Download or read book Clarke s Analysis of Drugs and Poisons written by A. C. Moffat and published by . This book was released on 2004 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual and reference work provides a source of analytical data for drugs and related substances. It is intended for scientists faced with the difficult problem of identifying a drug in a pharmaceutical product, in a sample of tissue or body fluid, from a living patient or in post-mortem material. Volume One contains 32 chapters covering the practice of and analytical procedures used in forensic toxicology. Volume Two contains over 1750 drug and related substance monographs detailing: physical properties; analytical methods; pharmacokinetic data; and toxicity data, as well as expanded indexes and appendices. These volumes should be useful for all forensic and crime laboratories, toxicologists and analytical chemists, pathologists, poison information centres and clinical pharmacology departments.
Download or read book The Poisoner s Handbook written by Deborah Blum and published by Penguin. This book was released on 2011-01-25 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is "a vicious, page-turning story that reads more like Raymond Chandler than Madame Curie." —The New York Observer “The Poisoner’s Handbook breathes deadly life into the Roaring Twenties.” —Financial Times “Reads like science fiction, complete with suspense, mystery and foolhardy guys in lab coats tipping test tubes of mysterious chemicals into their own mouths.” —NPR: What We're Reading A fascinating Jazz Age tale of chemistry and detection, poison and murder, The Poisoner's Handbook is a page-turning account of a forgotten era. In early twentieth-century New York, poisons offered an easy path to the perfect crime. Science had no place in the Tammany Hall-controlled coroner's office, and corruption ran rampant. However, with the appointment of chief medical examiner Charles Norris in 1918, the poison game changed forever. Together with toxicologist Alexander Gettler, the duo set the justice system on fire with their trailblazing scientific detective work, triumphing over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice. In 2014, PBS's AMERICAN EXPERIENCE released a film based on The Poisoner's Handbook.
Download or read book Drugs Poisons and Chemistry Revised Edition written by Suzanne Bell and published by Infobase Holdings, Inc. This book was released on 2019-10-01 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic chemists and toxicologists work with drugs and poisons, but they each start with different evidence. Forensic chemists working in a crime lab must determine if the physical evidence they receive is an illegal substance such as marijuana or cocaine. They are also responsible for samples—including fire debris, soil, paint, glass, explosives, and fibers—obtained from suspected arson crimes. Toxicologists, on the other hand, work with biological evidence such as blood, saliva, urine, and feces, using analytical chemistry to identify chemical traces and unmetabolized drugs. They often work in labs associated with a medical examiner’s office or a hospital. Drugs, Poisons, and Chemistry, Revised Edition touches on all aspects of forensic chemistry, including how it developed and what it includes today. This useful eBook covers a short history of forensic chemistry, detailing the story of arsenic and those who developed effective tests to detect it. Delving into the tools and techniques used by forensic chemists—ranging from such familiar tools as the microscope to slightly more obscure tools as the use of antibodies to detect toxins—this comprehensive resource provides a thorough examination of these three main areas of forensic chemistry. Chapters include: History and Pioneers Scientific Principles, Instrumentation, and Equipment Toxicology: Drugs and Poisons in the Body Forensic Drug Analysis Conclusions: The Future of Drugs, Poisons, and Chemistry.
Download or read book The Art and Science of Poisons written by Olen R. Brown and published by Bentham Science Publishers. This book was released on 2018-06-04 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poisons, due to their lethal nature, invoke a sense of fear in humans. Yet, they have also impacted other aspects of human life. Poisons have been used by nomadic hunters to kill their prey, by scientists to explore complex biochemical mechanisms of the body, by physicians to lower cholesterol and to kill cancer cells, by farmers and the general public to destroy pests, by the evil minded for homicide, and by tyrants as weapons of war. The Art and Science of Poisons presents two facets of poisons: the science behind them and their place in history and art. The science of poisons describes their biochemistry and how they kill. The science story voyages into the sub-microscopic world of atoms, molecules, and cells. Only there can we see the true miracles and mysteries of life and death. Chapters in the book explore poisons from snakes, spiders, scorpions, sea creatures, as well as poisons made by humans in the laboratory, and those which are derived from beautiful plants. The art of poisons, on the other hand, encompasses everything else about these agents that conjures up the image of the skull and crossbones. This side of the story explores the legends and tales of intrigue and surreptitious deaths of well-known personalities such as Socrates, Cleopatra, Hitler, and many more. General readers with a curiosity about science and an interest in history and human nature will enjoy both facets presented in this brief, yet varied exploration into the world of poisons.
Download or read book A Forensic Casebook written by William J. Allender and published by . This book was released on 2014-08-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs and poisons from a variety of sources have been used illegally for centuries and most conjure up an unfortunate, enduring fascination. People appear to be both attracted by them and at the same time repelled by them, due to the fact that they are both deadly and, at the same time, can be very discreet. In forensic investigations, the questions that are usually raised are: "Did the victim overdose? "What was the poison/ drug used?" "Was it murder, an accident or suicide?" and "How was it taken and how much?" However, the difference may come down to how it was administered, to the probable dosage depending on the potency (a 'touch' maybe too much?), to the levels found in the body, to body weight and to the victim's tolerance, whether or not a regular user of the substance. Then there's always the motive for carrying out the deed.
Download or read book The Poison Paradox written by John Timbrell and published by Oxford University Press, USA. This book was released on 2005-06-23 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using reported disasters and everyday examples, this book examines both natural and man-made chemicals that we are exposed to. Illuminating the world of toxicology, it explains how they are toxic and the different reactions that individuals have to them. It also aims to debunk the popular belief that 'Natural is good, Man-made is bad'.
Download or read book Poisonous Plants and Phytochemicals in Drug Discovery written by Andrew G. Mtewa and published by John Wiley & Sons. This book was released on 2020-12-22 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career
Download or read book Clarke s Isolation and Identification of Drugs in Pharmaceuticals Body Fluids and Post mortem Material written by Eustace George Coverley Clarke and published by . This book was released on 1986 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the means to identify and quantify drugs and other toxic substances in situations of overdose or poisoning and to interpret analytical results. Includes an analysis of toxic metals and pesticides.
Download or read book Fundamentals of Analytical Toxicology written by Robert J. Flanagan and published by John Wiley & Sons. This book was released on 2008-03-03 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electrophoresis, mass spectrometry, and immunoassay – are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.” Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists “Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background “Boxes”. The many and up to date literature references in each chapter demonstrate the authors’ thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.” GTFCh Bulletin “Toxichem + Krimtech”, May 2008 (translated, original review in German) “Many toxicologists will add this important reference to their libraries because it competently fills a need ...” International Journal of Toxicology “The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.” International Journal of Environmental Analytical Chemistry
Download or read book The Poison Trials written by Alisha Rankin and published by University of Chicago Press. This book was released on 2021-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1524, Pope Clement VII gave two condemned criminals to his physician to test a promising new antidote. After each convict ate a marzipan cake poisoned with deadly aconite, one of them received the antidote, and lived—the other died in agony. In sixteenth-century Europe, this and more than a dozen other accounts of poison trials were committed to writing. Alisha Rankin tells their little-known story. At a time when poison was widely feared, the urgent need for effective cures provoked intense excitement about new drugs. As doctors created, performed, and evaluated poison trials, they devoted careful attention to method, wrote detailed experimental reports, and engaged with the problem of using human subjects for fatal tests. In reconstructing this history, Rankin reveals how the antidote trials generated extensive engagement with “experimental thinking” long before the great experimental boom of the seventeenth century and investigates how competition with lower-class healers spurred on this trend. The Poison Trials sheds welcome and timely light on the intertwined nature of medical innovations, professional rivalries, and political power.
Download or read book Alkaloids written by Shinji Funayama and published by Elsevier. This book was released on 2014-10-21 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alkaloids are a large group of structurally complex natural products displaying a wide range of biological activities. The purpose of Alkaloids: A Treasury of Poisons and Medicines is to classify, for the first time, the alkaloids isolated from the natural sources until now. The book classifies all of the alkaloids by their biosynthetic origins. Of interest to the organic chemistry and medicinal chemistry communities involved in drug discovery and development, this book describes many alkaloids isolated from the medicinal plants, including those used in Japanese Kampo medicine. - Classifies and lists alkaloids from natural sources - Occurrence and biosynthetic pathways of alkaloids - Indicates key uses and bioactivity of alkaloids
Download or read book All Medicines Are Poison written by Melvin H. Kirschner and published by AuthorHouse. This book was released on 2009 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, "All Medicines are Poison!," Melvin H. Kirschner, MPH, MD, sets out to remove the fog of confusion that clouds the landscape patients are required to navigate in their search for health care today. This book describes the risks and benefits associated with the use of medicines, and explores the validity of other treatment modalities referred to as "Complimentary and Alternative Medicine (CAM). He discusses the numerous failings and backroom dealings in the pharmaceutical and insurance industries, and highlights possible solutions to many of these current concerns. Dr. Kirschner has had an extensive career in the healthcare field. He has championed patient's rights throughout his career. As one of the key physicians instrumental in the enactment of the first biomedical ethical guidelines in the world, he has always strived for close doctor/patient relationships where the patient's concerns always come first.
Download or read book Medical Toxicology written by Pınar Erkekoglu and published by BoD – Books on Demand. This book was released on 2021-02-03 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical toxicology is a sub-branch of toxicology concerned with the diagnosis, management, and prevention of poisoning and other adverse effects of drugs, cosmetics, personal care products, occupational and environmental toxicants, and biological agents. Poisoning with drugs, herbs, venoms, and toxins is a significant global public health problem. Medical toxicologists are involved in the assessment and treatment of acute or chronic poisoning, substance abuse, adverse drug reactions, drug overdoses, envenomation, industrial accidents, and other chemical exposures. As such, there is a pressing need for safe and specific antidotes, as many antidotes currently in use have a relatively low margin of safety or therapeutic index. This book focuses on poisonings with drugs, venoms, toxins, interaction in clinics, antidotes, and forensics. It provides qualified scientific knowledge on different aspects of medical toxicology, drug and substance abuse, clinical interactions between drugs and herbs, antidotes, antidote networks, and forensic toxicology.
Download or read book Forensic Chemistry written by Suzanne Bell and published by CRC Press. This book was released on 2022-04-27 with total page 669 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic Chemistry, Third Edition, the new edition of this ground-breaking book, continues to serve as the leading forensic chemistry text on the market. Fully updated, this edition describes the latest advances in current forensic chemistry analysis and practice. New and expanded coverage includes rapid advances in forensic mass spectrometry, NMR, and novel psychoactive substances (NPSs). Topics related to seized drug analysis, toxicology, combustion and fire investigation, explosives, and firearms discharge residue are described and illustrated with case studies. The role of statistics, quality assurance/quality control, uncertainty, and metrology are integrated into all topics. More pharmacological and toxicokinetic calculations are presented and discussed. Hundreds of color figures, nearly 450 total, along with graphs, illustrations, worked example problems, and case descriptions are used to show how analytical chemistry is applied to forensic practice. Coverage offer students insight into the legal context in which forensic chemistry is conducted and introduces them to the sample types and sample matrices frequently encountered in forensic laboratories.
Download or read book Essentials of Pharmaceutical Chemistry written by Donald Cairns and published by Pharmaceutical Press. This book was released on 2012 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. Essentials of Pharmaceutical Chemistry is a chemistry introduction that covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules. Now a core text on many university courses, it contains numerous worked examples and problems
Download or read book Phytomedicines Herbal Drugs and Poisons written by Ben-Erik van Wyk and published by University of Chicago Press. This book was released on 2015-06-22 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants have been used to treat disease throughout human history. On a clay slab that dates back approximately five thousand years, the Sumerians recorded medicinal recipes that made use of hundreds of plants, including poppy, henbane, and mandrake. During the Middle Ages, monks commonly grew and prescribed plants such as sage, anise, and mint in their monasteries. And as the market for herbal remedies and natural medicine grows, we continue to search the globe for plants and plant compounds to combat our various ailments. In Phytomedicines, Herbal Drugs, and Poisons, Ben-Erik van Wyk offers a richly illustrated, scientific guide to medicinal and poisonous plants, including those used for their mind-altering effects. Van Wyk covers approximately 350 species—from Aloe vera and Ephedra sinica to Cannabis sativa and Coffea arabica—detailing their botanical, geographical, pharmacological, and toxicological data as well as the chemical structures of the active compounds in each. Readers learn, for example, that Acacia senegal, or gum acacia, is used primarily in Sudan and Ethiopia as a topical ointment to protect the skin and mucosa from bacterial and fungal infections, and that Aconitum napellus, more commonly known as aconite, is used in cough syrups but can be psychedelic when smoked or absorbed through the skin. With 350 full-color photographs featuring the plants and some of their derivative products, Phytomedicines, Herbal Drugs, and Poisons will be an invaluable reference not only for those in the health care field but also for those growing their own medicinal herb gardens, as well as anyone who needs a quick answer to whether a plant is a panacea or a poison.
Download or read book Natural Product Chemistry for Drug Discovery written by Antony D Buss and published by Royal Society of Chemistry. This book was released on 2009-10-21 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Product Chemistry for Drug Discovery provides a comprehensive summary of where natural product chemistry is today in drug discovery. The book covers emerging technologies and case studies and is a source of up-to-date information on the topical subject of natural products. Natural products are once again considered important tools in the drug discovery toolbox. The authors are all experts in their respective fields of natural product chemistry. The book will appeal across the board from scientists to professionals, postgraduates and industrial chemists. The case studies selected for inclusion highlight recently marketed drugs and development candidates that have been derived from natural products. These 'real-life' examples show how new technologies, such as advances in screening, isolation, dereplication and prefractionation, have significantly enhanced the discovery process.
