Download or read book Dimension Reduced Modeling of Blood Flow in Large Arteries written by Tobias Köppl and published by Springer Nature. This book was released on 2023-07-15 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph contains an in-depth and coherent treatment of dimension-reduced modeling of blood flows on the level of large vessels (macrocirculation). The authors reduce the complexity by combining a one-dimensional Navier-Stokes equation and a simplified FSI-concept. The influence of omitted vessels, which are subsequent to the outlets of larger vessels, is accounted for by systems of ordinary differential equations (0D models). The target audience primarily comprises research experts in the field of biomedical engineering, but the book may also be beneficial for graduate students alike.
Download or read book Mathematical Modeling of Blood Flow Through Stenosed Arteries written by Mohammed Musad and published by LAP Lambert Academic Publishing. This book was released on 2012-04 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: In mathematical bio-sciences we study the applications of mathematical modeling and mathematical techniques to get an insight into the problems of bio-sciences. The mathematical model is a comprehensive process of representing real Phenomena in terms of Mathematical Equations, and extracting from them useful information for understanding and predicting the process of idealization. The study of blood flow characteristics in human circulatory system in the presence of stenosis, has been the subject of researchers in recent years. A serious study of this problem has been done by Young 1968 who presented a mathematical model to analyses theoretically the effects of stenosis on flow characteristics of blood and concluded that the resistance to the flow and the wall shear stress increase with the increase in stenosis size. The blood flow through large arteries considered as Newtonian flow by Lee JS 1974. while the blood flow through small arteries is considered as non-Newtonian by Chan et all 2007.
Download or read book Biological Flow in Large Vessels written by Valerie Deplano and published by John Wiley & Sons. This book was released on 2022-06-28 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines recent methods used for blood flow modeling and associated in vivo experiments, conducted using experimental data from medical imaging. Different strategies are proposed, from smallscale models to complex 3D modeling using modern computational codes. The geometries are wide-ranging and deal with the narrowing and widening of sections (stenoses, aneurysms), bifurcations, geometries associated with prosthetic elements, and even cases of vessels with smaller dimensions than those of the blood cells circulating in them. Biological Flow in Large Vessels provides answers to the question of how medical and biomechanical knowledge can be combined to address clinical problems. It offers guidance for further development of numerical models, as well as experimental protocols applied to clinical research, with tools that can be used in real-time and at the patient’s bedside, for decision-making support, predicting the progression of pathologies, and planning personalized interventions.
Download or read book Patient specific modeling of geometry and blood flow in large arteries written by Luca Antiga and published by . This book was released on 2002 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Analysis and Sensitivity Study of Zero dimensional Modeling of Human Blood Circulation Network written by Roussel Rahman and published by . This book was released on 2017 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: The systemic circulation has a large number of vessels; therefore, 3-D simulation of pulse-wave propagation in the entire cardiovascular system is difficult and computationally expensive. Zero-Dimensional (Zero-D) and One-Dimensional (1-D) models are simplified representations of the cardiovascular network; they can be coupled as supplements to regional 3-D models for closed-loop multi-scale studies or be simulated as self-sufficient representations of the blood-flow network. Unlike Zero-D models, 1-D models can provide linear space-wise information for the vessels. However, Zero-D models can prove to be more useful in particular cases; as flexibility in adjusting parameters facilitate in tailoring the model to specific needs. A prevalent reservation regarding the Zero-D models has been the inconsistency of parameter adjustment. A primary objective of this work is to build a closed loop cardiovascular model with a consistent, easily replicable methodology so that the model (1) can be adopted in multi-scale studies and (2) can provide a quick clinical tool for patient-specific studies. Fifty-five large arteries were represented individually and the rest of the cardiovascular network was lumped into several equivalent components. This way, arbitrary parameter adjustments have been restricted to the microcirculation and venous sections only. The model was validated by comparing simulated hemodynamic properties with clinical measurements and simulations from a comparable 1-D model. The Zero-D simulations have been shown to be in excellent agreement with the 1-D predictions, despite their discrete nature in space being contrary to linearly continuous 1-D counterpart. An advantageous characteristic of the developed model is the retention of physiological definitions, especially for the arterial network. Therefore, the model can be conveniently modified for patient-specific simulations. The generality of the method and closed-loop nature of the model also allow to inquisitively study various mathematical assumptions in blood flow modeling and experimental techniques. As an example, a possible source of non-physiological wave reflections has been studied in this thesis. The developed Zero-D model was found to be quite sensitive to the diastolic function of the left ventricle (LV). Therefore, several aspects of the mathematical modeling of ventricular elastance and LV-aorta coupling have been investigated in terms of measured responses from a healthy heart. Moreover, a few conventional assumptions of Zero-D modeling have been studied and found to be quite accurate with respect to 1-D simulations. Finally, the scopes for future studies and suitability of the model to certain applications have been discussed.
Download or read book Snapshots of Hemodynamics written by Nico Westerhof and published by Springer Science & Business Media. This book was released on 2006-01-12 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemodynamics makes it possible to characterize in a quantitative way, the function of the heart and arterial system, thereby producing information about what genetic and molecular processes are of importance for cardiovascular function. Snapshots of Hemodynamics: An Aid for Clinical Research and Graduate Education by Nico Westerhof, Nikos Stergiopulos and Mark I. M. Noble is a quick reference guide designed to help basic and clinical researchers as well as graduate students to understand hemodynamics. The layout of the book provides short and independent chapters that provide teaching diagrams as well as clear descriptions of the essentials of basic and applied principles of hemodynamics. References are provided at the end of each chapter for further reading and reference.
Download or read book Cardiovascular Mathematics written by Luca Formaggia and published by Springer Science & Business Media. This book was released on 2010-06-27 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.
Download or read book Basic Sciences for MCEM written by Chetan Trivedy and published by CRC Press. This book was released on 2016-05-15 with total page 771 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a dedicated resource for those sitting the Part A of the MCEM (Membership of the College of Emergency Medicine) examination. It forms an essential revision guide for emergency trainees who need to acquire a broad understanding of the basic sciences, which underpin their approach to clinical problems in the emergency department. Common clinical scenarios are used to highlight the essential underlying basic science principles, providing a link between clinical management and a knowledge of the underlying anatomical, physiological, pathological and biochemical processes. Multiple choice questions with reasoned answers are used to confirm the candidates understanding and for self testing. Unlike other recent revision books which provide MCQ questions with extended answers, this book uses clinical cases linked to the most recent basic science aspects of the CEM syllabus to provide a book that not only serves as a useful revision resource for the Part A component of the MCEM examination, but also a unique way of understanding the processes underlying common clinical cases seen every day in the emergency department. This book is essential for trainees sitting the Part A of the MCEM exam and for clinicians and medical students who need to refresh their knowledge of basic sciences relevant to the management of clinical emergencies.
Download or read book Simulation of 3 D Blood Flow in the Full Systemic Arterial Tree and Computational Frameworks for Efficient Parameter Estimation written by Nan Xiao and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational methods for simulating blood flow have become powerful tools to gain insight into the physical behavior of the cardiovascular system in health and disease. This work is aimed at developing computational tools and models for the investigation of age-related arterial stiffening and its relationship to the underlying hemodynamics. Due to the complex geometry and spatially-varying material properties of the central arteries, and the hemodynamics therein, large-scale three-dimensional computational models of arterial mechanics can improve our ability to interpret current clinical hemodynamic metrics and to advance our fundamental understanding of the mechanisms of disease progression. We have built a novel computational model of fully three-dimensional and unsteady hemodynamics within the primary large arteries in the human systemic circulation from head to legs. We demonstrated that this virtual full body systemic arterial tree is able to reproduce many of the key local and global hemodynamic features of the human arterial circulation and is a promising first step toward further computational analyses of the relationship between blood flow and arterial stiffening. As part of this work, we have tested and implemented an important boundary condition for the arterial fluid-solid interaction problem that mimics the tethering effect of the external tissues and stabilizes simulations in large networks of vessels. The task of efficiently fitting large-scale 3-D models to patient-specific measurements is challenging due to the computational effort required for a single simulation and the number of model parameters involved. We implemented two different computational frameworks for parameter estimation: the first is based on computationally inexpensive one-dimensional analogues of the full 3-D system. The second method is based on sequential data-assimilation techniques, specifically, nonlinear Kalman filtering. We demonstrate that these frameworks may be used to rapidly estimate the parameters of large-scale 3-D models based on clinical measurements of blood flow, pressure, and vessel wall distensibility.
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Three dimensional Finite Element Modeling of Blood Flow in the Coronary Arteries written by and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Three-dimensional finite element modeling of blood flow in the coronary arteries.
Download or read book Modelling Blood Flow in Large Arteries Using the Finite Volume Method written by Anna Magdalena De Villiers and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finite volume method -- Blood flow -- 1D -- Staggered grid -- Characteristic system -- Eindige volume metode -- Bloedvloei -- Groot arteries -- Verspringende rooster -- Karakteristieke stelsel.
Download or read book Biology and Mechanics of Blood Flows written by Marc Thiriet and published by Springer Science & Business Media. This book was released on 2007-12-20 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative book presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. This volume contains chapters on anatomy, physiology, continuum mechanics, as well as pathological changes in the vasculature walls including the heart and their treatments. Methods of numerical simulations are given and illustrated in particular by application to wall diseases.
Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Download or read book Regulation of Tissue Oxygenation Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Download or read book Blood Flow in Large Vessels written by Irina Surovtsova and published by . This book was released on 2002 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Model Reduction of Parametrized Systems written by Peter Benner and published by Springer. This book was released on 2017-09-05 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The special volume offers a global guide to new concepts and approaches concerning the following topics: reduced basis methods, proper orthogonal decomposition, proper generalized decomposition, approximation theory related to model reduction, learning theory and compressed sensing, stochastic and high-dimensional problems, system-theoretic methods, nonlinear model reduction, reduction of coupled problems/multiphysics, optimization and optimal control, state estimation and control, reduced order models and domain decomposition methods, Krylov-subspace and interpolatory methods, and applications to real industrial and complex problems. The book represents the state of the art in the development of reduced order methods. It contains contributions from internationally respected experts, guaranteeing a wide range of expertise and topics. Further, it reflects an important effor t, carried out over the last 12 years, to build a growing research community in this field. Though not a textbook, some of the chapters can be used as reference materials or lecture notes for classes and tutorials (doctoral schools, master classes).
