Download or read book Deterministic Versus Stochastic Modelling in Biochemistry and Systems Biology written by Paola Lecca and published by Elsevier. This book was released on 2013-04-09 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stochastic kinetic methods are currently considered to be the most realistic and elegant means of representing and simulating the dynamics of biochemical and biological networks. Deterministic versus stochastic modelling in biochemistry and systems biology introduces and critically reviews the deterministic and stochastic foundations of biochemical kinetics, covering applied stochastic process theory for application in the field of modelling and simulation of biological processes at the molecular scale. Following an overview of deterministic chemical kinetics and the stochastic approach to biochemical kinetics, the book goes onto discuss the specifics of stochastic simulation algorithms, modelling in systems biology and the structure of biochemical models. Later chapters cover reaction-diffusion systems, and provide an analysis of the Kinfer and BlenX software systems. The final chapter looks at simulation of ecodynamics and food web dynamics. Introduces mathematical concepts and formalisms of deterministic and stochastic modelling through clear and simple examples Presents recently developed discrete stochastic formalisms for modelling biological systems and processes Describes and applies stochastic simulation algorithms to implement a stochastic formulation of biochemical and biological kinetics

Download or read book Deterministic Lotsizing Models for Production Planning written by Marc Salomon and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis deals with timing and sizing decisions for production lots, and more precisely, with mathematical models to support optimal tim ing and sizing decisions. These models are called lotsizing models. They are characterized by the fact that production lots are determined based on a trade-offbetween production costs and customer service. Production costs can be categorized as basic production costs, which consist of material costs, labour costs, machine startup costs and over head costs, and inventory related costs, which include costs of capital tied up in inventory, insurances and taxes. Customer service is the capability of the firm to deliver to their clients the products in the quantity they ordered at the agreed upon time and place. The costs of realizing a certain service level are usuaIly very dif ficult to convert into money. They include costs of expediting, loss of customer goodwill, and loss of sales revenues resulting from the short age situation.

Download or read book Deterministic Threshold Models in the Theory of Epidemics written by P. Waltman and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: These notes correspond to a set of lectures given at the Univer sity of Alberta during the spring semester, 1973. The first four sec tions present a systematic development of a deterministic, threshold model for the spraad of an infection. Section 5 presents some compu tational results and attempts to tie the model with other mathematics. In each of the last three sections a separate, specialized topic is presented. The author wishes to thank Professor F. Hoppensteadt for making available preprints of two of his papers and for reading and comment ing on a preliminary version of these notes. He also wishes to thank Professor J. Mosevich for providing the graphs in Section 5. The visit at the University of Alberta was a very pleasant one and the author wishes to express his appreciation to Professors S. Ghurye and J. Macki for the invitation to visit there. Finally, thanks are due to the very competent secretarial staff at the University of Alberta for typing the original draft of the lecture notes and to Mrs. Ada Burns of the University of Iowa for her excellent typescript of the final version. TABLE OF CONTENTS 1. A Simple Epidemic Model with Permanent Removal . . . • . . . 1 2. A More General Model and the Determination of the Intensity of an Epidemic. 10 21 3. A Threshold Model. 4. A Threshold Model with Temporary Immunity. 34 5. Some Special Cases and Some Numerical Examples 48 A Two Population Threshold Model . 62 6.

Download or read book Deterministic Operations Research written by David J. Rader and published by John Wiley & Sons. This book was released on 2013-06-07 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniquely blends mathematical theory and algorithm design for understanding and modeling real-world problems Optimization modeling and algorithms are key components to problem-solving across various fields of research, from operations research and mathematics to computer science and engineering. Addressing the importance of the algorithm design process. Deterministic Operations Research focuses on the design of solution methods for both continuous and discrete linear optimization problems. The result is a clear-cut resource for understanding three cornerstones of deterministic operations research: modeling real-world problems as linear optimization problem; designing the necessary algorithms to solve these problems; and using mathematical theory to justify algorithmic development. Treating real-world examples as mathematical problems, the author begins with an introduction to operations research and optimization modeling that includes applications form sports scheduling an the airline industry. Subsequent chapters discuss algorithm design for continuous linear optimization problems, covering topics such as convexity. Farkas’ Lemma, and the study of polyhedral before culminating in a discussion of the Simplex Method. The book also addresses linear programming duality theory and its use in algorithm design as well as the Dual Simplex Method. Dantzig-Wolfe decomposition, and a primal-dual interior point algorithm. The final chapters present network optimization and integer programming problems, highlighting various specialized topics including label-correcting algorithms for the shortest path problem, preprocessing and probing in integer programming, lifting of valid inequalities, and branch and cut algorithms. Concepts and approaches are introduced by outlining examples that demonstrate and motivate theoretical concepts. The accessible presentation of advanced ideas makes core aspects easy to understand and encourages readers to understand how to think about the problem, not just what to think. Relevant historical summaries can be found throughout the book, and each chapter is designed as the continuation of the “story” of how to both model and solve optimization problems by using the specific problems-linear and integer programs-as guides. The book’s various examples are accompanied by the appropriate models and calculations, and a related Web site features these models along with MapleTM and MATLAB® content for the discussed calculations. Thoroughly class-tested to ensure a straightforward, hands-on approach, Deterministic Operations Research is an excellent book for operations research of linear optimization courses at the upper-undergraduate and graduate levels. It also serves as an insightful reference for individuals working in the fields of mathematics, engineering, computer science, and operations research who use and design algorithms to solve problem in their everyday work.

Download or read book Piecewise Deterministic Processes in Biological Models written by Ryszard Rudnicki and published by Springer. This book was released on 2017-07-20 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a concise introduction to piecewise deterministic Markov processes (PDMPs), with particular emphasis on their applications to biological models. Further, it presents examples of biological phenomena, such as gene activity and population growth, where different types of PDMPs appear: continuous time Markov chains, deterministic processes with jumps, processes with switching dynamics, and point processes. Subsequent chapters present the necessary tools from the theory of stochastic processes and semigroups of linear operators, as well as theoretical results concerning the long-time behaviour of stochastic semigroups induced by PDMPs and their applications to biological models. As such, the book offers a valuable resource for mathematicians and biologists alike. The first group will find new biological models that lead to interesting and often new mathematical questions, while the second can observe how to include seemingly disparate biological proc esses into a unified mathematical theory, and to arrive at revealing biological conclusions. The target audience primarily comprises of researchers in these two fields, but the book will also benefit graduate students.

Download or read book Mathematical Models of Chemical Reactions written by Péter Érdi and published by Manchester University Press. This book was released on 1989 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Operations Research written by Katta G. Murty and published by Pearson College Division. This book was released on 1995 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic text on deterministic optimization methods. Techniques of modeling real world decision making problems, modeling examples that illustrate the use of modeling techniques, and a variety of problem classes are presented. Various types of algorithms with explanations of how each algorithm works and what conclusion can be drawn from its output, and a review of Matrix Algebra and Geometry and a chapter on Heuristic Methods.

Download or read book Qualitative Analysis of Human Movement written by Duane V. Knudson and published by Human Kinetics. This book was released on 2002 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forlagets beskrivelse: An interdisciplinary approach to the qualitative analysis of human movement. The authors explain how to blend experience and sport science to improve movement. The accompanying CD-ROM is designed to help the user improve their observational and analytical skills.

Download or read book Deterministic and Stochastic Optimal Control written by Wendell H. Fleming and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book may be regarded as consisting of two parts. In Chapters I-IV we pre sent what we regard as essential topics in an introduction to deterministic optimal control theory. This material has been used by the authors for one semester graduate-level courses at Brown University and the University of Kentucky. The simplest problem in calculus of variations is taken as the point of departure, in Chapter I. Chapters II, III, and IV deal with necessary conditions for an opti mum, existence and regularity theorems for optimal controls, and the method of dynamic programming. The beginning reader may find it useful first to learn the main results, corollaries, and examples. These tend to be found in the earlier parts of each chapter. We have deliberately postponed some difficult technical proofs to later parts of these chapters. In the second part of the book we give an introduction to stochastic optimal control for Markov diffusion processes. Our treatment follows the dynamic pro gramming method, and depends on the intimate relationship between second order partial differential equations of parabolic type and stochastic differential equations. This relationship is reviewed in Chapter V, which may be read inde pendently of Chapters I-IV. Chapter VI is based to a considerable extent on the authors' work in stochastic control since 1961. It also includes two other topics important for applications, namely, the solution to the stochastic linear regulator and the separation principle.

Download or read book Models in Ecology written by John Maynard-Smith and published by Cambridge University Press. This book was released on 1974-01-17 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is aimed at anyone with a serious interest in ecology. Ecological models of two kinds are dealt with: mathematical models of a strategic kind aimed at an understanding of the general properties of ecosystems and laboratory models designed with the same aim in view. The mathematical and experimental models illuminate one another. A strength of the account is that although there is a good deal of mathematics, Professor Maynard Smith has concentrated on making clear the assumptions behind the mathematics and the conclusions to be drawn. Proofs and derivations have been omitted as far as possible. The book is therefore comprehensible to anyone with a minimal familiarity with mathematical notation. This book was written in the twin convictions that ecology will not come of age until it has a sound theoretical basis and there is a long way to go before that state of affairs is reached.

Download or read book Dynamic Programming and Optimal Control written by Dimitri P. Bertsekas and published by . This book was released on 2005 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The leading and most up-to-date textbook on the far-ranging algorithmic methododogy of Dynamic Programming, which can be used for optimal control, Markovian decision problems, planning and sequential decision making under uncertainty, and discrete/combinatorial optimization. The treatment focuses on basic unifying themes, and conceptual foundations. It illustrates the versatility, power, and generality of the method with many examples and applications from engineering, operations research, and other fields. It also addresses extensively the practical application of the methodology, possibly through the use of approximations, and provides an extensive treatment of the far-reaching methodology of Neuro-Dynamic Programming/Reinforcement Learning. The first volume is oriented towards modeling, conceptualization, and finite-horizon problems, but also includes a substantive introduction to infinite horizon problems that is suitable for classroom use. The second volume is oriented towards mathematical analysis and computation, treats infinite horizon problems extensively, and provides an up-to-date account of approximate large-scale dynamic programming and reinforcement learning. The text contains many illustrations, worked-out examples, and exercises."--Publisher's website.

Download or read book Mathematical Modeling of Random and Deterministic Phenomena written by Solym Mawaki Manou-Abi and published by John Wiley & Sons. This book was released on 2020-04-28 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights mathematical research interests that appear in real life, such as the study and modeling of random and deterministic phenomena. As such, it provides current research in mathematics, with applications in biological and environmental sciences, ecology, epidemiology and social perspectives. The chapters can be read independently of each other, with dedicated references specific to each chapter. The book is organized in two main parts. The first is devoted to some advanced mathematical problems regarding epidemic models; predictions of biomass; space-time modeling of extreme rainfall; modeling with the piecewise deterministic Markov process; optimal control problems; evolution equations in a periodic environment; and the analysis of the heat equation. The second is devoted to a modelization with interdisciplinarity in ecological, socio-economic, epistemological, demographic and social problems. Mathematical Modeling of Random and Deterministic Phenomena is aimed at expert readers, young researchers, plus graduate and advanced undergraduate students who are interested in probability, statistics, modeling and mathematical analysis.

Download or read book Handbook of EOQ Inventory Problems written by Tsan-Ming Choi and published by Springer Science & Business Media. This book was released on 2013-08-17 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Economic Order Quantity (EOQ) inventory model first appeared in 1913, and in its centennial, it is still one of the most important inventory models. Despite the abundance of both classical and new research results, there was (until now) no comprehensive reference source that provides the state-of-the-art findings on both theoretical and applied research on the EOQ and its related models. This edited handbook puts together all these interesting works and the respective insights into an edited volume. The handbook contains papers which explore both the deterministic and the stochastic EOQ-model based problems and applications. It is organized into three parts: Part I presents three papers that provide an introduction and review of various EOQ related models. Part II includes four technical analyses on single-echelon EOQ-model based inventory problems. Part III consists of five papers on applications of the EOQ model for multi-echelon supply chain inventory analysis.

Download or read book Methods and Models written by Rebecca B. Morton and published by Cambridge University Press. This book was released on 1999-08-28 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: At present much of political science consists of a large body of formal mathematical work that remains largely unexplored empirically and an expanding use of sophisticated statistical techniques. While there are examples of noteworthy efforts to bridge the gap between these, there is still a need for much more cooperative work between formal theorists and empirical researchers in the discipline. This book explores how empirical analysis has, can, and should be used to evaluate formal models in political science. The book is intended to be a guide for active and future political scientists who are confronting the issues of empirical analysis with formal models in their work and as a basis for a needed dialogue between empirical and formal theoretical researchers in political science. These developments, if combined, are potentially a basis for a new revolution in political science.

Download or read book Modeling with Stochastic Programming written by Alan J. King and published by Springer Nature. This book was released on with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mathematical Approaches for Emerging and Reemerging Infectious Diseases An Introduction written by Carlos Castillo-Chavez and published by Springer Science & Business Media. This book was released on 2002-05-02 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book grew out of the discussions and presentations that began during the Workshop on Emerging and Reemerging Diseases (May 17-21, 1999) sponsored by the Institute for Mathematics and its Application (IMA) at the University of Minnesota with the support of NIH and NSF. The workshop started with a two-day tutorial session directed at ecologists, epidemiologists, immunologists, mathematicians, and scientists interested in the study of disease dynamics. The core of this first volume, Volume 125, covers tutorial and research contributions on the use of dynamical systems (deterministic discrete, delay, PDEs, and ODEs models) and stochastic models in disease dynamics. The volume includes the study of cancer, HIV, pertussis, and tuberculosis. Beginning graduate students in applied mathematics, scientists in the natural, social, or health sciences or mathematicians who want to enter the fields of mathematical and theoretical epidemiology will find this book useful.

Download or read book Mathematical Approaches for Emerging and Reemerging Infectious Diseases Models Methods and Theory written by Carlos Castillo-Chavez and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This IMA Volume in Mathematics and its Applications MATHEMATICAL APPROACHES FOR EMERGING AND REEMERGING INFECTIOUS DISEASES: MODELS, AND THEORY METHODS is based on the proceedings of a successful one week workshop. The pro ceedings of the two-day tutorial which preceded the workshop "Introduction to Epidemiology and Immunology" appears as IMA Volume 125: Math ematical Approaches for Emerging and Reemerging Infectious Diseases: An Introduction. The tutorial and the workshop are integral parts of the September 1998 to June 1999 IMA program on "MATHEMATICS IN BI OLOGY. " I would like to thank Carlos Castillo-Chavez (Director of the Math ematical and Theoretical Biology Institute and a member of the Depart ments of Biometrics, Statistics and Theoretical and Applied Mechanics, Cornell University), Sally M. Blower (Biomathematics, UCLA School of Medicine), Pauline van den Driessche (Mathematics and Statistics, Uni versity of Victoria), and Denise Kirschner (Microbiology and Immunology, University of Michigan Medical School) for their superb roles as organizers of the meetings and editors of the proceedings. Carlos Castillo-Chavez, es pecially, made a major contribution by spearheading the editing process. I am also grateful to Kenneth L. Cooke (Mathematics, Pomona College), for being one of the workshop organizers and to Abdul-Aziz Yakubu (Mathe matics, Howard University) for serving as co-editor of the proceedings. I thank Simon A. Levin (Ecology and Evolutionary Biology, Princeton Uni versity) for providing an introduction.