Download or read book Developmental Nephrology from Embryology to Metabolomics written by Vassilios Fanos and published by Hygeia Press. This book was released on 2012-06-19 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The traditional approach to kidney disorders is changing. In the field of diagnostics much innovative research is ongoing: from the “old” embryology, revisited and re-interpreted with new eyes in the light of immunohistochemistry, up to metabolomics the latest “daughter” of genomics, the most promising and remarkable of the “omics” disciplines. Between these two extremes we find a universe of novelties, ranging from the most recent urinary biomarkers to the questions of nutrition and growth, as well as those of ethics, which the new populations of extremely low birth weight (ELBW) neonates present to neonatologists and nephrologists. The studies on perinatal programming expands the temporal horizon of precocious reduction in the number of nephrons, both congenital and/or acquired, thus dilating and multiplying the immediate and long-term negative effects. Neonatal asphyxia, obstructive uropathies, nephrotoxic drugs administered to the mother and/or to the neonate, malnutrition, underfeeding, or overfeeding make it necessary to apply all possible preventive measures to ensure the well-being of the kidney. Because of the kidney’s holistic dimension, themethodical and rigorous study of neonatal nephrology has advanced all aspects of health through the life cycle. This volume is an update state of the art of the latest discoveries in neonatal and pediatric nephrology. These advances will have an even greater impact when the same children reach adulthood, and the ultimate consequences of perinatal care are unmasked.

Download or read book Kidney Development in Renal Pathology written by Gavino Faa and published by Springer. This book was released on 2014-08-09 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis. The book reviews new data on the effects on kidney development by neonatal asphyxia, obstructive uropathies, nephrotoxic drugs, malnutrition, underfeeding, overfeeding and provides all possible preventive measures to ensure the well-being of the kidney at birth. The book also discusses the possible implications between renal development and the insurgence of kidney disease in adult life and the correlation with renal carcinogenesis. Written by well recognized experts in their fields, Kidney Development in Renal Pathology is a valuable tool for pathologists, neonatologists, nephrologists, gynecologists and researchers with an interest in kidney diseases.

Download or read book Metabonomics and Gut Microbiota in Nutrition and Disease written by Sunil Kochhar and published by Springer. This book was released on 2014-10-21 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also examines the translatability of systems biology approaches into applied clinical research and to patient health and nutrition. The rise in multifactorial disorders, the lack of understanding of the molecular processes at play and the needs for disease prediction in asymptomatic conditions are some of the many questions that system biology approaches are well suited to address. Achieving this goal lies in our ability to model and understand the complex web of interactions between genetics, metabolism, environmental factors and gut microbiota. Being the most densely populated microbial ecosystem on earth, gut microbiota co-evolved as a key component of human biology, essentially extending the physiological definition of humans. Major advances in microbiome research have shown that the contribution of the intestinal microbiota to the overall health status of the host has been so far underestimated. Human host gut microbial interaction is one of the most significant human health considerations of the present day with relevance for both prevention of disease via microbiota-oriented environmental protection as well as strategies for new therapeutic approaches using microbiota as targets and/or biomarkers. In many aspects, humans are not a complete and fully healthy organism without their appropriate microbiological components. Increasingly, scientific evidence identifies gut microbiota as a key biological interface between human genetics and environmental conditions encompassing nutrition. Microbiota dysbiosis or variation in metabolic activity has been associated with metabolic deregulation (e.g. obesity, inflammatory bowel disease), disease risk factor (e.g. coronary heart disease) and even the aetiology of various pathologies (e.g. autism, cancer), although causal role into impaired metabolism still needs to be established. Metabonomics and Gut Microbiota in Nutrition and Disease serves as a handbook for postgraduate students, researchers in life sciences or health sciences, scientists in academic and industrial environments working in application areas as diverse as health, disease, nutrition, microbial research and human clinical medicine.

Download or read book Advances in Clinical Chemistry written by and published by Academic Press. This book was released on 2012-10-22 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 58 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology. - Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology

Download or read book Neonatal and Pediatric Clinical Pharmacology An Issue of Pediatric Clinics written by John N van den Anker and published by Elsevier Health Sciences. This book was released on 2012-10-28 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for safe and effective use of medicines in children and WHO's initiative "Make Medicines Child Size" have boosted research and educational activities in the area of pediatric clinical drug research. This issue focuses on both general and specific aspects of neonatal and pediatric clinical pharmacology including ethics, pharmacogenomics, metabolomics, adverse drug reactions, pain medication, pulmonary hypertension and several other hot topics. The editors have been able to find outstanding authors for the different parts on neonatal and pediatric pharmacology.

Download or read book Children of the Mother Goddess History of Mediterranean Neonates written by Vassilios Fanos and published by Hygeia Press. This book was released on 2020-12-11 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The leading elements in this volume are the cultural representation of birth and the forms through which its narration and representation develop in the figurative arts, through historical references, mythological tales and legends, traditions, customs and habits. The influence of myth, language and artistic expression on our cultural representation of procreation is manifest, and this way of “narrating” birth resists even today, although it comes into conflict with a more scientific vision of pregnancy and childbirth. With this book we believe we have contributed to an in-depth examination of illness narratives, thus favouring the search for a convergence between medical language in the sector and the language of cultural experience so that evidence-based medicine does not clash with narrative-based medicine, but that the two languages come together towards a reciprocity that will strengthen the alliance between physician and patient.

Download or read book A Comprehensive Guide to Toxicology in Preclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2012-10-18 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. - Chapters written by world-renowned contributors who are experts in their fields - Includes the latest research in preclinical drug testing and international guidelines - Covers preclinical toxicology in small molecules and biologics in one single source

Download or read book Fetal Medicine E Book written by Pranav P Pandya and published by Elsevier Health Sciences. This book was released on 2019-02-09 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering pertinent basic science and offering today's most authoritative guidance on clinical management, Fetal Medicine, 3rd Edition, is a must-have resource for obstetricians and other healthcare professionals involved in care of the fetus. An international team of expert contributors delivers the knowledge and background you need to effectively diagnose and treat fetal disorders – everything from prenatal screening and diagnostic tests to common and rare prenatal conditions, early pregnancy loss, ethical issues, and much more. - Focuses on fetal medicine throughout, bringing you today's most reliable information in both basic science and clinical topics. - Offers updated information from cover to cover, including new coverage of genetics, embryology, and clinical management. - Features new self-assessment questions and new images throughout – for a total of nearly 1,000 photographs and line drawings, as well as more than 150 quick-reference tables. - Details fast-changing developments in fetal medicine, including advances in ultrasound imaging, cytogenetics, molecular biology, and biochemistry. - Helps you learn and retrieve complex information quickly thanks to succinct, highly structured text; key points at the beginning of each chapter; and concise chapter summaries. New editor team – 3 new editors with an international approach – they will select qualified authors who can discuss the basic science as well as the clinical aspects of perinatal problems Updated knowledge content – major areas of change are non-invasive prenatal testing (NIPT) and genetic testing – Ron Wapner is one of the leaders in these fields Expert Consult access – individual electronic access for the first time 4-color design – current design is b&w so will update with new colors and colorize the drawings.

Download or read book Live cell imaging Cell and developmental research bridging education optical engineering industry software shared facilities written by Michelle S. Itano and published by Frontiers Media SA. This book was released on 2023-04-28 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proceedings of 16th European Nephrology Conference 2017 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: October 02-03, 2017 Barcelona, Spain Key Topics : Nephrology, Etiology,Renal Pathology-Immunology, Kidney and Bladder Stones, Acute Kidney Injury, Chronic Kidney Diseases, End Stages Renal Diseases, Glomerular Disorders, Kidney cancer, Hypertension Associated with Kidney Diseases, Diabetic Nephropathy, Pediatric Nephrology, Clinical Nephrology, Treatment and Surgery for Renal Diseases, Dialysis and Renal Care, Diagnostic,Imaging and Radiation techniques, Kidney Transplantation, Renal Nutrition,Inflammation, and Metabolism, Drugs for Kidney Diseases, Nephrologists & Entrepreneurs Investment Meet, Urology/Urinary tract infections, Fluid, Electrolytes, and Acid-Base,

Download or read book Proceedings of 17th International Conference on Nephrology Urology 2018 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: March 12-13, 2018 London , UK Key Topics : New Updates in Hypertension, Nephrology and Kidney, Dialysis, Urinary Tract Infection, Kidney Transplantation, Pediatric Nephrology, Nephrology Nursing, Chronic Kidney Disease, Cardio Renal Failure, Diagnostic, imaging and radiation techniques, Kidney and Bladder stones, Clinical Nephrology, Surgery for Renal diseases, Hypertension Associated With Kidney Diseases, Renal Pathology-Immunology, Pediatric Nephrology, Nephrology Medicine,

Download or read book Methodologies for Metabolomics written by Norbert W. Lutz and published by Cambridge University Press. This book was released on 2013-01-21 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.

Download or read book Proceedings of 12th Global Nephrologists Annual Meeting 2017 written by ConferenceSeries and published by ConferenceSeries. This book was released on 2017-06-20 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: June 26-28, 2017 London, UK Key Topics : Nephrology, Diabetes-Diabetic Kidney Disease, Dialysis and Renal Care, Translational-Clinical Nephrology, Acute Kidney Injury (AKI), Kidney Transplantation, Chronic Kidney Disease (CKD), Kidney Cancer, Hypertension and Kidney Disease, Cardiovascular Impacts of Kidney Disease, Pediatric Nephrology, CKD -Mineral and Bone Disorders, Geriatric-Genetic Kidney Diseases, Renal Nutrition, Inflammation, and Metabolism, Treatment and Drugs for Kidney Diseases, Renal Pathology-Immunology, Nephrologists & Entrepreneurs Investment Meet, Kidney/Urology/Urinary Tract Infections, Glomerular-Tubulointerstitial Disorders, Kidney and Bladder stones, Fluid, Electrolytes, and Acid-Base,

Download or read book Proceedings of 19th Global Nephrologists Annual Meeting 2018 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: May 14-15, 2018 Rome, Italy Key Topics : Nephrology & Clinical Nephrology, Dialysis, Renal Nutrition, Kidney Transplantation, Hypertensive Associated Kidney Diseases, Kidney Diseases & Diagnosis of Kidney Diseases, Urology/Urinary tract infections, Pediatric Nephrology, Glomerular Disorders, Cardiovascular Impacts of Kidney Disease, Kidney and Bladder stones, Acute Kidney Injury, End Stage Renal diseases (or) Chronic Kidney Diseases, Kidney Cancer, Tubular and Interstitial Diseases, Renal Pathology-Immunology, Fluid, Electrolytes and Acid-Base, Diabetes-Diabetic Kidney Disease, New Updates in Hypertension, Nephrology and Kidney, Nephrologists & Entrepreneurs Investment Meet, Geriatric-Genetic Kidney Diseases and Onconephrology, Commercialization,

Download or read book Pediatric Nephrology written by Francesco Emma and published by Springer Nature. This book was released on 2022-09-01 with total page 2112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the course of the previous seven editions, Pediatric Nephrology has become the standard reference text for students, trainees, practicing physicians (pediatricians, nephrologists, internists, and urologists), subspecialists, and allied health professionals seeking information about children’s kidney diseases. It is global in perspective, reflecting the fact that the international group of editors are all acknowledged world experts. The latest edition of this text is no different, providing a comprehensive, state-of-the-art overview on pediatric nephrology. Much like the previous edition, the latest edition reviews the most critical aspects of the field. Topics covered include developmental physiology and diseases, renal physiology and diagnostic approaches, glomerular disease, kidney involvement in systemic diseases, renal tubular disorders, homeostasis, cystic kidney disease and related disorders, urinary tract disorders, hypertension, acute kidney injury, and chronic kidney failure. Unlike the previous edition, however, the chapters in this edition now combine physiology, clinical management, and pathology for ease of use. The latest edition also includes a new section on the evaluation of different disorders that can have multiple etiologies, setting the stage for the evaluation and management of specific diseases. This book serves as a superb resource and an invaluable asset for practitioners, health professionals, and trainees seeking out information about children's kidney diseases.

Download or read book Principles of Gender Specific Medicine written by Marianne Legato J and published by Academic Press. This book was released on 2023-04-03 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans.We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine. - Covers the most important developments in biomedical research in the past decade, with a thoughtful analysis of how they impact patient care - Discusses the feasibility and usefulness of personalized medicine, the limits and promise of genetic editing, the basis for variation in sexual identity and how artificial intelligence and technology will affect basic human function as well as correcting disability - Promotes and facilitates discussions about the ethics and governance issues that surround much of what science is now able to do at the most basic levels of human's physiology

Download or read book Molecular and Cellular Toxicology written by Lesley Stanley and published by John Wiley & Sons. This book was released on 2014-04-02 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology is the study of the adverse effects of chemical, physical, or biological agents on people, animals, and the environment. Toxicologists are trained to investigate, interpret, and communicate the nature of those effects. Over the last ten years the subject of toxicology has changed dramatically, moving from a discipline which was once firmly wedded to traditional methods to one which is keen to embrace the innovative techniques emerging from the developing fields of cell culture and molecular biology. There is an acute need for this to be reflected in a paradigm shift which takes advantage of the opportunities offered by modern developments in the life sciences, including new in vitro and in silico approaches, alternative whole organism (non-mammalian) models and the exploitation of ‘omics methods, high throughput screening (HTS) techniques and molecular imaging technologies. This concise, accessible introduction to the field includes the very latest concepts and methodologies. It provides MSc, PhD and final year undergraduate students in pharmacy, biomedical and life sciences, as well as individuals starting out in the cosmetics, consumer products, pharmaceutical and testing industries, with everything they need to know to get to grips with the fast moving field of toxicology and the current approaches used in the risk assessment of drugs and chemicals.