Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Differentiation and Immunology written by Katherine Brehme Warren and published by Elsevier. This book was released on 2014-07-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Differentiation and Immunology is a collection of papers that deals with molecular specificity—the link between immunology and differentiation. One paper reviews the status of regulation in bacteria or viruses, and extends the results to animal cells. The paper also investigates a single aspect of the control of immunoglobulin through the use of plasmacytomas. Another paper discusses the role of macrophages in the minimum theory to possibly account for the energetics of the reaction with receptors, or to the frequency of antigen-sensitive cells. Some papers investigate the immunogenic function of macrophages, the transition from monocyte to macrophage, the factors influencing the formation of macrophage lysosomes, and the origin of macrophage lysosomes. Other papers also discuss the immune response as a model system for studies on cellular differentiation, as well as the differentiation for collagen synthesis in cultured cells. One paper suggests that in differentiation, the changes that can occur in the properties of protozoan cells, perpetuated for long periods, are reversible, and can be a means for survival—as every cell line is also capable of being a germ line. This collection can prove valuable to bio-chemists, cellular biologists, micro-biologists, developmental biologists, and scientists involved in immunology research.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book T Cell Differentiation and Function in Tissue Inflammation written by Amit Awasthi and published by Frontiers Media SA. This book was released on 2020-03-11 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book T Helper Cell Differentiation and Their Function written by Bing Sun and published by Springer. This book was released on 2014-09-26 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will focus on the differentiation and regulation of subsets of CD4+ T cells. It will also cover other aspects of research on these cells, which has made great advances in recent years, such as subsets’ plasticity and their role in healthy and disease conditions. The book provides researchers and graduate students with a cutting-edge and comprehensive overview of essential research on CD4+ T cells.
Download or read book Mathematical Computational and Experimental T Cell Immunology written by Carmen Molina-París and published by Springer Nature. This book was released on 2021-01-04 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical, statistical, and computational methods enable multi-disciplinary approaches that catalyse discovery. Together with experimental methods, they identify key hypotheses, define measurable observables and reconcile disparate results. This volume collects a representative sample of studies in T cell immunology that illustrate the benefits of modelling-experimental collaborations and which have proven valuable or even ground-breaking. Studies include thymic selection, T cell repertoire diversity, T cell homeostasis in health and disease, T cell-mediated immune responses, T cell memory, T cell signalling and analysis of flow cytometry data sets. Contributing authors are leading scientists in the area of experimental, computational, and mathematical immunology. Each chapter includes state-of-the-art and pedagogical content, making this book accessible to readers with limited experience in T cell immunology and/or mathematical and computational modelling.
Download or read book Differentiation of B Lymphocytes written by Christopher J. Paige and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid progress continues to be made in understanding the molecular and cellular events that comprise B-Iymphocyte differentiation. This is due in part to the high level of inter est shown by many investigators from diverse disciplines, who find this subject suitable for addressing some of the fundamental issues of immunobiology. B-cell developmen tal models are being extensively used to investigate cell-cell interactions, molecular mediators of differentiation and proliferation, differential onset of gene programs, and gene rearrangement and expression, as well as the generation of the immune response itself. Not surprisingly, increased understanding of B-cell differentiation sometimes results from the application of new techniques that permit greater insight into the cells comprising the system and the genetic mechanisms by which these cells express their differentiative potential. However, experimental strategies based upon the novel application of established technologies have also led to the clarification of many issues, as well as to the discov ery of previously unrecognized problems. One problem, well recognized by those active in the field, is how to keep up with significant developments as they appear. The purpose of this book, part of a series devoted to analysing current issues in biology, is to help overcome this problem. No attempt at comprehensive cov erage of all of the issues has been made. Rather, a more thorough analysis of a few topics is presented.
Download or read book Mechanisms of Differentiation written by Paul B. Fisher and published by CRC Press. This book was released on 1990-09-20 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant recent advances in cell culture technology now permit a detailed biochemical and molecular analysis of differentiation in both normal and tumor cells. These studies are important in attempting to understand the complex factors involved in normal growth and development, as well as the abnormalities associated with carcinogenesis. Mechanisms of Differentiation, Volumes I and II, is comprised of review chapters addressing various topics of current interest in this important area of research. Topics discussed include genes controlling differentiation, changes in gene expression during differentiation, induction of differentiation, induction of differentiation as a mode of action of chemotherapeutic agents, and the effect of cell shape, growth factors and differentiation modulating agents on the differentiated cell phenotype. Mechanisms of Differentiation is valuable to researchers involved in differentiation and development, carcinogenesis, cell biology, chemotherapy, and immunology.
Download or read book Cooperation of Liver Cells in Health and Disease written by Z. Kmiec and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.
Download or read book T Lymphocyte Differentiation Antigens Advances in Research and Application 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt: T-Lymphocyte Differentiation Antigens: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about T-Lymphocyte Differentiation Antigens in a concise format. The editors have built T-Lymphocyte Differentiation Antigens: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about T-Lymphocyte Differentiation Antigens in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of T-Lymphocyte Differentiation Antigens: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Lymphocyte Differentiation Recognition and Regulation written by David H. Katz and published by Academic Press. This book was released on 2014-06-28 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphocyte Differentiation, Recognition, and Regulation provides an overview of the state of knowledge on cellular immunology. The focus is on animal work than on studies in man, although in certain areas human lymphocyte biology has been discussed in some detail. The book attempts to integrate information from diverse areas of cellular immunology, immunogenetics, and immunochemistry to form some cohesive concepts that can be perhaps utilized as a working foundation for students and investigators in various areas of immunology. The book begins with a general description of some of techniques and principles underlying the systems frequently employed in cellular immunology. This is followed by detailed analyses of lymphocyte differentiation, receptor function, and regulatory processes. The main points that emerge from such analyses are that the immune system is an infinitely complex and finely tuned network of cells, receptors, and molecules which interact with one another in a genetically controlled manner that is manifested ultimately in the process known as differentiation.
Download or read book Transcriptional Control of Lineage Differentiation in Immune Cells written by Wilfried Ellmeier and published by Springer. This book was released on 2014-09-02 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during the differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade.
Download or read book CD4 T cell differentiation in infection amendments to the Th1 Th2 axiom written by Dragana Jankovic and published by Frontiers Media SA. This book was released on 2015-06-03 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: CD4+ T lymphocytes play an essential role in host defense against bacterial, parasitic and viral infections. During infection, under the influence of intrinsic signals received through peptide-MHC/TCR interactions and extrinsic signals provided by pathogen-conditioned dendritic and other accessory cells, CD4+ T cells proliferate and differentiate into specialized T helper (Th) effectors, which produce distinct sets of cytokines tailored to combat a specific class of microbes. The concept of CD4+ T cell multi-functionality was developed after the seminal discovery of Th1 and Th2 cells nearly 30 years ago. Although the Th1/Th2 paradigm has successfully withstood the test of time, in the past decade additional Th subsets (Th17, Tfh, Th22, Th9) have been identified. Similarly, single cell analyses of cytokines and master transcriptional factors have revealed that, at the population level, CD4+ T cell responses are far more heterogeneous than initially anticipated. While some of the checkpoints in Th cell specification have been identified, recent studies of transcriptional and epigenetic regulation have uncovered a significant flexibility during the course CD4+ T lymphocyte polarization. In addition, Th cells expressing cytokines with counteracting functions, as a measure of self-regulation, display yet another level of diversity. Understanding the mechanisms that control the balance between stability vs. plasticity of Th effectors both at the time of initiation of immune response and during development of CD4 T cell memory is critical for the rational design of better vaccines and new immunotherapeutic strategies. This research topic will cover current views on Th cell development, with a focus on the mechanisms that govern differentiation, function and regulation of effector Th cells in the context of microbial infections.
Download or read book T Cell Differentiation Methods and Protocols written by Enrico Lugli and published by Methods in Molecular Biology. This book was released on 2018-11-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides protocols to successfully apply cutting-edge technologies to characterize the biology of T cells at an unprecedented level of complexity. Chapters guide readers through flow cytometry and fluorescence-activated cell sorting, the behaviour of single T cells after adoptive cell transfer (ACT), single cell gene expression by multiplex PCR, lentiviral transduction approaches, protocols to derive large numbers of early-differentiated memory T cells by using dedicated cytokines cocktails, approaches to measure telomerase activity in terminally differentiated T cells, and approaches to define Treg cells at the phenotypic and functional level. The final part of the book is dedicated to the analysis of the differentiation and effector functions of innate T cells, namely the well-known γ/δ T cells, and the recently identified CD8] mucosal associated invariant T (MAIT) cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, T-Cell Differentiation: Methods and Protocols aims to provide protocols that are fundamental to monitor the T cell compartment at the level of single cells in pathological and immunotherapy conditions.
Download or read book Fundamental Immunology written by William E. Paul and published by Lippincott Williams & Wilkins. This book was released on 2012-12-10 with total page 1313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental Immunology Seventh Edition This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed. Look inside and discover... * Fully revised and updated content reflects the latest advances in the field. * Current insights enhance readers' understanding of immune system function * Unique approach bridges the gap between basic immunology and the disease process. * Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. * Abundant illustrations and tables deliver essential information at a glance. PLUS... A convenient companion website features the fully searchable text with all references linked to PubMed. Pick up your copy today!
Download or read book T Lymphocyte Differentiation Antigens Advances in Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: T-Lymphocyte Differentiation Antigens—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about T-Lymphocyte Differentiation Antigens. The editors have built T-Lymphocyte Differentiation Antigens—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about T-Lymphocyte Differentiation Antigens in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of T-Lymphocyte Differentiation Antigens—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book B Cell Differentiation Antigens written by and published by . This book was released on 1982 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt:
