Download or read book Breast Cancer Metastasis and Drug Resistance written by Aamir Ahmad and published by Springer Nature. This book was released on 2019-08-27 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

Download or read book Mammography and Beyond written by National Research Council and published by National Academies Press. This book was released on 2001-07-23 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year more than 180,000 new cases of breast cancer are diagnosed in women in the U.S. If cancer is detected when small and local, treatment options are less dangerous, intrusive, and costly-and more likely to lead to a cure. Yet those simple facts belie the complexity of developing and disseminating acceptable techniques for breast cancer diagnosis. Even the most exciting new technologies remain clouded with uncertainty. Mammography and Beyond provides a comprehensive and up-to-date perspective on the state of breast cancer screening and diagnosis and recommends steps for developing the most reliable breast cancer detection methods possible. This book reviews the dramatic expansion of breast cancer awareness and screening, examining the capabilities and limitations of current and emerging technologies for breast cancer detection and their effectiveness at actually reducing deaths. The committee discusses issues including national policy toward breast cancer detection, roles of public and private agencies, problems in determining the success of a technique, availability of detection methods to specific populations of women, women's experience during the detection process, cost-benefit analyses, and more. Examining current practices and specifying research and other needs, Mammography and Beyond will be an indispensable resource to policy makers, public health officials, medical practitioners, researchers, women's health advocates, and concerned women and their families.

Download or read book Women and Health written by Marlene B. Goldman and published by Academic Press. This book was released on 2012-12-31 with total page 1616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Women and Health is a comprehensive reference that addresses health issues affecting women of all ages — from adolescence through maturity. It goes far beyond other books on this topic, which concentrate only on reproductive health, and has a truly international perspective. It covers key issues ranging from osteoporosis to breast cancer and other cancers, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease and other chronic illnesses, substance abuse, and societal and behavioral influences on health. In this second edition of Women and Health, chapters thoughtfully explore the current state of women's health and health care, including the influences of sex and gender on the occurrence of a wide variety of diseases and conditions. All chapters have been extensively updated and emphasize the epidemiology of the condition — the etiology, occurrence, primary and secondary prevention (screening), risk factors, surveillance, changing trends over time, and critical analysis of the diagnostic and treatment options and controversies. Treatment sections in each chapter have been expanded to create a stronger dialogue between epidemiologists and women's health practitioners. - Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of women's health issues, as opposed to searching through thousands of journal articles - Provides a common language for epidemiologists, public health practitioners, and women's health specialists to discuss the behavioral, cultural, and biological determinants of women's health - Researchers and medical specialists will learn how the gender-specific risks and features of one organ system's diseases affect the health of other organ systems - For example: Hormone replacement therapy used to treat imbalance within the endocrine system is also being used to prevent and treat cardiovascular disease; Drugs developed for type 2 diabetes are now being used in chemoprevention - Orients the non-gerontologist about the importance of considering the entire life cycle of women within research designs and treatment plans - Professors teaching courses in women's health will use slides and additional materials to structure lectures/courses; students will use slides as a unique resource to study for exams

Download or read book Textbook of Cancer Epidemiology written by Hans-Olov Adami and published by Oxford University Press. This book was released on 2008-02-27 with total page 783 pages. Available in PDF, EPUB and Kindle. Book excerpt: This superb text gives a concise, systematic account of what is currently known about the epidemiology and primary prevention for most forms of human cancer. Part 1 provides an introduction to basic concepts in epidemiology, a description of the global burden of cancer, definitions and characterizations of the various measures used, and approaches used to reveal genetic determinants of cancer risk and integrate biologic markers in the epidemiogic research process. Part 2 contains chapters of uniform structure on over 20 types of cancer, providing clinical and pathological outlines, descriptive epidemiology, and a comprehensive account of risk factors and their etiological importance. Specific sections address somatic and germ cell mutations that play a role in the occurrence of particular forms of cancer.

Download or read book Nutritional Oncology written by George L. Blackburn and published by Elsevier. This book was released on 2011-05-02 with total page 847 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutritional oncology is an increasingly active interdisciplinary field where cancer is investigated as both a systemic and local disease originating with the changes in the genome and progressing through a multi-step process which may be influenced at many points in its natural history by nutritional factors that could impact the prevention of cancer, the quality of life of cancer patients, and the risk of cancer recurrence in the rapidly increasing population of cancer survivors.Since the first edition of this book was published in 1999, the idea that there is a single gene pathway or single drug will provide a cure for cancer has given way to the general view that dietary/environmental factors impact the progression of genetic and cellular changes in common forms of cancer. This broad concept can now be investigated within a basic and clinical research context for specific types of cancer. This book attempts to cover the current available knowledge in this new field of nutritional oncology written by invited experts. This book attempts to provide not only the theoretical and research basis for nutritional oncology, but will offer the medical oncologist and other members of multidisciplinary groups treating cancer patients practical information on nutrition assessment and nutritional regimens, including micronutrient and phytochemical supplementation. The editors hope that this volume will stimulate increased research, education and patient application of the principles of nutritional oncology.NEW TO THIS EDITION:* Covers hot new topics of nutrigenomics and nutrigenetics in cancer cell growth * Includes new chapters on metabolic networks in cancer cell growth, nutrigenetics and nutrigenomics* Presents substantially revised chapters on breast cancer and nutrition, prostate cancer and nutrition, and colon cancer and nutrition* Includes new illustrations throughout the text, especially in the breast cancer chapter* Includes integrated insights into the unanswered questions and clearly defined objectives of research in nutritional oncology * Offers practical guidelines for clinicians advising malnourished cancer patients and cancer survivors on diet, nutrition, and lifestyle * Provides information on the role of bioactive substances, dietary supplements, phytochemicals and botanicals in cancer prevention and treatment

Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.

Download or read book The Cancer Atlas written by Ahmedin Jemal and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas illustrates the latest available data on the cancer epidemic, showing causes, stages of development, and prevalence rates of different types of cancers by gender, income group, and region. It also examines the cost of the disease, both in terms of health care and commercial interests, and the steps being taken to curb the epidemic, from research and screening to cancer management programs and health education.

Download or read book The Genetics of Cancer written by B.A. Ponder and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Download or read book Fertility Tables for Birth Cohorts by Color written by Robert L. Heuser and published by . This book was released on 1976 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compilation of statistical tables on fertility for birth cohorts by color (incl. Black women, etc.), in the USA for the period 1917 to 1973.

Download or read book Oral Contraceptives and Breast Cancer written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: At least 10.7 million American women use oral contraceptives (OCs). The potential connection with breast cancer has caused concern among these OC users and uncertainty among many of their physicians. This new volume offers the most up-to-date information available on this critical topic. While the best available knowledge does not support any fundamental change in clinical practice with respect to the use of OCs, this book offers specific recommendations for more research to fully resolve the relationship between OCs and breast cancer. Noting consumer confusion, the volume includes a concise summary of benefits, risks, and other practical information for contraceptive users and their doctors. The volume presents current data on changes in patterns of OC use, differences in risk at different ages, the benefits of OCs, and more. Oral Contraceptives and Breast Cancer will be important reading for obstetricians/gynecologists and other health professionals, their patients who use OCs, contraceptive manufacturers, women's health advocates, policymakers, and researchers.

Download or read book Cancer facts for people over 50 written by and published by . This book was released on 2005 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Breast written by K. I. Bland and published by Saunders. This book was released on 2009 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering the most comprehensive, up-to-date information on the diagnosis and management of, and rehabilitation following, surgery for benign and malignant diseases of the breast, this surgical reference is now in a new edition available in both print and online for easy, convenient access to the absolute latest advances.

Download or read book Early Detection of Breast Cancer written by S. Brünner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormous expansion seen over the last decade in the mammo graphic detection of breast cancer lesions, especially the use of screen ing procedures for the early detection of clinically unsuspected tumors, has made it necessary to summarize the experience made by various centers in the world. The 2nd International Copenhagen Symposium on Detection of Breast Cancer afforded an opportunity of gathering scientists from all over the world to discuss the various problems of early breast cancer detection with special reference to screening procedures. This book forms a synthesis of the information presented by leading scientists from many of the world's mammo graphic centers, particularly those in Sweden and the USA. Hence, the reader will have the opportunity to study the outstanding work carried out by various institutes and centers of breast cancer screening. It is our sincere hope that a study of this volume will encourage other scientists to join in the work on screening procedures. S. Brunner B. Langfeldt P. E. Andersen Contents S. A. Feig: 1 Hypothetical Breast Cancer Risk from Mammography S. A. Feig: Benefits and Risks of Mammography 11 R. L. Egan and M. B. McSweeney: Multicentric Breast Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . 28 M. B. McSweeney and R. L. Egan: Breast Cancer in the Younger Patient: A Preliminary Report 36 M. B. McSweeney and R. L. Egan: Bilateral Breast Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . . . . ' 41 N. Bjurstam: The Radiographic Appearance of Normal and Metastatic Axillary Lymph Nodes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 M. Moskowitz, S. A. Feig, C. Cole-Beuglet, S. H.

Download or read book Risk Factors for Breast Cancer written by and published by Am Cncl on Science, Health. This book was released on with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Diagnosing and Treating Adult Cancers and Associated Impairments written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2021-11-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is the second leading cause of death among adults in the United States after heart disease. However, improvements in cancer treatment and earlier detection are leading to growing numbers of cancer survivors. As the number of cancer survivors grows, there is increased interest in how cancer and its treatments may affect a person's ability to work, whether the person has maintained employment throughout the treatment or is returning to work at a previous, current, or new place of employment. Cancer-related impairments and resulting functional limitations may or may not lead to disability as defined by the U.S. Social Security Administration (SSA), however, adults surviving cancer who are unable to work because of cancer-related impairments and functional limitations may apply for disability benefits from SSA. At the request of SSA, Diagnosing and Treating Adult Cancers and Associated Impairments provides background information on breast cancer, lung cancer, and selected other cancers to assist SSA in its review of the listing of impairments for disability assessments. This report addresses several specific topics, including determining the latest standards of care as well as new technologies for understanding disease processes, treatment modalities, and the effect of cancer on a person's health and functioning, in order to inform SSA's evaluation of disability claims for adults with cancer.

Download or read book Assess Your True Risk of Breast Cancer written by Patricia Kelly and published by Holt Paperbacks. This book was released on 2000-10-13 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to give women the tools they need to realistically assess their risk of getting breast cancer--and choose the best course of action Ask women what their number-one health fear is and most will not hesitate before answering "breast cancer." The recent proliferation of easily misunderstood and often contradictory statistics about breast cancer and its causes, however, is scaring many women who have only a small risk of contracting the disease. Assess Your True Risk of Breast Cancer is designed to help women evaluate what their risk really is and then determine what the next step should be based on that risk. Written by a leading expert in the field, the book discusses everything from studies on how age and family history relate to breast cancer risk, to those on hormone replacement therapy and breast cancer, enabling a woman to understand and focus on her own personal situation. Whether providing advice on how to get more extensive testing, counseling, and preventative measures when necessary, or offering the welcome assurance that the risk is small enough to warrant just annual checkups, mammograms, and regular self-examinations, Assess Your True Risk of Breast Cancer replaces rumors and scare tactics with solid, practical, and vital information.

Download or read book Early Life Origins of Human Health and Disease written by John P. Newnham and published by Karger Medical and Scientific Publishers. This book was released on 2009-01-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is compelling evidence that many of the risks leading to the most frequent chronic diseases in adulthood originate in the earliest stages of life. Adverse environmental conditions in utero and during infancy can lead to negative health effects during the subsequent lifetime of the exposed individual.This book offers precious insights into the latest concepts and results from epidemiologic, clinical and basic studies in this burgeoning area of health care. The developmental origins of various diseases such as diabetes, obesity and cancer are examined, as well as the early programming of reproductive health and different organs. Attention is given to the impact of environmental factors such as nutrition and pollution, and the mediating genetic and epigenetic pathways are reviewed. A crucial point under discussion is the concept of environmental insults adversely affecting not only the exposed persons, but also their descendants. In addition, the economic consequences of a suboptimal start to life and the importance of preventive measures are stressed.This publication is of great value to anyone interested in health care, notably to specialists in obstetrics, pediatrics, internal medicine, obesity, diabetes and heart disease.