Download or read book Telomeres and Telomerase written by Predrag Slijepcevic and published by S. Karger AG (Switzerland). This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Telomeres are essential functional elements of eukaryotic chromosomes. Their fundamental biological role as protectors of chromosome stability was identified for the first time in the 1930s by Hermann Muller and Barbara McClintock based on pioneering cytological experiments. Modern molecular research carried out more recently revealed that telomeres and telomerase play important roles in processes such as carcinogenesis and cellular senescence. This special issue presents the most recent developments in this highly active field of research. It is becoming increasingly clear that molecular pathways involved in regulation of telomere length and structure are functionally linked with pathways involved in DNA damage response, cellular stress response, chromatin organization and perhaps even pathways that regulate evolutionary chromosome rearrangements. The above functional link is explored by the leading experts in the field of telomere biology. Cell biologists, molecular biologists, oncologists, gerontologists, and radiobiologists with an interest in the role of telomeres/telomerase will appreciate the up-to-date information in this publication.

Download or read book High Field Magnetism written by M. Date and published by Elsevier. This book was released on 2012-12-02 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: High Field Magnetism presents the proceedings of the International Symposium on High Field Magnetism held at the Osaka University and Hotel Plaza in Osaka on September 13-14, 1982 as a satellite symposium of the International Conference on Magnetism-1982-Kyoto. The symposium tackled a wide variety of high field generation methods and material systems, with magnetism orientation as the main objective. A special Technical Exposition was held in the poster session where representatives from MIT, Grenoble, and other high field facilities were invited to give a descriptive review of each laboratory. This book is divided into eight parts, beginning with an introductory chapter into the subject of high field magnetism. The succeeding parts focus on magnetic interactions and phase transitions in high magnetic fields; metals and alloys in high magnetic fields; high field superconductivity; spin and charge fluctuations in high magnetic fields; high field magneto-optics; high field magnetic resonance; and high magnetic field facilities and techniques. This book will be of interest to practitioners in the fields of cryogenic engineering and applied physics.

Download or read book Learning Clinical Reasoning written by Jerome P. Kassirer and published by LWW. This book was released on 2010 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Employs a case-based approach to teach the basics of clinical reasoning, discusses steps in the clinical reasoning process, inductive and deductive strategies, data collection and its flaws, and assessing the reliability of clinical evidence.

Download or read book Eighteen Poems written by James Boyd and published by . This book was released on 1944 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nanotechnologies in Preventive and Regenerative Medicine written by Vuk Uskokovic and published by Elsevier. This book was released on 2017-10-30 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage Explains how nanomaterials can be manipulated to create more effective drug treatments Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments

Download or read book General Catalogue written by Bernard Quaritch and published by . This book was released on 1880 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Supermaterials written by Rudi Cloots and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is a supermaterial? A concise definition is by no means obvious, but a clue can be obtained from the topics discussed here.. In addition to superconductors, the reader will encounter magnetic effects of many kinds, including giant and even colossal ones, organic conductors, photoconductors, and even 400-year-old Japanese ceramics. Processing is a prominent pursuit in supermaterials research, especially but not exclusively of the superconductors. The papers on characterisation and theory break new ground, particularly in pursuit of new optoelectronic phenomena. The parade of new materials recently synthesised, often containing four or more elements, is surprising. But it is in it reporting of new applications that the book stands out: from circuits to sensors, supermaterials are making their impact on society.

Download or read book Theory Of Superconductivity written by J. Robert Schrieffer and published by CRC Press. This book was released on 2018-03-05 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theory of Superconductivity is primarily intended to serve as a background for reading the literature in which detailed applications of the microscopic theory of superconductivity are made to specific problems.

Download or read book Language Syntax and the Natural Sciences written by Ángel J. Gallego and published by Cambridge University Press. This book was released on 2018-10-18 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exploration of human language from the perspective of the natural sciences, this outstanding book brings together leading specialists to discuss the scientific connection of language to disciplines such as mathematics, physics, chemistry and biology.

Download or read book Cerebral Localization written by K.J. Zülch and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The demonstration of the basic brain mechanism through studying the partially commissure-sectioned case appears to be a most prom ising enterprise. The work with animals of HAMILTON and others in elucidating psychological brain process heretofore not imagined are mere indications of what the potential seems to be. Study of the partially disconnected patient seems equally revealing and productive in showing how many high level cognitive activities are managed in the cerebral flow of information. With respect to the issue of localization of function, it would seem clear that those cerebral areas clearly involved in the im mediate processing of raw sensory information can be selectively and specifically isolated and disconnected. In other words, the informational products of the long axonal type cells of Golgi, which MARCUS JACOBSON claims are the brain cells under strict genetic control, can be isolated, whereas the products of more complex and integrative mental activities which are managed by the more mutable Golgi type II cells do not seem to be so spec ifically disposed. Thus, these data suggest the lateralized spe cialities of the various left and right brain areas can make their contribution to the cerebral activities of the opposite hemisphere through almost any callosal area regardless of its size and loca tion. Indeed, this interpretation suggests to me that the long standing issue of the extent of localization could be better un derstood by considering the dichotomy in genetic specification as offered by HIRSCH and JACOBSON (1974).

Download or read book Philosophy of Cancer written by Marta Bertolaso and published by Springer. This book was released on 2016-08-24 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the 1970s, the origin of cancer is being explored from the point of view of the Somatic Mutation Theory (SMT), focusing on genetic mutations and clonal expansion of somatic cells. As cancer research expanded in several directions, the dominant focus on cells remained steady, but the classes of genes and the kinds of extra-genetic factors that were shown to have causal relevance in the onset of cancer multiplied. The wild heterogeneity of cancer-related mutations and phenotypes, along with the increasing complication of models, led to an oscillation between the hectic search of ‘the’ few key factors that cause cancer and the discouragement in face of a seeming ‘endless complexity’. To tame this complexity, cancer research started to avail itself of the tools that were being developed by Systems Biology. At the same time, anti-reductionist voices began claiming that cancer research was stuck in a sterile research paradigm. This alternative discourse even gave birth to an alternative theory: the Tissue Organization Field Theory (TOFT). A deeper philosophical analysis shows limits and possibilities of reductionist and anti-reductionist positions and of their polarization. This book demonstrates that a radical philosophical reflection is necessary to drive cancer research out of its impasses. At the very least, this will be a reflection on the assumptions of different kinds of cancer research, on the implications of what cancer research has been discovering over 40 years and more, on a view of scientific practice that is most able to make sense of the cognitive and social conflicts that are seen in the scientific community (and in its results), and, finally, on the nature of living entities with which we entertain this fascinating epistemological dance that we call scientific research. The proposed Dynamic and Relational View of carcinogenesis is a starting point in all these directions.

Download or read book The Future of Scientific Practice written by Marta Bertolaso and published by Routledge. This book was released on 2015-10-06 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on cell dynamics, molecular medicine and robotics, contributors explore the interplay between biological, technological and theoretical ways of thinking. The collection makes a strong contribution to current debates in the philosophy of science and the changing role of scientific practice.

Download or read book Political Economy and Sociolinguistics written by David Block and published by Bloomsbury Publishing. This book was released on 2018-02-08 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shortlisted for the BAAL Book Prize 2019 This book explores how political economy intersects with sociolinguistics, specifically how neoliberalism, inequality and social class mediate language in society issues. After the preface, in which the author sets the scene for the content of the book, Chapter 1 is an extensive, though selective, review of sociolinguistics research which has been framed as political economic in orientation. The chapter concludes that such research generally contains little in the way of thorough and in-depth coverage of the key ideas and conceptual frameworks said to undergird it. With this consideration in mind, Chapters 2, 3 and 4 are organised around in-depth discussions of, respectively, political economy as a general disciplinary frame; neoliberalism as the variegated variety of capitalism dominant in the world today; and stratification, inequality and social class, as phenomena intrinsic to capitalism, which in the neoliberal era have come to the fore as key issues. Drawing directly on the background provide in Chapters 2-4, Chapters 5 and 6 explore two distinct political economy-informed lines of research, on the one hand, the 'neoliberal citizen', and on the other hand, 'discursive class warfare'. The book ends with an epilogue addressing issues arising around political economy in sociolinguistics.

Download or read book Explaining Cancer written by Anya Plutynski and published by Oxford University Press. This book was released on 2018-07-18 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Explaining Cancer, Anya Plutynski addresses a variety of philosophical questions that arise in the context of cancer science and medicine. She begins with the following concerns: · How do scientists classify cancer? Do these classifications reflect nature's "joints"? · How do cancer scientists identify and classify early stage cancers? · What does it mean to say that cancer is a "genetic" disease? What role do genes play in "mechanisms for" cancer? · What are the most important environmental causes of cancer, and how do epidemiologists investigate these causes? · How exactly has our evolutionary history made us vulnerable to cancer? Explaining Cancer uses these questions as an entrée into a family of philosophical debates. It uses case studies of scientific practice to reframe philosophical debates about natural classification in science and medicine, the problem of drawing the line between disease and health, mechanistic reasoning in science, pragmatics and evidence, the roles of models and modeling in science, and the nature of scientific explanation.

Download or read book Organic Free Radicals written by William A. Pryor and published by . This book was released on 1978 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Hand written by Marta Bertolaso and published by Springer. This book was released on 2017-09-22 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on shared research experiences and collaborative projects, this book offers a broad and timely perspective on research on the hand and its current challenges. It especially emphasizes the interdisciplinary context in which researchers need to be trained in contemporary science. From language to psychology, from neurology to the social sciences, and from art to philosophy and religion, the chapters discuss various aspects involved in hand research and therapy. On the basis of concrete and validated case studies, they approach hand function and gestures from different perspectives – not only neurological and medical, but also philosophical, evolutionary and anthropological. By highlighting the overlaps between different areas of research, the book seeks to foster better communication between researchers, and ultimately a better understanding of hand function and its recovery. It offers essential information and inspirations for students, researchers and practitioners in the fields of psychology, epistemology, bioengineering, neuroscience, anthropology and bioethics.

Download or read book Aromatic Interactions written by Darren W. Johnson and published by Royal Society of Chemistry. This book was released on 2016-11-24 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of aromatic interactions, the fundamental nature of substituent effects and the identification of contacts between anions and aromatic systems have generated stimulating arguments in recent years. New theoretical frameworks have been developed and tested and aromatic interactions have emerged as potential solutions for varied problems in biology and materials science. This book provides a wide ranging survey of the latest findings and advances surrounding aromatic interactions, stretching from the fundamentals to modern applications in synthesis, biology and materials chemistry. It also discusses computational, experimental and analytical approaches to understanding these interactions, including pi-pi, anion-pi, and cation-pi interactions. Aromatic Interactions: Frontiers in Knowledge and Application is a useful text for advanced students and researchers, and appeals to those working within the fields of supramolecular chemistry, computational chemistry and thermodynamics.