Download or read book Dopamine in the CNS II written by Gaetano Di Chiara and published by Springer Science & Business Media. This book was released on 2002-06-27 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Download or read book Dopamine in the CNS I written by Gaetano Di Chiara and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Download or read book Caffeine in Food and Dietary Supplements written by Leslie A. Pray and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Caffeine in Food and Dietary Supplements is the summary of a workshop convened by the Institute of Medicine in August 2013 to review the available science on safe levels of caffeine consumption in foods, beverages, and dietary supplements and to identify data gaps. Scientists with expertise in food safety, nutrition, pharmacology, psychology, toxicology, and related disciplines; medical professionals with pediatric and adult patient experience in cardiology, neurology, and psychiatry; public health professionals; food industry representatives; regulatory experts; and consumer advocates discussed the safety of caffeine in food and dietary supplements, including, but not limited to, caffeinated beverage products, and identified data gaps. Caffeine, a central nervous stimulant, is arguably the most frequently ingested pharmacologically active substance in the world. Occurring naturally in more than 60 plants, including coffee beans, tea leaves, cola nuts and cocoa pods, caffeine has been part of innumerable cultures for centuries. But the caffeine-in-food landscape is changing. There are an array of new caffeine-containing energy products, from waffles to sunflower seeds, jelly beans to syrup, even bottled water, entering the marketplace. Years of scientific research have shown that moderate consumption by healthy adults of products containing naturally-occurring caffeine is not associated with adverse health effects. The changing caffeine landscape raises concerns about safety and whether any of these new products might be targeting populations not normally associated with caffeine consumption, namely children and adolescents, and whether caffeine poses a greater health risk to those populations than it does for healthy adults. This report delineates vulnerable populations who may be at risk from caffeine exposure; describes caffeine exposure and risk of cardiovascular and other health effects on vulnerable populations, including additive effects with other ingredients and effects related to pre-existing conditions; explores safe caffeine exposure levels for general and vulnerable populations; and identifies data gaps on caffeine stimulant effects.

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Download or read book Dopamine Nation written by Dr. Anna Lembke and published by Penguin. This book was released on 2023-01-03 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: INSTANT NEW YORK TIMES and LOS ANGELES TIMES BESTSELLER “Brilliant . . . riveting, scary, cogent, and cleverly argued.”—Beth Macy, author of Dopesick, as heard on Fresh Air This book is about pleasure. It’s also about pain. Most important, it’s about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We’re living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting . . . The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we’ve all become vulnerable to compulsive overconsumption. In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain . . . and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Environmental Neurotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Download or read book Attention in Cognitive Systems Theories and Systems from an Interdisciplinary Viewpoint written by Lucas Paletta and published by Springer. This book was released on 2007-12-03 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a much-needed interdisciplinary angle on the subject of attention in cognitive systems. It constitutes the thoroughly refereed post-workshop proceedings of the 5th International Workshop on Attention in Cognitive Systems, held in Hyderabad, India, in January 2007. The 31 papers are organized in topical sections that cover every aspect of the subject, from the embodiment of attention and its cognitive control, to the applications of attentive vision.

Download or read book The Molecule of More written by Daniel Z. Lieberman and published by BenBella Books. This book was released on 2018-08-14 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why are we obsessed with the things we want only to be bored when we get them? Why is addiction perfectly logical to an addict? Why does love change so quickly from passion to indifference? Why are some people die-hard liberals and others hardcore conservatives? Why are we always hopeful for solutions even in the darkest times—and so good at figuring them out? The answer is found in a single chemical in your brain: dopamine. Dopamine ensured the survival of early man. Thousands of years later, it is the source of our most basic behaviors and cultural ideas—and progress itself. Dopamine is the chemical of desire that always asks for more—more stuff, more stimulation, and more surprises. In pursuit of these things, it is undeterred by emotion, fear, or morality. Dopamine is the source of our every urge, that little bit of biology that makes an ambitious business professional sacrifice everything in pursuit of success, or that drives a satisfied spouse to risk it all for the thrill of someone new. Simply put, it is why we seek and succeed; it is why we discover and prosper. Yet, at the same time, it's why we gamble and squander. From dopamine's point of view, it's not the having that matters. It's getting something—anything—that's new. From this understanding—the difference between possessing something versus anticipating it—we can understand in a revolutionary new way why we behave as we do in love, business, addiction, politics, religion—and we can even predict those behaviors in ourselves and others. In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and why the brains of liberals and conservatives really are different.

Download or read book CNS Neurotransmitters and Neuromodulators written by Trevor W. Stone and published by CRC Press. This book was released on 2020-10-28 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series CNS Neurotransmitters and Neuromodulators is destined to be the definitive reference work on the physiology and pharmacology of the central nervous system. Written by an outstanding group of international authors, chapters cover a wide range of interdisciplinary aspects of the subject. This first volume includes an in-depth examination of acetylcholine, ranging from the localization of synthetic enzymes through electrophysiology, pharmacology, and molecular biology to behavioral importance in learning and memory. This indispensable and comprehensive reference keeps you abreast of new developments in several areas of neuroscience.

Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq

Download or read book Food Components to Enhance Performance written by Institute of Medicine and published by National Academies Press. This book was released on 1994-02-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.

Download or read book Central Nervous System Diseases written by Dwaine F. Emerich and published by Springer Science & Business Media. This book was released on 1999-11-24 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prominent experimentalists critically review the animal models widely used in developing powerful new therapies for central nervous system diseases. Coverage includes novel uses of animal models of Alzheimer's, Parkinson's, and Huntington's diseases, and studies of aging. Techniques that rely heavily on behavioral analyses, as well as models developed from infusions of neurotoxins and from advances in molecular biology, are thoroughly explicated, as are models developed for more acute neurological conditions, including traumatic brain injury and stroke. Comprehensive and authoritative, Central Nervous System Diseases: Innovative Animal Models from Lab to Clinic offers neuroscientists, pharmacologists, and interested clinicians a unique survey of the most productive animal models of the leading neurological diseases currently employed to develop today's innovative drug therapies.

Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Download or read book The Dopaminergic Mind in Human Evolution and History written by Fred H. Previc and published by Cambridge University Press. This book was released on 2009-05-14 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: What does it mean to be human? There are many theories of the evolution of human behavior which seek to explain how our brains evolved to support our unique abilities and personalities. Most of these have focused on the role of brain size or specific genetic adaptations of the brain. In contrast, in this text, Fred Previc presents a provocative theory that high levels of dopamine, the most widely studied neurotransmitter, account for all major aspects of modern human behavior. He further emphasizes the role of epigenetic rather than genetic factors in the rise of dopamine. Previc contrasts the great achievements of the dopaminergic mind with the harmful effects of rising dopamine levels in modern societies and concludes with a critical examination of whether the dopaminergic mind that has evolved in humans is still adaptive to the health of humans and to the planet in general.

Download or read book Histamine in the brain written by Jian-Sheng Lin and published by Frontiers Media SA. This book was released on 2015-03-18 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain aminergic pathways are organized in parallel and interacting systems, which support a range of functions, from homoeostatic regulations to cognitive, and motivational processes. Despite overlapping functional influences, dopamine, serotonin, noradrenaline and histamine systems provide different contributions to these processes. The histaminergic system, long ignored as a major regulator of the sleep-wake cycle, has now been fully acknowledged also as a major coordinator of attention, learning and memory, decision making. Although histaminergic neurons project widely to the whole brain, they are functionally heterogeneous, a feature which may provide the substrate for differential regulation, in a region-specific manner, of other neurotransmitter systems. Neurochemical preclinical studies have clearly shown that histamine interacts and modulates the release of neurotransmitters that are recognized as major modulators of cognitive processing and motivated behaviours. As a consequence, the histamine system has been proposed as a therapeutic target to treat sleep-wake disorders and cognitive dysfunctions that accompany neurodegenerative and neuroinflammatory pathologies. Last decades have witnessed an unexpected explosion of interest in brain histamine system, as new receptors have been discovered and selective ligands synthesised. Nevertheless, the complete picture of the histamine systems fine-tuning and its orchestration with other pathways remains rather elusive. This Research Topic is intended to offer an inter-disciplinary forum that will improve our current understanding of the role of brain histamine and provide the fundamentals necessary to drive innovation in clinical practice and to improve the management and treatment of neurological disorders.

Download or read book Catecholamine Research written by Toshiharu Nagatsu and published by Springer Science & Business Media. This book was released on 2002-10-31 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of catecholamine research has not undergone comprehensive review for four years. In the interim, a tremendous amount of new information, obtained using molecular, genetic, neurochemical, and nuclear scanning techniques, has substantiated the important roles of catecholamine systems in development, cardiovascular function, psychiatric disorders, neurodegenerative diseases, and metabolism. This volume, based on the Ninth International Catecholamine Symposium, will have a substantial and lasting impact on medical science.