Download or read book Development of a Parallel Computing Optimized Head Movement Correction Method in Positron Emission Tomography written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: As a modern tomographic technique, Positron-Emission-Tomography (PET) enables non-invasive imaging of metabolic processes in living organisms. It allows the visualization of malfunctions which are characteristic for neurological, cardiological, and oncological diseases. Chemical tracers labeled with radioactive positron emitting isotopes are injected into the patient and the decay of the isotopes is then observed with the detectors of the tomograph. This information is used to compute the spatial distribution of the labeled tracers. Since the spatial resolution of PET devices increases steadily, the whole sensitive process of tomograph imaging requires minimizing not only the disturbing effects, which are specific for the PET measurement method, such as random or scattered coincidences, but also external effects like body movement of the patient. Methods to correct the influences of such patient movement have been developed in previous studies at the PET center, Rossendorf. These methods are based on the spatial correction of each registered coincidence. However, the large amount of data and the complexity of the correction algorithms limited the application to selected studies. The aim of this thesis is to optimize the correction algorithms in a way that allows movement correction in routinely performed PET examinations. The object-oriented development in C++ with support of the platform independent Qt framework enables the employment of multiprocessor systems. In addition, a graphical user interface allows the use of the application by the medical assistant technicians of the PET center. Furthermore, the application provides methods to acquire and administrate movement information directly from the motion tracking system via network communication. Due to the parallelization the performance of the new implementation demonstrates a significant improvement. The parallel optimizations and the implementation of an intuitive usable graphical interface finally enables the PE.
Download or read book Development of Therapeutic Agents Handbook written by Shayne Cox Gad and published by John Wiley & Sons. This book was released on 2011-10-24 with total page 1943 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in characterizing potential drugs and their production and synthesis, Development of Therapeutic Agents Handbook gives professionals a basic tool to facilitate research and development within this challenging process. This comprehensive text brings together, in one resource, a compendium of concepts, approaches, methodologies, and limitations that need to be considered in the formulation of therapeutic agents across a range of therapeutic fields. Both a reference and a call to action for the pharmaceutical industry, Development of Therapeutic Agents Handbook examines recent innovations taking shape in the various medical disciplines involved in drug discovery, and shows why these advances need to be embraced universally among researchers to improve their solution strategies. Additional subject matter includes: Extensive coverage and in-depth look into novel treatments and therapeutics Discussion of hot topics like new drugs and nutraceuticals, the discovery and development of vaccines, cancer therapeutics, and market overviews Coverage of therapeutic drug development for specific disease areas, such as cardiology, oncology, breast cancer, and kidney diseases As research in biology, chemistry, medicine, and technology rapidly progresses, it is becoming increasingly important for medical researchers to maintain an up-to-date knowledge base of emerging trends directing promising new therapies. Development of Therapeutic Agents Handbook serves this purpose, acting as both a one-stop reference rich in valid science, and a tool to carve out new pathways in the pursuit of bringing safer and more effective drugs to the marketplace.
Download or read book Radiation Hardened CMOS Integrated Circuits for Time Based Signal Processing written by Jeffrey Prinzie and published by Springer. This book was released on 2018-04-26 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents state-of-the-art techniques for radiation hardened high-resolution Time-to-Digital converters and low noise frequency synthesizers. Throughout the book, advanced degradation mechanisms and error sources are discussed and several ways to prevent such errors are presented. An overview of the prerequisite physics of nuclear interactions is given that has been compiled in an easy to understand chapter. The book is structured in a way that different hardening techniques and solutions are supported by theory and experimental data with their various tradeoffs. Based on leading-edge research, conducted in collaboration between KU Leuven and CERN, the European Center for Nuclear Research Describes in detail advanced techniques to harden circuits against ionizing radiation Provides a practical way to learn and understand radiation effects in time-based circuits Includes an introduction to the underlying physics, circuit design, and advanced techniques accompanied with experimental data
Download or read book Poisson Point Processes written by Roy L. Streit and published by Springer Science & Business Media. This book was released on 2010-09-15 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Poisson Point Processes provides an overview of non-homogeneous and multidimensional Poisson point processes and their numerous applications. Readers will find constructive mathematical tools and applications ranging from emission and transmission computed tomography to multiple target tracking and distributed sensor detection, written from an engineering perspective. A valuable discussion of the basic properties of finite random sets is included. Maximum likelihood estimation techniques are discussed for several parametric forms of the intensity function, including Gaussian sums, together with their Cramer-Rao bounds. These methods are then used to investigate: -Several medical imaging techniques, including positron emission tomography (PET), single photon emission computed tomography (SPECT), and transmission tomography (CT scans) -Various multi-target and multi-sensor tracking applications, -Practical applications in areas like distributed sensing and detection, -Related finite point processes such as marked processes, hard core processes, cluster processes, and doubly stochastic processes, Perfect for researchers, engineers and graduate students working in electrical engineering and computer science, Poisson Point Processes will prove to be an extremely valuable volume for those seeking insight into the nature of these processes and their diverse applications.
Download or read book Electrical Electronics Abstracts written by and published by . This book was released on 1997 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book INIS Atomindex written by and published by . This book was released on 1996 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomedical Index to PHS supported Research written by and published by . This book was released on 1993 with total page 1200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomedical Index to PHS supported Research pt A Subject access A H written by and published by . This book was released on 1992 with total page 1192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1796 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computer Control Abstracts written by and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Numerical Methods for Image Registration written by Jan Modersitzki and published by Oxford University Press, USA. This book was released on 2004 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides an introduction to image registration with particular emphasis on numerical methods in medical imaging. Designed for researchers in industry and academia, it should also be a suitable study guide for graduate mathematicians, computer scientists and medical physicists.
Download or read book 99mTc Sestamibi written by Jan Bucerius and published by Springer Science & Business Media. This book was released on 2011-09-22 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: 99mTc-sestamibi is a single-photon emission computed tomography (SPECT) radiotracer that is widely used for the imaging of myocardial perfusion, as well as a variety of malignant and benign diseases. 99mTc-Sestamibi – Clinical Applications provides a detailed and informative overview of almost all the oncologic and non-oncologic applications of 99mTc-sestamibi SPECT, including several relatively rare indications. Different disease-related protocols for 99mTc-sestamibi SPECT are presented, and for each disease a comprehensive summary of the relevant pathology and epidemiology is provided. Throughout, there is a strong emphasis on the practical aspects of use of this popular tracer, including instructions for the preparation of several commercially available tracer kits. Clinical practitioners will find this book to be an invaluable guide to the application and benefits of 99mTc-sestamibi SPECT in both the inpatient and the outpatient setting.
Download or read book Cardiac SPECT Imaging written by E. Gordon DePuey and published by Lippincott Williams & Wilkins. This book was released on 2001 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac SPECT Imaging, Second Edition offers the best of all possible worlds--a critical topic, internationally recognized authors and cutting-edge coverage. It guides you through all aspects of the modality--from basic principles (acquiring and processing images, quality control)...and clinical applications (evaluating myocardial infarction and coronary artery disease)...to the very latest equipment. It even compares SPECT with other modalities (PET, CT, MRI, and echocardiography) to ensure smart, cost-effective decisions by both the cardiologist and nuclear medicine physician.Look for new chapters on attenuation correction, gated perfusion SPECT, radiopharmaceuticals, and myocardial perfusion SPECT, as well as the very latest on myocardial perfusion SPECT in conjunction with exercise and pharmacologic stress, assessment of perfusion/viability with Tc-99m agents, how SPECT compares with other advanced cardiac imaging modalities, and more!
Download or read book Endocrine Pathology with Online Resource written by Ozgur Mete and published by Cambridge University Press. This book was released on 2016-07-14 with total page 1091 pages. Available in PDF, EPUB and Kindle. Book excerpt: A much-needed comprehensive resource, Endocrine Pathology covers clinical, radiologic, biochemical, molecular, cytogenetic, immunologic and histopathologic aspects of endocrine disorders, including the full spectrum of both neoplastic and non-neoplastic lesions. The first section of the book provides an overview of the clinical presentations of endocrine diseases, while the second section reviews the wide variety of investigative techniques used in their diagnosis. The third and largest section provides a comprehensive tissue- and organ-based approach to the diagnosis of endocrine disorders, including morphologic, genetic and proteomic features with clinicopathologic correlations. All chapters are richly illustrated with numerous color images, tables and algorithms, and the book is packaged with a password, giving the user online access to all text and images. Written and edited by the world's leading experts, this comprehensive and up-to-date book is the definitive resource on endocrine pathology for all pathologists, endocrinologists and researchers.
Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1972 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book Positron Emission Tomography written by Dale L. Bailey and published by Springer Science & Business Media. This book was released on 2006-07-06 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential for students, science and medical graduates who want to understand the basic science of Positron Emission Tomography (PET), this book describes the physics, chemistry, technology and overview of the clinical uses behind the science of PET and the imaging techniques it uses. In recent years, PET has moved from high-end research imaging tool used by the highly specialized to an essential component of clinical evaluation in the clinic, especially in cancer management. Previously being the realm of scientists, this book explains PET instrumentation, radiochemistry, PET data acquisition and image formation, integration of structural and functional images, radiation dosimetry and protection, and applications in dedicated areas such as drug development, oncology, and gene expression imaging. The technologist, the science, engineering or chemistry graduate seeking further detailed information about PET, or the medical advanced trainee wishing to gain insight into the basic science of PET will find this book invaluable. This book is primarily repackaged content from the Basic Science section of the 'big' Valk book on PET. It contains new, completely revised and unchanged chapters covering the "basic sciences" section of the main book - total 18 chapters: 2 new (chapters 1, 16) 8 completely revised (chapters 4, 5, 8, 13, 14, 15, 17, 18) 3 minor corrections (chapters 2, 6, 11) 5 unchanged (chapters 3, 7, 9, 10, 12)
Download or read book Positron Emission Tomography written by Sandro Misciagna and published by BoD – Books on Demand. This book was released on 2013-12-18 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron Emission Tomography is a nuclear medicine technique first used to study the brain. Several decades ago, PET scanners design and performance have improved considerably: number of detectors has increased from 20 to 20,0000, axial field of view from 2 to 20 cm, spatial resolution has improved from 25 to 5 mm, sensitivity has increased of about 1000 fold. At the same time, clinical applications have grown dramatically. In the first section of this book the authors review some of developments in PET instrumentation, with emphasis on data acquisition, processing and image formation. In the second section authors expose examples of applications in human research. In the last section authors describe applications in assessment and prediction of oncological treatment response.
