Download or read book Principles of Developmental Genetics written by Sally A. Moody and published by Elsevier. This book was released on 2007-07-19 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlike anything currently available in the market, Dr. Sally A. Moody and a team of world-renowned experts provide a groundbreaking view of developmental genetics that will influence scientific approaches in embryology, comparative biology, as well as the newly emerging fields of stem cell biology and regenerative medicine. Principles of Developmental Genetics highlights the intersection of developmental biology with new revolutionary genomic technologies, and details how these advances have accelerated our understanding of the molecular genetic processes that regulates development. This definitive resource provides researchers with the opportunity to gain important insights into the clinical applicability of emerging new technologies and animal model data. This book is a must-have for all researchers in genetics, developmental biology, regenerative medicine, and stem cell biology.• Includes new research not previously published in any other book on the molecular geneticprocesses that regulates development• Chapters present a broad understanding on the application of animal model systems, allowingresearchers to better treat clinical disorders and comprehend human development• Relates the application of new technologies to the manipulation of stem cells, causes ofhuman birth defects, and several human disease conditions• Each chapter includes a bulleted summary highlighting clinical aspects of animal models

Download or read book Developmental Genetics and Plant Evolution written by Quentin C.B. Cronk and published by CRC Press. This book was released on 2004-01-29 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: A benchmark text, Developmental Genetics and Plant Evolution integrates the recent revolution in the molecular-developmental genetics of plants with mainstream evolutionary thought. It reflects the increasing cooperation between strongly genomics-influenced researchers, with their strong grasp of technology, and evolutionary morphogenetists and sys

Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Download or read book Origination of Organismal Form written by Gerd B. Muller and published by MIT Press. This book was released on 2003-01-03 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A more comprehensive version of evolutionary theory that focuses as much on the origin of biological form as on its diversification. The field of evolutionary biology arose from the desire to understand the origin and diversity of biological forms. In recent years, however, evolutionary genetics, with its focus on the modification and inheritance of presumed genetic programs, has all but overwhelmed other aspects of evolutionary biology. This has led to the neglect of the study of the generative origins of biological form. Drawing on work from developmental biology, paleontology, developmental and population genetics, cancer research, physics, and theoretical biology, this book explores the multiple factors responsible for the origination of biological form. It examines the essential problems of morphological evolution—why, for example, the basic body plans of nearly all metazoans arose within a relatively short time span, why similar morphological design motifs appear in phylogenetically independent lineages, and how new structural elements are added to the body plan of a given phylogenetic lineage. It also examines discordances between genetic and phenotypic change, the physical determinants of morphogenesis, and the role of epigenetic processes in evolution. The book discusses these and other topics within the framework of evolutionary developmental biology, a new research agenda that concerns the interaction of development and evolution in the generation of biological form. By placing epigenetic processes, rather than gene sequence and gene expression changes, at the center of morphological origination, this book points the way to a more comprehensive theory of evolution.

Download or read book The Genetics and Development of Scoliosis written by Kenro Kusumi and published by Springer Science & Business Media. This book was released on 2009-12-15 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental genetic studies of the spine and linkage and family-based association studies have led to recent advances in understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. The book is written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine.

Download or read book Petunia written by Tom Gerats and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Petunia belongs to the family of the Solanaceae and as such is closely related to important crop species like tomato, potato, eggplant, pepper and tobacco. With around 35 species described it is one of the smaller genera and among those there are two groups of species that make up the majority of them: the purple flowered P.integrifolia group and the white flowered P.axillaris group. It is assumed that interspecific hybrids between members of these two groups have laid the foundation for the huge variation in cultivars as selected from the 1830’s onwards. Petunia thus has been a commercially important ornamental since the early days of horticulture. Despite that, Petunia was in use as a research model only parsimoniously until the late fifties of the last century. By then seed companies started to fund academic research, initially with the main aim to develop new color varieties. Besides a moment of glory around 1980 (being elected a promising model system, just prior to the Arabidopsis boom), Petunia has long been a system in the shadow. Up to the early eighties no more then five groups developed classical and biochemical genetics, almost exclusively on flower color genes. Then from the early eighties onward, interest has slowly been growing and nowadays some 20-25 academic groups around the world are using Petunia as their main model system for a variety of research purposes, while a number of smaller and larger companies are developing further new varieties. At present the system is gaining credibility for a number of reasons, a very important one being that it is now generally realized that only comparative biology will reveal the real roots of evolutionary development of processes like pollination syndromes, floral development, scent emission, seed survival strategies and the like. As a system to work with, Petunia combines advantages from several other model species: it is easy to grow, sets abundant seeds, while self- and cross pollination is easy; its lifecycle is four months from seed to seed; plants can be grown very densely, in 1 cm2 plugs and can be rescued easily upon flowering, which makes even huge selection plots easy to handle. Its flowers (and indeed leaves) are relatively large and thus obtaining biochemical samples is no problem. Moreover, transformation and regeneration from leaf disc or protoplast are long established and easy-to-perform procedures. On top of this easiness in culture, Petunia harbors an endogenous, very active transposable element system, which is being used to great advantage in both forward and reverse genetics screens. The virtues of Petunia as a model system have only partly been highlighted. In a first monograph, edited by K. Sink and published in 1984, the emphasis was mainly on taxonomy, morphology, classical and biochemical genetics, cytogenetics, physiology and a number of topical subjects. At that time, little molecular data was available. Taking into account that that first monograph will be offered electronically as a supplement in this upcoming edition, we would like to put the overall emphasis for the second edition on molecular developments and on comparative issues. To this end we propose the underneath set up, where chapters will be brief and topical. Each chapter will present the historical setting of its subject, the comparison with other systems (if available) and the unique progress as made in Petunia. We expect that the second edition of the Petunia monograph will draw a broad readership both in academia and industry and hope that it will contribute to a further expansion in research on this wonderful Solanaceae.

Download or read book Developmental Genetics written by Gurbachan S. Miglani and published by I. K. International Pvt Ltd. This book was released on 2013-12-30 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development is behind what one looks like. It is directed by genes, the units of heredity, which are made up to deoxyribonucleic acid (DNA) in all animals (including man), plants, microorganisms and most of the viruses except in some viruses where ribonucleic acid (RNA) is the genetic material. Developmental Genetics integrates the two disciplines of development and genetics into one. Key Features: Each chapter begins with a brief introduction and historical background. The text explains both classical and recent material. Various phenomena of developmental genetics explained with examples of animals, plant, bacteria and viruses. Text explained with suitable examples, illustrations, tables and figures. List of references and review questions given at the end of each chapter Exhaustive glossary, author index and subject index given at the end of the book. This book is essential reading for postgraduate in developmental genetics, teachers teaching this subject and developmental biologists conducting research in this area. It is also suitable for candidates preparing for ARS/UGC NET examination.

Download or read book Developmental Biology written by Norman John Berrill and published by . This book was released on 1971 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genomic Control Process written by Isabelle S. Peter and published by Academic Press. This book was released on 2015-01-21 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development. - Covers a vast area of current biological research to produce a genome oriented regulatory bioscience of animal life - Places gene regulation, embryonic and postembryonic development, and evolution of the body plan in a unified conceptual framework - Provides the conceptual keys to interpret a broad developmental and evolutionary landscape with precise experimental illustrations drawn from contemporary literature - Includes a range of material, from developmental phenomenology to quantitative and logic models, from phylogenetics to the molecular biology of gene regulation, from animal models of all kinds to evidence of every relevant type - Demonstrates the causal power of system-level understanding of genomic control process - Conceptually organizes a constellation of complex and diverse biological phenomena - Investigates fundamental developmental control system logic in diverse circumstances and expresses these in conceptual models - Explores mechanistic evolutionary processes, illuminating the evolutionary consequences of developmental control systems as they are encoded in the genome

Download or read book Molecular Genetics of Plant Development written by Stephen Herbert Howell and published by Cambridge University Press. This book was released on 1998-07-13 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to present classical plant development in modern, molecular-genetic terms. The study of plant development is rapidly changing as plant genome projects uncover a multitude of new genes. This book provides a framework for integrating gene discovery and genome analysis into the context of plant development. Molecular Genetics of Plant Development is designed to be used as a text-book for upper-division or graduate courses in plant development. The book will also serve as a reference book for scientists in the field of plant molecular biology or plant molecular genetics. The book is also useful for general development courses in which both animal and plant development are presented.

Download or read book Misbehaving Science written by Aaron Panofsky and published by University of Chicago Press. This book was released on 2014-07-07 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavior genetics has always been a breeding ground for controversies. From the “criminal chromosome” to the “gay gene,” claims about the influence of genes like these have led to often vitriolic national debates about race, class, and inequality. Many behavior geneticists have encountered accusations of racism and have had their scientific authority and credibility questioned, ruining reputations, and threatening their access to coveted resources. In Misbehaving Science, Aaron Panofsky traces the field of behavior genetics back to its origins in the 1950s, telling the story through close looks at five major controversies. In the process, Panofsky argues that persistent, ungovernable controversy in behavior genetics is due to the broken hierarchies within the field. All authority and scientific norms are questioned, while the absence of unanimously accepted methods and theories leaves a foundationless field, where disorder is ongoing. Critics charge behavior geneticists with political motivations; champions say they merely follow the data where they lead. But Panofsky shows how pragmatic coping with repeated controversies drives their scientific actions. Ironically, behavior geneticists’ struggles for scientific authority and efforts to deal with the threats to their legitimacy and autonomy have made controversy inevitable—and in some ways essential—to the study of behavior genetics.

Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Gene Expression to Neurobiology and Behaviour written by Oliver Braddick and published by Elsevier. This book was released on 2011-09-26 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: How does the genome, interacting with the multi-faceted environment, translate into the development by which the human brain achieves its astonishing, adaptive array of cognitive and behavioral capacities? Why and how does this process sometimes lead to neurodevelopmental disorders with a major, lifelong personal and social impact? This volume of Progress in Brain Research links findings on the structural development of the human brain, the expression of genes in behavioral and cognitive phenotypes, environmental effects on brain development, and developmental processes in perception, action, attention, cognitive control, social cognition, and language, in an attempt to answer these questions. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Download or read book A History of Genetics written by Alfred Henry Sturtevant and published by CSHL Press. This book was released on 2001 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the small “Fly Room†at Columbia University, T.H. Morgan and his students, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written in 1965 by one of those present at the beginning. His account is one of the few authoritative, analytic works on the early history of genetics. This attractive reprint is accompanied by a website, http://www.esp.org/books/sturt/history/ offering full-text versions of the key papers discussed in the book, including the world's first genetic map.

Download or read book The Genetics of Neurodevelopmental Disorders written by Kevin J. Mitchell and published by John Wiley & Sons. This book was released on 2015-09-28 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pathogenic mutations, which are grouped here based on the neurodevelopmental processes impacted. Subsequent chapters consider the use of cellular and animal models to elucidate the cascading consequences of such mutations, from molecular and cellular levels to emergent effects on neural circuits, brain systems and subsequent psychological development. The text concludes by examining the important clinical implications of the recent advances in the field, from recognition of the genetic causes in individual patients to development of new treatments and interventions. A timely synthesis, The Genetics of Neurodevelopmental Disorders is a unique and essential resource for neuroscientists, geneticists, neurologists and psychiatrists and an accessible and up-to-date overview for medical and science students.

Download or read book The Concept of the Gene in Development and Evolution written by Peter J. Beurton and published by Cambridge University Press. This book was released on 2000-05-29 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biological research in the latter half of the twentieth century have made the story of the gene vastly complicated: the more we learn about genes, the less sure we are of what a gene really is. Knowledge about the structure and functioning of genes abounds, but the gene has also become curiously intangible. This collection of essays renews the question: what are genes? Philosophers, historians and working scientists re-evaluate the question in this volume, treating the gene as a focal point of interdisciplinary and international research. It will be of interest to professionals and students in the philosophy and history of science, genetics and molecular biology.