Download or read book Immunopharmacology of the Gastrointestinal System written by John L. Wallace and published by Academic Press. This book was released on 1993-03-01 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diseases of the digestive system have a higher morbidity rate than any other group of disorder. There is a growing body of evidence that the immune system participates in the pathogenesis of a wide range of these diseases, including peptic ulcer disease and the gastropathy induced by nonsteroidal anti-inflammatory drugs (NSAIDS). For these reasons, efforts to develop novel therapies for digestive diseases are increasingly focused on the immune system. This volume reviews the immunopharmacology of the gastrointestinal tract at four distinct levels: Immunomodulation at a cellular level Cellular targers for immunomodulating drugs Specific classes of inflammatory mediators Utility and mechanisms of action of glucocorticoids in the treatment of diseases of the gastrointestinal tract.

Download or read book Navigating the Technological Tide The Evolution and Challenges of Business Model Innovation written by Bahaaeddin Alareeni and published by Springer Nature. This book was released on with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mediators of the Allergic State written by and published by Ardent Media. This book was released on 1972 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Diabetic Foot written by Aristidis Veves and published by Springer. This book was released on 2018-09-05 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the fourth edition of this gold-standard title, a distinguished panel of experts provides a thorough update of the significant improvements in our understanding of diabetic foot physiology and its clinical management. Divided into three sections, the first part focuses on clinical features and diagnosis; the second on pathophysiology; and the third on the management of diabetic foot problems. In addition to updating all previous chapters, several new contributions have been added, reflecting advances in our understanding of the causes of diabetic foot ulcers and efforts to develop new and more effective therapies. The authors, many practicing at the famous Joslin-Beth Israel Deaconess Foot Center, again illuminate the successful new multidisciplinary approach now clearly required for successful treatment of the diabetic foot. Drawing on the experiences of diabetologists, podiatrists, vascular surgeons, infectious disease specialists, orthotists, plastic and orthopedic surgeons, The Diabetic Foot: Medical and Surgical Management, 4th Edition expertly describes standard techniques and current methods derived from the most recent data. This updated edition will be of significant value to all physicians and researchers with interest in a state-of-the-art understanding of the diabetic foot.

Download or read book Targeting of Drugs written by Gregory Gregoriadis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Successful drug use in biology and medicine is often prejudiced by the failure of drugs that are otherwise active in vitro to act as efficiently in vivo. This is because in the living animal drugs must, as a rule, bypass or traverse organs, membranes, cells and molecules that stand between the site of administration and the site of action. In practice, however, drugs can be toxic to normal tissues, have limited or no access to the target and be prematurely excreted or inactivated. There is now growing optimism that such problems may be resolved by the use of carrier systems that will not only protect the non-target environment from the drugs they carry but also deliver them to where they are needed or facilitate their release there. Carrier systems presently under investigation include antibodies, glycoproteins, cells, reconstituted viruses and liposomes. Recent advances in the chemistry of cell receptor and receptor-recognising molecules, llnmunology, and natural and artificial membranes have revealed a multitude of ways in which such carrier systems can be modified or improved upon.

Download or read book Issues in Chemistry and General Chemical Research 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 10508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Chemistry and General Chemical Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Chemistry and General Chemical Research. The editors have built Issues in Chemistry and General Chemical Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chemistry and General Chemical Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Chemistry and General Chemical Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Thrombosis and Cardiovascular Diseases written by A. Strano and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Four years ago when the first European Symposium on the re lationship between alterations of blood clotting mechanisms and atherosclerosis was organized, we asked ourselves which would be the best way to obtain both scientific and practical contributions. We have been interested in cardiovascular diseases for several years now and have therefore focused our attention on the "container" (Le. the blood vessel) rather than on the "contents" (Le. the various components of blood) as considered only from a haemodynamic point of view. In recent years correlations were found between alterations of vascular wall and alteration of coagulative, fibrinolytic, and plate let factors as well as of haemorheological phenomena in the thrombo genic evolution of atherosclerotic lesions. A close cooperation between cardiologists and workers interested in atherosclerosis and thrombosis is therefore necessary. We think that the most appropriate approach to the various problems concerning correlations between thrombogenic and atherosclerotic lesions is co-operation between experts in these different fields of research. We thus decided to organize the 2nd Symposium taking into account the great progress achieved in this field during the past few years, and hope that discussions on diagnostic and therapeutical perspec' tives will yield useful elements both for the cardiologist and for the cardiologist and for the general practitioner.

Download or read book Pediatric Sports Medicine for the Practitioner written by O. Bar-Or and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Manuals in Pediatrics are designed to broaden the prac titioner's clinical scope by providing a wide range of diagnostic and management skills ordinarily considered to be the exclusive domain of the specialists. Although the series as a whole constitutes a comprehen sive text in pediatrics, each volume stands on its own as a self-contained the busy practitioner. reference for In order to maintain a uniform style and coverage of each subject, each manual is usually written by no more than one or two authors. Each author is an acknowledged expert in his or her field and provides a comprehensive, up-to-date account of the topic under discussion. Practi cally oriented, each volume offers concise guidelines and courses of treatment. Michael Katz E. Richard Stiehm Preface Much knowledge has been generated in recent years by scientists investigating the triad: child-exercise-health. Yet little of this infor mation is available in pediatric textbooks, for application by the clinician. This book is intended to bridge the resulting gap.

Download or read book The Pharmacology of Benzopyrone Derivatives and Related Compounds written by Miklós Gábor and published by . This book was released on 1986 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Liquid Crystals Volume 2B written by Dietrich Demus and published by John Wiley & Sons. This book was released on 2011-09-22 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Liquid Crystals is a unique compendium of knowledge on all aspects of liquid crystals. In over 2000 pages the Handbook provides detailed information on the basic principles of both low- and high-molecular weight materials, as well as the synthesis, characterization, modification, and applications (such as in computer displays or as structural materials) of all types of liquid crystals. The five editors of the Handbook are internationally renowned experts from both industry and academia and have drawn together over 70 leading figures in the field as authors. The four volumes of the Handbook are designed both to be used together or as stand-alone reference sources. Some users will require the whole set, others will be best served with one or two of the volumes. Volume 1 deals with the basic physical and chemical principles of liquid crystals, including structure-property relationships, nomenclature, phase behavior, characterization methods, and general synthesis and application strategies. As such this volume provides an excellent introduction to the field and a powerful learning and teaching tool for graduate students and above. Volumes 2A and 2B concentrate on low-molecular weight materials, for example those typically used in display technology. A high quality survey of the literature is provided along with full details of molecular design strategies, phase characterization and control, and applications development. These volumes are therefore by far the most detailed reference sources on these industrially very important materials, ideally suited for professionals in the field. Volume 3 concentrates on high-molecular weight, or polymeric, liquid crystals, some of which are found in structural applications and others occur as natural products of living systems. A high-quality literature survey is complemented by full detail of the synthesis, processing, analysis, and applications of all important materials classes. This volume is the most comprehensive reference source on these materials, and is therefore ideally suited for professionals in the field.

Download or read book Deutsche Pharmakologische Gesellschaft written by Deutsche Pharmakologische Gesellschaft and published by Springer. This book was released on 2013-12-19 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Current Research in Acupuncture written by Ying Xia and published by Springer Science & Business Media. This book was released on 2012-08-09 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by over 60 scientists and clincicians from the United States, mainland China, Germany, Australia, Japan, Sweden, Portugal and Hong Kong, Current Research in Acupuncture discusses recent advances in acupuncture research in a modern scientific language. The first 5 chapters investigate the basic mechanisms of acupuncture. Later chapters explore topics including acupuncture treatment and potential mechanisms for epilepsy, Parkinson’s diseases, neurodegenerative disorders such as Alzheimer’s disease, vascular cognitive impairment, aging, anxiety, polycystic ovary syndrome, pain, nerve root cervical spondylosis, stroke, imflamation, myocardial ischemia and other cardiovascular diseases. Following the translational and clinical discussions, 4 chapters present new prospects for acupuncture theories and applications. The final chapter comments on the pitfalls and problems of the previous studies and suggests direction for future research towards in-depth understanding of acupuncture, along with better application of acupuncture in modern medicine. Each chapter is written by one or more experts in the field. This unique book provides a broad perspective on the principles of acupuncture for acupuncture researchers and neuroscientists. The laboratory and clinical investigations of various acupoints and optimal conditions provide unique clues to acupuncturists for improved clinical efficacy. For a medical student, this book is a modern course in ancient Traditional Chinese Medicine, especially acupuncture. Ying Xia, the chief editor, is Professor and Vice-Chairman of the Department of Neurosurgery at The University of Texas Medical School in Houston, Texas, USA. Guanghong Ding is Professor in the Department of Mechanics and Engineering Science at Fudan University and Director of Shanghai Research Center for Acupuncture and Meridians, Shanghai, China. Gen-Cheng Wu is Professor of Neurobiology; Chairman, Department of Integrative Medicine and Neurobiology; Director, Institute of Acupuncture Research; and Director, WHO Collaborating Center for Traditional Medicine, at Shanghai Medical College of Fudan University, Shanghai, China.

Download or read book Principles and Practice of Ophthalmology E Book written by Daniel M. Albert and published by Elsevier Health Sciences. This book was released on 2008-02-27 with total page 5689 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inside the 3rd edition of this esteemed masterwork, hundreds of the most distinguished authorities from around the world provide today's best answers to every question that arises in your practice. They deliver in-depth guidance on new diagnostic approaches, operative technique, and treatment option, as well as cogent explanations of every new scientific concept and its clinical importance. With its new streamlined, more user-friendly, full-color format, this 3rd edition makes reference much faster, easier, and more versatile. More than ever, it's the source you need to efficiently and confidently overcome any clinical challenge you may face. Comprehensive, authoritative, and richly illustrated coverage of every scientific and clinical principle in ophthalmology ensures that you will always be able to find the guidance you need to diagnose and manage your patients' ocular problems and meet today's standards of care. Updates include completely new sections on "Refractive Surgery" and "Ethics and Professionalism"... an updated and expanded "Geneitcs" section... an updated "Retina" section featuring OCT imaging and new drug therapies for macular degeneration... and many other important new developments that affect your patient care. A streamlined format and a new, more user-friendly full-color design - with many at-a-glance summary tables, algorithms, boxes, diagrams, and thousands of phenomenal color illustrations - allows you to locate the assistance you need more rapidly than ever.

Download or read book Development of Anti Asthma Drugs written by Derek R. Buckle and published by Elsevier. This book was released on 2013-10-22 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of Anti-Asthma Drugs reviews existing asthma treatments and novel approaches currently under investigation, in the context of their mode of action and clinical effectiveness, in the hope that this might lead to a greater understanding of the factors involved in the expression of the disease and, therefore, in the design of better drugs. It is planned based on the concept of the causes and treatment of asthma, This book is organized in three main parts. Part I deals with the nature of asthma, its pathological mechanisms, natural history and epidemiology. Part II discusses mediators associated with asthma including platelet-activating factor, leukotrienes and histamine. Part II covers pharmaceutical approaches in the development of anti-asthma drugs and includes sections on inhibitors of mediator release and competitive and functional antagonists. This book will be of interest to persons dealing with studies on anti-asthma drugs and those interested in pharmacological development.

Download or read book Late Phase Allergic Reactions written by Walter Dorsch and published by CRC Press. This book was released on 1990-08-27 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important publication presents new information regarding "Late Phase Allergic (or Inflammatory) Reactions" (LPR). It includes present knowledge on the pathogenesis of LPR in human skin, nose, bronchi, and other organ systems. The book discusses the roles of antibodies, mediators, and cells as well as animal models of LPR. It describes the importance of LPR in the pathogenesis of chronic disease and the possibilities of their pharmacological modulation. The authors discuss clinical conclusions to be drawn from the observation of LPR, such as continuous treatment and immunotherapy. This volume is a useful reference for scientists and clinicians wishing to understand more about the problems of their allergic patients.

Download or read book The Japanese Journal of Pharmacology written by and published by . This book was released on 1993 with total page 1274 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Annual Reports in Medicinal Chemistry written by and published by Academic Press. This book was released on 1977-10-05 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annual Reports in Medicinal Chemistry