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Book Developmental Epilepsy  From Clinical Medicine To Neurobiological Mechanisms

Download or read book Developmental Epilepsy From Clinical Medicine To Neurobiological Mechanisms written by Carl E Stafstrom and published by World Scientific. This book was released on 2019-06-24 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'It is a small treasure chest of information presented in a compact textbook format. The unique contribution of this volume is the authors' ability to seamlessly bridge our current understanding of the basic science and genetics of this group of disorders to the clinical aspects of each epilepsy ... In short, those who practice in the field of epilepsy will find this text an easily accessible mini encyclopedia of reviews of our current understanding of the mechanisms that underlie the various childhood epilepsies. Readers will appreciate the digestible length and level of detail of each chapter and enjoy grabbing this book off the shelf.'Journal of Paediatric Epilepsy This is a collection of chapters from renowned authors focused on the contemporary issues in developmental epilepsy, from both clinical and basic science perspectives. Developmental epilepsy (or epilepsy syndromes), while receiving much more attention than 20 years ago, is still not well understood. This lag in research is reflected in the challenges of treating developmental epilepsy. The book discusses these challenges in the clinic and brings them back to the laboratory bench (and in some cases back to the bedside). This book fills a gap in the literature on developing epilepsy by bridging current clinical knowledge with basic and translational research in the developing brain relevant for developmental epilepsy.The book is introduced by a chapter on brain development to provide a background for understanding when and how seizures and epilepsy can emerge. Recent clinical research indicates strong relationship between childhood epilepsy and developmental cognitive impairment. This connection can be studied in experimental animals and can uncover developmental mechanisms common to both conditions. Targeting those mechanisms might reveal disease-modifying treatments. Febrile seizures are very common in the pediatric population and their impact on further epilepsy development is explored. The link between immunity, inflammation and epileptogenesis in the developing brain is explored. Many developmental epilepsies arise from brain malformations or neuronal migration deficits; some juvenile epilepsies have a clear genetic basis while the etiology of others is less certain. Recently, the involvement of the mTOR pathway in certain childhood epilepsy syndromes was recognized, prompting the repurposing of drugs used in cancer treatment for therapy of these specific epilepsy syndromes. Steroid hormones have significant hormonal effects on neurotransmitter receptors and function, and therefore have an impact on childhood epilepsy; sex steroids may have long term organizational effects on brain structure and epilepsy development. Stress, even early in development, may affect the developing brain and lead to behavioral changes as well as increased susceptibility to seizures.

Book Epilepsy Across the Spectrum

    Book Details:
  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release : 2012-07-29
  • ISBN : 0309259533
  • Pages : 568 pages

Download or read book Epilepsy Across the Spectrum written by Institute of Medicine and published by National Academies Press. This book was released on 2012-07-29 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although epilepsy is one of the nation's most common neurological disorders, public understanding of it is limited. Many people do not know the causes of epilepsy or what they should do if they see someone having a seizure. Epilepsy is a complex spectrum of disorders that affects an estimated 2.2 million Americans in a variety of ways, and is characterized by unpredictable seizures that differ in type, cause, and severity. Yet living with epilepsy is about much more than just seizures; the disorder is often defined in practical terms, such as challenges in school, uncertainties about social situations and employment, limitations on driving, and questions about independent living. The Institute of Medicine was asked to examine the public health dimensions of the epilepsies, focusing on public health surveillance and data collection; population and public health research; health policy, health care, and human services; and education for people with the disorder and their families, health care providers, and the public. In Epilepsy Across the Spectrum, the IOM makes recommendations ranging from the expansion of collaborative epilepsy surveillance efforts, to the coordination of public awareness efforts, to the engagement of people with epilepsy and their families in education, dissemination, and advocacy for improved care and services. Taking action across multiple dimensions will improve the lives of people with epilepsy and their families. The realistic, feasible, and action-oriented recommendations in this report can help enable short- and long-term improvements for people with epilepsy. For all epilepsy organizations and advocates, local, state, and federal agencies, researchers, health care professionals, people with epilepsy, as well as the public, Epilepsy Across the Spectrum is an essential resource.

Book Jasper s Basic Mechanisms of the Epilepsies

Download or read book Jasper s Basic Mechanisms of the Epilepsies written by Jeffrey L. Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Book The Epilepsies

    Book Details:
  • Author : Chrysostomos P. Panayiotopoulos
  • Publisher : Springer
  • Release : 2005
  • ISBN :
  • Pages : 570 pages

Download or read book The Epilepsies written by Chrysostomos P. Panayiotopoulos and published by Springer. This book was released on 2005 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.

Book Indexes to the Epilepsy Accessions of the Epilepsy Information System

Download or read book Indexes to the Epilepsy Accessions of the Epilepsy Information System written by J. Kiffin Penry and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Causes of Epilepsy

    Book Details:
  • Author : Simon Shorvon
  • Publisher : Cambridge University Press
  • Release : 2019-05-02
  • ISBN : 1108420753
  • Pages : 1013 pages

Download or read book The Causes of Epilepsy written by Simon Shorvon and published by Cambridge University Press. This book was released on 2019-05-02 with total page 1013 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.

Book Epilepsy in Children and Adolescents

Download or read book Epilepsy in Children and Adolescents written by James W. Wheless and published by John Wiley & Sons. This book was released on 2012-10-22 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy in childhood presents a profound challenge Epilepsy is an unsettling, complex condition. There is no ‘one size fits all’ option. For effective treatment a full understanding of each patient’s situation and clinical history is needed. Recent remarkable improvements in our ability to image brain structures, to define physiological patterns and in treatment options has made the task of care of the child with epilepsy potentially more effective. Epilepsy in Children and Adolescents provides the contemporary, caring guidance you need to diagnose and manage seizures in a young patient. Beginning with an overview of the classification of epilepsy syndromes, the experienced authors cover: Diagnostic evaluation of childhood epilepsies Principles of treatment Generalized seizures and generalized epilepsy syndromes Partial onset seizures and localization-related epilepsy syndromes Epilepsies relative to age, etiology or duration The full range of treatment options: medical, dietary, surgical Epilepsy in Children and Adolescents takes a practical approach to a common but complex clinical challenge.

Book Developmental Epilepsy

Download or read book Developmental Epilepsy written by Carl Ernest Stafstrom and published by . This book was released on 2019 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Epileptic Syndromes in Infancy  Childhood and Adolescence   5th edition

Download or read book Epileptic Syndromes in Infancy Childhood and Adolescence 5th edition written by Bureau Michelle and published by John Libbey Eurotext. This book was released on 2012-11-12 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ultimate reference book : the 5th updated edition of the famous “blue guide”. Incluided : A DVD with new sequences completes each chapter! Epileptology changes. The syndromic approach is completed by an etiological approach, based on the major advances in genetics and functional genetics. New entities have found their place, and a purely descriptive, “electroclinical” approach is no longer adapted in many circumstances. The 5th edition of the Blue Guide includes the most recent advances. It was necessary to justify the physiological, epidemiologic, genetic and therapeutic approaches and to consider them in the light of the new classification efforts, which are still in the making. Nevertheless, the description of epileptic syndromes, both classical and recent, remains at the core of this book.

Book Epilepsy in Children  2E

    Book Details:
  • Author : Sheila J Wallace
  • Publisher : CRC Press
  • Release : 2004-02-27
  • ISBN : 0340808144
  • Pages : 535 pages

Download or read book Epilepsy in Children 2E written by Sheila J Wallace and published by CRC Press. This book was released on 2004-02-27 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy is the most common neurological disorder of childhood, occurring both in children whose physical and cognitive states are otherwise normal as well as being a facet of a more generalised and severe brain disease. There are many manifestations of epilepsy and, therefore, a diversity of factors in underlying pathology, responses to treatment and prognosis. Full understanding requires knowledge of the basic science that underlies epilepsy and its causes, and an appreciation of cognitive, psychiatric and social factors. This book is a comprehensive and up-to-date review of all aspects of childhood epilepsy for the specialist neurologist or paediatrician with an interest in this area. The first edition was praised for its valuable clinical approach to examining the nature of epileptic syndromes and for its appropriate and readable coverage of the underlying basic science, features that are retained and expanded upon in this revision. Particular updates include full coverage of new developments in epidemiology, genetics, classification, imaging, drug therapy and other treatments. Several new chapters have been added, covering eyelid myoclonia, Rasmussen's syndrome, cognitive and behavioural manifestations of epilepsy, and vagal nerve stimulation. This book is essential reading for paediatric neurologists, epileptologists and paediatricians, and will continue to provide invaluable support for any physician confronted by a child with epilepsy.

Book Photosensitive Epilepsy

    Book Details:
  • Author : Graham F. A. Harding
  • Publisher : Cambridge University Press
  • Release : 1994-01-10
  • ISBN : 9781898683025
  • Pages : 204 pages

Download or read book Photosensitive Epilepsy written by Graham F. A. Harding and published by Cambridge University Press. This book was released on 1994-01-10 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photosensitive epilepsy is a relatively rare condition in which convulsions are precipitated by visual stimuli. The authors have spent almost 30 years studying this condition and have assembled the largest cohort of patients ever studied by one centre. Their previous book on the subject (1975) became the standard text on this condition. This book reviews the earlier studies, reviews all the literature on this condition in humans and details the many studies that have since been carried out, including studies on drug therapy, the long term prognosis for the condition, pattern sensitivity, video game epilepsy, and convulsions precipitated by other video material. In addition there is advice on procedures to reduce the risk of stimulation from television as well as such factors as the genetics of photosensitivity. This is the most comprehensive text available.

Book Oxford Textbook of Epilepsy and Epileptic Seizures

Download or read book Oxford Textbook of Epilepsy and Epileptic Seizures written by Samden Lhatoo and published by Oxford University Press. This book was released on 2013 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures, and is complemented by an online edition.

Book Growing Up with Epilepsy

Download or read book Growing Up with Epilepsy written by Lynn Bennett Blackburn, PhD and published by Demos Medical Publishing. This book was released on 2003-06-01 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the tools you need to raise a child with epilepsy, to support his/her social development, provide effective discipline, and negotiate the educational system. Each stage in your child's life presents unique issues and problems, ranging from finding day care to school programming to driving. This book is organized so that you can go to the information that you need when you need it, returning for updates as your child grows and new issues emerge. In her 20 years of working with children with epilepsy, Dr. Blackburn has been continually impressed by the fact that no two children with epilepsy are the same. Each child and each family has unique needs. Because of this, she works with a team. The unique talents of each team member let the group meet the unique needs of each patient. This book will help you build the resource team for your child. In addition to providing you with basic tools, the book identifies resources, places you can contact, additional materials you can read, and the kinds of professionals that may be in your community to help you and your child. Every parent is busy, and parents of children with epilepsy may be evenbusier than most. This book has been organized with the busy parent in mind. The first four chapters are a "must read" for every parent. Theyprovide the basic tools for understanding epilepsy, behavior management and school programming. The final chapter summarizes parenting of a child with epilepsy, providing an easy to remember checklist. Issues for parenting a toddler with epilepsy are far different than issuesfor parenting an adolescent. You can go to the information that you need,when you need it, returning to the book for an update as your child grows and new issues emerge. You can select the section that is important to you in understanding your child, reading the other chapters when you have time and/or want to know more about the brain in general. Childhood epilepsy may provide speed-bumps in the road to adulthood, but it does not have to be a barricade. For 20 years, Dr. Blackburn has helped parents negotiate the speed bumps, creating an owner's manual for their child. Now, she helps you make this journey.

Book Epilepsy and Neurodevelopmental Diseases

Download or read book Epilepsy and Neurodevelopmental Diseases written by Eleonora Palma and published by Frontiers Media SA. This book was released on 2020-12-09 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This topic has been realized in collaboration with Dr. Gabriele Ruffolo, Post Doctoral Researcher at the University of Rome (Sapienza) (ORCID ID: 0000-0002-6554-5496).

Book Childhood Epilepsy

    Book Details:
  • Author : William B. Svoboda
  • Publisher : Cambridge University Press
  • Release : 2004-03-04
  • ISBN : 1139449885
  • Pages : 676 pages

Download or read book Childhood Epilepsy written by William B. Svoboda and published by Cambridge University Press. This book was released on 2004-03-04 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than half the numbers of children with epilepsy have interrelated language, learning and/or behavior complications. By adulthood, these problems can interfere with socialization and employment. The seizures may be controlled but the developmental distortions can continue to present problems for health and education systems and carers. In this comprehensive and fully referenced book, William Svoboda distils a lifetime of clinical experience with childhood epilepsy into three areas which address each of the main areas of difficulty. In each he looks at why the problems arise and assesses diagnostic and remediative approaches. The focus is on the whole care of the child rather than on diagnosis, classification and medication alone. Clinicians, mental health practitioners, educators and speech–language pathologists will find this book invaluable.

Book Epilepsy in Children

    Book Details:
  • Author : Erin Conway, MS, RN, CPNP
  • Publisher : Springer Publishing Company
  • Release : 2015-12-02
  • ISBN : 1617052361
  • Pages : 288 pages

Download or read book Epilepsy in Children written by Erin Conway, MS, RN, CPNP and published by Springer Publishing Company. This book was released on 2015-12-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the parent of a child with epilepsy, an easy-to-read guide to understanding and managing the disorder while helping your child achieve and maintain a high quality of life. From a leading neurologist, experienced nurse practitioner, and registered dietician comes the complete guide to managing your childís life with epilepsy. Epilepsy in Children offers the practical advice and information you need to manage your childís seizures safely and effectively, understand the latest treatment options, and find hope for a seizure-free future. Key Features: Get the right diagnosis for your child and the correct treatment to reduce the frequency of seizures faster Learn the benefits and risks of pharmaceutical, surgical, and alternative therapies including the ketogenic diet Help your child maintain a normal life at school, with friends, and in sports and other activities Navigate the transitions from infancy and childhood, to puberty, to becoming a young adult

Book Epilepsy and Your Child

Download or read book Epilepsy and Your Child written by Richard Appleton and published by Class Publishing Ltd. This book was released on 2004 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: A question and answer reference book for parents whose children have epilepsy.