Download or read book Foundations of Epidemiology written by Marit L. Bovbjerg and published by . This book was released on 2020-10 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foundations of Epidemiology is an open access, introductory epidemiology text intended for students and practitioners in public or allied health fields. It covers epidemiologic thinking, causality, incidence and prevalence, public health surveillance, epidemiologic study designs and why we care about which one is used, measures of association, random error and bias, confounding and effect modification, and screening. Concepts are illustrated with numerous examples drawn from contemporary and historical public health issues.

Download or read book Marine Structural Design Calculations written by Mohamed A. El-Reedy and published by Butterworth-Heinemann. This book was released on 2014-09-30 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: The perfect guide for veteran structural engineers or for engineers just entering the field of offshore design and construction, Marine Structural Design Calculations offers structural and geotechnical engineers a multitude of worked-out marine structural construction and design calculations. Each calculation is discussed in a concise, easy-to-understand manner that provides an authoritative guide for selecting the right formula and solving even the most difficult design calculation. Calculation methods for all areas of marine structural design and construction are presented and practical solutions are provided. Theories, principles, and practices are summarized. The concentration focuses on formula selection and problem solving. A “quick look up guide , Marine Structural Design Calculations includes both fps and SI units and is divided into categories such as Project Management for Marine Structures; Marine Structures Loads and Strength; Marine Structure Platform Design; and Geotechnical Data and Pile Design. The calculations are based on industry code and standards like American Society of Civil Engineers and American Society of Mechanical Engineers, as well as institutions like the American Petroleum Institute and the US Coast Guard. Case studies and worked examples are included throughout the book. Calculations are based on industry code and standards such as American Society of Civil Engineers and American Society of Mechanical Engineers Complete chapter on modeling using SACS software and PDMS software Includes over 300 marine structural construction and design calculations Worked-out examples and case studies are provided throughout the book Includes a number of checklists, design schematics and data tables

Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Download or read book Adequacy of Sample Size in Health Studies written by Stanley Lemeshow and published by Wiley. This book was released on 1990-01-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical rather than theoretical, it provides epidemiologists and other health workers with a good basic knowledge of sampling principles and methods and their potential in the medical field. Focusing on the determination of adequate sample sizes under different situations, the book is divided into two parts; the first provides solutions to typical problems of various survey and study designs, and the second offers a clear, concise exposition of the theory behind the processes of determining sample size. Features many reference tables.

Download or read book Sample Size Calculations in Clinical Research written by Shein-Chung Chow and published by CRC Press. This book was released on 2003-03-04 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sample size calculation plays an important role in clinical research. It is not uncommon, however, to observe discrepancies among study objectives (or hypotheses), study design, statistical analysis (or test statistic), and sample size calculation. Focusing on sample size calculation for studies conducted during the various phases of clinical research and development, Sample Size Calculation in Clinical Research explores the causes of discrepancies and how to avoid them. This volume provides formulas and procedures for determination of sample size required not only for testing equality, but also for testing non-inferiority/superiority, and equivalence (similarity) based on both untransformed (raw) data and log-transformed data under a parallel-group design or a crossover design with equal or unequal ratio of treatment allocations. It contains a comprehensive and unified presentation of statistical procedures for sample size calculation that are commonly employed at various phases of clinical development. Each chapter includes, whenever possible, real examples of clinical studies from therapeutic areas such as cardiovascular, central nervous system, anti-infective, oncology, and women's health to demonstrate the clinical and statistical concepts, interpretations, and their relationships and interactions. The book highlights statistical procedures for sample size calculation and justification that are commonly employed in clinical research and development. It provides clear, illustrated explanations of how the derived formulas and/or statistical procedures can be used.

Download or read book Mark s Calculations For Machine Design written by Thomas H. Brown and published by McGraw Hill Professional. This book was released on 2005-02-24 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everyday Engineers must solve some of the most difficult design problems and often with little time and money to spare. It was with this in mind that this book was designed. Based on the best selling Mark’s Standard Handbook for Mechanical Engineers, Mark’s Standard Engineering Calculations For Machine Design offers a detailed treatment of topics in statics, friction, kinematics, dynamics, energy relations, impulse and momentum, systems of particles, variable mass systems, and three-dimensional rigid body analysis. Among the advanced topics are spherical coordinates, shear modulus tangential unit vector tension, deformable media, and torsion (twisting).

Download or read book Encyclopedia of Research Design written by Neil J. Salkind and published by SAGE. This book was released on 2010-06-22 with total page 1779 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Comprising more than 500 entries, the Encyclopedia of Research Design explains how to make decisions about research design, undertake research projects in an ethical manner, interpret and draw valid inferences from data, and evaluate experiment design strategies and results. Two additional features carry this encyclopedia far above other works in the field: bibliographic entries devoted to significant articles in the history of research design and reviews of contemporary tools, such as software and statistical procedures, used to analyze results. It covers the spectrum of research design strategies, from material presented in introductory classes to topics necessary in graduate research; it addresses cross- and multidisciplinary research needs, with many examples drawn from the social and behavioral sciences, neurosciences, and biomedical and life sciences; it provides summaries of advantages and disadvantages of often-used strategies; and it uses hundreds of sample tables, figures, and equations based on real-life cases."--Publisher's description.

Download or read book Design of Mechanical Elements written by Bart Raeymaekers and published by John Wiley & Sons. This book was released on 2022-01-25 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a student-friendly approach for building the skills required to perform mechanical design calculations Design of Mechanical Elements offers an accessible introduction to mechanical design calculations. Written for students encountering the subject for the first time, this concise textbook focuses on fundamental concepts, problem solving, and methodical calculations of common mechanical components, rather than providing a comprehensive treatment of a wide range of components. Each chapter contains a brief overview of key terminology, a clear explanation of the physics underlying the topic, and solution procedures for typical mechanical design and verification problems. The textbook is divided into three sections, beginning with an overview of the mechanical design process and coverage of basic design concepts including material selection, statistical considerations, tolerances, and safety factors. The next section discusses strength of materials in the context of design of mechanical elements, illustrating different types of static and dynamic loading problems and their corresponding failure criteria. In the concluding section, students learn to combine and apply these concepts and techniques to design specific mechanical elements including shafts, bolted and welded joints, bearings, and gears. Provides a systematic “recipe” students can easily apply to perform mechanical design calculations Illustrates theoretical concepts and procedures for solving mechanical design problems with numerous solved examples Presents easy-to-understand explanations of the considerations and assumptions central to mechanical design Includes end-of-chapter practice problems that strengthen the understanding of calculation techniques Supplying the basic skills and knowledge necessary for methodically performing basic mechanical design calculations, Design of Mechanical Elements: A Concise Introduction to Mechanical Design Considerations and Calculations is the perfect primary textbook for single-semester undergraduate mechanical design courses.

Download or read book Principles of Research Design and Drug Literature Evaluation written by Rajender R. Aparasu and published by Jones & Bartlett Publishers. This book was released on 2014-03-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Research Design and Drug Literature Evaluation is a unique resource that provides a balanced approach covering critical elements of clinical research, biostatistical principles, and scientific literature evaluation techniques for evidence-based medicine. This accessible text provides comprehensive course content that meets and exceeds the curriculum standards set by the Accreditation Council for Pharmacy Education (ACPE). Written by expert authors specializing in pharmacy practice and research, this valuable text will provide pharmacy students and practitioners with a thorough understanding of the principles and practices of drug literature evaluation with a strong grounding in research and biostatistical principles. Principles of Research Design and Drug Literature Evaluation is an ideal foundation for professional pharmacy students and a key resource for pharmacy residents, research fellows, practitioners, and clinical researchers. FEATURES * Chapter Pedagogy: Learning Objectives, Review Questions, References, and Online Resources * Instructor Resources: PowerPoint Presentations, Test Bank, and an Answer Key * Student Resources: a Navigate Companion Website, including Crossword Puzzles, Interactive Flash Cards, Interactive Glossary, Matching Questions, and Web Links From the Foreword: "This book was designed to provide and encourage practitioner’s development and use of critical drug information evaluation skills through a deeper understanding of the foundational principles of study design and statistical methods. Because guidance on how a study’s limited findings should not be used is rare, practitioners must understand and evaluate for themselves the veracity and implications of the inherently limited primary literature findings they use as sources of drug information to make evidence-based decisions together with their patients. The editors organized the book into three supporting sections to meet their pedagogical goals and address practitioners’ needs in translating research into practice. Thanks to the editors, authors, and content of this book, you can now be more prepared than ever before for translating research into practice." L. Douglas Ried, PhD, FAPhA Editor-in-Chief Emeritus, Journal of the American Pharmacists Association Professor and Associate Dean for Academic Affairs, College of Pharmacy, University of Texas at Tyler, Tyler, Texas

Download or read book How to Practice Academic Medicine and Publish from Developing Countries written by Samiran Nundy and published by Springer Nature. This book was released on 2021-10-23 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an open access book. The book provides an overview of the state of research in developing countries – Africa, Latin America, and Asia (especially India) and why research and publications are important in these regions. It addresses budding but struggling academics in low and middle-income countries. It is written mainly by senior colleagues who have experienced and recognized the challenges with design, documentation, and publication of health research in the developing world. The book includes short chapters providing insight into planning research at the undergraduate or postgraduate level, issues related to research ethics, and conduct of clinical trials. It also serves as a guide towards establishing a research question and research methodology. It covers important concepts such as writing a paper, the submission process, dealing with rejection and revisions, and covers additional topics such as planning lectures and presentations. The book will be useful for graduates, postgraduates, teachers as well as physicians and practitioners all over the developing world who are interested in academic medicine and wish to do medical research.

Download or read book Free Energy Calculations in Rational Drug Design written by M. Rami Reddy and published by Springer Science & Business Media. This book was released on 2001-12-31 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free energy calculations represent the most accurate computational method available for predicting enzyme inhibitor binding affinities. Advances in computer power in the 1990s enabled the practical application of these calculations in rationale drug design. This book represents the first comprehensive review of this growing area of research and covers the basic theory underlying the method, numerous state of the art strategies designed to improve throughput and dozen examples wherein free energy calculations were used to design and evaluate potential drug candidates.

Download or read book Project Studies and Design Calculations for Proposed Aircraft of Short Brothers written by Cyril Weeden and published by . This book was released on 1937 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Developing a Protocol for Observational Comparative Effectiveness Research A User s Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Download or read book Sample Size Calculations in Clinical Research written by Shein-Chung Chow and published by CRC Press. This book was released on 2017-08-15 with total page 825 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the Second Edition: "... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics "This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered ..." – Journal of the Royal Statistical Society Sample Size Calculations in Clinical Research, Third Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation. Features: Compares the relative merits and disadvantages of statistical methods for sample size calculations Explains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages Presents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women’s health Provides sample size calculations for dose response studies, microarray studies, and Bayesian approaches This new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation.

Download or read book Cost Justifying Usability written by Randolph G. Bias and published by Morgan Kaufmann. This book was released on 2005-04-04 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advice from the experts on how to justify time and money spent on usability!

Download or read book Calculation and Design of Two dimensional Thermoelectric and Piezoelectric Materials written by San-Dong Guo and published by Frontiers Media SA. This book was released on 2023-08-25 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fascinating two-dimensional (2D) materials are being unconsciously applied in various fields from science to engineering, which is benefited from the glamorous physical and chemical properties of mechanics, optics, electronics, and magnetism. The representative 2D thermoelectric/piezoelectric materials can directly convert thermal/mechanical energy into electrical energy, which can resolve the energy issues and avoid further environmental deterioration. The thermoelectric or piezoelectric properties of various 2D materials, such as graphene, hexagonal boron nitride, black phosphorus, transition metal dichalcogenides (TMDs), arsenene, metal carbides and nitrides (MXenes), and so on, have been investigated in detail. Although tremendous progress has been achieved in the past few years, these properties still need to be improved for their practical application by designing new 2D materials, strain engineering, chemical functionalization, etc. In addition to this, in 2D materials, there are many other novel physical properties, such as magnetism, topology, valley, and so on. The combination of thermoelectricity/piezoelectricity with other unique properties may lead to novel device applications or scientific breakthroughs in new physics. Overall, the emergence of 2D thermoelectric and piezoelectric materials has expanded energy conversion research dramatically. By combing this new device concept with the novel 2D materials, original devices should have potential applications in energy harvesting.

Download or read book A First Course in the Design of Experiments written by John H. Skillings and published by CRC Press. This book was released on 1999-11-24 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most texts on experimental design fall into one of two distinct categories. There are theoretical works with few applications and minimal discussion on design, and there are methods books with limited or no discussion of the underlying theory. Furthermore, most of these tend to either treat the analysis of each design separately with little attempt to unify procedures, or they will integrate the analysis for the designs into one general technique. A First Course in the Design of Experiments: A Linear Models Approach stands apart. It presents theory and methods, emphasizes both the design selection for an experiment and the analysis of data, and integrates the analysis for the various designs with the general theory for linear models. The authors begin with a general introduction then lead students through the theoretical results, the various design models, and the analytical concepts that will enable them to analyze virtually any design. Rife with examples and exercises, the text also encourages using computers to analyze data. The authors use the SAS software package throughout the book, but also demonstrate how any regression program can be used for analysis. With its balanced presentation of theory, methods, and applications and its highly readable style, A First Course in the Design of Experiments proves ideal as a text for a beginning graduate or upper-level undergraduate course in the design and analysis of experiments.