Download or read book Developmental Stages in the Rhesus Monkey Macaca mulatta written by A.A.M. Gribnau and published by Springer. This book was released on 1981 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decennia nonhuman primates have been increasingly used for research purposes in various scientific fields. Much interest has been focused on this group of animals in general and on the rhesus monkey in particular because of its close phylo genetic relationship with man. In some fields of research, however, such as embryology and microscopic anatomy, much less attention has been paid to nonhuman primates, probably because of the expense involved in the collection of the extensive material needed. On the other hand, teratological and experimental embryologic studies must be based upon a thorough knowledge of the normal ontogenesis since only in that way can a reliable distinction be made between normal and abnormal or induced develop ment. Each ontogenetic study essentially consists of a comparison of different deve lopmental stages. In most reports dealing with the development of individual organs or their subunits the material used is classified according to the estimated age or the length of the embryos. These criteria, however, are not valid, since considerable varia tion in developmental stage occurs between animals of the same age even between littermates and between animals of the same length. Therefore a method is needed for assigning embryos to successive developmental stages that are defmed on the basis of extemal and internal characteristics. This type of classification was elaborated by Stree ter (1942, 1945, 1948,1951), who arranged human embryos into developmental hori zons numbered XI through XXIII.
Download or read book Developmental Stages in the Rhesus Monkey Macaca Mulatta written by A. A. M. Gribnau and published by . This book was released on 2014-08-15 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structure Function Correlation on Rat Kidney written by Agnes Antoinette Marie Gribnau and published by . This book was released on 1981 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Veterinary Anatomy and Physiology written by and published by BoD – Books on Demand. This book was released on 2019-03-13 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of veterinary anatomy and physiology is essential for veterinary professionals and researchers. The chapters reflect the diverse and dynamic research being undertaken in a variety of different species throughout the world. Whether the animals have roles in food security, agriculture, or as companion, wild, or working animals, the lessons we learn impact on many areas of the profession. This book highlights research ranging from the cardiovascular and musculoskeletal systems, prostate and hoof, through to histopathology, imaging, and molecular techniques. It investigates both healthy and pathological conditions at differing stages of life. The importance of each cell and tissue through to the whole organism is explored alongside the methodologies used to understand these vital structures and functions.
Download or read book The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment written by Joerg Bluemel and published by Academic Press. This book was released on 2015-03-13 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area. - Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more - Includes practical examples on techniques and methods to guide your daily practice - Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes
Download or read book Nonhuman Primates in Biomedical Research written by Christian R. Abee and published by Academic Press. This book was released on 2012-06-07 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. - Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research - Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information - Includes four color images throughout
Download or read book A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates written by Kadharbatcha S. Saleem and published by Academic Press. This book was released on 2012-04-23 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates, Second Edition maps the detailed architectonic subdivisions of the cortical and subcortical areas in the macaque monkey brain using high-resolution magnetic resonance (MR) images and the corresponding histology sections in the same animal. This edition of the atlas is unlike anything else available as it includes the detailed cyto- and chemoarchitectonic delineations of the brain areas in all three planes of sections (horizontal, coronal, and sagittal) that are derived from the same animal. This is a significant progress because in functional imaging studies, such as fMRI, both the horizontal and sagittal planes of sections are often the preferred planes given that multiple functionally active regions can be visualized simultaneously in a single horizontal or sagittal section. This combined MRI and histology atlas is designed to provide an easy-to-use reference for anatomical and physiological studies in macaque monkeys, and in functional-imaging studies in human and non-human primates using fMRI and PET. The first rhesus monkey brain atlas with horizontal, coronal, and sagittal planes of sections, derived from the same animal Shows the first detailed delineations of the cortical and subcortical areas in horizontal, coronal, and sagittal plane of sections in the same animal using different staining methods Horizonal series illustrates the dorsoventral extent of the left hemisphere in 47 horizontal MRI and photomicrographic sections matched with 47 detailed diagrams (Chapter 3) Coronal series presents the full rostrocaudal extent of the right hemisphere in 76 coronal MRI and photomicrographic sections, with 76 corresponding drawings (Chapter 4) Sagittal series shows the complete mediolateral extent of the left hemisphere in 30 sagittal MRI sections, with 30 corresponding drawings (Chapter 5). The sagittal series also illustrates the location of different fiber tracts in the white matter Individual variability - provides selected cortical and subcortical areas in three-dimensional MRI (horizontal, coronal, and sagittal MRI planes). For comparison, it also provides similar areas in coronal MRI section in six other monkeys. (Chapter 6) Vasculature - indicates the corresponding location of all major blood vessels in horizontal, coronal, and sagittal series of sections Provides updated information on the cortical and subcortical areas, such as architectonic areas and nomenclature, with references, in chapter 2 Provides the sterotaxic grid derived from the in-vivo MR image
Download or read book Postnatal Development of the Human Hippocampal Formation written by Ricardo Insausti and published by Springer Science & Business Media. This book was released on 2010 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The postnatal development of the human hippocampal formation (HF) is subject of increasing interest due to its implication in important pathologies that hamper the normal development of children. In this work, the authors present a glimpse of the main events that constitute important milestones in the development and shaping of some of the most important psychological capabilities such as autobiographical memory. Although they examined some cases in the last trimester of gestation, their description starts at birth, around 40 gestational weeks. Serial sections with thionin for Nissl analysis revealed that all fields of the HF were present and identifiable at birth. However, the relative growth of the cortical mantle was much higher relative to the HF. The main structural changes took place during the first postnatal year, in particular in the dentate gyrus and in the entorhinal cortex. At subsequent ages, a growth in size was noted in all components of the HF. This growth was more evident at the body and tail of the hippocampus, as evidenced by measurements of the neuroanatomical series. In addition, the authors examined in some cases the MRI appearance of the HF at different postnatal ages obtained by post-mortem imaging. MRI neuroanatomical series provided anatomically identified landmarks useful for the MRI identification of different components of the HF during postnatal development.
Download or read book Developmental Staging in the Cynomolgus Monkey Macaca Fascicularis with Emphasis on the Metanephros written by Cruz Gonzalez Rodriguez and published by . This book was released on 1985 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Atlas for Staging Mammalian and Chick Embryos written by H. Butler and published by CRC Press. This book was released on 2018-02-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the convenience of research workers, particularly those with limited knowledge of embryology, we have put together a series of tables to enable rapid identification of specific stages of embryonic development in the more commonly used mammals. Because if its frequent usage the chick embryo is included this atlas.
Download or read book The Baboon in Biomedical Research written by John L. VandeBerg and published by Springer Science & Business Media. This book was released on 2009-06-04 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonhuman primates have played critical roles in biomedical research, and they are among the few animals whose use in research continues to increase. The scienti?c value of nonhuman primates derives from their close phylogenetic proximity to man and their consequent anatomic, physiologic, and genetic similarities to man. Only nonhuman primates can provide adequate models for many complex physiological and disease processes of humans. The baboon is a relative newcomer to the repertoire of nonhuman primates used in biomedical research. However, in less than 50 years since its ?rst use in the U. S. , it has become one of the most popular laboratory primate species. It is larger than the other widely used monkey species, making it advantageous for many types of experiments and technological developments. It is extraordinarily hardy and highly fecund in captivity. It closely resembles humans in a variety of physiological and disease processes, such as cholesterol metabolism, early stages of atherosclerosis, and alcoholic liver disease. Its chromosomes closely resemble those of humans, and many genes of the two species lie in the same chromosomal order. Among all primates, baboons are the most widely used models for the genetics of susceptibility to complex diseases and they are the ?rst nonhuman primate for which a framework genetic linkage map was established. In addition, the baboon genome is currently being sequenced, and as a result the utility of this species for biomedical research will be dramatically increased.
Download or read book Early Development of the Human Pelvic Diaphragm written by Wijnand F.R.M. Koch and published by Springer Science & Business Media. This book was released on 2007-06-05 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: A sound and detailed knowledge of the anatomy of the pelvic floor is of the utmost importance to gynecologists, obstetricians, surgeons, and urologists, since they all share the same responsibility in treating patients with different pathological conditions caused by pelvic floor dysfunction. The most common clinical expressions of pelvic floor dysfunction are urinary incontinence, anal incontinence, and pelvic organ prolapse. Most often these clinical expressions are found in women, and they are briefly discussed below based on the outline presented in the Third International Consultation on Incontinence, a joint effort of the International Continence Society and the World Health Organization. Established potential risk factors are age, childbearing, and obesity. The pelvic floor plays an important role in these risk factors. There is evidence that the pelvic floor structures change with age, giving rise to dysfunction. Pregnancy, and especially vaginal delivery, may result in pelvic floor laxity as a consequence of weakening, stretching, and even laceration of the muscles and connective tissue, or due to damage to pudendal and pelvic nerves. Comparable to pregnancy, obesity causes chronic strain, stretching, and weakening of muscles, nerves, and other structures of the pelvic floor.
Download or read book Patterns of Human Growth written by Barry Bogin and published by Cambridge University Press. This book was released on 1999-05-06 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: A revised edition of an established text on human growth and development from an anthropological and evolutionary perspective.
Download or read book The Monkeys of Stormy Mountain written by Jean-Baptiste Leca and published by Cambridge University Press. This book was released on 2012-01-19 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews the most important topics in current primatology using research on the long-studied Arashiyama population of Japanese macaques.
Download or read book Clinical Neuroembryology written by Hans J. ten Donkelaar and published by Springer Science & Business Media. This book was released on 2006-09-07 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in developmental neurobiology and advances in (neuro) genetics have been spectacular. The high resolution of modern imaging techniques applicable to developmental disorders of the human brain and spinal cord have created a novel insight into the developmental history of the central nervous system (CNS). This book provides a comprehensive overview of the development of the human CNS in the context of its many developmental disorders. It provides a unique combination of data from human embryology, animal research and developmental neuropathology, and there are more than 400 figures in over a hundred separate illustrations.
Download or read book Skeletal Anatomy of the Newborn Primate written by Timothy D. Smith and published by Cambridge University Press. This book was released on 2020-05-28 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first clearly-illustrated, comparative book on developmental primate skeletal anatomy, focused on the highly informative newborn stage.
Download or read book Nonhuman Primate Models For Human Diseases written by W. Richard Dukelow and published by CRC Press. This book was released on 2018-02-06 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: While research has enabled us to better understand the nonhuman primates, they have repaid that by repaid that by providing medical scientists with important tools for the study of human biomedical problems. This book is about those research tools. The book was designed by identifying areas of human medical research that are under intensive research study today. Authors were then selected based on their expertise at using nonhuman primates as models for the human condition. Each was asked to use as comparative an approach as models for the human condition. Each was asked to use a comparative an approach as possible, to provide the reader with knowledge relating to the usefulness of various nonhuman primate species to each specific research area.
