Download or read book Development of 32P postlabelling Technique for Detection of DNA Adducts of 4 4 methylenedianiline MDA in Mice written by Dennis A. Stumpp and published by . This book was released on 1990 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Postlabelling Methods for Detection of DNA Adducts written by D. H. Phillips and published by . This book was released on 1993 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book devoted to postlabelling methods, an important new analytical methodology. Postlabelling methods have a wide range of applications: these include studies of pathways of metabolic activation of chemical carcinogens, studies of oxidative damage to DNA, monitoring occupational exposure to carcinogens, the association between DNA adducts and disease, the possible role of DNA adducts in hormonal carcinogenesis and aging, the study of complex environmental mixtures of carcinogens and monitoring the effects of such mixtures on various ecosystems. Because of the high sensitivity of the postlabelling methods, they can also be applied to humans who are exposed to low levels, and many groups have concentrated their efforts towards the evaluation of adduct formation in relation to exposure and identification of cancer causing agents.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1989 with total page 1412 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Some Chemicals Present in Industrial and Consumer Products Food and Drinking water written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.
Download or read book Toxicological Profile for Toluene written by and published by . This book was released on 2000 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book MDI and TDI Safety Health and the Environment written by D. C. Allport and published by John Wiley & Sons. This book was released on 2003-05-07 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: - MDI und TDI sind Diisocyanate, die industriell als Bausteine für Polymere verwendet werden, aber für die Gesundheit und die Umwelt nicht unbedenklich sind - erstmals werden hier Gesundheits- und Umweltrisiken von TDI und MDI gezielt in einem Band angesprochen - mit zahlreichen Photos, Spektren, Tabellen und Diagrammen - Beiträge von Experten aus Forschung, Industrie und Behörden
Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 308 Aerobic and Anaerobic Transformation in Aquatic Sediment Systems written by OECD and published by OECD Publishing. This book was released on 2002-04-24 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a laboratory test method to assess aerobic and anaerobic transformation of organic chemicals in aquatic sediment systems. The method permits the measurement of (i) the transformation rate of the test substance in a ...
Download or read book Tailoring Genes for Crop Improvement written by George Bruening and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: In August. 1982. a conference was held at the University of Califor nia. Davis. to discuss both molecular and traditional approaches to plant genetic analysis and plant breeding. Papers presented at the meeting were published in Genetic Engineering of Plants: An Agricultural Perspective. A second conference. entitled "Tailoring Genes for Crop Improvement." spon sored by the UC-Davis College of Agricultural and Environmental Sciences and the College's Biotechnology Program. was held at Davis in August. 1986. to discuss the notable advances that had been made during the intervening years in the technology for gene modification. transfer. and expression in plants. This volume contains papers that were presented at this meeting and provides readers with examples of how the new experimental strategies are being used to gain a clearer understanding of the biology of the plants we grow for food and fiber; it also discusses how molecular biology approaches are being used to introduce new genes into plants for plant breeding programs. We are grateful to the speakers for their excellent presentations for the conference and extend our sincere thanks to those who contributed manuscripts for this volume.
Download or read book Aniline Vapour written by Great Britain. HM Factory Inspectorate and published by . This book was released on 1959 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human Achondroplasia written by Benedetto Nicoletti and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the first international symposium held in Rome, Nov. 1986, study the problems of shortness of stature and attempt to find answers to the life-threatening and disabling impairments that affect achondroplasts. Contributions address genetics, ultrastructure, and cartilage histochemistry;
Download or read book Asbestiform Fibers written by Committee on Nonoccupational Health Risks of Asbestiform Fibers and published by . This book was released on 1984 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much of the more than 30 million tons of asbestos used in the United States since 1900 is still present as insulation in offices and schools, as vinyl-asbestos flooring in homes, and in other common products. This volume presents a comprehensive evaluation of the relation of these fibers to specific diseases and the extent of nonoccupational risks associated with them. It covers sources of asbestiform fibers, properties of the fibers, and carcinogenic and fibrogenic risks they pose.
Download or read book Immunotoxicity Testing written by Jamie C. DeWitt and published by Humana. This book was released on 2019-06-22 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated volume utilizes the expertise of scientists currently engaged in immunotoxicity testing to provide the reader with lab-ready procedures and the background information needed to identify effective testing approaches. Dedicated to identifying and describing exogenous agents that can modify immune function, uncovering modes and mechanisms of action for such agents, and translating data from the laboratory and from the clinic to better predict health risks as well as benefits to those who are exposed to immunomodulatory agents, immunotoxicity testing continues to be a vital field of study, and this collection highlights both the “tried and true” methods as well as alternative protocols that have been more recently developed. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immunotoxicity Testing: Methods and Protocols, Second Edition serves as a valuable contribution to the continued evolution and the application of immunotoxicity testing.
Download or read book Handbook on the Toxicology of Metals Specific metals written by Lars Friberg and published by Elsevier Science & Technology. This book was released on 1986 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.
Download or read book Toxicologic Pathology written by Pritam S. Sahota and published by CRC Press. This book was released on 2013-04-09 with total page 987 pages. Available in PDF, EPUB and Kindle. Book excerpt: As drug development shifts over time to address unmet medical needs and more targeted therapies are developed, previously unseen pharmacological or off-target effects may occur in treatment. Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, Toxicologic Pathology: Nonclinical Saf
Download or read book Poland in European Union written by Alojzy Nowak and published by SCHEDAS. This book was released on 2016-01-22 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book MECHANISMS of TOXICITY written by W. Norman Aldridge and published by . This book was released on 1971 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Monitoring of Toxic Metals written by Thomas W. Clarkson and published by Springer. This book was released on 2011-10-31 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document is the result of a conference on "Biological Monitoring of Metals" held in Rochester, June 2-6, 1986, organized jointly by the Environmental Health Sciences Center of the School of Medicine and Dentistry of the University of Rochester, NY, and the Scientific Committee on the Toxicology of Metals within the International Commission on Occupational Health (ICOH) at the Karolinska Institute and the National (Swedish) Institute of Environmental Medicine and the University of Umea, Sweden. The aim of the Conference was to define and evaluate the scientific basis for the biological monitoring of metals. The conference was co-sponsored by the World Health Organization through its International Program on Chemical Safety and received substantial encouragement and support from the Swedish Work Environmental Fund and the United States Environmental Protection Agency. This was the second conference organized jointly by the Scientific Committee on the Toxicology of Metals and The Toxicology Division of the University of Rochester. The previous joint conference was held in 1982 on the Reproductive and Developmental Toxicity of Metals. In addition, conferences have been organized by each group (see Appendices A and B). Several of these conferences are specially relevant to the topic of the current conference. These include the joint conference mentioned above and the conferences on dose-effect and dose-response relationship held in Tokyo in 1974 and on accumulation of metals held in Buenos Aires in 1972.
