Download or read book Detection of Biological Species by Surface Enhanced Raman Scattering written by Atanu Sengupta and published by . This book was released on 2006 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Surface Enhanced Raman Spectroscopy written by Marek Prochazka and published by Springer. This book was released on 2015-12-12 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.

Download or read book Applications of Raman Spectroscopy to Biology written by M. Ghomi and published by IOS Press. This book was released on 2012-02-23 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Raman spectroscopy has been known and used as a technique for 80 years, originally for the study of inorganic substances. Recent advances in underlying technology, such as lasers, detectors, filters and components, have transformed the technique into a very effective modern tool for studying complex biological problems. Professor Mahmoud Ghomi (of the University of Paris XIII) has edited this book on the applications of Raman spectroscopy to biology, covering in a readily accessible way the area from basic studies to the diagnosis of disease. The early chapters provide background information on basic principles underlying the main Raman methods covered in the book, with information on Surface-Enhanced Raman Scattering (SERS) and Surface-Enhanced Fluorescence (SEF), as well as giving accounts of applications to biomolecular and cellular investigations. Among the topics covered are studies of drugs and their complexes with biomolecules on nanoparticles, application of SERS to blood analysis, studies of single cells and of applications to human cancer diagnostics.This will be a useful book for experimental scientists in academic, governmental, industrial and clinical environments and for those entering the field of biomolecular spectroscopy.

Download or read book Nanophotonics in Biomedical Engineering written by Xiangwei Zhao and published by Springer Nature. This book was released on 2020-10-23 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the latest advances in nanophotonics for biomedical applications, including biomolecular sensing and imaging, additive fabrications, and biophotonics. The engineering of nanophotonics will have significant impacts on the life sciences and medicine alike. Given its scope, the book offers a valuable asset for researchers, scientists, engineers, and graduate students in the fields of biomedical engineering, electrical engineering, materials sciences, optics, biology, and medicine.

Download or read book Near Infrared Surface Enhanced Raman Scattering SERS Mediated Identification of Single Optically Trapped Bacterial Spores written by and published by . This book was released on 2003 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: A novel methodology has been developed for the investigation of bacterial spores. Specifically, this method has been used to probe the spore coat composition of several Bacillus species. This technique may be useful in many applications; most notably, development of novel detection schemes toward potentially harmful biological agents. This method would also be useful as an ancillary environmental monitoring system where sterility is of importance (i.e., food preparation areas as well as invasive and minimally invasive medical applications). This unique detection scheme is based on the near-infrared (NIR) Surface-Enhanced-Raman-Scattering (SERS) from single, optically trapped, bacterial spores. The SERS spectra of several bacterial spores in aqueous media have been measured using SERS substrates based on 60-nm diameter gold colloids bound to 3-Aminopropyftriethoxysilane derivatized glass. The light from a 785-nm laser diode was used to capture/manipulate as well as simultaneously excite the SERS of an individual bacterial spore. The collected SERS spectra were examined for uniqueness and the applicability of this technique for the species identification of bacterial spores.

Download or read book Surface Enhanced Vibrational Spectroscopy written by Ricardo Aroca and published by John Wiley & Sons. This book was released on 2006-05-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Enhanced Vibrational Spectroscopy (SEVS) has reached maturity as an analytical technique, but until now there has been no single work that describes the theory and experiments of SEVS. This book combines the two important techniques of surface-enhanced Raman scattering (SERS) and surface-enhanced infrared (SEIR) into one text that serves as the definitive resource on SEVS. Discusses both the theory and the applications of SEVS and provides an up-to-date study of the state of the art Offers interpretations of SEVS spectra for practicing analysts Discusses interpretation of SEVS spectra, which can often be very different to the non-enhanced spectrum - aids the practicing analyst

Download or read book Principles and Clinical Diagnostic Applications of Surface Enhanced Raman Spectroscopy written by Yuling Wang and published by Elsevier. This book was released on 2021-09-17 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy summarizes the principles of surface-enhanced Raman scattering/spectroscopy (SERS) and plasmonic nanomaterials for SERS, with a focus on SERS applications in clinical diagnostics. This book covers the key concepts from the fundamentals, materials, experimental aspects, and applications of SERS in clinical diagnostics with discussions on label-free/direct SERS assay, design and synthesis of SERS nanotags, SERS nanotags for point-of-care diagnostics, microfluidic SERS assay, and in vitro and in vivo sensing and imaging. Written by experts from around the world, this comprehensive volume showcases the recent progress of SERS applications in clinical diagnostics and helps readers understand when and how to use SERS in a clinical setting. Introduces the basics of SERS and suitable nanomaterials for SERS application Gives an overview of the cutting-edge research on SERS applications for clinical diagnosis, including the latest advances in our understanding of underlying principles to enable material design and clinical applications Gradually builds from the fundamental concepts to the applications of SERS for clinical diagnostics

Download or read book Detection of Molecular and Biomolecular Species by Surface Enhanced Raman Scattering Nanoengineered Substrates for SERS Detection written by and published by . This book was released on 2004 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our research has confirmed that the significant Raman enhancement from a nanoshell based substrate is generated by the electromagnetic enhancement of individual nanoshells, not aggregates (dimers, trimers, etc.). Unlike metal colloids and roughened surfaces, the significant Raman enhancements achieved are consistent across the substrate and are not related to "hot spots" associated with aggregate geometries. This will allow the reproducible manufacture of a substrate with superior enhancement for use in future target specific SERS applications. The Raman enhancement achieved this individual nanoshell" substrate equals or exceeds 10 exp 10, evaluated using direct comparison between the unenhanced and enhanced signal from the same molecule. It is important to note that when these enhancements are compared to those of Kneipp et a., who reported values of 10 exp 10, the nanoshell-based enhancement appears to be approximately 10 exp 15 using their analytical method. The enhancement factors demonstrated are consistent with reported enhancements factors necessary for single molecule detection. Nanoshell-based SERS substrates have been reproducibly manufactured and tested for stability under various conditions. The method of manufacturing will allow use with both dry and aqueous samples.

Download or read book Practical Raman Spectroscopy written by Peter Vandenabeele and published by John Wiley & Sons. This book was released on 2013-07-03 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text offers an open-learning approach to Raman spectroscopy providing detail on instrumentation, applications and discussions questions throughout the book. It provides a valuable guide to assist with teaching Raman spectroscopy which is gaining attention in (analytical) chemistry, and as a consequence, teaching programs have followed. Today, education in Raman spectroscopy is often limited to theoretical aspects (e.g. selection rules), but practical aspects are usually disregarded. With these course notes, the author hopes to fill this gap and include information about Raman instrumentation and how it is interpreted. Provides a user-friendly text that tackles the theoretical background, and offers everyday tips for common practice Raman instrumentation and practical aspects, which are sometimes overlooked, are covered Appropriate for students, and includes summaries, text boxes, illustrating the ideas with examples from research literature or providing background information or links with other courses Written with an open-learning approach, this book will be ideal for use as a self-study guide or as the basis of a taught course with discussion and self-assessment questions throughout the text Includes a comprehensive bibliography to guide the reader to more specialized texts and sources.

Download or read book Trace Analysis of Biological Compounds by Surface Enhanced Raman Scattering SERS Spectroscopy written by Naresh Kumar Boddu and published by . This book was released on 2008 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface enhanced Raman scattering (SERS) spectroscopy is a sensitive analytical technique, which extends its applications to the detection of substances at low concentration levels. SERS spectroscopy measurements were performed on adenine and rhodamine 6G on silver and gold colloids to evaluate the linearity at low analyte concentrations and at different time intervals. The maximum intensity for adenine was observed at Raman shifts of 728 cm-1 and 1318 cm-1 and the maximum intensity for R6G was observed at Raman shifts of 1352 cm-1 and 1519 cm-1. These SERS measurements were compared with solution absorbance measurements at 650 nm and 900 nm. Raman enhancement factors have also been evaluated for each compound. The results of these studies demonstrate that SERS techniques provide high sensitivity and have the potential to detect a range of compounds in biological samples.

Download or read book Frontiers of Surface Enhanced Raman Scattering written by Yukihiro Ozaki and published by John Wiley & Sons. This book was released on 2014-02-19 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive presentation of Surface-Enhanced Raman Scattering (SERS) theory, substrate fabrication, applications of SERS to biosystems, chemical analysis, sensing and fundamental innovation through experimentation. Written by internationally recognized editors and contributors. Relevant to all those within the scientific community dealing with Raman Spectroscopy, i.e. physicists, chemists, biologists, material scientists, physicians and biomedical scientists. SERS applications are widely expanding and the technology is now used in the field of nanotechnologies, applications to biosystems, nonosensors, nanoimaging and nanoscience.

Download or read book Surface Enhanced Raman Scattering New Theoretical Approaches Materials and Strategies written by Ivano Alessandri and published by Frontiers Media SA. This book was released on 2020-03-25 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Ag Nano dendritic Three dimensional 3D Surface enhanced Raman Scattering SERS Substrate for In situ Liquid Media Detection written by Milind Mansing Pawar and published by . This book was released on 2019 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuous monitoring of certain environmental pollutants, biological species, chemical species, and explosives are of utmost importance in recent times. Surface-enhanced Raman scattering (SERS) provides most promising option as it is a highly sensitive technique which allows for ultrasensitive detection of molecules and provides excellent structural information. To obtain rich results through Surface-enhanced Raman scattering, proper design of enhancing substrate plays vital role. Contemporary SERS substrates don't provide ease to detect liquid analytes for in-situ spectroscopy. Liquid media detection through SERS relies on highly statistical binding of analytes to SERS-sensitive hot spots. Moreover, it becomes extremely difficult to detect flowing liquid media in-situ with two dimensional substrates as very small volume of Liquid contact with substrates. Single crystal Ag dendrite structures possess high surface area along with narrow gaps and sharp edges. Compared with other nanostructures, the hierarchical nanostructures-dendritic Ag, consisting of multi-level branches can significantly promote the SERS enhancement and serve as effective SERS substrates with high sensitivity and reproducibility. Such complex nanostructures may provide a large amount of "hot spots" at the end of branches or the junctions of adjacent Ag branches. In addition, the large surface area of Ag dendrites can enhance the interaction between analytes and sensing substrates. Ag dendrites can easily be produced, by use of one of the simplest galvanic reactions, the reaction of AgNO3 with Cu. We have developed novel yet simple Surface-enhanced Raman scattering- active substrate having three-dimensional array of Ag-dendrites grown within square geometry capillary tube of borosilicate glass via such galvanic replacement reaction with inserted copper wire. Systematic study of growth mechanism of Ag-dendrites was carried out and complex nature of seemingly "simple" galvanic replacement reaction has been proposed. The resultant Ag dendrites were characterized by scanning electron microscopy, transmission electron microscopy, energy dispersive spectroscopy and X-ray diffraction. Atime-dependent investigation on the growth mechanism of the Ag dendrites revealed that they develop through a particle-mediated growth process. The effect of the reactant concentrations on the morphology of the synthesized Ag dendrites was also studied. This study on Ag dendrite growth mechanisms are not only scientifically intriguing, but also technologically important. Novel Ag dendrite three-dimensional SERS substrate exhibits excellent sensitivity and a very good reproducibility. We have detected rhodamine 6G(R6G) with lowest concentration of 10-11 M in aqueous solution. These Ag dendrite nanostructured three-dimensional SERS substrates are proved as excellent in-situ liquid media Raman detection substrates due to availability of extensive hot spots. It has significant potential to be used as SERS substrates for fast and accurate detection of trace amount of organic contaminants in flowing liquid media.

Download or read book Surface enhanced Raman Scattering to Detect and Identify Trace Amounts of Chemical Biological and Explosive Warefare Agents written by and published by . This book was released on 2008 with total page 31 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fabrication of Surface Enhanced Raman Scattering SERS Substrates Made from Nanoparticle Printing Inks for Detection of Biological Molecules written by Manuel Alejandro Figueroa and published by . This book was released on 2013 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface enhanced Raman scattering ΔΟΠ� ϝαπ ϛδλδοαϟδγ ϛοδαϟ ζλϟδοδπϟ απ α προεαϐδ αλαιυϟζϐαι ϟδϐϝλζξρδ βδϐαρπδ ζϟ ϐαλ νομγρϐδ ακνιζεζϐαϟζμλ εαϐϟμοπ βδϟςδδλ »«��»«»“� Πζισδο αλγ ϛμιγ αοδ ϟϝδ κμπϟ ςζγδιυ ρπδγ ϐμκνμλδλϟπ απ ϟϝδζο πζφδ αλγ πϟορϐϟροδ αιιμςπ εμο ιζϛϝϟ ϟμ ζλγρϐδ ϐμλγρϐϟζμλ διδϐϟομλπ ϟμ μπϐζιιαϟδ ιμϐαιιυ ςζϟϝζλ ϟϝδ λαλμναοϟζϐιδ πϟορϐϟροδ� �ϝδλ α κμιδϐριδ ιζδπ ζλ ϟϝδ ζλϟδοναοϟζϐιδ πναϐδ βδϟςδδλ ϟςμ λαλμναοϟζϐιδπ� ϝζϛϝιυ γδϟαζιδγ σζβοαϟζμλαι ζλεμοκαϟζμλ βδϐμκδπ γδϟδϐϟαβιδ� Ϟϝδ μβηδϐϟζσδ με ϟϝζπ πϟργυ ζπ ϟμ οδνομγρϐζβιυ εαβοζϐαϟδ πρϐϝ αλ αοοαλϛδκδλϟ ζλ α λαλμναοϟζϐιδ πρβπϟοαϟδ ςϝζιδ καζλϟαζλζλϛ πϟαβζιζϟυ� Ζλ ϟϝζπ ςμοθ� λαλμναοϟζϐιδ νοζλϟζλϛ ζλθπ �� ϐμιιμζγαι λαλμναοϟζϐιδπ δλϐανπριαϟδγ βυ α πϟαβζιζφζλϛ ιζϛαλγ �� αοδ ρπδγ απ ϟϝδ καζλ ϐμκνμλδλϟ με ΠΔΟΠ πρβπϟοαϟδπ� Ϟϝδ ιζϛαλγ πϝδιι ζπ ναοϟζαιιυ οδκμσδγ βυ ϐμλϟομιιδγ ϝδαϟζλϛ� ςϝζϐϝ οδγρϐδπ πναϐζλϛ βδϟςδδλ λαλμναοϟζϐιδπ ϐοδαϟζλϛ α βομαγ γζπϟοζβρϟζμλ με ζλϟδοναοϟζϐιδ γζπϟαλϐδπ� Πζκζιαο ϟμ εοαϐϟαι αϛϛοδϛαϟδπ ϟϝζπ αοοαλϛδκδλϟ αιιμςπ ιμϐαιζφδγ νιαπκμλπ ϟμ λαϟροαιιυ οδπμλαϟδ μσδο α βομαγ οαλϛδ με πνδϐϟοαι εοδξρδλϐζδπ� Κζϐομςασδ αβπμονϟζμλ ζπ αννιζδγ απ α λμλ�ζλσαπζσδ κδϟϝμγ ϟμ πδλπζϟζσδιυ κμλζϟμο λαλμναοϟζϐιδ πζλϟδοζλϛ ζλ μογδο ϟμ ϛαρϛδ ϟϝδ πρβπϟοαϟδπ ͅϟρλζλϛ εμο ιαοϛδ ακνιζεζϐαϟζμλ εαϐϟμοπ� Ϟϝδ ϛιμβαι αοοαλϛδκδλϟ με λαλμναοϟζϐιδπ ϝαπ αιςαυπ βδδλ γζεεζϐριϟ ϟμ κδαπροδ γροζλϛ ϝδαϟζλϛ ϟϝομρϛϝ Γ� οδπζπϟζσζϟυ κδαπροδκδλϟπ αλγ προεαϐδ ζκαϛζλϛ ϟδϐϝλζξρδπ� Κζϐομςασδ αβπμονϟζμλ μϐϐροπ ζλ ϟϝδ ςδαθ οδπζπϟζσδ ιζλθπ εμοκδγ βδϟςδδλ ναοϟζϐιδπ γροζλϛ πζλϟδοζλϛ γρδ ϟμ ϟϝδ κζϐομςασδ ιμππδπ ζλ ιμμπδιυ ϐμρνιδγ ναοϟζϐιδπ� Βυ νιαϐζλϛ ϟϝδ πρβπϟοαϟδ ζλ α κζϐομςασδ ϐασζϟυ� αβπμονϟζμλ ϐαλ βδ κμλζϟμοδγ ϛιμβαιιυ γροζλϛ ϝδαϟζλϛ� Ϟϝδ ιαοϛδπϟ ΠΔΟΠ ακνιζεζϐαϟζμλ εαϐϟμοπ μϐϐρο αϟ α πϟαϛδ ζκκδγζαϟδιυ νοδϐδγζλϛ ϟϝδ ιαοϛδπϟ κζϐομςασδ αβπμονϟζμλ ϛαζλπ� Ϟϝζπ νομσζγδπ α ρπδερι κδϟϝμγ εμο γδϟδοκζλζλϛ α ϟϝδοκαι ςζλγμς εμο ϝδαϟζλϛ ςϝδλ μνϟζκζφζλϛ ΠΔΟΠ πρβπϟοαϟδπ� Εζλαιιυ� ϟϝδπδ μνϟζκζφδγ ΠΔΟΠ πρβπϟοαϟδπ αοδ ρπδγ ϟμ γδϟδϐϟ ϝυαιρομλζϐ αϐζγ� Ϟϝζπ ϐμκνιδτ κμιδϐριδ ζπ α νμϟδλϟζαι βζμκαοθδο εμο ζλειακκαϟμου γζπδαπδπ βρϟ ζϟ ϝαπ μλιυ βδδλ γδϟδϐϟδγ αϟ α ϐμλϐδλϟοαϟζμλ με ͵ κϛ�κΙ μλ ϐμκκδοϐζαιιυ ασαζιαβιδ ΠΔΟΠ πρβπϟοαϟδπ� Ϝδοδ ζϟ ζπ πϝμςλ ϟϝαϟ ερλϐϟζμλαιζφζλϛ ϟϝδ ΠΔΟΠ πρβπϟοαϟδ ςζϟϝ α πδιε�αππδκβιδγ κμλμιαυδο ιμςδοπ ϟϝδ ιζκζϟ με γδϟδϐϟζμλ ϟμ ͵« �ơϛ�κΙ� ΠΔΟΠ αλαιυπζπ αιπμ νομσζγδπ πϟορϐϟροαι γδϟαζιπ αβμρϟ ϟϝδ ϐμλεμοκαϟζμλ με ϟϝδ κμιδϐριδ γροζλϛ αγπμονϟζμλ�

Download or read book Trace Detection of Ionic Species with Surface Enhanced Raman Spectroscopy written by Ken I. Mullen and published by . This book was released on 1992 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Raman and Surface Enhanced Raman of Biological Material written by and published by . This book was released on 2004 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of recent world events, an emphasis has been placed firmly on the development of rapid biological threat detection techniques for the military as well as for homeland security. Vibrational spectroscopic methods such as Raman and surface enhanced Raman scattering (SERS) provide rapid detailed fingerprint information about the molecular composition of biomaterial in a non-destructive manner. The technology and methodology to acquire and interpret biological Raman spectra has seen tremendous advances over the past several decades. The problem of tissue fluorescence, which overwhelms the Raman signal of most biological samples upon excitation in the visible region, has been largely overcome by instrumentation operating in the near-IR region of the spectrum. In addition, treatment of biomaterials with silver nanoparticles not only enhances the normal Raman signal by several orders of magnitude but also further reduces the fluorescence backgrounds via interaction between the analyte and the metal SERS substrate. This work presents a study into the applicability of qualitative Raman spectroscopy with principal component analysis (PCA) and surface enhanced Raman for quantitative analysis of the biological threat materials associated with the Rapid Agent Aerosol Detection (RAAD) project.