Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Download or read book Evaluating Drug Control and System Improvement Projects written by and published by . This book was released on 1989 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-06 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Download or read book National Drug Control Strategy written by United States. Office of National Drug Control Policy and published by . This book was released on 1995 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book National Drug Control Strategy written by United States. President (1989-1993 : Bush) and published by . This book was released on 1992 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The National Drug Control Strategy written by United States. Congress. House. Committee on Government Operations. Legislation and National Security Subcommittee and published by . This book was released on 1993 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The National Drug Control Strategy written by United States. Office of National Drug Control Policy and published by . This book was released on 1997 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Strategies to Modify the Drug Release from Pharmaceutical Systems written by Marcos Luciano Bruschi and published by Woodhead Publishing. This book was released on 2015-06-16 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery. Strategies to Modify the Drug Release from Pharmaceutical Systems will address principles, systems, applications and advances in the field.It will be principally a textbook and a reference source of strategies to modify the drug release. Moreover, the characterization, mathematical and physicochemical models, applications and the systems will be discussed. - Addresses the principles, systems, applications and advances in the field of drug delivery - Highlights the mathematical and physicochemical principles related to strategies - Discusses drug release and its possible modifications
Download or read book Modeling and Control of Drug Delivery Systems written by Ahmad Taher Azar and published by Academic Press. This book was released on 2021-02-06 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy. - Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring - Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area - Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS
Download or read book National Drug Control Strategy 2010 written by and published by DIANE Publishing. This book was released on 2011-04 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: Intro.: Launching a New Approach to America¿s Drug Problem; (1) Strengthen Efforts to Prevent Drug Use; Drug-Related Challenges in Tribal Communities; (2) Early Intervention Opportunities in Health Care; Oper. Med. Cabinet NJ: Statewide Day of Disposal of Unused, Unwanted, and Expired Medicine; (3) Integrate Treatment for Substance Use Disorders into Health Care, and Expand Support for Recovery; Family Treatment for Addicted Mothers and Their Children; (4) Break the Cycle of Drug Use, Crime, Delinquency, and Incarceration; Vets Treatment Courts; Reducing Recidivism through Testing and Sanctions; (5) Disrupt Domestic Drug Trafficking and Production; Fighting Meth Labs; (6) Plan Colombia; Internat. Interdiction. Charts and tables.
Download or read book National Drug Control Strategy 1992 written by J. R. Roberts and published by DIANE Publishing. This book was released on 1992-06 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Role of NIH in Drug Development Innovation and Its Impact on Patient Access written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-01-27 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: To explore the role of the National Institutes of Health (NIH) in innovative drug development and its impact on patient access, the Board on Health Care Services and the Board on Health Sciences Policy of the National Academies jointly hosted a public workshop on July 24â€"25, 2019, in Washington, DC. Workshop speakers and participants discussed the ways in which federal investments in biomedical research are translated into innovative therapies and considered approaches to ensure that the public has affordable access to the resulting new drugs. This publication summarizes the presentations and discussions from the workshop.
Download or read book State Strategic Planning Under the Drug Formula Grant Program written by Terence Dunworth and published by DIANE Publishing. This book was released on 1994-05 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book 2010 National Drug Control Strategy written by United States. President (2009-2017 : Obama) and published by . This book was released on 2010 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Data Resources of the National Institute of Justice written by National Institute of Justice (U.S.) and published by . This book was released on 1996 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Data Resources of the National Institute of Justice written by and published by . This book was released on 1995 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Act to Prevent the Manufacturing Distribution and Use of Illegal Drugs and for Other Purposes written by United States and published by . This book was released on 1989 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:
