Download or read book Dioxins and Health written by A. Schecter and published by Springer Science & Business Media. This book was released on 1994-12-31 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book originated in a series of cross-disciplinary conversations in the years 1984-1990 between the editor, who is a physician-researcher involved in clinical and laboratory research, and a dioxin toxicologist. During the years in which the conversations took place, an extraordinary amount of new scientific literature was published related to dioxins, defined for purposes of this text as the chlorinated dibenzo-p-dioxins, dibenzofurans, polychlorinated biphe nyls (PCB's) and other compounds that are structurally and toxicologically similar to 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7 ,8-TCDD), the most extensively studied and most toxic of this group of chemicals. Dioxins also began to interest not only chemists and toxicologists, but also specialists from diverse disciplines such as wildlife and environmental science, immunology, neuroscience,public health, epidemiology, med icine, government, law, sociology, and journalism. Specialists from such varied disciplines, while familiar with their own literature, frequently did not have time to follow the dioxin literature outside their specialty area. In addition, each specialty had unique knowledge, methods, and perspectives. Cross disciplinary conversation was necessary, but all too frequently, specialists from the various disciplines did not speak the same language, resulting in misunderstanding.
Download or read book Veterans and Agent Orange written by Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides and published by National Academies Press. This book was released on 1994-01-15 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: Have U.S. military personnel experienced health problems from being exposed to Agent Orange, its dioxin contaminants, and other herbicides used in Vietnam? This definitive volume summarizes the strength of the evidence associating exposure during Vietnam service with cancer and other health effects and presents conclusions from an expert panel. Veterans and Agent Orange provides a historical review of the issue, examines studies of populations, in addition to Vietnam veterans, environmentally and occupationally exposed to herbicides and dioxin, and discusses problems in study methodology. The core of the book presents What is known about the toxicology of the herbicides used in greatest quantities in Vietnam. What is known about assessing exposure to herbicides and dioxin. What can be determined from the wide range of epidemiological studies conducted by different authorities. What is known about the relationship between exposure to herbicides and dioxin, and cancer, reproductive effects, neurobehavioral disorders, and other health effects. The book describes research areas of continuing concern and offers recommendations for further research on the health effects of Agent Orange exposure among Vietnam veterans. This volume will be critically important to both policymakers and physicians in the federal government, Vietnam veterans and their families, veterans organizations, researchers, and health professionals.
Download or read book Systems Biology in Toxicology and Environmental Health written by Rebecca Fry and published by Academic Press. This book was released on 2015-06-11 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. Introductory chapters on molecular and cellular biology, toxicology and computational biology are included as well as an assessment of systems-based tools used to evaluate environmental health risks. Further topics include research on environmental toxicants relevant to human health and disease, various high-throughput technologies and computational methods, along with descriptions of the biological pathways associated with disease and the developmental origins of disease as they relate to environmental contaminants. Systems Biology in Toxicology and Environmental Health is an essential reference for undergraduate students, graduate students, and researchers looking for an introduction in the use of systems biology approaches to assess environmental exposures and their impacts on human health. - Provides the first reference of its kind, demonstrating the application of systems biology in environmental health and toxicology - Includes introductions to the diverse fields of molecular and cellular biology, toxicology, and computational biology - Presents a foundation that helps users understand the connections between the environment and health effects, and the biological mechanisms that link them
Download or read book Dioxins in the Environment written by Great Britain. Central Directorate of Environmental Protection and published by . This book was released on 1989 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Profile for Chlorinated Dibenzo p dioxins written by and published by . This book was released on 1998 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Environmental Medicine written by Committee on Curriculum Development in Environmental Medicine and published by National Academies Press. This book was released on 1995-05-12 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: "Is the tap water safe to drink?" "Is it safe to live near power lines?" Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins.
Download or read book Veterans and Agent Orange written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-20 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: From 1962 to 1971, the U.S. military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academies of Sciences, Engineering, and Medicine was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations were conducted every two years to review newly available literature and draw conclusions from the overall evidence. Veterans and Agent Orange: Update 11 (2018) examines peer-reviewed scientific reports concerning associations between various health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published between September 30, 2014, and December 31, 2017, and integrates this information with the previously established evidence database.
Download or read book Human and Environmental Risks of Chlorinated Dioxins and Related Compounds written by Richard E. Tucker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing international concern is being expressed regarding the contamination of the environment with polychlorinated dibenzo-p dioxins (PCDDs) and polychlorinated dibenzofurans because certain of these chemicals have been shown to be highly toxic to animals and are ubiquitous in the environment. They are known to be distributed as contaminants of commercial products and as by-products from com bustion processes. A considerable volume of information has accumulated on these chemicals in the past two decades, particularly for the most toxic of them, 2,3,7,8-tetrach1orodibenzo-p-dioxin (2,3,7,8-TCDD). However, this body of knowledge has not succeeded in resolving genuine judgmental differences among experts in the field as to the degree of hazard to human health and the environment. In light of the widespread public concern, it is clearly imperative to come to grips with the continuing scientific controversy, to review the data, assess the issues, to see where areas of agreement exist, and where further research is needed to resolve remaining areas of disagree ment. This volume represents an effort to contribute to these goals.
Download or read book Dioxin and Related Compounds written by Mehran Alaee and published by Springer. This book was released on 2016-06-13 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a tribute to Professor Otto Hutzinger, the founding editor of The Handbook of Environmental Chemistry, in recognition of his pioneering work and contribution to our understanding of the sources, fate, exposure and effects of persistent organic pollutants. It consists of fourteen chapters written by individuals who have been inspired by his work and have followed in his footsteps by refining our knowledge of this field and opening new research directions. In Professor Hutzinger’s tradition of passing on valuable information to others, the authors present recent advances in areas such as inventories, remediation, and analytical determinations. Levels and trends in abiotic environments, biota, and human exposure via food, as well as the risks to the environment and humans from polychlorinated dibenzo dioxins, furans, and PCBs are also discussed. Other chapters deal with the relevant topics of DDT and its metabolites along with halogenated and phosphorus flame retardants.
Download or read book Marine Ecotoxicology written by Julián Blasco and published by Academic Press. This book was released on 2016-08-05 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine Ecotoxicology: Current Knowledge and Future Issues is the first unified resource to cover issues related to contamination, responses, and testing techniques of saltwater from a toxicological perspective. With its unprecedented focus on marine environments and logical chapter progression, this book is useful to graduate students, ecotoxicologists, risk assessors, and regulators involved or interested in marine waters. As human interaction with these environments increases, understanding of the pollutants and toxins introduced into the oceans becomes ever more critical, and this book builds a foundation of knowledge to assist scientists in studying, monitoring, and making decisions that affect both marine environments and human health. A team of world renowned experts provide detailed analyses of the most common contaminants in marine environments and explain the design and purpose of toxicity testing methods, while exploring the future of ecotoxicology studies in relation to the world's oceans. As the threat of increasing pollution in marine environments becomes an ever more tangible reality, Marine Ecotoxicology offers insights and guidance to mitigate that threat. - Provides practical tools and methods for assessing and monitoring the accumulation and effects of contaminants in marine environments - Unites world renowned experts in marine ecotoxicology to deliver thorough and diverse perspectives - Builds the foundation required for risk assessors and regulators to adequately assess and monitor the impact of pollution in marine environments - Offers helpful insights and guidance to graduate students, ecotoxicologists, risk assessors, and regulators interested in mitigating threats to marine waters
Download or read book Biosolids Applied to Land written by National Research Council and published by National Academies Press. This book was released on 2002-11-01 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1993 regulation (Part 503 Rule) governing the land application of biosolids was established to protect public health and the environment from reasonably anticipated adverse effects. Included in the regulation are chemical pollutant limits, operational standards designed to reduce pathogens and the attraction of disease vectors, and management practices. This report from the Board on Environmental Studies and Toxicology evaluates the technical methods and approaches used by EPA to establish those standards and practices, focusing specifically on human health protection. The report examines improvements in risk-assessment practices and advances in the scientific database since promulgation of the regulation, and makes recommendations for addressing public health concerns, uncertainties, and data gaps about the technical basis of the biosolids standards.
Download or read book Mill Town written by Kerri Arsenault and published by St. Martin's Press. This book was released on 2020-09-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the 2021 Rachel Carson Environmental Book Award Winner of the 2021 Maine Literary Award for Nonfiction Finalist for the 2020 National Book Critics John Leonard Prize for Best First Book Finalist for the 2021 New England Society Book Award Finalist for the 2021 New England Independent Booksellers Association Award A New York Times Editors’ Choice and Chicago Tribune top book for 2020 “Mill Town is the book of a lifetime; a deep-drilling, quick-moving, heartbreaking story. Scathing and tender, it lifts often into poetry, but comes down hard when it must. Through it all runs the river: sluggish, ancient, dangerous, freighted with America’s sins.” —Robert Macfarlane, author of Underland Kerri Arsenault grew up in the small, rural town of Mexico, Maine, where for over 100 years the community orbited around a paper mill that provided jobs for nearly everyone in town, including three generations of her family. Kerri had a happy childhood, but years after she moved away, she realized the price she paid for that childhood. The price everyone paid. The mill, while providing the social and economic cohesion for the community, also contributed to its demise. Mill Town is a book of narrative nonfiction, investigative memoir, and cultural criticism that illuminates the rise and collapse of the working-class, the hazards of loving and leaving home, and the ambiguous nature of toxics and disease with the central question; Who or what are we willing to sacrifice for our own survival?
Download or read book Dying from Dioxin written by Lois Marie Gibbs and published by South End Press. This book was released on 1995 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Now everyone has an opportunity to learn about dioxin and the issues surrounding it, in this well-presented, multifaceted book.' Theo Colborn, Senior Program Scientist, World Wildlife Fund (USA)In Dying From Dioxin, Lois Marie Gibbs and other scientists and activists describe the alarming details of the public health crisis surrounding dioxin, and explain how citizens can organize against this toxic threat.
Download or read book Agent Orange and Its Associated Dioxin written by Alvin L. Young and published by Elsevier Publishing Company. This book was released on 1988 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Halogenated Biphenyls Terphenyls Naphthalenes Dibenzodioxins and Related Products written by R.D. Kimbrough and published by Elsevier. This book was released on 2012-12-02 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemical industry is increasingly faced with problems arizing from chemicals produced during the manufacture of halogenated biphenyls or phenols. Knowledge of these chemicals and their destructive properties is sporadic, and the acute toxicity of this group varies widely. This informative revised edition presents the chemistry, environmental pollution problems, animal toxicology and information about structure-activity relationships. A brief overview is given of worker exposure and occupational illness. The book is divided into three parts: chemistry and environmental contamination; experimental toxicology; and human exposure and effects. Because of the great deal of interest in these compounds much new research work has been conducted since the first edition of this book was published. This revised edition has retained the effectiveness and clarity of the first edition, while being supplemented with new information, condensed old information, and examples of recent incidents.
Download or read book Reviews of Environmental Contamination and Toxicology 190 written by George Ware and published by Springer. This book was released on 2010-11-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews of Environmental Contamination and Toxicology attempts to provide concise and critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.
Download or read book Assessing the Human Health Risks of Trichloroethylene written by National Research Council and published by National Academies Press. This book was released on 2007-01-08 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trichloroethylene is a chlorinated solvent widely used as a degreasing agent in industrial and manufacturing settings. It is also used as a chemical intermediate in making other chemicals and is a component of products such as typewriter correction fluid, paint removers, adhesives, and spot removers. In 2001, EPA issued a draft health risk assessment and proposed exposure standards for trichloroethylene. PA's Scientific Advisory Board (SAB) reviewed the draft and it was issued for public comment. A number of scientific issues were raised during the course of these reviews. Assessing the Human Health Risks of Trichloroethylene identifies and assesses the key scientific issues relevant to analyzing the human health risks of trichloroethylene, considering pertinent toxicologic, epidemiologic, population susceptibility, and other available information, including relevant published scientific literature, EPA's 2001 draft health risk assessment of trichloroethylene, scientific and technical comments received by EPA from public and private sources, and additional relevant information to be provided by the sponsoring agencies. This report highlights issues critical to the development of an objective, realistic, and scientifically balanced trichloroethylene health risk assessment. Guidance for hazard characterization of trichloroethylene is presented in Chapters 2 through 10. Chapter 2 provides guidance for evaluating large sets of epidemiologic data. In Chapter 3, the committee applies this guidance as an example in its evaluation of the epidemiologic data on trichloroethylene and kidney cancer, and this example should help guide evaluations of other cancer risks. Chapter 3 also assesses new information on the kidney toxicity of trichloroethylene and its metabolites and potential modes of action. Chapters 4, 5, 6, 7, and 8 evaluate the key issues regarding liver toxicity and cancer, reproductive and developmental toxicity, neurotoxicity, respiratory tract toxicity and cancer, and immunotoxicity, respectively. However, the committee's review focused on mode-of-action information to understand how trichloroethylene might affect certain processes differently in different species. Chapter 9 discusses susceptibility to trichloroethylene and its metabolites, and Chapter 10 describes important factors in considering trichloroethylene in mixtures. Physiologically based pharmacokinetic models are evaluated in Chapter 11, and guidance is provided on future directions for model development. Finally, Chapter 12 considers issues related to dose-response assessment and quantitative assessment of risk.
