Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Download or read book Family Medicine written by John L. Buckingham and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 783 pages. Available in PDF, EPUB and Kindle. Book excerpt: New material in a new format is contained in this third edition of Family Medicine. The comprehensive text nevertheless remains true to the goal of previous editions in offering a scientific approach to health and illness within the context of the family. Using up-to-date clinical material, the book demonstrates how the family physician may provide comprehensive health care to persons of all ages. The first part of Family Medicine discusses such topics as the conceptual basis of family as discipline and specialty, problem differentiation, family-centered health care, longitudinal care, clinical reasoning, and resource management. The second part explores both problems related to organs and systems and problems related to the person, family and community, including: pregnancy, care of infants, children, adolescents, and the elderly; behavioral and psychiatric problems; emergency and critical care; sports medicine; alcoholism and substance misuse; environmental health; and neoplastic and infectious diseases. Family Medicine, with its greatly expanded in-depth coverage of the most commonly encountered clinical core problems and procedures in family medicine, continues to be a textbook written and edited by family physicians for family physicians.

Download or read book Drug Design written by Arli Aditya Parikesit and published by BoD – Books on Demand. This book was released on 2021-06-16 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Right before the COVID-19 pandemic declared by the World Health Organization (WHO), life sciences have incited novel areas of studies that revolutionize the health sector. They are the studies of structural bioinformatics, pharmacogenomics, and metabolomics. The structural bioinformatics field is the very foundation of drug design research, as it provides insight into the molecular simulations and interactions between the biomolecules and the drug candidates. Secondly, pharmacogenomics is the starting point of any efforts in developing personalized medicine. Lastly, metabolomics provides instrumentation to elicit biomarkers for various diseases and health conditions. These studies have enabled current accelerated effort in COVID-19 research, as well as other communicable and non-communicable diseases.

Download or read book Carbohydrate based Vaccines written by René Roy and published by ACS Symposium. This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first of its kind entirely dedicated to carbohydrate vaccines written by renowned scientists with expertise in carbohydrate chemistry and immunochemistry. It covers the synthesis of carbohydrate antigens related to bacteria and parasites such as: Heamophilus influenza, Streptococcus pnemoniae, Shigella flexneri, Candida albicans, Mycobacterium tuberculosis, and Chlamydia. The first three chapters are of wide interest as they cover fundamental concerns in new vaccine developments. The first one presents the immune system and how carbohydrate antigens are processed before protective antibodies are produced. It also illustrates antigen presentation in the context of major histocompatibility complexes (MHCs). The second chapter describes regulatory issues when carbohydrate vaccines are involved while the third one discuss several techniques used in conjugation chemistry and the implication of certain chemical linkages that may induce unexpected anti-linker antibodies. This section will be particularly appealing for those involved in drug-conjugate design, pro-drug developments, and drug vectorization. The book concludes with one chapter that illustrates the principle through which peptide antigens can functionally mimic carbohydrate epitopes, thus, unraveling the potential for peptide surrogates as replacement for complex carbohydrate structures. This book is unique in that it covers all aspects related to carbohydrate vaccines including the success story with the first semi-synthetic bacterial polysaccharide vaccine against Heamophilus influenza type b responsible for pneumonia and meningitis, liable for more than 600,000 infant deaths worldwide in developing countries. The book also presents regulatory issues and will thus be vital for government agencies approving candidate vaccines. It widely covers synthetic methodologies for the attachment of carbohydrate antigens to peptides and immunogenic protein carriers. Vaccines against bacterial antigens, cancer, and parasites are also discussed by worldwide experts in this field in details. No other book contains such a wide panel of different expertise. It will also be useful to students and researchers involved with the immunology of forreings antigens and how the under appreciated carbohydrate antigens are processed by the immune system.

Download or read book Genetic Engineering News written by and published by . This book was released on 2003 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Differential Diagnosis in Cytopathology Book and Online Bundle written by Paolo Gattuso and published by Cambridge University Press. This book was released on 2014-12-04 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated edition remains the essential text for pathologists seeking to make accurate diagnoses from the vast number of differentials.

Download or read book Anticancer Drug Development written by Bruce C. Baguley and published by Elsevier. This book was released on 2001-11-17 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. - One work that can be consulted for all aspects of anticancer drug development - Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts - A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death - Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products - Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques - Hundreds of references that allow the reader to access relevant scientific and medical literature - Clear illustrations, some in color, that provide both understanding of the field and material for teaching

Download or read book Comprehensive Medicinal Chemistry II Volume 7 written by John Bodenhan Taylor and published by . This book was released on 2007 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book comprises 8 volumes, with all chapter sections available as PDF or HTML, and includes bibliographical references and index.

Download or read book Research Awards Index written by and published by . This book was released on with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1972 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Surgery of the Skin E Book written by June K. Robinson and published by Elsevier Health Sciences. This book was released on 2014-10-20 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master the latest medical and cosmetic procedures with Surgery of the Skin, the most comprehensive dermatological surgery resource available. Written from the surgeon's perspective, this medical reference book features step-by-step guidance on performing the most updated developments and cutting edge approaches across the entire spectrum of dermatologic surgery. - Improve surgical results and avoid pitfalls with expert, evidence-based guidance. - Stay on the cutting edge with in-depth step-by-step descriptions of tumescent vertical vector facelifts, blepharoplasty, composite grafts, Botox treatments, soft tissue augmentation, management of dysplastic nevi and melanoma, and more. - View immersive videos from an expanded library with more than 130 clips totaling over six hour's footage. - Explore brand-new chapters on rejuvenation of the female external genitalia; hidradenitis suppurativa; and photoaging-related mottled pigmentation. - Improve treatment outcomes for patients with skin of color and gain a truly global perspective of dermatologic surgery through an expanded contributor group of leading international experts. - Master how to perform cutting-edge techniques across the entire spectrum of dermatologic surgery, including botulinum toxins; fillers; cryosurgery; flaps; grafting; scar revisions; lasers; face-lift techniques; blepharoplasty techniques; Mohs surgery; and more. - Effectively manage a full range of complex disorders, such as vitiligo surgery, keloids, and leg ulcers, with a unique section devoted to these special procedures. - Easily visualize complex procedures and concepts with more than 1,000 illustrations, photos, and graphics. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

Download or read book Textbook of Neurointensive Care written by A Joseph Layon and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated and refined new edition is the only book to provide a comprehensive approach to the intensive care of neurologically injured patients from the emergency room and ICU through the operating room and post-surgical period. It reviews neuroanatomy, neuroradiology, and neurophysiology, examines the neurological problems most frequently seen in intensive care, and describes the various types of neurosurgery. General issues are discussed, such as cardiac care, fluids and electrolytes, nutrition, and monitoring as well as more specific conditions and complications including elevated intracranial pressure, seizures, and altered mental states.

Download or read book Understanding Pathophysiology Australia and New Zealand Edition written by Judy Craft and published by Elsevier Health Sciences. This book was released on 2022-10-15 with total page 1436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Pathophysiology Australia and New Zealand Edition

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1971 with total page 1204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Safety of Biologics Therapy written by Brian A. Baldo and published by Springer. This book was released on 2016-08-12 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters. It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of the world's 100 biggest selling drugs. Recombinant proteins dominate the growing list of the more than 200 approved biotherapeutic agents with targeted antibodies, fusion proteins and receptors; cytokines; hormones; enzymes; proteins involved in blood-clotting, homeostasis and thrombosis; vaccines; botulinum neurotoxins; and, more recently, biosimilar preparations, comprising the majority of approved biologics. Written with clinicians, other health care professionals, and researchers in mind, Safety of Biologics Therapy examines, in a single volume, the full range of issues surrounding the safety of approved biologic therapies. A good understanding of the risks and safety issues of modern biologics therapy is increasingly being demanded of all those connected with their development, handling, prescribing, administration and subsequent patient management. In addition to being of great value to clinicians in all branches of medicine, and to nurses, pharmacists and researchers, this book will prove invaluable for students taking undergraduate and graduate courses in the above disciplines and in the biomedical sciences.

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Download or read book The Microbiome and the Brain written by David Perlmutter and published by CRC Press. This book was released on 2019-12-06 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And, until recently, these mechanisms have remained somewhat elusive. The newly discovered pivotal role of the intestinal microbiome in brain health, functionality, and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain, through the contributions of some of the most forward thinking researchers and clinicians in the field, comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer’s disease, autism, multiple sclerosis, and mood disorders. In addition, mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally, novel therapeutic opportunities, derived from this exciting science are presented. Readers will learn: The highly validated relationship between alterations of gut microbes and their metabolites, and risk for Alzheimer’s disease. The important link between autism and intestinal dysbiosis. Appropriate interpretation of available laboratory assessments of the intestinal microbiome. The potential role of fecal microbial transplant in neurological diseases. The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality.