Download or read book Disorders of the Human Adrenal Cortex written by Christa E. Flück and published by Karger Medical and Scientific Publishers. This book was released on 2008 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Substantial further advances in our understanding of adrenal development, steroid biosynthesis and adrenocortical disorders necessitate another look at this small but complex organ. In this volume, leaders in the fields of adrenal development, biochemistry and genetics review the most recent findings from bench and bedside research. New aspects of adrenal development and zonation and the novel 'backdoor' pathway to androgen synthesis are discussed. P450 oxidoreductase deficiency (a newly described form of congenital adrenal hyperplasia) and long-term outcome of prenatal treatment of 21-hydroxylase deficiency are examined. An update on ACTH resistance and adrenal Cushing's syndrome is provided. Finally, the role of adrenal steroidogenesis in arterial hypertension and fetal programming of adrenal androgen excess as a possible explanation for polycystic ovary syndrome in later life are analyzed. This book will be of great interest to pediatric, adult and reproductive endocrinologists, clinical geneticists, developmental biologists and basic scientists working in the fields of endocrinology and steroidogenesis.
Download or read book Adrenal Cortex From Physiology to Disease written by Pierre Val and published by Frontiers Media SA. This book was released on 2016-07-18 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adrenal gland plays essential roles in the control of body homeostasis, stress and immune responses. The adrenal cortex represents up to 90% of the gland and is specialised in the production of mineralocorticoids, glucocorticoids and adrenal androgens. This production is tightly coordinated and results from a unique zonal organisation. Although our knowledge of the molecular mechanisms controlling adrenal steroidogenesis is quite extensive, for decades, the mechanisms of adrenal cortex development, cellular homeostasis and renewal have remained elusive. The advent of new high-throughput technologies and sophisticated genetic approaches has brought tremendous progress in our understanding of how the adrenal cortex achieves and maintains its particular organisation. The aim of this Frontiers in Endocrinology Topic is to provide readers with a snapshot of our current knowledge on adrenal physiology and how deregulations of these processes result in adrenal diseases. This includes but is not limited to, basic research on adrenal development, cell lineage identification, progenitor cells, tissue renewal, control of differentiation and zonation and clinical research on the identification of disease-related genes.
Download or read book The Human Adrenal Cortex Volume 8 written by G. E. W. Wolstenholme and published by John Wiley & Sons. This book was released on 2009-09-17 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Download or read book The Human Adrenal Cortex written by A.M. Neville and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: We would like to take this opportunity of expressing our sincerest thanks to the many persons who have made adrenal tissue and related materials available to us for our work. Our especial gratitude is extended to Drs. J.J. Brown, A. Lever and J.I.S. Robertson of the M.R.C. Blood Pressure Unit, Glasgow, Dr. J.K. Grant, Royal Infirmary, Glasgow, Professor R.B. Welbourn and Dr. W. Kelly, Royal Postgraduate Medical School, Drs. D.B. Grant of Great Ormond Street, J. Ginsberg, Royal Free Hospital, D.C. Anderson, Hope Hospital, Salford, C.R. Edwards, St. Bartholomew's Hospital and Professor I. Doniach (for merly of the London Hospital) and Messrs. J.-c. Gazet, A. McKinna and P. Greening, Royal Marsden Hospital, London. The preparation and presentation of the material and the results would not have been possible without the help of Dr. P. Monaghan and his Electron Microscopy Unit, Ludwig Institute for Cancer Research (London Branch), Sutton, Mrs. Mitchell and her Histology Team, Royal Marsden Hospital, Sutton, Mr. K. Moreman of the Photographic Department of the Royal Marsden Hospital and Institute of Cancer Research, London and Mr. M. Hughes for graphics. Particular thanks are due for the untiring efforts and assistance ofMr. J. Ellis and Mrs. D. Corney of the Ludwig Institute for Cancer Research (London Branch), Sutton, for most of the photographic and secretarial work respectively. Professors G. Dhom and E. Mausle kindly provided material for Figs.
Download or read book The Human Adrenal Cortex written by N. P. Christy and published by HarperCollins Publishers. This book was released on 1971 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Adrenal Disorders written by Andrew N. Margioris and published by Springer Science & Business Media. This book was released on 2001-04-20 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Adrenal Disorders, a panel of distinguished physicians and researchers select the most relevant new findings and integrate them into the existing body of clinical knowledge on adrenal pathologies. The book includes important reviews of disturbances in cortisol homeostasis, and new concepts regarding adrenal tumors and hereditary adrenal diseases. Also discussed are mineralocorticoids and the syndromes of mineralocortoid excess and aldosterone synthase deficiency. Authoritative and insightful, Adrenal Disorders provides physicians and scientists with a comprehensive, state-of-the-art practical guide to the devastating diseases of the adrenals that are so often difficult to diagnose and treat.
Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.
Download or read book Disorders of the Human Adrenal Cortex Endocrine Development written by C. E. Flück and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Substantial further advances in our understanding of adrenal development, steroid biosynthesis and adrenocortical disorders necessitate another look at this small but complex organ. In this volume, leaders in the fields of adrenal development, biochemistry and genetics review the most recent findings from bench and bedside research. New aspects of adrenal development and zonation and the novel 'backdoor' pathway to androgen synthesis are discussed. P450 oxidoreductase deficiency (a newly described form of congenital adrenal hyperplasia) and long-term outcome of prenatal treatment of 21-hydroxylase deficiency are examined. An update on ACTH resistance and adrenal Cushing's syndrome is provided. Finally, the role of adrenal steroidogenesis in arterial hypertension and fetal programming of adrenal androgen excess as a possible explanation for polycystic ovary syndrome in later life are analyzed. This book will be of great interest to pediatric, adult and reproductive endocrinologists, clinical geneticists, developmental biologists and basic scientists working in the fields of endocrinology and steroidogenesis.
Download or read book Adrenal Disease in Childhood written by I. A. Hughes and published by Karger Medical and Scientific Publishers. This book was released on 2000-01-01 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adrenal disease in children poses an immensely difficult diagnostic and management problem for the paediatrician in view of the large number of rare pathologies that may present in this way. This volume brings together the expertise of the acknowledged leaders in specific adrenal disorders to provide a readily accessible text that combines a detailed description of the molecular origins of these diseases, as they are currently understood, with a unique account of the clinical features and therapeutic options. Beginning with disorders that primarily affect adrenal development and progressing towards the defects that interfere with steroid production, the reader gains considerable insight into the normal physiology of the adrenal cortex particularly as revealed by clinical disorders. The major contributions of modern biochemistry and molecular genetics in our current understanding are visible throughout, providing a unique overview of adrenocortical biology. This book is of great interest to general pediatricians, paediatric endocrinologists, adult endocrinologists, clinical geneticists and basic scientists working in areas such as developmental biology and molecular steroidogenesis.
Download or read book Functional Pathology of the Human Adrenal Gland written by Thomas Symington and published by Churchill Livingstone. This book was released on 1969 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Adrenal Cortex written by David C. Anderson and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adrenal Cortex presents a critical review of functional and structural zonation of the cortex. It discusses the regulation of adrenocortical function by control of growth and structure. It also addresses the adrenal cortex in the fetus and neonate. It demonstrates the cellular mechanisms involved in the acute and chronic actions of ACTH. Some of the topics covered in the book are the molecular structures of mineralocorticoid and glucocorticoid receptors; description of adrenarche and adrenal hirsutism; types of congenital enzymatic defects of the adrenal; aetiology and management of Cushing's syndrome; and the relationship between adrenal cortex and hypertension. The description and characteristics of adrenocortical dysfunction are fully covered. The interactions between the adrenal cortex and medulla are extensively discussed. An in-depth analysis of the pharmacokinetics of natural and synthetic glucocorticoids is provided. A study of the regulation of normal steroidogenesis by adrenocortical structure is well presented. A chapter is devoted to possible role of vascular system in neural stimulations. The book can provide useful information to neurologists, doctors, students, and researchers.
Download or read book Pediatric Adrenal Diseases written by Lucia Ghizzoni and published by Karger Medical and Scientific Publishers. This book was released on 2011 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts and specialized investigators, this book presents a detailed overview of the recent progress in our understanding of the adrenal cortex and its pivotal roles in homeostasis. Genes, molecules and cell compartments directly or indirectly involved in the complex steroidogenesis pathway as well as the resulting end-hormones glucocorticoids, mineralocorticoids and androgens are analyzed. Furthermore, the defects of the genes responsible both for common and rare adrenal disorders are presented. The interactions of the adrenal cortices with the adrenal medulla and their importance in the integration of adrenocortical and adrenomedullary function are discussed. The complex molecular pathophysiology of congenital adrenal hyperplasia is presented; long-term effects of the disorder and the still controversial antenatal therapy are examined. Finally, expert review chapters discuss autoimmune Addison disease and the adrenoleukodystrophy/adrenomyeloneuropathy syndrome. Presenting novel research findings in adrenal gland physiology and pathophysiology, this book is a useful tool not only for pediatric endocrinologists, but also for clinicians and researchers studying human development, organogenesis, mitochondrial biology, nuclear receptors, stress biology and pharmacology.
Download or read book Pathophysiology of Disease An Introduction to Clinical Medicine 7 E ENHANCED EBOOK written by Gary D. Hammer and published by McGraw Hill Professional. This book was released on 2014-03-22 with total page 779 pages. Available in PDF, EPUB and Kindle. Book excerpt: A full-color, case-based review of the essentials of pathophysiology--covering all major organs and systems The goal of this trusted text is to introduce you to clinical medicine by reviewing the pathophysiologic basis of 120 diseases (and associated signs and symptoms) commonly encountered in medical practice. The authors, all experts in their respective fields, have provided a concise review of relevant normal structure and function of each body system, followed by a description of the pathophysiologic mechanisms that underlie several common diseases related to that system. Each chapter of Pathophysiology of Disease concludes with a collection of case studies and questions designed to test your understanding of the pathophysiology of each clinical entity discussed. These case studies allow you to apply your knowledge to specific clinical situations. Detailed answers to each case study question are provided at the end of the book. This unique interweaving of physiological and pathological concepts will put you on the path toward thinking about signs and symptoms in terms of their pathophysiologic basis, giving you an understanding of the "why" behind illness and treatment. Features 120 case studies (9 new) provide an opportunity for you to test your understanding of the pathophysiology of each clinical entity discussed Checkpoint questions provide review and appear in every chapter Updates and revisions throughout this new edition reflect the latest research and developments Numerous tables and diagrams encapsulate important information Updated references for each chapter topic Pathophysiology of Disease is a true must-have resource for medical students preparing for the USMLE Step 1 exam, as well as students engaged in their clerkship studies. House officers, nurses, nurse practitioners, physicians’ assistants, and allied health practitioners will find its concise presentation and broad scope a great help in facilitating their understanding of common disease entities.
Download or read book The Adrenal Cortex a Scope Monograph written by John E. Bethune and published by . This book was released on 1974 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Adrenal Gland written by Vivian Hector Thomas James and published by Raven Press (ID). This book was released on 1992 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endocrine Hypertension written by Karel Pacak and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several genetic, biochemical and radiologic discoveries have impacted the management of endocrine hypertension, while surgical procedures have revolutionized treatment of patients with endocrine hypertension. This text contains the proceedings of a 2001 workshop on the topic.
Download or read book Adrenal Glands written by Diana Loreta Păun and published by BoD – Books on Demand. This book was released on 2024-01-31 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents an in-depth exploration of adrenal anatomy, physiology, and pathology, authored by a multidisciplinary team of international experts, providing an exposition of the current state of knowledge in the field of adrenal diseases and offering insights into the evolution of their management. The addressed pathologies are intricate and diverse, encompassing conditions such as Cushing’s disease, primary aldosteronism, pheochromocytoma, and congenital adrenal hyperplasia. Each pathology chapter delves into etiopathogenic aspects, clinical evidence, and therapeutic recommendations. This publication caters equally to endocrinologists and professionals from various medical disciplines, serving as a valuable resource for information on the adrenal gland from both a physiological and pathological perspective.
