Download or read book Biological Safety written by Dawn P. Wooley and published by John Wiley & Sons. This book was released on 2020-07-02 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk—no matter how small—must be considered, assessed, and properly mitigated. If the science isn't safe, it isn't good. Now in its fifth edition, Biological safety: Principles and Practices remains the most comprehensive biosafety reference. Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom. Specifically, Biological Safety covers protection and control elements—from biosafety level cabinets and personal protection systems to strategies and decontamination methods administrative concerns in biorisk management, including regulations, guidelines, and compliance various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.

Download or read book Biology And Pathogenesis Of Rhabdo And Filoviruses written by Asit K Pattnaik and published by World Scientific. This book was released on 2014-12-30 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rhabdoviruses and Filoviruses are single-stranded, non-segmented, negative-strand RNA viruses, many of which cause significant morbidity and mortality in humans and animals. Certain members of these virus families have been used as excellent model systems to understand the molecular biology of replication, host responses to infections, and viral countermeasures. Rhabdoviruses have also been used as vaccine vectors as well as oncolytic agents.Studies on Filoviruses have now provided significant insights into how they enter susceptible cells, replicate and cause disease, and also how they evade the host's immune mechanisms. This book addresses the most recent findings on Rhabdovirus and Filovirus structure, replication mechanisms, host cell responses to virus infections and viral countermeasures. Chapters on emerging viruses as well as approaches for therapeutic interventions have also been included.This book represents an authoritative text that brings together the most recent advances on the cellular and molecular biology of Rhabdo- and Filoviruses, including mechanisms of pathogenesis.

Download or read book Gene Therapy for Viral Infections written by Patrick Arbuthnot and published by Academic Press. This book was released on 2015-06-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. - Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections - Bridges the gap between the basic science and the important medical applications of this technology - Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering - Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs - Arms the reader with the cutting-edge information needed to stay abreast of this developing field

Download or read book Hot Topics in Infection and Immunity in Children III written by Andrew J. Pollard and published by Springer Science & Business Media. This book was released on 2006-10-31 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers topics in infectious diseases in children and is intended for Pediatric Infectious Disease trainees, trainers, and all those who manage children with infections. There is a balance of clinical basic science. In response to numerous requests, additional tropical topics are covered in some depth. As in previous volumes, the emphasis is on hot topics of clinical relevance delivered by world class speakers.

Download or read book Viral Hemorrhagic Fevers written by Sunit K. Singh and published by CRC Press. This book was released on 2016-04-19 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral hemorrhagic fevers have captured the imagination of the public and made their way into popular books and movies by virtue of their extreme virulence and mysterious origins. Since 2001, concerns have grown about the potential use of many hemorrhagic fever viruses as biological weapons. This has led to a resurgence in research to develop improv

Download or read book Threat of Infection written by Jörg Hacker and published by . This book was released on 2005 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The proceedings give insights into the host-pathogen-interaction, the evolution of pathogens as well as the action of virulence factors and toxins. On the molecular level mechanisms of genome flexibility of various pathogens and the RNA interference strategies will be presented. Aspects concerning the pathogen reservoir, the transmission of infectious agents and novel detection methods will be discussed as well as preventive and therapeutic approaches. Moreover, the proceedings also cover the political and social aspects of infectious diseases from the past to the future.

Download or read book Terrorism and Critical Care written by Richard W. Carlson and published by . This book was released on 2005 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Intensive Care Unit (ICU) is an essential component of current medical systems, with the sickest patients from the Emergency Room and Operating Room transferred there for ongoing care. In addition to the ICU and Critical Care Unit (CCU), critical care services are provided in multiple areas of the hospital (e.g., emergency department, in-patient wards) and outside of the hospital (e.g., ground or air ambulance during patient transfers). This issue reviews the main issues involved in the administration of critical care services outside of designated CCU and ICU areas with the aim of improving patient outcomes.

Download or read book Handbook of Dendritic Cells written by Manfred B. Lutz and published by . This book was released on 2006 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive handbook on dendritic cells, featuring an introduction by Ralph M. Steinman and written by top experts. In three volumes, it covers all aspects from molecular cell biology to clinical applications, highlighting the role of dendritic cells in fighting cancer, virus infections, and autoimmune diseases.

Download or read book Virus Expression Vectors written by Kathleen L. Hefferon and published by . This book was released on 2007 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The specific mechanisms involved in the replication and gene expression of a number of viruses have been under investigation for many years. At present, significant breakthroughs to the field of virology in general have led to a more complete understanding of virus replication as well as the interactions between viruses and their hosts during the infection process. One of the more recent and prominent outcomes of this accumulation of knowledge has been the ability of viruses from many origins to be engineered and developed for use as expression vectors. Virus expression vectors can be developed for a wide variety of purposes ranging from gene therapy delivery systems to vaccine production systems or even to novel protein production systems for applications in industry. This book contains the accumulative effort of an array of leading international scientists who have worked toward developing virus expression vectors for these and other purposes. The development of animal, plant and insect viruses as expression vector systems has been included. Each chapter contains a literature review and highlights more recent developments within the authors' laboratories with respect to areas such as research in virus vector development, virus replication, or specific virus-host cell interactions. A number of these studies have now left the laboratory bench and are at the stage of preliminary clinical trials or, as in the case of plant virus expression vectors, field trials. This book is dedicated to my father Dennis C. Hefferon, who is a lawyer and academic, not a virologist, but nonetheless provided the inspiration for creating Virus Expression Vectors.

Download or read book Encyclopedia of Virology D H written by and published by . This book was released on 2008 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reference source that deals with the research in virology. It covers biological, molecular, and medical topics concerning viruses in animals, plants, bacteria and insects. It also offers coverage on AIDS and HIV, viral immunology and vaccines, and the origin, history, evolution and phylogeny of viruses. "Encyclopedia of Virology, Third Edition" continues its success as the largest single reference source of current research in virology. Unique in its use of concise 'mini-review' articles, this praised work covers biological, molecular, and medical topics concerning viruses in animals, plants, bacteria and insects. Now in five volumes, this new edition has been extensively revised and updated to reflect the 50 per cent increase in identified and accepted viruses since the year 2000. With over 25 per cent new chapters and over 1000 illustrations, this edition takes into account the new developments in virology research by including information on new emerging diseases such as avian flu, SARS and West Nile and the ability of some viruses to be used as agents of bioterrorism. Edited by leading Virologists Mahy and van Regenmortel, this third edition remains the number one all-inclusive source of information for virology researchers, students, and reference departments of academic, medical, and corporate libraries. This title offers extensive coverage on AIDS and HIV, viral immunology and vaccines, the economic importance and control of virus diseases, and the origin, history, evolution and phylogeny of viruses. It features: four color throughout; sections on future perspectives that show the direction of current research; 25 per cent articles; glossary of key terms for easy referencing; information on viruses of human clinical interest, including the virus causing SARS; more than 20 per cent virus classifications. It offers the most recent information from the 8th International Committee on Taxonomy and Classification of Viruses. It includes recommendations for further reading and a list of other relevant entries.

Download or read book A Current Bibliography on African Affairs written by and published by . This book was released on 2004 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Rasputin Effect When Commensals and Symbionts Become Parasitic written by Christon J. Hurst and published by Springer. This book was released on 2016-07-05 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on those instances when benign and even beneficial relationships between microbes and their hosts opportunistically change and become detrimental toward the host. It examines the triggering events which can factor into these changes, such as reduction in the host’s capacity for mounting an effective defensive response due to nutritional deprivation, coinfections and seemingly subtle environmental influences like the amounts of sunlight, temperature, and either water or air quality. The effects of environmental changes can be compounded when they necessitate a physical relocation of species, in turn changing the probability of encounter between microbe and host. The change also can result when pathogens, including virus species, either have modified the opportunist or attacked the host’s protective natural microflora. The authors discuss these opportunistic interactions and assess their outcomes in both aquatic as well as terrestrial ecosystems, highlighting the impact on plant, invertebrate and vertebrate hosts.

Download or read book Hot Topics in Infection and Immunity in Children written by Andrew J. Pollard and published by Springer Science & Business Media. This book was released on 2004-06-24 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hot Topics in Infection and Immunity in Children brings together leading experts in the field to provide a current and authoritative view concerning the hottest topics of concern to clinicians caring for children with infections and research scientists working in the areas of infectious disease, immunology, microbiology and public health. The book is based on a collection of manuscripts from a faculty of authors of international standing who contributed to a course in Paediatric Infection and Immunity in Oxford, UK in June 2003.

Download or read book Ebola and Marburg Viruses written by Hans-Dieter Klenk and published by Garland Science. This book was released on 2004 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.

Download or read book Jeffcoate s Principles of Gynaecology written by Narendra Malhotra and published by JP Medical Ltd. This book was released on 2018-08-16 with total page 1234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a complete guide to the diagnosis and management of gynaecological diseases and disorders for trainees in the field. Beginning with an overview of anatomy and physiology, and the functions of different parts of the gynaecological system, the following sections cover numerous disorders and their treatment. Several chapters are dedicated to ultrasound and robotics in gynaecology. This ninth edition has been fully revised and includes many new topics to provide trainees with the latest information and advances in the field. Authored by recognised experts, the comprehensive text is further enhanced by clinical photographs, diagrams, flowcharts and tables to assist learning. Key points Comprehensive guide to diagnosis and management of gynaecological disorders Fully revised, ninth edition featuring many new topics Highly illustrated with clinical photographs, diagrams, flowcharts and tables Previous edition (9789351521495) published in 2014

Download or read book The Arenaviridae written by Maria S. Salvato and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, a distinguished international group of contributors present the latest molecular, organismal, and epidemiological research on arenaviruses. Their work will broaden both the clinician's and the researcher's knowledge of basic mechanisms of immunological tolerance, viral immunosuppression, the nature of protective immune responses to vaccination, and viral effects on cell functions.

Download or read book Textbook of Pathology written by BN. Datta and published by Jaypee Brothers Publishers. This book was released on 2004 with total page 1162 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition has collected and presents considerable advances in medical science specially in the field of basic molecular biology. The knowledge has been updated and mistakes have been eliminated.