Download or read book Diagnosis and Management of Endocrine related Tumors written by Richard J. Santen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients with a variety of tumors present to the physician because of clinical manifestations of hormones secreted in excess. This phenomenon attracted the investigative interest of such pioneers as Harvey Cushing who recognized that pituitary tumors may cause acromegaly and Charles Mayo who associated hyper tension with adrenal medullary neoplasms. Current int~rest in endocrine-related tumors has intensified because of the explosive development of newer methodol ogy for their study. Specific measurements of secretory products, hybridization assays to identify products of genomic translation and quantitative assessment of tissue hormone receptors have provided means of characterizing and precisely following patients with endocrine-related tumors. Treatments based upon these advances are rapidly proliferating. The current volume attempts to synthesize much of this recent information with the goal of providing a sound basis for making clinical judgements regarding diagnosis and management. Tumors of endocrine glandular tissues commonly confront practicing physi cians with difficult management problems. Several unique features of these tumors necessitate collaboration among various specialty disciplines in order to resolve these problems and to provide a high level of clinical care. For example, endocrine neoplasms secrete active hormones or hormone precursors which produce clinical manifestations most familiar to endocrinologists. Certain thera pies such as radioactive iodine for thyroid cancer take advantage of the hormone responsiveness of these tumors to facilitate treatment. These aspects require individuals trained in endocrinology to implement complex diagnostic and thera peutic maneuvers.
Download or read book The Human Hypothalamus written by Dick F. Swaab and published by Elsevier. This book was released on 2021-07-04 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume summarizes the role of the hypothalamus in neuroendocrine disorders, identifying the mechanism of action, disorder etiology, and best practices for assessment and treatment. Disorders covered include pituitary hypothalamic disorders of development and growth, hypothalamic tumor related disorders, hypothalamic autoimmune disorders and infection, disorders of vasopressin, water and sodium homeostasis, eating disorders, and gonadotropic hormone regulation disorders. Discusses the importance of the hypothalamus in human growth and development Reviews hypothalamic related tumors, as well as pituitary, autoimmune, vasopressin and hormone regulation disorders Includes metabolic and eating disorders Identifies mechanisms of disease action and etiology Provides best practice information for assessment and treatment
Download or read book Pancreatic Cancer Cystic Neoplasms and Endocrine Tumors written by Hans G. Beger and published by John Wiley & Sons. This book was released on 2015-04-27 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatic Cancer, Cystic Neoplasms and Endocrine Tumors: Diagnosis and Management is a modern, expertly crafted and clinically focused guide to the diagnosis, management and best-practice care of patients suffering from pancreatic cancer, cystic neoplasms and endocrine tumours. Packed with outstanding figures and with reference to the leading society guidelines, its main focus is on the many endoscopic and radiologic diagnostic techniques, medical and surgical management of both full-blown cancer and other tumors, and the risks of each form of treatment. Also covered in detail are issues of tumor recurrence and long-term outcome of treatment. Brought to you by highly skilled national and international leaders in the specialty and an experienced editor team, this is an invaluable guide to practicing gastroenterologists and surgeons in the hospital and clinical environment, as well as oncologists and endocrinologists managing patients with pancreatic tumorous lesions.
Download or read book Neuroendocrine Neoplasia Management written by Giordano Beretta and published by Springer Nature. This book was released on 2021-07-16 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most recent update on the management of neuroendocrine neoplasia (NEN), a term covering all tumors of various organs and/or with a particular histology, including MEN (multiple endocrine neoplasia) related tumors, MiNEN (mixed neuroendocrine-non-neuroendocrine neoplasms), NEC (neuroendocrine carcinoma) and Merkel’s carcinoma. NENs are heterogeneous in their biology, clinical presentation and prognosis, showing a great variability in aggressiveness and therapy response. As a result, their treatment is based on a large spectrum of options. The standard therapies are surgery in early disease, various loco-regional procedures in certain conditions and mostly of a palliative nature in metastatic disease. At present, thanks to our increased understanding of molecular signaling pathways, several pharmacological approaches can be used in patients with advanced NENs. Somatostatin analogs display both anti-tumor effects and symptom control. Novel peptide-radio-receptor treatment (PRRT) is used in patients with well differentiated tumors. The agents targeting angiogenesis and/or PI3K/AKT/mTOR pathway, alone or in combination with analogues, have provided encouraging results in advanced disease. The first part of the book focuses on the history, epidemiology and the most relevant scientific achievements, covering the discoveries in genetic and molecular biology, the endoscopic techniques with guided biopsy, and the metabolic imaging with hybrid PET/CT and MRI/CT. It particularly highlights the emerging strategies in therapy, surgery and mini-invasive surgery as well as loco-regional and systemic treatments, including targeted therapy and/or biological therapies. The second part then explores the management of NENs of various anatomical origins and/or with peculiar biology. It describes the range of the current options and the most relevant results from the clinical trials. This informative book provides valuable insights for all those interested in the management of neuroendocrine neoplasia.
Download or read book Diagnosis and Management of Endocrine Disorders in Interventional Radiology written by Hyeon Yu and published by Springer Nature. This book was released on 2022-01-01 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive guide for selective venous sampling procedures and the role of interventional radiologists in the care and treatment of patients with endocrine disorders. Disorders of the endocrine system involve an imbalance in the natural homeostasis of the hormones produced by the glands in the body. There are a variety of endocrine conditions that are characterized by either hormonal hyposecretion or hypersecretion. Percutaneous selective venous sampling is the gold standard diagnostic tool for the medical and surgical management of patients with a variety of such disorders. Selective venous sampling is a minimally invasive interventional procedure that interventional radiologists perform to localize sites of abnormal hormone secretion. Computed tomography and magnetic resonance imaging are the most used diagnostic imaging modalities in patients with the suspected endocrine disorder; however, their specificity is not optimal, and identifying a culprit gland is difficult based on imaging findings alone. Therefore, the ultimate decision for management depends on the outcome of selective venous sampling. As these various venous samplings are increasingly performed worldwide, the collaboration between interventional radiology, endocrinology, surgical endocrinology, surgical oncology, neurosurgery, and gynecology teams is essential. With limited literature on the topic, this volume fills the gap with in-depth coverage of selective venous sampling alongside the pathophysiology, epidemiology, clinical diagnosis, as well as medical, surgical, and interventional management of endocrine disorders. The book is divided into five parts: Clinical, Laboratory, and Radiological Diagnosis of Endocrine Disorders; Selective Venous Sampling in Interventional Radiology; Medical Treatment of Endocrine Disorders; Surgical Treatment of Endocrine Disorders; Interventional Treatment of Endocrine Disorders. Throughout these parts, endocrine disorders that require venous sampling are covered in depth: primary aldosteronism, primary hyperparathyroidism, Cushing’s disease, hormone-secreting pancreatic adenomas, and androgen-secreting ovarian tumors. There is additionally an emerging role for interventional management in thyroid gland disorders, which is covered here. This is an ideal guide for interventional radiologists caring for patients with endocrine disorders, as well as endocrinologists, endocrine surgeons, surgical oncologists, otolaryngologists, neurosurgeons, gynecologists, and nephrologists.
Download or read book Gigantism and Acromegaly written by Constantine A. Stratakis and published by Academic Press. This book was released on 2021-06-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism
Download or read book Diagnosis and Management of Pituitary Tumors written by Kamal Thapar and published by Springer Science & Business Media. This book was released on 2000-11-09 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eminent clinicians and specialists thoroughly review in great detail every aspect of pituitary tumors. The topics covered include prolactinomas, somatotroph adenomas, corticotroph adenomas, thyrotroph adenomas, nonfunctioning tumors, pituitary tumors, invasive adenomas, and pituitary carcinomas, as well as lesions, exclusive of pituitary adenomas, that occur in the sellar region. Also discussed are the new methods in endocrine diagnosis, high resolution imaging, receptor-mediated pharmacotherapy, microsurgical techniques, improved methods of radiation delivery, and the development of a precise and physiologically meaningful classification of pituitary tumors. Much-needed and brilliantly multidisciplinary, Diagnosis and Management of Pituitary Tumors offers all those dealing with pituitary cancer patients today's most comprehensive guide to diagnosis and treatment, one whose coordinated treatment strategies have sharply improved long-term survival rates for many patients.
Download or read book Endocrine Neoplasia written by Cord Sturgeon and published by Springer Science & Business Media. This book was released on 2009-12-03 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Neoplasia is a comprehensive, updated, and clearly-written text covering the diseases for which endocrine surgical expertise is often needed. We look towards advances in the science and the art of endocrine surgery to continuously improve outcomes for our patients. The goal of this text was to provide a detailed description of both the underlying science of disease as well as the art of clinical management. The book is divided into five sections addressing neoplasms of the thyroid, parathyroid, adrenal gland, neuroendocrine pancreas, and multiple endocrine neoplasia. Experts from the United States, Canada, and Australia have contributed chapters addressing both the biology of endocrine tumors and the clinical management of disease. Recent discoveries regarding the genetic underpinnings of disease are highlighted. Updated consensus guidelines were used for clinical recommendations. The management of complex and often confusing clinical problems is discussed in detail.
Download or read book Early Diagnosis and Treatment of Endocrine Disorders written by Robert S. Bar and published by Springer Science & Business Media. This book was released on 2003-04-08 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most endocrine diseases can be treated successfully, and the patient's state of well-being can usually be improved. Not surprisingly, the earlier the diagnosis is made the more positive the clinical response. Early Diagnosis and Treatment (~f Endocrine Disorders focuses on early signs and symptoms of endocrine disorders and surveys the appropriate tests to document the diseases as well as current recommendations for therapy. Each chapterreviews the pathophysiology of the endocrine disease-important for understanding each disorder as well as the rationale for early therapy-and the basis for the early recognition and treatment of each condition. Although the practicing endocrinologist is likely to be quite knowledgeable regarding many of these diseases, Early Diagnosis and Treatment of Endocrine Disorders includes treatment of those conditions only recently classified as endocrine disorders, such as polycystic ovarian syndrome, obesity, and hypogonadism. The book also provides new approaches that are urgently needed to slow the epidemic of type 2 diabetes, which should be an overriding concern for all clinicians. Until now, no other endocrinology text has focused primarily on the details of early recognition and therapy of endocrine disorders. The information in Early Diagnosis and Treatment of Endocrine Disorders is presented in an orderly and easy-to-follow manner, which should greatly facilitate the early recognition of endocrine diseases by medical students, house staff, primary care physicians, and endocrinologists, the four groups of clinical personnel to which this book is specificall y directed.
Download or read book Endocrine Tumors An Issue of Surgical Oncology Clinics of North America written by Douglas L Fraker and published by Elsevier Health Sciences. This book was released on 2016-01-19 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Douglas L. Fraker, is devoted to Endocrine Tumors. Dr. Fraker has assembled expert authors to review the following topics: Management of thyroid nodular disease: Current cytopathology classifications and genetic testing; Surgical management of lymph node compartments in papillary thyroid cancer; Current guidelines for post-operative treatment and follow-up of well differentiated thyroid cancer; Outpatient thyroid surgery – is it safe?; Asymptomatic hyperparathyroidism- diagnostic pitfalls and surgical intervention; Intra-operative PTH monitoring: optimal utilization; Minimally invasive parathyroidectomy vs bilateral neck exploration for primary hyperparathyroidism; Pheochromocytoma and paraganglioma: Diagnosis, genetics, and treatment; Minimally invasive adrenalectomy; Treatment of adrenocortical cancinoma: benefits of aggressive surgery; Biochemical diagnosis and pre-operative imaging of gastro-intestinal neuroendocrine tumors; Minimally invasive techniques for resection of pancreatic neuroendocrine tumors; and Treatment of metastatic neuroendocrine tumors to the liver.
Download or read book Epidemiology of Endocrine Tumors written by Jahangir Moini and published by Elsevier. This book was released on 2021-03-03 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology of Endocrine Tumors brings current data and clinical research into one source for a multidisciplinary audience. The book discusses the prevalence, incidence, etiology, pathology, diagnosis and treatment of various endocrine tumors. With clear and focused writing, it is essential reading for healthcare professionals, endocrinologists, oncologists, and public health professionals. Users will be able to bridge the knowledge gap that exists in the comprehensive coverage surrounding the epidemiology of endocrine tumors. Globally, the prevalence and incidence of endocrine tumors is high. This audience needs a treatise where they can gain a broad overview of endocrine tumors with a focus on epidemiology. Supplies information about the epidemiology of various endocrine tumors, both benign and malignant, to endocrinologists, oncologists and related health care professionals Focuses on the impact upon costs and patient deaths due to complications of these tumors Describes how endocrine tumors affect various age groups and ethnicities, discussing the prevention of endocrine tumors Presents chapters on Cancer Problem, Specific Endocrine Tumors, Prevention, Detection and Diagnosis, and Treatment of Endocrine Tumors Provides review questions with an answer key and detailed glossary
Download or read book Advances in Treatment and Management in Surgical Endocrinology written by Alexander L. Shifrin and published by Elsevier Health Sciences. This book was released on 2019-06-11 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date and evidence-based, Updates on Treatment and Management of Endocrinopathies [correct title?] provides an overview of recent developments regarding the most prevalent endocrine disorders. A concise, easy-to-read reference for endocrinologists and endocrine surgeons, this timely reference includes an overview of each disorder as well as diagnosis, management, treatment, prognosis, and a summary by a renowned expert who has contributed to the most current literature. Addresses endocrine diseases of the thyroid, parathyroid, and adrenal glands as well as familial endocrine syndromes: multiple endocrine neoplasia type 1 and 2 (MEN). Includes both surgical and nonsurgical treatments. Consolidates today's available information on this timely topic into one convenient resource.
Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endocrine Disorders Diagnosis and Management written by Trever Quinn and published by American Medical Publishers. This book was released on 2021-11-16 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The disorders related to the endocrine system are known as endocrine disorders. The specialty of medicine that is associated with the endocrine system is known as endocrinology. It is divided into three groups such as endocrine gland hyposecretion that leads to hormone deficiency, endocrine gland hypersecretion that leads to hormone excess and tumors of endocrine glands. Some of the common endocrine disorders are glucose homeostasis disorders, thyroid disorders, calcium homeostasis disorders, pituitary gland disorder, sex-hormone disorder, etc. Endocrine disease is categorized by misregulated hormone release, lack of a gland, structural enlargement in thyroid and inappropriate response to signaling. These diseases can be diagnosed with the help of blood tests and ultrasound. The management of these diseases includes a healthy diet, exercise, weight loss, use of medications and therapy. This book unravels the recent studies in the field of endocrine disorders. It covers in detail some existent theories and innovative concepts revolving around this domain. The extensive content of this book provides the readers with a thorough understanding of the subject.
Download or read book Gastrointestinal Endocrine Tumors written by and published by . This book was released on 1987 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neuroendocrine Tumours written by Suayib Yalcin and published by Springer. This book was released on 2015-05-27 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a timely textbook that covers all aspects of neuroendocrine tumors (NET) from epidemiology, pathological classification and evaluation and molecular biology through to diagnostic imaging methods and therapeutic options, including the latest targeted therapies. The various types of NET are individually discussed, including carcinoid tumors, insulinomas, gastrinomas, glucagonomas, VIPomas, somatostatinomas, PPomas, medullary thyroid carcinomas, adrenocortical cancer, pheochromocytomas, paragangliomas and non-functioning pancreatic NETs. The contributing authors are internationally recognized experts who bring a wealth of experience to the subject. This book will be an invaluable source of information for practicing medical oncologists, surgeons, endocrinologists, gastroenterologists and pathologists and also trainees.
Download or read book Thyroid Cancer written by Giorgio Grani and published by Springer. This book was released on 2021-12-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition utilizing brand new clinical case material, this popular, user-friendly text presents the diagnosis and treatment of thyroid cancer and related clinical issues, providing clinicians in endocrinology and oncology with the best real-world strategies to properly manage the various manifestations of thyroid cancer that they may encounter. Each chapter is a case report that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and therapy, as well as the case outcome, literature review, clinical pearls and pitfalls, and bibliography. All recommendations are based on evidence-based clinical practice guidelines and recent literature. Written by experts in the field, these cases illustrate treatment for both low- and high-risk differentiated thyroid cancer, including surgical approaches, radioiodine therapy, and novel chemotherapies and targeted therapies, as well as postoperative follow-up and special issues. Additional cases demonstrate the management of medullary thyroid cancer and anaplastic thyroid cancer. Topics new to the second edition include information on management of small thyroid cancers with “active surveillance” (without surgery), new chemotherapeutic approaches to advanced thyroid cancer, and new information on a lesion that is no longer considered to be thyroid cancer (Neoplastic Follicular Thyroid Neoplasm with Papillary-Like Features [NIFTP]), as well as material on external beam radiotherapy and new approaches to the management of anaplastic thyroid cancer. Pragmatic and reader-friendly, this second edition of Thyroid Cancer: A Case-Based Approach will be an excellent resource for clinical endocrinologists and oncologists, endocrine fellows, residents and students alike.