Download or read book Dietary Induction Models of Nutritional Disorders in Rodents written by Jailane de Souza Aquino and published by Cambridge Scholars Publishing. This book was released on 2023-06-16 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses one of the most controversial topics in Ethics and Bioethics since the beginning of physiology and comparative anatomy, as viewed from the perspective of experienced researchers in the fields of nutrition, bioethics and translational research. The book provides up-to-date information on dietary induction models of diabetes, obesity, hypertension, dyslipidaemia and malnutrition in experimental animal models, with a focus and direction for future clinical studies in the area of health sciences. It directly describes the importance of pre-clinical studies in the construction of translational research, being useful for academic-scientific institutions, students and health professionals such as nutritionists, doctors, pharmacists, psychologists, and nurses, among others.
Download or read book Dietary Induction Models of Nutritional Disorders in Rodents written by Jailane de Souza and published by . This book was released on 2023-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses one of the most controversial topics in Ethics and Bioethics since the beginning of physiology and comparative anatomy, as viewed from the perspective of experienced researchers in the fields of nutrition, bioethics and translational research. The book provides up-to-date information on dietary induction models of diabetes, obesity, hypertension, dyslipidaemia and malnutrition in experimental animal models, with a focus and direction for future clinical studies in the area of health sciences. It directly describes the importance of pre-clinical studies in the construction of translational research, being useful for academic-scientific institutions, students and health professionals such as nutritionists, doctors, pharmacists, psychologists, and nurses, among others.
Download or read book Nutrient Requirements of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 1995-02-01 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.
Download or read book Are Rodent Models Fit for Investigation of Human Obesity and Related Diseases written by Patrick C. Even and published by Frontiers Media SA. This book was released on 2018-02-15 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not only developed countries, but also most developing areas of the world, have experienced a surge in obesity prevalence over recent decades. Obesity complications are now among the leading causes of premature mortality, encompassing conditions such as coronary heart disease, stroke, and type 2 diabetes. This places a heavy burden on contemporary healthcare systems. While rodent models have limitations as experimental models of human obesity-related disease, study of rats and mice either spontaneously prone - or resistant - to obesity, or genetically engineered to illuminate underlying mechanisms has yielded key information about the metabolic defects linked to obesity, and their associated diseases. This topic includes both original research studies and reviews of the use of animal studies in specific areas of obesity-related disease. Various methodological approaches are discussed, with evaluation of the extent to which use of animal models has facilitated progress, or, conversely, has proved a cul de sac in investigation of human disease mechanisms. Consideration is also given to future strategies to use such rodent models optimally to enhance comprehension and treatment of pandemic human obesity-related diseases.
Download or read book Animal Models for the Study of Human Disease written by Louise Thibault and published by Elsevier Inc. Chapters. This book was released on 2013-05-29 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: This chapter aims to review literature on different aspects of obesity from fat-rich diets in non-human species. Usefulness of using small rodents in animal models to infer aspects of human obesity is discussed in terms of similarities and differences and how obesity is defined. The paradigm of using fat-rich diets in animal models of human obesity is explored according to its adequacy and dietary characteristics related to fatty acid composition. Physiological factors and mechanisms that can play a role in the development of obesity induced by a diet rich in fat are examined, namely the efficiency of nutrient utilization and the possible lack of inhibitory effect of fat on intake. The role of hormones such as leptin, ghrelin and insulin is discussed. Bevavioural mechanisms related to sensory-specific facilitation of eating with fat rich diets, altered feeding rhythmicity and learned eating are considered. The possible reversal of fat-rich diet induced obesity in animal models is explored. This chapter concludes with comments on appropriate design of animal studies and suggestions for future research.
Download or read book Use of Animal Models for Research in Human Nutrition written by Anton C. Beynen and published by . This book was released on 1988 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Models of Disease written by Cynthia Petrie Smith and published by . This book was released on 1992 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nutritional Aspects of Kidney Disease written by Alice Sabatino and published by Frontiers Media SA. This book was released on 2022-01-10 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bibliography of Agriculture written by and published by . This book was released on 1990 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quick Bibliography Series written by and published by . This book was released on 1976 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Environmental Epigenomics in Health and Disease written by Randy L. Jirtle and published by Springer Science & Business Media. This book was released on 2013-05-13 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs are established as stem cell differentiate during embryogenesis, and they are normally faithfully reproduced during mitosis. Moreover, they can also be maintained during meiosis, resulting in epigenetic transgenerational disease inheritance, and also potentially introducing phenotypic variation that is selected for in the evolution of new species. The objective of this two volume book is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular disease, diabetes, obesity, and schizophrenia later in life by modifying the epigenome. Consequently, epigenetic research promises to markedly improve our ability to diagnosis, prevent, and treat the pathological conditions of humans; however, it also introduces unique legal and ethical issues. This volume highlights the correlation between environmental factors and complex diseases, such as autism, addiction, neurological diseases, diabetes, obesity and cancer. It concludes with a chapter on legal and ethical implications of epigenetics.
Download or read book Pathophysiology of Obesity Induced Health Complications written by Paramjit S. Tappia and published by Springer Nature. This book was released on 2020-01-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the World Health Organization, the epidemic of global obesity has nearly tripled since 1975. In 2016, more than 1.9 billion adults were overweight, over 650 million of which were obese. Being overweight and obese has been linked to a number of non-communicable, chronic diseases. Pathophysiology of Obesity-Induced Health Complications is a compilation of review articles dedicated to describe co-morbidities associated with obesity. The wide range that is covered is of significant interest to basic research scientists, clinicians and graduate students who are engaged in studying obesity-induced health complications. Furthermore, this book highlights the potential of novel approaches for the prevention and treatment of obesity and its related illnesses. Nineteen articles in this book are organized in four sections that are designed to provide an overview of obesity-induced health complications. The first section serves as an introductory section on the prevalence, causes, consequences, treatments and preventive approaches for obesity. Section two covers the metabolic disturbances and inflammation due to obesity. The third section is focused on neurological and visceral complications as a consequence of obesity. The final section covers strategies for the prevention of obesity-induced complications. The book illustrates that obesity can result in a diverse range of pathophysiological conditions that adversely affect health.
Download or read book IGF and Nutrition in Health and Disease written by M. Sue Houston and published by Springer Science & Business Media. This book was released on 2004-08-04 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: A benchmark review on how specific nutrients or adverse nutritional states impact the components of the IGF (Insulin-like Growth Factor) system and affect human health and disease. The authors describe the fundamentals of the IGF system, explain its basic mechanisms of action, illuminate its essential role in physical development across the life span, and highlight the link between normal and abnormal cellular growth resulting in tumor formation. They also fully examine the clinical aspects of nutrition and IGF, from pre- and postnatal development through old age, in the maintenance of normal metabolism, bone, and muscle health, and their role in pathological states. Special attention is given to critical illness, diabetes, gastrointestinal diseases, kidney failure, endocrine dysfunctions, cardiovascular disease, neurological disorders, and cancer, as well as to their potential for IGF therapy.
Download or read book Role of Epigenetic Modifications on Diet Induced Metabolic Diseases written by Anna Alisi and published by Frontiers Media SA. This book was released on 2020-12-02 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Nutrition in the Prevention and Treatment of Abdominal Obesity written by Ronald Ross Watson and published by Elsevier. This book was released on 2014-02-26 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition in the Prevention and Treatment of Abdominal Obesity focuses on the important roles that exercise, dietary changes, and foods play in promoting as well as reducing visceral fat. Nutritionists, dieticians, and healthcare providers seeking to address the abdominal obesity epidemic will use this comprehensive resource as a tool in their long-term goal of preventing chronic diseases, especially heart, vascular, and diabetic diseases. Experts from a broad range of disciplines are involved in dealing with the consequences of excessive abdominal fat: cardiology, diabetes research, studies of lipids, endocrinology and metabolism, nutrition, obesity, and exercise physiology. They have contributed chapters that define a range of dietary approaches to reducing risk and associated chronic diseases. They begin by defining visceral obesity and its major outcomes; they also discuss the importance and the challenges of dietary approaches to reduce abdominal obesity, as compared to clinical approaches, with major costs and risks. Offers detailed, well-documented reviews outlining the various dietary approaches to visceral obesity with their benefits and failures Includes chapters on types of foods, exercise, and supplements in reducing obesity and its chronic clinical companions, especially diabetes and cardiovascular disease Helps nutritionists, dieticians, and healthcare providers approach patients in making decision about nutritional therapies and clinical treatments for abdominal obesity, from an evidence-based perspective
Download or read book Zebrafish in Development and Disease written by Gokhan Dalgin and published by Frontiers Media SA. This book was released on 2019-12-06 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are only a few vertebrate systems that can be used to model human diseases for biomedical discovery. The zebrafish model provides key advantages over existing models. Their externally developing embryos provide high-throughput non-invasive imaging, chemical screening, forward and reverse genetics, and their regeneration capacity make zebrafish a valuable system for novel discovery. Developmental studies using zebrafish has influenced discoveries in many human health-related conditions. This Research Topic covers all aspects of zebrafish studies, providing developmental mechanisms to human health conditions. The aim of the Research Topic was to foster a platform to bring all levels of zebrafish research including but not limited to development, disease, regeneration, drug screening, bioinformatics and Omics studies.
Download or read book Animal Models written by J.B. Owen and published by Springer Science & Business Media. This book was released on 2001-10-31 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with a novel aspect of a topical problem that is of widespread concern. Obesity and other eating disorders are significant human health problems that are proving highly resistant to prevention and cure. The recognition of important genotype/environment interaction in the causation of these problems and of the extensive genetic homology of higher animals justifies the importance of cross-species comparisons. The book covers observations made on animals in the wild as well as experimental data on laboratory animals and farm animals in order to lay out the basic genetic and environmental factors underlying the control of appetite (including diet selection) and body weight. Breakdown in these intricate mechanisms are then compared to examine the possible common candidate genes and their interaction with non-genetic factors, particularly the availability of diet choice and of levels of body activity. Animals have much to tell us about these mysteries and may significantly aid progress in dealing with what are still highly intractable and serious diseases of the modern world.
