Download or read book Malaria written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

Download or read book Proceedings of Seventh International Conference on Bio Inspired Computing Theories and Applications BIC TA 2012 written by Jagdish C. Bansal and published by Springer Science & Business Media. This book was released on 2012-12-04 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is a collection of high quality peer reviewed research papers presented in Seventh International Conference on Bio-Inspired Computing (BIC-TA 2012) held at ABV-IIITM Gwalior, India. These research papers provide the latest developments in the broad area of "Computational Intelligence". The book discusses wide variety of industrial, engineering and scientific applications of nature/bio-inspired computing and presents invited papers from the inventors/originators of novel computational techniques.

Download or read book World Malaria Report 2019 written by World Health Organization and published by . This book was released on 2019-08-28 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Malaria Report 2019 provides a comprehensive update on global and regional malaria data and trends. The report tracks investments in malaria programs and research as well as progress across all intervention areas: prevention, diagnosis, treatment, elimination, and surveillance. It also includes dedicated chapters on the consequences of malaria on maternal infant and child health the "High Burden to High Impact" approach as well as biological threats to the fight against malaria. The 2019 report is based on information received from more than 80 countries and areas with ongoing malaria transmission. This information is supplemented by data from national household surveys and databases held by other organizations.

Download or read book Basic Malaria Microscopy Tutor s guide written by World Health Organization and published by World Health Organization. This book was released on 2010 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes questionnaire for evaluation of training in volume 2.

Download or read book Encyclopedia of Malaria written by and published by Springer. This book was released on 2018-07-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Malaria represents a vast databank of information about the study of malaria. It provides an overview of the historical, rapid and significant developments that have occurred in malaria research, including the 2002 genome sequencing of Plasmodium falciparum and its mosquito vector, Anopheles gambiae. This work provides a concise source of up-to-date research findings in the form of definitions and essays and present comprehensive coverage of topics from history to findings to diagnosis and treatment, written by recognized malaria researchers with practical experience. It appeals to a diverse audience, including malaria researchers, teachers, investigators and public health professionals.

Download or read book Detection of Plasmodium Falciparum written by Renate Zelger and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is one of the most deadly infectious diseases, responsible for 438 000 deaths and 214 million infections per year, mostly in developing countries. Ultra-sensitive detection of the asexual and sexual forms of Plasmodium spp., the causative agent of malaria, is crucial to reduce the staggering numbers of malaria infections with the ultimate goal of eradication, and it is important for research. Unfortunately all current detection methods and biomarkers for malaria have limitations. The performance of antigen-detection assays depends strongly on the biomarker detected, the antibodies used to target the biomarker and the detection method itself. The goal of this project was to improve the detection of Plasmodium falciparum by addressing these three main factors. First, novel biomarkers were identified in a bioinformatics approach, then experimentally characterized and evaluated for their suitability to use in diagnostic tests. KAHRP and PFD1170c were recognized as potential markers for asexual stage parasites. A particular focus was on biomarkers specific for gametocytes, as gametocytes are the only stage able to infect mosquitos, therefore crucial for the spread of the disease and prime targets for transmission blocking strategies. Potential gametocytes specific biomarkers were selected through a transcriptome study of field samples. The candidates were then GFP-tagged for characterization at the protein level. PFC0685w was identified as gametocyte specific biomarker. The detection limit of antigen-detection assays depends on the availability of high affinity antibodies targeting the biomarker. A limiting factor for the generation of high affinity antibodies is the difficulty of expressing Plasmodium antigens required for antibody generation. Dictyostelium discoideum was assessed as an alternative host for the recombinant antigen expression. KAHRP was successfully expressed in Dictyostelium discoideum using an inducible system. An immuno-qPCR, the so-called TT-lock immuno-qPCR was adapted for the quantitative detection of malaria parasites. In general, immuno-qPCR uses a DNA-conjugated antibody to detect a specific antigen by PCR amplification. Its advantage is an unprecedented sensitivity. However, one major challenge in immuno-qPCR is the synthesis of protein-DNA conjugates. The TT-lock immuno-qPCR uses the strong interaction between the DNA-binding protein Tus and a specific DNA sequence for the protein-DNA conjugation. The TT-lock immuno-qPCR has been optimized to detect PfLDH, a widely used biomarker in commercial available rapid diagnostic tests. The assay performed well in detecting recombinant PfLDH, but for the detection of parasite material it did not perform better than already existing methods. The findings of this study highlight the difficulties of improving malaria diagnosis using antigens. To find the right antibodies for a detection method is a challenging task, as each antibody needs to be evaluated experimentally and the generation of new antibodies does not guarantee a higher quality. In hand go the challenges to express recombinant antigen needed for antibody generation. Furthermore, the detection method optimized in this study needs further fine-tuning to push the limit of detection, even after extensive attempts of optimization.

Download or read book Rodent Malaria written by R. Killick-Kendrick and published by Elsevier. This book was released on 2012-12-02 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rodent Malaria reviews significant findings concerning malaria parasites of rodents, including their taxonomy, zoogeography, and evolution, along with life cycles and morphology; genetics and biochemistry; and concomitant infections. This volume is organized into eight chapters and begins by sketching out the history of the discovery of rodent as well as aspects of parasitology, immunology, and chemotherapy. These concepts are investigated two decades following Ignace Vincke's major discovery and Meir Yoeli's successful establishment of the method of cyclical transmission of the parasite. The following chapters focus on the taxonomy and systematics of the subgenus Vinckeia, with reference to the concepts of species and subspecies of animals and the degree to which they apply to malaria parasites, in particular to those of rodents. The discussion then shifts to how the rodent malaria parasites provide a unique insight into the subcellular organization of Plasmodium species, the use of rodent malaria as an experimental model to study immunological responses, and infectious agents that interact with malaria parasites. The book concludes with a chapter on malaria chemotherapy, with emphasis on the value of rodent malaria in antimalarial drug screening and the use of antimalarial drugs as biological probes. This book will be of interest to protozoologists and physicians as well as those from other disciplines including biochemistry, immunology, pharmacology, cell biology, and genetics.

Download or read book Guidelines for the Treatment of Malaria written by World Health Organization and published by World Health Organization. This book was released on 2010 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV positive, travellers from non-malaria endemic regions) and in complex emergency situations and severe malaria."--Publisher's description.

Download or read book Malaria Microscopy Quality Assurance Manual written by World Health Organization and published by . This book was released on 2016 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Essential Malariology written by Leonard Jan Bruce-Chwatt and published by John Wiley & Sons. This book was released on 1985 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Diagnostic Medical Parasitology written by Lynne Shore Garcia and published by John Wiley & Sons. This book was released on 2020-08-06 with total page 1388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Medical Parasitology covers all aspects of human medical parasitology and provides detailed, comprehensive, relevant diagnostic methods in one volume. The new edition incorporates newly recognized parasites, discusses new and improved diagnostic methods, and covers relevant regulatory requirements and has expanded sections detailing artifact material and histological diagnosis, supplemented with color images throughout the text.

Download or read book Guidelines for the Treatment of Malaria Third Edition written by World Health Organization and published by World Health Organization. This book was released on 2015-08-13 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all countries in which P. falciparum malaria is endemic have progressively updated their treatment policy from use of ineffective monotherapy to the currently recommended artemisinin-based combination therapies (ACT). This has contributed substantially to current reductions in global morbidity and mortality from malaria. Unfortunately resistance to artemisinins has arisen recently in P. falciparum in South-East Asia which threatens these gains. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on a firmer evidence base for most antimalarial drugs and in addition include recommendation on the use of drugs to prevent malaria in groups at high risk. The Guidelines provide a framework for designing specific detailed national treatment protocols taking into account local patterns of resistance to antimalarial drugs and health service capacity. It provides recommendations on treatment of uncomplicated and severe malaria in all age groups all endemic areas in special populations and several complex situations. In addition on the use of antimalarial drugs as preventive therapy in healthy people living in malaria-endemic areas who are high risk in order to reduce morbidity and mortality from malaria. The Guidelines are designed primarily for policy-makers in ministries of health who formulate country-specific treatment guidelines. Other groups that may find them useful include health professionals and public health and policy specialists that are partners in health or malaria control and the pharmaceutical industry. The treatment recommendations in the main document are brief; for those who wish to study the evidence base in more detail a series of annexes is provided with references to the appropriate sections of the main document.

Download or read book Deep Learning Applications in Medical Imaging written by Saxena, Sanjay and published by IGI Global. This book was released on 2020-10-16 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Before the modern age of medicine, the chance of surviving a terminal disease such as cancer was minimal at best. After embracing the age of computer-aided medical analysis technologies, however, detecting and preventing individuals from contracting a variety of life-threatening diseases has led to a greater survival percentage and increased the development of algorithmic technologies in healthcare. Deep Learning Applications in Medical Imaging is a pivotal reference source that provides vital research on the application of generating pictorial depictions of the interior of a body for medical intervention and clinical analysis. While highlighting topics such as artificial neural networks, disease prediction, and healthcare analysis, this publication explores image acquisition and pattern recognition as well as the methods of treatment and care. This book is ideally designed for diagnosticians, medical imaging specialists, healthcare professionals, physicians, medical researchers, academicians, and students.

Download or read book Blood Cells written by Barbara J. Bain and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood Cells has been written with both the practisinghaematologist and the trainee in mind. It aims to provide a guidefor use in the diagnostic haematology laboratory, covering methodsof collection of blood specimens, blood film preparation andstaining, the principles of manual and automated blood counts andthe assessment of the morphological features of blood cells. Thepractising haematologist should find this book sufficientlycomprehensive to be a reference source while, at the same time, thetrainee haematologist and biomedical scientist should find it astraightforward and practical bench manual. Enables both the haematologist and laboratory scientist toidentify blood cell features, from the most common to the moreobscure Provides essential information on methods of collection, bloodfilm preparation and staining, together with the principles ofmanual and automated blood counts Completely revised and updated, incorporating much newlypublished information: now includes advice on further tests when aspecific diagnosis is suspected Four hundred high quality photographs to aid with blood cellidentification Highlights the purpose and clinical relevance of haematologylaboratory tests throughout

Download or read book World Malaria Report 2015 written by World Health Organization and published by World Health Organization. This book was released on 2016-01-30 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Malaria Report 2015assesses global malaria disease trends and changes in the coverage and financing of malaria control programs between 2000 and 2015. It also summarizes progress towards international targets, and provides regional and country profiles that summarize trends in each WHO region and each country with malaria. The report is produced with the help of WHO regional and country offices, ministries of health in endemic countries, and a broad range of other partners. The data presented are assembled from the 96 countries and territories with ongoing malaria transmission, and a further five countries that have recently eliminated malaria. Most data are those reported for 2014 and 2015, although in some cases projections have been made into 2015, to assess progress towards targets for 2015.

Download or read book Molecular Methods for the Detection of Plasmodium Falciparum Infections Under Field Conditions written by Ronald W. Finnegan and published by . This book was released on 1997 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book CDC Yellow Book 2018 Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.