Download or read book Detailed Review Paper Appraisal of Test Methods for Sex Hormone Disrupting Chemicals written by Organisation for Economic Co-operation and Development and published by . This book was released on 2002 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document servesas the basis for the first step in the consideration and development of OECD Test Guidelines for the testing of chemicals for endocrine-disrupting effects. OECD Test Guidelines play a critical role in ensuring that efficient and effective procedures are available to identify chemical hazards. The focus of thispaper is on test methods for sex hormone-disrupting chemicals capable of affecting the reproductive process. Other hormone systems which are also important in the control of reproduction, such as the thyroid and adrenal systems, are not considered. In addition, test methods for the effects of sex hormones on non-reproductive processes such as brain development and behaviour are considered to be beyond the scope of this document. Accordingly, the DRP makes an inventory of existing OECD test methods relevant to the assessment of the effects of sex hormone-disrupters on the reproductive systems of humans and wildlife; describes relevant non-regulatory test methodologies used by the research community; makes a critical assessment of existing test methodologies to detect sex hormone-disrupting chemicals; identifies possible enhancements to existing test methodologies; and identifies both those non-regulatory test methodologies suitable for further development and outstanding research requirements.
Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Detailed Review Paper Appraisal of Test Methods for Sex Hormone Disrupting Chemicals written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This documents servies as the basis for the first step in the consideration and development of OECD Test Guidelines for the testing of chemicals for endocrine-disrupting effects.
Download or read book Draft detailed review paper appraisal of test methods for sex hormone disrupting chemicals written by and published by . This book was released on 1997 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comments on OECD Draft Detailed Review Paper written by European Centre for Ecotoxicology and Toxicology of Chemicals and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book OECD Series on Testing and Assessment Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors written by OECD and published by OECD Publishing. This book was released on 2012-08-21 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper provides methods for both the mechanistic evaluation of the action of Endocrine Disrupter Chemicals (EDCs).
Download or read book OECD Series on Testing and Assessment Detailed Review Paper DRP on Molluscs Life cycle Toxicity Testing written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to EDCs and to other chemicals.
Download or read book OECD Series on Testing and Assessment Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations.
Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Guidance Document on Reporting Summary Information on Environmental Occupational and Consumer Exposure written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document contains guidance for using the summary exposure information reporting formats, which were developed by the OECD Ad Hoc Group on Reporting Summary Exposure Information.
Download or read book Chemical Ecology written by Jorg D. Hardege and published by EOLSS Publications. This book was released on 2009-06-10 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Ecology is a component of Encyclopedia of Chemical Sciences, Engineering and Technology Resources in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The Theme on Chemical Ecology provides the essential aspects of the chemicals involved in the interactions of living organisms. It deals with studies involving defensive chemicals which are utilized to deter potential predators, which may attack a wide variety of species, animal interaction, aquatic ecosystems, chemical ecology and pest management, relation to medicine and pharmaceuticals. This volume is aimed at the following five major target audiences: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers.
Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Repeat Dose Toxicity Studies written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document presents a general guide to the analysis and evaluation of data from studies involving repeated exposures of toxicity test species to pesticides and other chemicals.
Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Guidance Document for the Conduct of Skin Absorption Studies written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 31 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guidance document has been prepared to support technical aspects of the OECD skin absorption test guidelines. In particular is discusses the various aspects of in vivo vs. in vitro testing.
Download or read book OECD Series on Testing and Assessment The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document describes the state of knowledge of the adverse outcome pathway (AOP) for skin sensitisation initiated by covalent binding to proteins, assesses the weight-of-evidence supporting the AOP, identifies the key events, and identifies databases containing test results related to key events.
Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Harmonised Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document sets out the objectives, organisational context, and plan for a Harmonised Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures.
Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Detailed Review Document on Hazard Classification Systems for Mixtures written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document focuses on the health and environmental hazards of mixtures.
Download or read book Series on Pesticides and Biocides Guidance Document on Overview of Residue Chemistry Studies Second Edition written by OECD and published by OECD Publishing. This book was released on 2009-07-28 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Overview Guidance Document summarises the major guidance aspects provided in the OECD Guidelines for the Testing of Chemicals, Section 5. This document also develops an approach for a Global Maximum Residue Limit (MRL) process to achieve use of a single globally acceptable feeding study for MRL setting and risk assessment for livestock food commodities that involves four key components: 1) Harmonised Guidance for the Definition of Residue; 2) Reasonable Worst Case Animal Diets/Maximum Reasonably Balanced Diet; 3) Harmonised Table of Livestock Feed Commodities; and 4) Definition of Reasonable Worst Case Livestock Feeding Levels.
Download or read book Assessment and Management of Environmental Risks written by Igor Linkov and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing environmental contamination requires decision makers to weigh eXlstmg risks against the potential effects of implementing environmental policies - considering both the benefits and disruptions that may result from different actions. The NATO Advanced Research Workshop in Lisbon was an important step in the development and application of cost efficient methods of risk assessment especiaIly within the constraints of a budget. The goal of the workshop was to evaluate the potential for risk assessment to serve as a unified and unifying technique in addressing a wide range of environmental problems. Papers presented in this book discuss issues ranging from specific and local studies (specific site, ecosystem, pollutant) to global decision and management frameworks (watersheds, regions, integration of multiple poIlutants and stressors); they develop a range of approaches starting from specific methods to widely applied public policies (Figure 1). The papers show that the use of risk assessment can provide the scientific basis for environmentaIly sound and cost-efficient policies, strategies, and solutions to our environmental chaIlenges. The organization of the Proceedings reflects sessions and discussions during the workshop. The papers in the introductory Chapter summarize the positions of Drs. Glenn Suter (EPA) and Jim Wilson (Resources for the Future) regarding whether the use of often-expensive risk assessments in developing countries can be justified, given evolving regulatory institutions and limited resources.
Download or read book Endocrine Disrupters written by Polyxeni Nicolopoulou-Stamati and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: During recent decades, millions of tonnes of man-made chemicals have been produced and released into the environment, with very little safety testing. Many of these chemical substances have been found to interfere with the endocrine system and modulate its function. This book not only overviews the effects of endocrine/disrupting substances on human health, but also addresses the regulatory problems from the point of view of international organisations, including the WHO, the EU, and the European Chlorine Industry. This volume contains the proceedings of a workshop held at the International Hippocrates Foundation on Kos Island, Greece, in September 1999. The workshop was part of the activities of the ASPIS project, which aims at raising awareness of environmental health impacts among multidisciplinary groups. The contributions to this volume are the result of the interaction of participants at the workshop. As such, it addresses the issue of endocrine disrupters from many different points of view and allows the subject to be approached by a multidisciplinary readership, including: decision makers, medical doctors, environmental experts, post/and undergraduate students, lawyers, engineers, and journalists.
