Download or read book Designing Microwave Sensors for Glucose Concentration Detection in Aqueous and Biological Solutions written by Carlos G. Juan and published by Springer Nature. This book was released on 2021-06-14 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive study covering the design and application of microwave sensors for glucose concentration detection, with a special focus on glucose concentration tracking in watery and biological solutions. This book is based on the idea that changes in the glucose concentration provoke variations in the dielectric permittivity of the medium. Sensors whose electrical response is sensitive to the dielectric permittivity of the surrounding media should be able to perform as glucose concentration trackers. At first, this book offers an in-depth study of the dielectric permittivity of water–glucose solutions at concentrations relevant for diabetes purposes; in turn, it presents guidelines for designing suitable microwave resonators, which are then tested in both water–glucose solutions and multi-component human blood plasma solutions for their detection ability and sensitivities. Finally, a portable version is developed and tested on a large number of individuals in a real clinical scenario. All in all, the book reports on a comprehensive study on glucose monitoring devices based on microwave sensors. It covers in depth the theoretical background, provides extensive design guidelines to maximize sensitivity, and validates a portable device for applications in clinical settings.

Download or read book Coupled Structures for Microwave Sensing written by Ferran Martín and published by Springer Nature. This book was released on with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues written by Valery V. Tuchin and published by CRC Press. This book was released on 2008-12-22 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although noninvasive, continuous monitoring of glucose concentration in blood and tissues is one of the most challenging areas in medicine, a wide range of optical techniques has recently been designed to help develop robust noninvasive methods for glucose sensing. For the first time in book form, the Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues analyzes trends in noninvasive optical glucose sensing and discusses its impact on tissue optical properties. This handbook presents methods that improve the accuracy in glucose prediction based on infrared absorption spectroscopy, recent studies on the influence of acute hyperglycemia on cerebral blood flow, and the correlation between diabetes and the thermo-optical response of human skin. It examines skin glucose monitoring by near-infrared spectroscopy (NIR), fluorescence-based glucose biosensors, and a photonic crystal contact lens sensor. The contributors also explore problems of polarimetric glucose sensing in transparent and turbid tissues as well as offer a high-resolution optical technique for noninvasive, continuous, and accurate blood glucose monitoring and glucose diffusion measurement. Written by world-renowned experts in biomedical optics and biophotonics, this book gives a complete, state-of-the-art treatise on the design and applications of noninvasive optical methods and instruments for glucose sensing.

Download or read book Design of a Microwave Sensor for Non invasive Determination of Blood glucose Concentration written by Eric C. Green and published by . This book was released on 2005 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is a disease that afflicts millions worldwide. To control the effects of this disease, diabetics must check their blood glucose levels on a regular basis. Currently, all daily glucose monitoring techniques are invasive, requiring a sample of blood. Microwave sensors are non-destructive and non-contact measuring devices, making them ideal for the measurement of parameters in industrial processes. Current uses of microwave sensors range from measuring moisture content of corn chips to measuring concentration of a solute in water. If a microwave sensor were developed to determine blood glucose concentration, it could be the first daily-use glucose-measuring technique that is truly non-invasive. This thesis provides background on diabetes and microwave measurement. From this background, a sensor is developed and its advantages are illustrated. The thesis concludes by making suggestions for improving the sensor and recommendations on how to implement the sensor into a useful product.

Download or read book Glucose Sensing written by Chris D. Geddes and published by Springer Science & Business Media. This book was released on 2007-12-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for any laboratory working in the analytical fluorescence glucose sensing field. The increasing importance of these techniques is typified in one emerging area by developing non-invasive and continuous approaches for physiological glucose monitoring. This volume incorporates analytical fluorescence-based glucose sensing reviews, specialized enough to be attractive to professional researchers, yet appealing to a wider audience of scientists in related disciplines of fluorescence.

Download or read book Calibration Methodology for a Microwave Non invasive Glucose Sensor written by Melanie J. McClung and published by . This book was released on 2008 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-invasive measuring techniques for determining biological parameters are more heavily researched with the growth of the biomedical industry. One of the top areas in non-invasive research deals with diabetes. This disease affects more than 20 million people in the United States, and there is an increasing desire to find a testing process that is non-invasive, easy to use, and safe for users. Microwave technology has improved greatly during recent years and is now seen more often in conjunction with biomedical research. Microwaves are capable of taking measurements of materials inside of a closed volume without the need to come into contact with the material. This makes them ideal for measuring biological parameters, specifically glucose concentrations in the blood. This thesis expands on the development of a microwave sensor to non-invasively measure blood glucose levels and will examine the possibility of developing a calibration for a device using the microwave sensor.

Download or read book Ultrasensitive Microwave Near Field Sensors For Detection Imaging and Material Characterization written by Ali Mohammed Albishi and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Affordable, sensitive, selective, fast-responding, label-free sensors are currently in high demand for many of today's applications and technologies, particularly in the food industry, bio-sensing applications, and quality control. In addition, modern technologies such as a lab-on-a-chip involve microfluidic analysis, which requires highly accurate and miniaturized sensing systems. These systems can be implemented in biomedical applications such as point-of-care diagnostics, as well as in environmental monitoring, agriculture, biotechnology, and public health and safety. A need, therefore, exists for highly accurate and reliable sensing systems that can meet the requirements of these applications. This dissertation presents electrically-small planar microwave resonators for the design of near-field sensors that can satisfy the needs of the aforementioned applications. This thesis proposes a number of novel concepts related to miniaturization and the enhancement of the sensitivity of electrically-small sensors. In the first part of the thesis, an analysis of the sensitivity of complementary split-ring resonators (CSRRs) with respect to changes in resonator topology is presented. Eigenmode solvers, circuit models, numerical simulations, and laboratory measurements were all employed for the analysis. The results show that the resonance frequency is adjustable and scalable. The second part of the thesis proposed an ultrasensitive near-field sensor for detecting submillimeter cracks in metallic materials. Experimental measurements revealed that a surface crack of 200 um wide and 2 mm deep results in a 1.5 GHz shift in the resonance frequency. The results led to the idea of utilizing CSRRs for designing near-field sensors for crack detection in dielectric materials. The work was further extended to increase the sensitivity of planar CSRRs to detect the presence of dielectric materials. This concept is based on increasing the sensing areas per unit length and on the utilization of multiple, identical, and coupled resonators. Although the electromagnetic energy stored in electrically-small planar resonators is concentrated primarily in an electrically-small volume, most of that energy is located in the host substrate, thus limiting the sensitivity required for detecting changes in the material under test (MUT), which differs from the host substrate. For this reason, a sensor designed for enhancing the EM energy stored in the sensing volume that is exposed to the MUT is proposed. The design concept is based on the use of a three-dimensional capacitor. For validation purposes, a complementary electric-LC resonator (CELCR) and two metallic bars were utilized for designing the sensor for dielectric materials. Furthermore, by adopting the concept of three-dimensional capacitors, microwave sensors based on planar SRRs are introduced in order to 1) enhance the sensitivity, 2) allow for flexible tunability, and 3) create novel sensors for fluidic applications. For validation purposes, an SRR-based sensor was designed and tested using numerical simulation and experiments to detect fluid materials and fluid levels. The SRR with the three-dimensional capacitors was also utilized to design probes for the near-field scanning microscopy. An additional component of this research was, therefore, an exploration of the miniaturization of CELCR sensing areas so that these devices could be loaded with three-dimensional capacitors in order to design a sensitive near-field sensor for microscale-based technologies. The ability of the sensor to detect the presence of magnetic materials was also investigated numerically. For applications in which flatness or compactness is a relevant factor, enhancing sensitivity with the use of three-dimensional capacitors is not an ideal solution. Although classical planar antennas such as patch antennas are subject to a lack of EM energy localization in small areas, the adoption of the split concept, utilized in electrically-small resonators, can improve these antennas for use in designing near-field microwave sensors. This thesis proposed a planar microwave sensor based on an annular ring resonator loaded with a split, thus enabling it to operate at lower frequencies and to enhance the quality factors. The sensor was tested experimentally with respect to characterizing dielectric slabs and detecting the presence of fluidic materials. The last part of the thesis introduced the concept of an intelligent sensing technique based on the modulation of the frequency responses of near-field microwave sensors for the characterization of material parameters. The concept is based on the assumption that the physical parameters being extracted are uniform over the frequency range of the sensing system. The concept is derived from the observation of the sensor responses as multidimensional vectors over a wide frequency range. The dimensions are then considered as features for a neural network. The concept has been demonstrated experimentally for the detection of the concentration of a fluid material composed of two pure fluids.

Download or read book Electrochemical Biosensors written by Serge Cosnier and published by CRC Press. This book was released on 2015-01-26 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy

Download or read book Dielectric Relaxation in Biological Systems written by Valerica Raicu and published by OUP Oxford. This book was released on 2015-07-23 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of dielectric properties of biological systems and their components is important not only for fundamental scientific knowledge but also for its applications in medicine, biology, and biotechnology. The associated technique - known as dielectric spectroscopy - has enabled researchers to quickly and accurately acquire time- or frequency-spectra of permittivity and conductivity and permitted the derivation and testing of realistic electrical models for cells and organelles. This text covers the theoretical basis and practical aspects of the study of dielectric properties of biological systems, such as water, electrolyte and polyelectrolytes, solutions of biological macromolecules, cells suspensions and cellular systems. The authors' combined efforts provide a comprehensive and cohesive book that takes advantage of the expertise of multiple scientists involved in cutting-edge research in the specific sub-fields of bio-dielectric spectroscopy while maintaining its self-consistency through numerous discussions. The first six chapters cover theoretical, methodological and experimental aspects of relaxation and dispersion in biological dielectrics at molecular, cellular and cellular aggregate level. Applications are presented in the following chapters which are organized in the order of increased complexity, beginning with pure water, amino acids and proteins, continuing with vesicles and simple cells such as erythrocytes, and then with more complex, organelle-containing cells and cellular aggregates. Due to its broad coverage, the text could be used as a reference book by researchers, and as a textbook for upper-level undergraduate classes and graduate classes in (bio) physics, medical physics, quantitative biology, and engineering.

Download or read book The Development of a Minimally Invasive Glucose Sensing System written by Lisa Ellen Sambol and published by . This book was released on 2000 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Development and Optimization of an Integrated Faraday Modulator and Compensator Design for Continuous Polarimetric Glucose Monitoring written by Brandon William Clarke and published by . This book was released on 2013 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, significant advances have been made in the development of noninvasive polarimetric glucose detection systems, salutary for the treatment of our rapidly increasing diabetic population. This area of research utilizes the aqueous humor as the detection medium for its strong correlation to blood glucose concentration and highlights three major features: the optical activity of glucose, minimal scattering of the medium, and the ability to detect sub-millidegree rotation in polarized light. However, many of the current polarimetric systems are faced with size and cost constraints based on the paramount optical components (e.g., terbium gallium garnet or terbium doped glass) and custom wound inductive coils. As a step toward developing a low cost hand-held design, a miniaturized integrated single-crystal Faraday modulator/compensator (IFMC) has been designed and optimized. This device is capable of replacing the traditional two component arrangement that has been widely reported on in many Faraday-based polarimetric configurations. In this work, an electromagnetic (EM) finite element model (FEM) was developed that can simulate various physical parameters such as geometry, inductance, and orientation of an IFMC with respect to the optical components in order to minimize power consumption and size while maintaining appropriate magnetic field strength. The newly designed prototype was compared with the FEM, providing excellent correlation with operational performance shown to be within 1.8% of predicted values. It was shown that the use of FEM simulations allows for the analysis of a vast range of parameters before prototypes are fabricated and can facilitate custom designs as related to development time, anticipated performance, and cost reduction. Furthermore, the performance of the IFMC was evaluated experimentally under both noninvasive static and dynamic glucose monitoring conditions with a custom designed glucose flow system. The dynamic flow system provides a repeatable and controllable testing environment which can recreate in vivo glucose profiles while reducing the need for repetitive, expensive, and time consuming animal experiments. Finally, it was shown that the combined rotator can achieve modulation depths above 1°, and when operating in a compensated closed-loop configuration, it had demonstrated glucose prediction errors of 1.8 mg/dL and 5.4 mg/dL under hypoglycemic and hyperglycemic conditions, respectively. These results demonstrate that such an integrated design can perform similar to, if not better than, its larger two-part predecessors. Overall, this technology is capable of expediting future research and development in providing a fully functional and commercially available noninvasive polarimetric glucose sensor.

Download or read book Microwave Systems and Applications written by Sotirios Goudos and published by BoD – Books on Demand. This book was released on 2017-01-11 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microwave systems are key components of every modern wireless communication system. The main objective of this book was to collect as many different state-of-the-art studies as possible in order to cover in a single volume the main aspects of microwave systems and applications. This book contains 17 chapters written by acknowledged experts, researchers, academics, and microwave engineers, providing comprehensive information and covering a wide range of topics on all aspects of microwave systems and applications. This book is divided into four parts. The first part is devoted to microwave components. The second part deals with microwave ICs and innovative techniques for on-chip antenna design. The third part presents antenna design cases for microwave systems. Finally, the last part covers different applications of microwave systems.

Download or read book Combinatorial Methods for Chemical and Biological Sensors written by Radislav A. Potyrailo and published by Springer Science & Business Media. This book was released on 2009-03-21 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical sensors are in high demand for applications as varied as water pollution detection, medical diagnostics, and battlefield air analysis. Designing the next generation of sensors requires an interdisciplinary approach. The book provides a critical analysis of new opportunities in sensor materials research that have been opened up with the use of combinatorial and high-throughput technologies, with emphasis on experimental techniques. For a view of component selection with a more computational perspective, readers may refer to the complementary volume of Integrated Analytical Systems edited by M. Ryan et al., entitled “Computational Methods for Sensor Material Selection”.

Download or read book Miniaturized Analytical Devices written by Suresh Kumar Kailasa and published by John Wiley & Sons. This book was released on 2021-12-28 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Miniaturized Analytical Devices An in-depth overview of integrating functionalized nanomaterials with mass spectrometry, spectroscopy, electrophoresis, and other important analytical techniques Miniaturized Analytical Devices: Materials and Technology is an up-to-date resource exploring the analytical applications of miniaturized technology in areas such as clinical microbiology, pharmaceuticals, agriculture, and environmental analysis. The book covers the integration of functional nanomaterials in mass spectrometry, microscopy, electrophoresis, and more—providing the state-of-the-art information required for successfully implementing a range of chemical analysis techniques on microchips. Featuring contributions from a panel of international experts in the field, the book begins with an introduction to selected miniaturized devices, nanomaterials, and analytical methods. Subsequent sections describe functionalized nanomaterials (FNMs) for miniaturized devices and discuss techniques such as miniaturized mass spectrometry for bioassays and miniaturized microscopy for cell imaging. The book concludes by exploring a variety of applications of miniaturized devices in areas including metal analysis, bioimaging, DNA separation and analysis, molecular biology, and more. This timely volume: Surveys the current state of the field and provides a starting point for developing faster, more reliable, and more selective analytical devices Focuses on the practical applications of miniaturized analytical devices in materials science, clinical microbiology, the pharmaceutical industry, and environmental analysis Covers a wide range of materials and analytical techniques such as microvolume UV-VIS spectroscopy, microchip and capillary electrophoresis, and matrix assisted laser desorption ionization-mass spectrometry (MALDI-MS) analysis Discusses the role of miniaturized analytical devices in securing a green and sustainable future Miniaturized Analytical Devices: Materials and Technology is essential reading for analytical chemists, analytical laboratories, materials scientists, biologists, life scientists, and advanced students in related fields.

Download or read book Nanobiosensors written by Alexandru Grumezescu and published by Academic Press. This book was released on 2016-09-28 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanobiosensors: Nanotechnology in the Agri-Food Industry, Volume 8, provides the latest information on the increasing demand for robust, rapid, inexpensive, and safe alternative technologies that monitor, test, and detect harmful or potentially dangerous foods. Due to their high sensitivity and selectivity, nanobiosensors have attracted attention for their use in monitoring not only biological contaminants in food, but also potential chemical and physical hazards. This book offers a broad overview regarding the current progress made in the field of nanosensors, including cutting-edge technological progress and the impact of these devices on the food industry. Special attention is given to the detection of microbial contaminants and harmful metabolotes, such as toxins and hormones, which have a great impact on both humans and animal health and feed. - Includes the most up-to-date information on nanoparticles based biosensors and quantum dots for biological detection - Provides application methods and techniques for research analysis for bacteriological detection and food testing - Presents studies using analytical tools to improve food safety and quality analysis

Download or read book Nanotechnology Enabled Sensors written by Kourosh Kalantar-zadeh and published by Springer Science & Business Media. This book was released on 2007-09-19 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology provides tools for creating functional materials, devices, and systems by controlling materials at the atomic and molecular scales and making use of novel properties and phenomena. Nanotechnology-enabled sensors find applications in several fields such as health and safety, medicine, process control and diagnostics. This book provides the reader with information on how nanotechnology enabled sensors are currently being used and how they will be used in the future in such diverse fields as communications, building and facilities, medicine, safety, and security, including both homeland defense and military operations.

Download or read book Metal Nanoclusters in Catalysis and Materials Science The Issue of Size Control written by Benedetto Corain and published by Elsevier. This book was released on 2011-08-11 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal Nanoclusters in Catalysis and Materials Science: The Issue of Size Control deals with the synthesis of metal nanoclusters along all known methodologies. Physical and chemical properties of metal nanoclusters relevant to their applications in chemical processing and materials science are covered thoroughly. Special attention is given to the role of metal nanoclusters size and shape in catalytic processes and catalytic applications relevant to industrial chemical processing.An excellent text for expanding the knowledge on the chemistry and physics of metal nanoclusters. Divided in two parts; Part I deals with general aspects of the matter and Part II has to be considered a useful handbook dealing with the production of metal nanoclusters, especially from their size-control point of view.* Divided into two parts for ease of reference: general and operational * Separation of synthetic aspects, physical properties and applications* Specific attention is given to the task of metal nanoclusters size-control