Download or read book Development and Application of Integrated Silicon in plastic Microfabrication in Polymer Microfluidic Systems written by and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microfabrication for Microfluidics written by Sang-Joon John Lee and published by Artech House. This book was released on 2010 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a definitive source of knowledge about the principles, materials, and process techniques used in the fabrication of microfluidics, this practical volume is a must for your reference shelf. The book focuses on fabrication, but also covers the basic purpose, benefits, and limitations of the fabricated structures as they are applied to microfluidic sensor and actuator functions. You find guidance on rapidly assessing options and tradeoffs for the selection of a fabrication method with clear tabulated process comparisons.
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2008 with total page 886 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Highly Integrated Microfluidics Design written by Dan E. Angelescu and published by Artech House. This book was released on 2011 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent development of microfluidics has lead to the concept of lab-on-a-chip, where several functional blocks are combined into a single device that can perform complex manipulations and characterizations on the microscopic fluid sample. However, integration of multiple functionalities on a single device can be complicated. This a cutting-edge resource focuses on the crucial aspects of integration in microfluidic systems. It serves as a one-stop guide to designing microfluidic systems that are highly integrated and scalable. This practical book covers a wide range of critical topics, from fabrication techniques and simulation tools, to actuation and sensing functional blocks and their inter-compatibility. This unique reference outlines the benefits and drawbacks of different approaches to microfluidic integration and provides a number of clear examples of highly integrated microfluidic systems.
Download or read book Novel Polymer based Microfluidic Devices written by Chong Hu and published by . This book was released on 2018 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first part, we proposed an "inside-out" fabrication strategy using a copper scaffold as the sacrificial template to create freestanding 3D microvascular structures containing branched tubular networks with alginate hydrogel. The microvascular structures produced with this method are strong enough to allow handling, biocompatible for cell culture, appropriately porous to allow diffusion of small molecules, while sufficiently dense to prevent blocking of channels when embedded in various types of gels. In addition, other materials and biomolecules could be pre-loaded in our hydrogel tubular networks by mixing them with alginate solution, and the thickness of tubule wall is tunable. Compared to other potential strategies of fabricating free-standing gel channel networks, our method is parallel processing using an industrially mass-producible template, making our method rapid, low-cost and scalable. We demonstrated cell culture in a nutrition gradient based on a microfluidic diffusion device made of agar, a hydrogel traditionally hard to microfabricate, by embedding the synthesized tubules into the agar gel. In this way, the freestanding hydrogel vascular network we produced is a universal functional unit that can be integrated with other gel-based devices to build up the supporting matrix for 3D cell culture outside the hydrogel vascular structure; allowing great convenience and flexibility 3D culture. The method is readily implementable to have broad applications in biomedicine and biology, such as vascular tissue regeneration, drug discovery, and delivery system in 3D culture.
Download or read book Microfluidic Devices for Biomedical Applications written by Xiujun (James) Li and published by Elsevier. This book was released on 2013-10-31 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications.The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis.Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. - Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores in detail a wide range of medical applications - Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies - Considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering
Download or read book Microfluidics and Microfabrication written by Suman Chakraborty and published by Springer Science & Business Media. This book was released on 2009-12-15 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics and Microfabrication discusses the interconnect between microfluidics, microfabrication and the life sciences. Specifically, this includes fundamental aspects of fluid mechanics in micro-scale and nano-scale confinements and microfabrication. Material is also presented discussing micro-textured engineered surfaces, high-performance AFM probe-based, micro-grooving processes, fabrication with metals and polymers in bio-micromanipulation and microfluidic applications. Editor Suman Chakraborty brings together leading minds in both fields who also: Cover the fundamentals of microfluidics in a manner accessible to multi-disciplinary researchers, with a balance of mathematical details and physical principles Discuss the explicit interconnection between microfluiodics and microfabrication from an application perspective Detail the amalgamation of microfluidics with logic circuits and applications in micro-electronics Microfluidics and Microfabrication is an ideal book for researchers, engineers and senior-level graduate students interested in learning more about the two fields.
Download or read book Plastic Based Microfluidic Systems and Their Applications in Biology written by Palaniappan Sethu and published by . This book was released on 2002 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biochip Technology written by Jing Cheng and published by CRC Press. This book was released on 2003-09-02 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochip technology has experienced explosive growth in recent years and Biochip technology describes the basic manufacturing and fabrication processes and the current range of applications of these chips. Top scientists from the biochip industry and related areas explain the diverse applications of biochips in gene sequencing, expression monitoring, disease diagnosis, tumor examination, ligand assay and drug discovery.
Download or read book Chromatography written by E. Heftmann and published by Elsevier. This book was released on 2004-04-16 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatography has emerged as the most important and versatile analytical method. The book is not only an updated version of Heftmann's classical text, but it covers areas of future importance, such as microfluidics and computer resources. Under his experienced guidance, authorities in each field have contributed their practical experience to an integrated treatment of modern micro analysis. In Part A the theoretical basis of individual separation methods is explained and the technical aspects are illustrated. It includes the theory of gas and liquid chromatography as well as specific chromatographic techniques, such as size-exclusion, planar, ion, and affinity chromatography as well as various electrokinetic separation techniques. Microfluidics are covered for the first time and useful sources of analytical instruments are listed and evaluated.1. Each chapter written by an authority2. Thorough treatment of the theoretical basis of separation methods3. Practical guide for performing analyses
Download or read book The Integration of Active Silicon Components in Polymer Microfluidic Devices written by Michael Grad and published by . This book was released on 2013-09-06 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early microfluidic devices borrowed technology from established CMOS microfabrication, and were therefore structurally similar to silicon computer chips. In the late 1990's, George Whitesides' group pioneered a cheaper, mass producible polymer device fabrication technique called 'soft lithography' that revolutionized modern microfluidics. This dissertative work has been focused on re-introducing silicon as a common material in microfluidic devices, but as an active component instead of a structural one. These active components exploit the optical properties, electronic properties, and optoelectronic properties of silicon. The optical properties of silicon are utilized in the integration of silicon nanophotonic ring resonators as refractive index sensors embedded in microfluidic channels. The electronic properties of silicon are utilized in the fabrication of an ultra-thin Schottky diode for use as a transmission radiation particle detector for focused ion-beams. Finally, the optoelectronic properties of silicon are used as a photoconductive layer in light-induced dielectrophoretic manipulation of cells. These three projects are combined to investigate optofluidic sensing and manipulation, with potential radiobiological applications.
Download or read book A Highly integrated Polymer based Microfluidic Device for Disposable Applications written by Emil John Geiger and published by . This book was released on 2008 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Springer Handbook of Nanotechnology written by Bharat Bhushan and published by Springer. This book was released on 2017-11-05 with total page 1704 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive handbook has become the definitive reference work in the field of nanoscience and nanotechnology, and this 4th edition incorporates a number of recent new developments. It integrates nanofabrication, nanomaterials, nanodevices, nanomechanics, nanotribology, materials science, and reliability engineering knowledge in just one volume. Furthermore, it discusses various nanostructures; micro/nanofabrication; micro/nanodevices and biomicro/nanodevices, as well as scanning probe microscopy; nanotribology and nanomechanics; molecularly thick films; industrial applications and nanodevice reliability; societal, environmental, health and safety issues; and nanotechnology education. In this new edition, written by an international team of over 140 distinguished experts and put together by an experienced editor with a comprehensive understanding of the field, almost all the chapters are either new or substantially revised and expanded, with new topics of interest added. It is an essential resource for anyone working in the rapidly evolving field of key technology, including mechanical and electrical engineers, materials scientists, physicists, and chemists.
Download or read book Microfabrication Techniques for Scalable Manufacturing of Integrated Microfluidic Devices written by Jonathan Pegan and published by . This book was released on 2013 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: Micromachining techniques have enabled the rapid expansion of small-scale medical devices. However, as these techniques were originally developed for the integrated circuit industry, many of the processes and materials are ill suited for use in biological systems. Importantly, as current biomedical devices are larger then integrated circuits, scalability of manufacturing becomes a major challenge. There is a great need to discover new techniques and materials in the fabrication of biomedical microdevices that are inexpensive and can be easily scaled up for commercial production. Presented in this work are microfabrication techniques adapted for use with shape-memory polymers. These shape-memory polymers are less costly and more biocompatible then standard biomedical microdevice processes and materials. Notably, as these films are flexible, they are compatible with roll-to-roll manufacturing. These films are used to create a number of biomedical microdevices inexpensively with scalable fabrication processes to aid in the translation of biomedical microtechnology for point-of-care diagnostics.
Download or read book Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques written by James P. Landers and published by CRC Press. This book was released on 2007-12-18 with total page 1598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, this bestselling work continues to offer state-of-the-art information on the development and employment of capillary electrophoresis. With special emphasis on microseparations and microfluidics, it features new chapters describing the use of microchip electrophoresis and associated microtechniques, with a focus on the extraordinary breadth of work undertaken to expand CE methodologies in recent years. Enhanced by contributions from leading international experts, the Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques, Third Edition remains a seminal reference for the chemistry, biology, and engineering fields.
Download or read book Microfabrication and Nanomanufacturing written by Mark J. Jackson and published by CRC Press. This book was released on 2005-11-10 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology, seen as the next leap forward in the industrial revolution, requires that manufacturers develop processes that revolutionize the way small products are made. Microfabrication and Nanomanufacturing focuses on the technology of fabrication and manufacturing of engineering materials at these levels. The book provides an overview of techniques used in the semiconductor industry. It also discusses scaling and manufacturing processes operating at the nanoscale for non-semiconductor applications; the construction of nanoscale components using established lithographic techniques; bulk and surface micromachining techniques used for etching, machining, and molding procedures; and manufacturing techniques such as injection molding and hot embossing. This authoritative compilation describes non-traditional micro and nanoscale processing that uses a newly developed technique called pulsed water jet machining as well as the efficient removal of materials using optical energy. Additional chapters focus on the development of nanoscale processes for producing products other than semiconductors; the use of abrasive particles embedded in porous tools; and the deposition and application of nanocrystalline diamond. Economic factors are also presented and concern the promotion and commercialization of micro and nanoscale products and how demand will eventually drive the market.
Download or read book Development of Polymer MEMS Structures for Lab on a chips Using Uv liga and Injection Molding Techniques written by and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In this work, new polymer MEMS technology has been developed and characterized for the development of disposable microfluidic devices and lab-on-a-chips on plastic substrates. The developed technology will allow numerous applications for disposable biochips and polymer microstructures at low cost. Microfluidics has been applied for drug discovery, genomics, proteomics, clinical diagnostics, etc. So far, silicon and glass have been the two major substrate materials for the fabrication of lab-on-a-chips and microfluidic devices. The disadvantages of these substrate materials are relatively high cost compared with plastic substrates, and difficulty of mass manufacturable approaches in low-cost for the fabrication of the microfluidic devices. But for the development of low cost disposable lab-on-a-chips, novel microfabrication methods for microfluidic devices on substrates other than silicon and glass are highly desirable. Commercialization of microfluidics technology also requires low-cost and high volume fabrication methods of these microfluidic devices. Polymers are one of the good alternative substrates at low cost and their mass fabrication methods have already been established for macro polymer structures. Nickel electroplating technique has been developed for the fabrication of the master mold structure for replication of the plastic microfluidic devices. Injection molding and hot embossing techniques have been explored and optimized for high fidelity replication of the microstructures. UV LIGA technology (UV based lithography, electroplating and replication) has been adopted for manufacturing the microfluidic devices. UV lithography was done using thick photoresist (SU 8 2000 series), and the process was optimized for production of thick structures with aspect ratios of up to 10. A new polymer, cyclic olefin copolymer (COC) was extensively characterized in this work for the development of plastic microstructures using injection molding and hot embossing. Polycarbonate (PC) and polymethyl methacrylate (PMMA) were also characterized using the replication techniques. Plastic micro needles and micro capillary electrophoresis chips were fabricated and characterized using the developed polymer MEMS technologies. In this work, new polymer MEMS technologies for the development of polymer microstructures have been successfully developed and characterized, which will allow the realization of disposable BioMEMS and lab-on-a-chips on polymer or plastic substrates.
