+B in HFTT1. The same exercise following 4 days of WALK+B, however, reduced both TG AUC[subscript T] by 29% and TG AUC[subscript I] by 32% in HFTT2, compared to SIT+B in HFTT1 (for both, p [less than] 0.02). Further, both SIT conditions reduced relative whole body fat oxidation in favor of increases in carbohydrate oxidation, compared to WALK+B by more than 40% in both HFTT1 and HFTT2. Taken together, our data suggest that 1) exercise intensity plays an independent role with higher intensity being more effective than lower intensity exercise in reducing PPTG, and 2) prolonged sitting with excess energy intake amplifies PPTG and prolonged sitting impairs the ability of an acute bout of moderate intensity exercise to reduce PPTG. This emphasizes the importance of regular participation in moderate-to-vigorous intensity exercise and reducing sitting time by increasing non-exercise physical activities (i.e., walking and standing) for the favorable postprandial metabolic health from the individual and public health perspectives.
Download or read book Obesity written by Gareth Williams and published by John Wiley & Sons. This book was released on 2009-07-08 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive textbook addresses one of the major public health concerns of our era – obesity. Clearly and simply, Obesity: science to practice provides a balanced, coherent account of obesity: how to define and measure it, its epidemiology, the physiological basis, associated diseases, how to assess, manage and treat it, and also strategies for prevention. The book is generously illustrated, including graphs and flow charts for easy reference. The chapters cite key references so that interested readers may pursue a given topic in more detail. Well presented and thoroughly edited by one of the leading experts in the field, this is the textbook of choice for anyone working in obesity.
Download or read book THE EFFECT OF EXERCISE AND EXERCISE TRAINING ON FAT OXIDATION IN OLDER ADULTS written by Atcharaporn Limprasertkul and published by . This book was released on 2009 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: The population aged 65 and older in the United State is anticipated to increase by 53% by 2020. Aging is associated with changes in body composition and metabolism resulting in decreased maximal oxygen consumption (VO2max). In addition, gender, inactivity and diet in elderly may increase the risk of diseases such as cardiovascular disease, hypertension, and diabetes. Among the potential mechanisms associated with these changes may be reduced fat oxidation (FO). The immune system affects the factors described above, and in turn there are age-related changes in immune function which may lead to immunosenescence, thereby increasing the chance for infections and risks for some diseases. A common treatment for metabolic disturbances and immune function is statin drugs which decrease low density lipoprotein cholesterol (LDL-C) and reduce the risk of cardiovascular events and may reduce inflammatory processes.^The purpose of this dissertation was to determine if FO was reduced in elderly, specifically after correcting for other factors (e.g. diet, activity level, reduced VO2max etc.), and to investigate the impact FO has on immune responses to stress (exercise), and finally the benefits and consequences of statin therapy.Hypotheses: The following hypotheses were tested: 1) Elderly will have reduced fat oxidation, even after correction for the reduced maximal aerobic power, compared to young subjects. 2) The reduced fat oxidation in the elderly will be associated with reduced release and uptake of fats for metabolism, compared to young. 3) Aerobic exercise training in the elderly will improve fat oxidation, but will not reach the same level as the young. 4) Elderly will have an exaggerated immune response to exercise stress, which will be reduced by exercise training.^5) Statin therapy will significantly reduce fat oxidation.Protocol: To test these hypotheses, a series of studies were conducted. First, a retrospective analysis of total body fat oxidation from a randomized controlled study that was designed to test the effectiveness of an aerobic exercise program in elderly was completed. Second, a study was conducted to test total body fat oxidation, substrate delivery and immune responses to exercise in the elderly compared to young. In addition, an aerobic training program was conducted with the elderly to examine the total body fat oxidation, substrate delivery and immune response before and after training.^Third, compare elderly subjects on statin therapy with a matched control group for the above variables.Methods: In the first study, total body FO during progressive VO2max test on a cycle ergometer in sedentary young and elderly subjects was compared and then the effect of aerobic exercise training on FO in elderly determined. Healthy young women (n = 12), men (n = 10), elderly women (n = 44) and elderly men (n = 44) completed a VO2max test. Respiratory exchange ratio (RER = VCO2/ VO2) was measured as an estimate of FO. Elderly women and men (n =22 each) completed 8 weeks of aerobic exercise training (1 hr, 3 sessions/wk) on a cycle ergometer. For the second study, FO, VO2max, blood lipids, and the immune response to exercise in elderly (N=14) compared to young (n=16) and elderly prior to and after aerobic exercise training (12 wks, 3 sessions/wk for 1 hr).^VO2max and sustained submaximal (70% of VO2max) exercise tests were completed, as were pre and post-exercise blood samples. For the last study, elderly on statin therapy (n = 14) were compared to elderly control subjects (n = 14). FO was determined during maximal and sustained submaximal exercise protocol. Blood samples were drawn for lipid analysis and immune function.Results: VO2 and RER increased linearly with exercise intensity for young and elderly. RER was significantly higher in women than men (p = 0.001), in both young and elderly (p = 0.001). At submaximal VO2, RER increased as a function of VO2, and in elderly the slope increased significantly more than young (young men, RER = 0.12 VO2 + 0.71; elderly men, RER = 0.27 VO2 + 0.71; young women, RER = 0.33 VO2 + 0.54; elderly women, RER = 0.49 VO2 + 0.60, RER/L/min).^Exercise training in elderly increased VO2max (20% in elderly women, 30% in elderly men) and decreased RER at submaximal VO2 in elderly men (RER = 0.21 VO2 + 0.75), but not for elderly women. These data were confirmed in the second study where young had significantly higher VO2max than elderly (30.3 " 6.7 ml/min/kg vs. 16.7 " 6.2 ml/min/kg, p = 0.001). Young also had lower RER at all VO2's than elderly; however, not after correction for VO2max. Young had longer sustained exercise duration (45.5 " 17.6 min) than elderly pre-training (30.2 " 14.0 min). None of the differences between young and elderly could be accounted for by diet or daily activity levels. After 12 weeks of aerobic training in elderly, there was a significant increase in VO2max (14.53 " 3.68 to 24.54 " 4.57 ml/min/kg, p = 0.001).^After training, fasting total cholesterol (TC, 193 " 43 mg/dL) and low density lipoprotein cholesterol (118 " 34 mg/dL) did not change, while triglycerides (TG) (81 " 36 mg/dL to 115 " 59 mg/dL, p = 0.009) increased. After the VO2max test, post-training, RER (slope = 0.012 vs. 0.016, p = 0.001) and blood lactate (31%, p = 0.028) were significantly lower, while glucose increased (7%, p = 0.04). TG increased by the VO2max test (10-15%) both pre and post-training. After training, submaximal exercise time (58.3 " 27.3 min vs. 30.2 " 14.0 min, p = 0.02), glucose (20%, p = 0.038) and TG increased (6-18%, p = 0.024), while RER was reduced (0.90 " 0.03 vs. 1.00 " 0.03, p = 0.04). Although total caloric intake was higher in young, the balance of carbohydrates, fats and proteins was similar in young and elderly (about 53, 26 and 19%, respectively). In young subjects, no cytokines were increased after the VO2max test.^After the submaximal test in young, IL-1 & beta; (8 " 4 pg/ml) and IL-10 (0.7" 0.6 pg/ml) were not affected by exercise, while IL-6 increased significantly (1.9 " 1.3 to 2.9 " 2.2 pg/ml). In elderly after VO2max test, IL-1 & beta; increased (7.9 " 1.4 to 8.9 " 5.5 pg/ml, p = 0.05) and IL-10 decreased (0.6 " 1.1 to 0.8 " 1.5 pg/ml, p = 0.04). There were no differences between cytokines in young and elderly subjects (p = 0.38 to 0.63). For elderly there were no significant effects of exercise on IL-1 & beta;, IL-6 or IL-10 after 12 weeks of training. In the last study, RER was significantly higher in subjects taking statins during both the VO2max and submaximal tests, indicating reduced FO. Blood lipoprotein levels during exercise were not affected by statins nor were levels of glucose, lactate, or TG. However, free fatty acid levels were significantly elevated by exercise. Statin therapy did not affect IL-1 & beta; or TNF- & alpha;, but increased IL-6.^Conclusions: FO was reduced in the elderly before training, and remained lower than young even after VO2max and FO were increased after training, particularly in women. Elderly did not have reduced fat availability from blood or FO after correction for VO2max during exercise on a treadmill, which increased after training; and sustained exercise duration increased; however this 12 week aerobic training had little effect on the cardiovascular risk factors measured in this study. Neither young nor elderly healthy untrained subjects demonstrated inflammatory responses to exercise and training. In addition, cytokine production was not significantly altered in elderly. It appears that factors other than age may negatively impact the immune system in elderly subjects, i.e. diet, inactivity, diseases, etc.^Although statin therapy lowers baseline blood lipoproteins, its secondary effects need further consideration as FO was significantly reduced in elderly, and this could not be accounted for by diet, exercise, fitness or availability of fat from the blood.
Download or read book Whole body Electromyostimulation A Training Technology to Improve Health and Performance in Humans written by Wolfgang Kemmler and published by Frontiers Media SA. This book was released on 2020-07-08 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Antioxidants in Sport Nutrition written by Manfred Lamprecht and published by CRC Press. This book was released on 2014-09-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Download or read book The Biology of Exercise written by Michael J. Joyner and published by Perspectives Cshl. This book was released on 2017 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exercise training provokes widespread transformations in the human body, requiring coordinated changes in muscle composition, blood flow, neuronal and hormonal signaling, and metabolism. These changes enhance physical performance, improve mental health, and delay the onset of aging and disease. Understanding the molecular basis of these changes is therefore important for optimizing athletic ability and for developing drugs that elicit therapeutic effects. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines the biological basis of exercise from the molecular to the systemic levels. Contributors discuss how transcriptional regulation, cytokine and hormonal signaling, glucose metabolism, epigenetic modifications, microRNA profiles, and mitochondrial and ribosomal functions are altered in response to exercise training, leading to improved skeletal muscle, hippocampal, and cardiovascular function. Cross talk among the pathways underlying tissue-specific and systemic responses to exercise is also considered. The authors also discuss how the understanding of such molecular mechanisms may lead to the development of drugs that mitigate aging and disease. This volume will therefore serve as a vital reference for all involved in the fields of sports science and medicine, as well as anyone seeking to understand the molecular mechanisms by which exercise promotes whole-body health.
Download or read book Exercise Metabolism written by Mark Hargreaves and published by Human Kinetics. This book was released on 2006 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive reference for biochemists, sport nutritionists, exercise physiologists, and graduate students in those disciplines. Provides information on the metabolic processes that take place during exercise, examining in depth the mobilization and utilization of substrates during physical activity. Focuses primarily on the skeletal muscle, but also discusses the roles of the liver and adipose tissue. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Mitochondria in Obesity and Type 2 Diabetes written by Beatrice Morio and published by Academic Press. This book was released on 2019-04-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers. Synthesizes actual knowledge on mitochondrial function Provides an integrated vision of each tissue in the etiology of obesity and type 2 diabetes Identifies the interactive networks that involve alteration in mitochondrial mass and function in disease progression Highlights the role played by mitochondria in the prevention and treatment of obesity and type 2 diabetes
Download or read book The Effects of 10 Days of Endurance Exercise Training on Whole Body Fat Oxidation in Lean and Obese Women written by Melissa Anne Reed and published by . This book was released on 2006 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hormones Metabolism and the Benefits of Exercise written by Bruce Spiegelman and published by Springer. This book was released on 2018-03-07 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
