Download or read book Dianion Chemistry in Organic Synthesis written by Charles M. Thompson and published by CRC Press. This book was released on 1994-08-19 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many laboratories were reluctant at first to embrace dianion chemistry as part of the standard reaction repertoire. Today, however, researchers can comfortably draw upon the dianion literature to choose an abundance of reagents and strategies that are reliable, effective, and, in many cases, the best answer to a synthetic problem. This interesting book introduces, surveys, and consolidates carbon-based dianion chemistry. Chapter 1 serves as an introduction and as an index of the various dianions covered in the book. Chapters 2 through 5 cover the ensemble of dianion types designated by their first deprotonation site. Each chapter contains an experimental section that explains relevant protocols.
Download or read book Side Reactions in Organic Synthesis written by Florencio Zaragoza Dörwald and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds. This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia. Contents: 1 Organic Synthesis: General Remarks 2 Stereoelectronic Effects and Reactivity 3 The Stability of Organic Compounds 4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles 5 The Alkylation of Carbanions 6 The Alkylation of Heteroatoms 7 The Acylation of Heteroatoms 8 Palladium-Catalyzed C-C Bond Formation 9 Cyclizations 10 Monofunctionalization of Symmetric Difunctional Substrates
Download or read book Lanthanides Chemistry and Use in Organic Synthesis written by Shu Kobayashi and published by Springer. This book was released on 2003-07-01 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Download or read book Modern Methods of Organic Synthesis written by W. Carruthers and published by Cambridge University Press. This book was released on 2004-10-14 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook on modern methods of organic synthesis.
Download or read book Art in Organic Synthesis written by Nitya Anand and published by Wiley-Interscience. This book was released on 1988-02-18 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than any other branch of organic chemistry, synthesis has improved our understanding of the structure, dynamics, and transition of molecules. The availability of sophisticated tools and new techniques has made organic synthesis more challenging than ever for those in the field. This updated edition of the 1970 work highlights significant and intriguing synthetic achievements: their ingenuity in design, extent of stereochemical control, new reactions, and new reagents. Approximately 100 examples illustrate various aspects of organic synthesis, with particular emphasis on bond-making and bond-breaking, dissymetry, conformation, and stereoelectric considerations. Each describes the synthesis of a natural product or of an unusual or strained molecule. Numerous flow sheets and perspective structural formulas illustrate the force of arguments predicting the stereochemical outcome of important steps. Also included is a type-transformation index which highlights some less common reactions.
Download or read book Compendium of Organic Synthetic Methods Volume 3 written by Louis S. Hegedus and published by John Wiley & Sons. This book was released on 2009-09-09 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compendium of Organic Synthetic Methods, Vols. I & II By Ian T.Harrison & Shuyen Harrison Volume I A complete one-volumecompilation of organic functional group transformations. Includes3000 synthetic methods presented in the form of reactions withleading references. Divided into sections corresponding to allpossible interconversions between the major functional groups:acetylene, carboxylic acid, alcohol, aldehyde, etc. Other partsdeal with the protection of carboxylic acids, alcohols, aldehydes,aminos, and ketones. 1971 529 pp. Volume II Presents thepreparations for all monofunctional compounds published between1971 and 1974, plus findings of earlier years to provide a valuablesupplement to Volume I. 1974 437 pp.
Download or read book Advanced Organic Chemistry written by Francis A. Carey and published by Springer. This book was released on 2006-05-02 with total page 969 pages. Available in PDF, EPUB and Kindle. Book excerpt: The control of reactivity to achieve specific syntheses is one of the overarching goals of organic chemistry. In the decade since the publication of the third edition, major advances have been made in the development of efficient new methods, particularly catalytic processes, and in means for control of reaction stereochemistry. This volume assumes a level of familiarity with structural and mechanistic concepts comparable to that in the companion volume, Part A, Structures and Mechanisms. Together, the two volumes are intended to provide the advanced undergraduate or beginning graduate student in chemistry with a sufficient foundation to comprehend and use the research literature in organic chemistry. The New Revised 5th Edition will be available shortly. For details, click on the link in the right-hand column.
Download or read book Strategies and Tactics in Organic Synthesis written by Michael Harmata and published by Academic Press. This book was released on 2012 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, this book vividly demonstrates through first hand accounts how synthesis is really done and how by discovering new reactions, creating new designs and building molecules with atom and step economies, the advancement of the science of organic synthesis is providing solutions through function to create a better world. Presents state-of-the-art developments in organic synthesisProvides insight and offers new perspective to problem-solvingWritten by leading experts in the field.
Download or read book Organozinc Reagents in Organic Synthesis written by Ender Erdik and published by CRC Press. This book was released on 2020-09-24 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organozinc reagents are used extensively in organic synthesis to find useful pathways to organic products. Illustrated and tabulated with over 950 equations, schemes, tables, and figures, Organozinc Reagents in Organic Synthesis provides an overall picture of the chemistry of organozinc compounds. Written by a professor of organic chemistry, the book familiarizes the reader with the reactions involving organozinc reagents that have general usefulness in synthesis. Emphasis is placed on preparation methods and reactivity of organozinc reagents. Reactions are summarized in equations and schemes, making it easy for you to see the characteristics of each type of reaction.
Download or read book Lewis Acids and Selectivity in Organic Synthesis written by M. Santelli and published by CRC Press. This book was released on 1995-11-21 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lewis acids provide inexpensive access to elaborated molecules obtained with high selectivities (regio-, stereo-, and enantioselectivity). Lewis Acids and Selectivity in Organic Synthesis is the first book to deal with these new and promising roles of Lewis acids. The book begins with general considerations on Lewis acids and a description of Lewis acid-carbonyl complexes, which are involved in most of the reactions described: ene reactions, allylsilane and allyltin addition to carbonyl compounds, addition of nucleophiles to acetals, conjugated addition of allylsilanes and allyltins to unsaturated carbonyl compounds (Sakurai reaction), and Diels-Alder reaction. Subsequent chapters examine these issue in detail, with special attention given to the way Lewis acids induce diastereo- and enantioselectivity. The extensive use of schemes (approximately 1000) ensures rapid visual uptake of the information. Lewis Acids and Selectivity in Organic Synthesis serves as a valuable source of information for all who face the challenge of selectivity in organic synthesis.
Download or read book Carbanion Chemistry written by E. Buncel and published by . This book was released on 2003 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Table of contents
Download or read book Chemical Approaches to the Synthesis of Peptides and Proteins written by Paul Lloyd-Williams and published by CRC Press. This book was released on 2020-08-18 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic chemists working on the synthesis of natural products have long found a special challenge in the preparation of peptides and proteins. However, more reliable, more efficient synthetic preparation methods have been developed in recent years. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.
Download or read book Anion Receptor Chemistry written by Jonathan L Sessler and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anion recognition plays a critical role in a range of biological processes, and a variety of receptors and carriers can be found throughout the natural world. Chemists working in the area of supramolecular chemistry have created a range of anion receptors, drawing inspiration from nature as well as their own inventive processes. This book traces the origins of anion recognition chemistry as a unique sub-field in supramolecular chemistry while illustrating the basic approaches currently being used to effect receptor design. The combination of biological overview and summary of current synthetic approaches provides a coverage that is both comprehensive and comprehensible. First, the authors detail the key design motifs that have been used to generate synthetic receptors and which are likely to provide the basis for further developments. They also highlight briefly some of the features that are present in naturally occurring anion recognition and transport systems and summarise the applications of anion recognition chemistry. Providing as it does a detailed review for practitioners in the field and a concise introduction to the topic for newcomers, Anion Receptor Chemistry reflects the current state of the art. Fully referenced and illustrated in colour, it is a welcome addition to the literature.
Download or read book Sulphones in Organic Synthesis written by N S. Simpkins and published by Elsevier. This book was released on 2013-10-22 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last twenty years the use of sulphones in organic synthesis has increased dramatically, the synthetic repertoire of sulphones having been developed to such an extent as to rival the carbonyl functionality for versatility. Not only have sulphones been employed in a great many synthetic methodologies, enabling the preparation of a vast array of functionalised products, but the sulphone group has also proved to be of enormous value in many of the most demanding and sophisticated total syntheses carried out in recent years. This book describes in detail all of the important sulphone chemistry employed in organic synthesis, ranging from the well-established sulphone-mediated methods to less familiar sulphone reactions and very recent discoveries of synthetic potential.
Download or read book Organic Syntheses Volume 84 written by Marvin J. Miller and published by John Wiley & Sons. This book was released on 2007-10-08 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Syntheses: Volume 84 continues the tradition of providing significant and interesting procedures, which should prove worthwhile to many synthetic chemists working in increasingly diverse areas.
Download or read book Activated Metals in Organic Synthesis written by P. Cintas and published by CRC Press. This book was released on 2020-01-29 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Activated Metals in Organic Synthesis discusses fundamental principles of the generation of activated, highly reactive metals, and their applications in organic synthesis. Following an introductory chapter on basic forms of metals the chapters in Part 1 are devoted to common strategies utilized for the preparation of active metals. These strategies include vaporization and subsequent co-condensation of metal atoms, in addition to depassivating methods employed commonly in laboratory syntheses. Chapters in Part 2 discuss relevant organic transformations in which metal activation plays a crucial role. Specific topics covered include metal-induced reductive methods; pinacolic, Reformatsky-, and Barbier-type reactions; McMurry ketone-olefin coupling; and the Bernet-Vasella reaction. Each chapter is followed by literature citations ranging from specific references to significant reviews. Many structural formulas are provided, making it easy to follow each synthesis. The book will be an important reference for students, organic chemists, and researchers in all areas of organometallic chemistry.
Download or read book Modern NMR Techniques for Synthetic Chemistry written by Julie Fisher and published by CRC Press. This book was released on 2014-10-13 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: A blend of theory and practical advice, Modern NMR Techniques for Synthetic Chemistry illustrates how NMR spectroscopy can be used to determine the abundance, size, shape, and function of organic molecules. It provides you with a description the NMR technique used (more pictorial than mathematical), indicating the most common pulse sequences, some practical information as appropriate, followed by illustrative examples. This format is followed for each chapter so you can skip the more theoretical details if the practical aspects are what interest you. Following a discussion of basic parameters, the book describes the utility of NMR in detecting and quantifying dynamic processes, with particular emphasis on the usefulness of saturation-transfer (STD) techniques. It details pulsed–field gradient approaches to diffusion measurement, diffusion models, and approaches to ‘inorganic’ nuclei detection, important as many synthetic pathways to new organics involve heavier elements. The text concludes with coverage of applications of NMR to the analysis of complex mixtures, natural products, carbohydrates, and nucleic acids—all areas of activity for researchers working at the chemistry-life sciences interface. The book’s unique format provides some theoretical insight into the NMR technique used, indicating the most common pulse sequences. The book draws upon several NMR methods that are resurging or currently hot in the field and indicates the specific pulse sequence used by various spectrometer manufacturers for each technique. It examines the analysis of complex mixtures, a feature not found in most books on this topic.
