Download or read book Development of a Motion Correction and Partial Volume Correction Algorithm for High Resolution Imaging in Positron Emission Tomography written by Shailendra Hemun Segobin and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Partial volume Correction for High resolution Positron Emission Tomography Using Cortical Surface Information written by Thomas Funck and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: " Images from high resolution brain positron emission tomography (PET) scanners (CTI/Siemens HRRT) can measure differences in neuroreceptor concentrations in the gray matter that are related to cytoarchitectonic differences. However, the loss of resolution due to the PET imaging process results in partial-volume effects (PVE) that obscure the true radiotracer distribution. Although several partial-volume correction algorithms exist, these frequently require severely limiting assumptions. We developed a new iterative deconvolution algorithm for the partial-volume correction of PET images that aims to overcome the limitations of previous methods. The proposed method does so using two innovative techniques. One is the incorporation anatomic information from a cortical gray matter surface representation, extracted from magnetic resonance imaging (MRI). The second is the use of anatomically constrained smoothing to attenuate noise in the image. This method was validated using simulated and clinical data. The results show that our method consistently recovers accurate radiotracer concentrations on simulated data sets and produces similar, though slightly overestimated, results on the real clinical data when compared to the gold-standard partial-volume correction method. " --

Download or read book Motion Correction in Thoracic Positron Emission Tomography written by Fabian Gigengack and published by Springer. This book was released on 2014-09-10 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Respiratory and cardiac motion leads to image degradation in Positron Emission Tomography (PET), which impairs quantification. In this book, the authors present approaches to motion estimation and motion correction in thoracic PET. The approaches for motion estimation are based on dual gating and mass-preserving image registration (VAMPIRE) and mass-preserving optical flow (MPOF). With mass-preservation, image intensity modulations caused by highly non-rigid cardiac motion are accounted for. Within the image registration framework different data terms, different variants of regularization and parametric and non-parametric motion models are examined. Within the optical flow framework, different data terms and further non-quadratic penalization are also discussed. The approaches for motion correction particularly focus on pipelines in dual gated PET. A quantitative evaluation of the proposed approaches is performed on software phantom data with accompanied ground-truth motion information. Further, clinical applicability is shown on patient data. The book concludes with an outlook of recent developments and potential future advances in the field of PET motion correction.

Download or read book Residual Correction Algorithms for Statistical Image Reconstruction in Positron Emission Tomography written by Lin Fu and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron emission tomography (PET) is a radionuclide imaging modality that plays important roles in visualizing, targeting, and quantifying functional processes in vivo. High-resolution and quantitative PET images are reconstructed by solving large-scale inverse problems with iterative methods that incorporate accurate physics and noise modeling of the imaging process. The computation demands of PET image reconstruction are rapidly increasing as higher-resolution detectors, larger imaging field-of-view, and dynamic or adaptive data acquisition modes are being adopted by modern PET scanners. The trend of the increase in the computation demands is even faster than Moore's law that describes the exponential growth in the number of transistors placed on an integrated circuit. In this project a residual correction mechanism is introduced to PET image reconstruction to create computationally efficient yet accurate tomographic reconstruction algorithms. By using residual correction, reconstruction methods are able to adopt a more simplified physical model for fast computation while retaining the accuracy of the final solution. Residual correction can accelerate existing image reconstruction packages. It allows iterative reconstruction with more accurate physical models which are currently impractical due to the high computation cost. Two illustrative applications of the residual correction approach are provided. One is image reconstruction with an object-dependent Monte Carlo based physics model. The other is image reconstruction using an ultra fast GPU-accelerated simplified geometric model.

Download or read book Correction Techniques in Emission Tomography written by Mohammad Dawood and published by CRC Press. This book was released on 2012-04-27 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an interdisciplinary team of medical doctors, computer scientists, physicists, engineers, and mathematicians, Correction Techniques in Emission Tomography presents various correction methods used in emission tomography to generate and enhance images. It discusses the techniques from a computer science, mathematics, and physics viewpoint.

Download or read book Quantification in Positron Emission Tomography written by Pablo Aguiar and published by LAP Lambert Academic Publishing. This book was released on 2010-10 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is focused on the development of processing, quantification and standarization methods, aimed at enhancing the quality and accuracy of Positron Emission Tomography (PET) images, both for human brain studies and for high-resolution small animal studies. Firstly, the effects of scatter, reconstruction method, anatomical variability, positron range, partial volume effect and non-colinearity on the quantification of PET studies are investigated. Several correction methods for the essential degradations are presented. Finally, the suitability of Monte Carlo techniques for simulating PET studies is also assessed.

Download or read book Event by event Motion Correction in Positron Emission Tomography written by Xiao Jin and published by . This book was released on 2013 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Development of a Parallel Computing Optimized Head Movement Correction Method in Positron Emission Tomography written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: As a modern tomographic technique, Positron-Emission-Tomography (PET) enables non-invasive imaging of metabolic processes in living organisms. It allows the visualization of malfunctions which are characteristic for neurological, cardiological, and oncological diseases. Chemical tracers labeled with radioactive positron emitting isotopes are injected into the patient and the decay of the isotopes is then observed with the detectors of the tomograph. This information is used to compute the spatial distribution of the labeled tracers. Since the spatial resolution of PET devices increases steadily, the whole sensitive process of tomograph imaging requires minimizing not only the disturbing effects, which are specific for the PET measurement method, such as random or scattered coincidences, but also external effects like body movement of the patient. Methods to correct the influences of such patient movement have been developed in previous studies at the PET center, Rossendorf. These methods are based on the spatial correction of each registered coincidence. However, the large amount of data and the complexity of the correction algorithms limited the application to selected studies. The aim of this thesis is to optimize the correction algorithms in a way that allows movement correction in routinely performed PET examinations. The object-oriented development in C++ with support of the platform independent Qt framework enables the employment of multiprocessor systems. In addition, a graphical user interface allows the use of the application by the medical assistant technicians of the PET center. Furthermore, the application provides methods to acquire and administrate movement information directly from the motion tracking system via network communication. Due to the parallelization the performance of the new implementation demonstrates a significant improvement. The parallel optimizations and the implementation of an intuitive usable graphical interface finally enables the PE.

Download or read book Quantitative Functional Brain Imaging with Positron Emission Tomography written by Richard E. Carson and published by Elsevier. This book was released on 1998-09-08 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for students and researchers who wish to take advantage of the capabilities of PET to study the normal and diseased brain. Authored by international authorities in PET Provides the latest up-to-date techniques and applications Covers all fundamental disciplines of PET in one volume A comprehensive resource for students, clinicians, and new PET researchers

Download or read book Numerical Methods for Image Registration written by Jan Modersitzki and published by Oxford University Press, USA. This book was released on 2004 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides an introduction to image registration with particular emphasis on numerical methods in medical imaging. Designed for researchers in industry and academia, it should also be a suitable study guide for graduate mathematicians, computer scientists and medical physicists.

Download or read book Development of Multispectral Scatter Correction Techniques for High resolution Positron Emission Tomography microform written by Rutao Yao and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 1997 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Motion Correction of Positron Emission Tomography Data by a Magnetic Resonance Imaging Derived Model written by Thomas Küstner and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Event Driven Motion Compensation in Positron Emission Tomography Development of a Clinically Applicable Method written by and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron emission tomography (PET) is a well-established functional imaging method used in nuclear medicine. It allows for retrieving information about biochemical and physiological processes in vivo. The currently possible spatial resolution of PET is about 5 mm for brain acquisitions and about 8 mm for whole-body acquisitions, while recent improvements in image reconstruction point to a resolution of 2 mm in the near future. Typical acquisition times range from minutes to hours due to the low signal-to-noise ratio of the measuring principle, as well as due to the monitoring of the metabolism of the patient over a certain time. Therefore, patient motion increasingly limits the possible spatial resolution of PET. In addition, patient immobilisations are only of limited benefit in this context. Thus, patient motion leads to a relevant resolution degradation and incorrect quantification of metabolic parameters. The present work describes the utilisation of a novel motion compensation method for clinical brain PET acquisitions. By using an external motion tracking system, information about the head motion of a patient is continuously acquired during a PET acquisition. Based on the motion information, a newly developed event-based motion compensation algorithm performs spatial transformations of all registered coincidence events, thus utilising the raw data of a PET system - the so-called `list-modeþ data. For routine acquisition of this raw data, methods have been developed which allow for the first time to acquire list-mode data from an ECAT Exact HR+ PET scanner within an acceptable time frame. Furthermore, methods for acquiring the patient motion in clinical routine and methods for an automatic analysis of the registered motion have been developed. For the clinical integration of the aforementioned motion compensation approach, the development of additional methods (e.g. graphical user interfaces) was also part of this work. After development, optimisation and integ.

Download or read book Basic Science of PET Imaging written by Magdy M. Khalil and published by Springer. This book was released on 2016-11-07 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.

Download or read book Partial Volume Correction of Cardiac Mouse Positron Emission Tomography Images written by Tyler Joseph Dumouchel and published by . This book was released on 2012 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book 2004 IEEE Nuclear Science Symposium Conference Record written by and published by . This book was released on 2004 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Algorithms for High resolution Positron Emission Tomography written by Kyle Morgan Champley and published by . This book was released on 2010 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: