Download or read book Development of Molecular Subtyping Databases to Improve Control of Listeria Monocytogenes written by Eric Brandon Fugett and published by . This book was released on 2006 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Listeria monocytogenes is a foodborne pathogen that can cause a serious foodborne disease, listeriosis, which may result in abortion, meningitis, and septicemia. The high hospitalization and mortality rates of listeriosis warrant continued research efforts to reduce the transmission of L. monocytogenes to humans. Molecular subtyping techniques, which can be used to differentiate bacteria beyond the species level, facilitate the identification and tracking of L. monocytogenes subtypes throughout the food chain. Pulsed-field gel electrophoresis is a rapid and highly discriminatory molecular subtyping method currently used by public health and regulatory agencies to identify and track outbreaks of foodborne disease and link outbreak related cases to suspected vehicles. Although PFGE facilitated outbreak recognition and response has been successful in reducing the number of listeriosis associated fatalities, additional large-scale analysis of subtype data is needed to develop a better understanding of L. monocytogenes ecology and further reduce the incidence of foodborne listeriosis. To this end, we subtyped 495 L. monocytogenes isolates from human clinical cases, foods, ruminant farms, and urban and natural environments using two-enzyme (AscI and ApaI) PFGE to better understand L. monocytogenes PFGE type diversity and distribution. We found that while L. monocytogenes is a genetically diverse organism, nine PFGE types were significantly associated with certain sources, and two PFGE types were specific to a single processing facility each. Conversely, nine PFGE types were geographically widespread and isolated from multiple sources, indicating that large molecular subtyping databases are necessary to facilitate epidemiological investigations by identifying the distribution patterns of PFGE types that cause outbreaks. To meet this need, we developed PathogenTracker, a publicly available molecular subtyping database that will facilitate storage and large-scale analysis of different L. monocytogenes subtype data. Data in PathogenTracker can be queried through a variety of options, including DNA sequence and banding pattern-based searches (e.g., ribotype, PFGE type). This database also allows for the creation of individualized summary tables and permits simple statistical analysis of summary table data. Currently populated with subtype data for over 6,000 L. monocytogenes isolates, PathogenTracker will facilitate more rapid listeriosis outbreak detection and source tracking, development of a better understanding of L. monocytogenes transmission and ecology, and definition of specific characteristics for L. monocytogenes subtypes isolated from different sources populations. We also developed a freely available standard L. monocytogenes reference strain collection, organized into a diversity set (25 isolates representing 25 PFGE types) and an outbreak set (21 isolates representing nine listeriosis outbreaks), which has not been previously available. In combination with inclusion of these isolates in PathogenTracker, which includes continuously updated information on strain characteristics and peer-reviewed references that utilized specific isolates, this strain collection provides a unique resource that will aid efforts to further improve our ability to reduce human foodborne listeriosis through development of improved diagnostic procedures and intervention strategies. In addition, this strain collection provides a unique resource for basic and applied studies on the physiology, ecology, evolution, and pathogenesis of L. monocytogenes. (Abstract).
Download or read book DNA Sequence based Subtyping and Molecular Evolution of Listeria and Listeria Monocytogenes written by Steven Cai and published by . This book was released on 2002 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Agriculture Rural Development Food and Drug Administration and Related Agencies Appropriations for 2007 Research education and economic programs written by United States. Congress. House. Committee on Appropriations. Subcommittee on Agriculture, Rural Development, Food and Drug Administration, and Related Agencies and published by . This book was released on 2006 with total page 1732 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book 107 2 Hearings Agriculture Rural Development Food and Drug Administration and Related Agencies Appropriations for 2003 Part 4 February 28 2002 written by and published by . This book was released on 2002 with total page 1678 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Listeria Monocytogenes written by Dongyou Liu and published by CRC Press. This book was released on 2008-04-21 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Once feared as a deadly intracellular bacterium with the extraordinary capacity to survive a wide array of arduous external stressors, Listeria monocytogenes is increasingly recognized as a preferred vector for delivering anti-infective and anti-cancer vaccine molecules. A reliable, single-source reference on the fundamental aspects of
Download or read book Emerging Infectious Diseases written by and published by . This book was released on 2001 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Agriculture Rural Development and Related Agencies Appropriations for Fiscal Year 2002 written by United States. Congress. Senate. Committee on Appropriations. Subcommittee on Agriculture, Rural Development, and Related Agencies and published by . This book was released on 2002 with total page 986 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book DNA Methods in Food Safety written by Omar A. Oyarzabal and published by John Wiley & Sons. This book was released on 2014-08-21 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular typing of foodborne pathogens has become an indispensable tool in epidemiological studies. Thanks to these techniques, we now have a better understanding of the distribution and appearance of bacterial foodborne diseases and have a deeper knowledge of the type of food products associated with the major foodborne pathogens. Within the molecular techniques, DNA-based techniques have prospered for more than 40 years and have been incorporated in the first surveillance systems to monitor bacterial foodborne pathogens in the United States and other countries. However, DNA techniques vary widely and many microbiology laboratory personnel working with food and/or water face the dilemma of which method to incorporate. DNA Methods in Food Safety: Molecular Typing of Foodborne and Waterborne Bacterial Pathogens succinctly reviews more than 25 years of data on a variety of DNA typing techniques, summarizing the different mathematical models for analysis and interpretation of results, and detailing their efficacy in typing different foodborne and waterborne bacterial pathogens, such as Campylobacter, Clostridium perfringens, Listeria, Salmonella, among others. Section I describes the different DNA techniques used in the typing of bacterial foodborne pathogens, whilst Section II deals with the application of these techniques to type the most important bacterial foodborne pathogens. In Section II the emphasis is placed on the pathogen, and each chapter describes some of the most appropriate techniques for typing each bacterial pathogen. The techniques presented in this book are the most significant in the study of the molecular epidemiology of bacterial foodborne pathogens to date. It therefore provides a unique reference for students and professionals in the field of microbiology, food and water safety and epidemiology and molecular epidemiology.
Download or read book Omics Microbial Modeling and Technologies for Foodborne Pathogens written by Xianghe Yan and published by DEStech Publications, Inc. This book was released on 2012 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive information on genetic analysis and multiple omics methods, microbial modeling, and other technologies used for the analysis of foodborne pathogens. This title details the use of genomics and other omics technologies to study and classify foodborne bacteria, viruses, fungi and protozoa.
Download or read book Morbidity and Mortality Weekly Report written by and published by . This book was released on 2011 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tracing Pathogens in the Food Chain written by Stanley Brul and published by Elsevier. This book was released on 2010-11-23 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Successful methods for the detection and investigation of outbreaks of foodborne disease are essential for ensuring consumer safety. Increased understanding of the transmission of pathogens in food chains will also assist efforts to safeguard public health. Tracing pathogens in the food chain reviews key aspects of the surveillance, analysis and spread of foodborne pathogens at different stages of industrial food production and processing. Part one provides an introduction to foodborne pathogen surveillance, outbreak investigation and control. Part two concentrates on subtyping of foodborne pathogens, with chapters on phenoytypic subtyping and pulsed-field gel electrophoresis, as well as emerging methods. The vital topics of method validation and quality assurance are also covered. The focus in Part three is on particular techniques for the surveillance and study of pathogens, such as protein-based analysis, ribotyping and comparative genomics. Finally, Part four focuses on tracing pathogens in specific food chains, such as red meat and game, dairy, fish and shellfish. With its distinguished editors and international team of contributors, Tracing pathogens in the food chain is a standard reference for researchers, public health experts and food industry professionals concerned with the study and control of foodborne disease. Reviews key aspects of the surveillance, analysis and spread of foodborne pathogens Provides an overview of method validation and quality assurance Examines the tracing of pathogens in specific food chains, such as red meat, game and dairy
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2098 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book Listeria monocytogenes in ready to eat RTE foods attribution characterization and monitoring written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2022-10-14 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the 2004 risk assessment, outbreaks of illness and resultant deaths due to L. monocytogenes continue to occur across the globe. Continued effort is needed to summarize and critically evaluate the most recent information on L. monocytogenes in RTE foods. New data to improve and further inform the 2004 Risk Assessment is available for nearly every factor considered previously, including new quantitative data on L. monocytogenes contamination of foods. To facilitate this work, an FAO/WHO expert meeting was held by virtual means from 20 October to 6 November 2020 to review and discuss the available data and background documents, and to assess the need to modify and update risk assessment models/tools. This report focuses on the deliberations and conclusions of the expert meeting.
Download or read book Listeria Listeriosis and Food Safety written by Elliot T. Ryser and published by CRC Press. This book was released on 2007-03-27 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised, the new edition of this bestseller incorporates recent findings to present readers with a complete and current overview of foodborne listeriosis, including information on listeriosis in animals and humans, pathogenesis, methods of detection, and subtyping. Two new chapters deal with risk assessment, cost of outbreaks, regulatory control in various countries, and future directions for research. The text covers many high-risk foods including fermented and unfermented dairy products, meat, poultry, fish, seafood, and products of plant origin. This authoritative resource has proven in to be a critical tool for those involved with preventing and curbing outbreaks of this dangerous pathogen.
Download or read book Cornell Focus written by and published by . This book was released on 2002 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Food Protection Trends written by and published by . This book was released on 2009 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Concepts and Methods in Infectious Disease Surveillance written by Nkuchia M. M'ikanatha and published by John Wiley & Sons. This book was released on 2014-08-20 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious disease surveillance has evolved at an extraordinary pace during the past several decades, and continues to do so. It is increasingly used to inform public health practice in addition to its use as a tool for early detection of epidemics. It is therefore crucial that students of public health and epidemiology have a sound understanding of the concepts and principles that underpin modern surveillance of infectious disease. Written by leaders in the field, who have vast hands-on experience in conducting surveillance and teaching applied public health, Concepts and Methods in Infectious Disease Surveillance is comprised of four sections. The first section provides an overview, a description of systems used by public health jurisdictions in the United States and legal considerations for surveillance. The second section presents chapters on major program-area or disease-specific surveillance systems, including those that monitor bacterial infections, foodborne diseases, healthcare-associated infections, and HIV/AIDS. The following section is devoted to methods for conducting surveillance and also approaches for data analysis. A concluding section summarizes communication of surveillance findings, including the use of traditional and social media, in addition to showcasing lessons learned from the New York City Department of Health’s experience in surveillance and epidemiology training. This comprehensive new book covers major topics at an introductory to intermediate level, and will be an excellent resource for instructors. Suitable for use in graduate level courses in public health, human and veterinary medicine, and in undergraduate programs in public-health-oriented disciplines, Concepts and Methods in Infectious Disease Surveillance is also a useful primer for frontline public health practitioners, hospital epidemiologists, infection control practitioners, laboratorians in public health settings, infectious disease researchers, and medical and public health informaticians interested in a concise overview of infectious disease surveillance.
