Download or read book Design of a Dual Modality PET Cone Beam CT Scanner written by Predrag Sukovic and published by . This book was released on 2003 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Imaging written by Brian D. Ross and published by Academic Press. This book was released on 2021-08-03 with total page 1872 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. - The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data - Concepts illustrated with over 600 color figures and molecular-imaging examples - Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development - This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications - Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented - This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications
Download or read book Molecular Imaging in Oncology written by Martin G. Pomper and published by CRC Press. This book was released on 2008-10-13 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: With molecular imaging becoming one the fastest growing topics in medical schools, Informa Healthcare presents Molecular Imaging in Oncology, the first comprehensive reference on molecular imaging in oncology.Giving clinicians and researchers a greater understanding of the current field, this text covers:instrumentation and techniquescancer imaging
Download or read book Dual Modality CT SPECT Scanner for Small Animal Imaging written by Alexander Vyacheslavovich Stolin and published by . This book was released on 2007 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work describes the design and performance of a dual-modality system for small animal imaging combining a high spatial resolution SPECT component with an x-ray CT component. All components are mounted on a barrel type gantry which is able to rotate in 0.001 degrees increments about the animal. The SPECT subsystem consists of a four custom-built gamma cameras. The cameras can be equipped with either parallel hole or pinhole collimators depending on the study in question. The cameras can be operated in pairs to implement a unique half-cone geometry setup in order to decrease the overall acquisition time as well as maximize spatial resolution. The intrinsic spatial and energy resolutions of the gamma detectors are measured to be 1.75 mm and 17.9% respectively. Novel type of pinhole collimators was introduced. Square shape aperture with pyramid shape acceptance volume collimator was characterized both theoretically and experimentally. This type of a collimator allows for about 23% of efficiency increase without significant reduction in spatial resolution. The x-ray CT subsystem combines various interchangeable microfocus x-ray sources with either a high resolution CCD based detector or a flat panel Hamamatsu C7940 CMOS array. The CCD detector employs a 7k by 4k Phillips CCD chip with dimensions of 5 cm x 9 cm, large enough to require no minification between the gadolinium oxysulfate phosphor and the chip. The both subsystems have been installed and successfully used in phantom imaging and in a variety of small animal studies. Spatial resolutions of 50 mum for CT and 0.9 mm for SPECT have been achieved for live animal imaging. The scanner is able to obtain a lower resolution CT set in 4.5 minutes and SPECT data set in 30 minutes.
Download or read book Molecular Imaging of Small Animals written by Habib Zaidi and published by Springer. This book was released on 2014-05-27 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development. In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology and pathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.
Download or read book Design and Application of a Dual modality Small Animal SPECT and Micro CT System written by Christian Wietholt and published by . This book was released on 2004 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Imaging written by Ralph Weissleder and published by PMPH-USA. This book was released on 2010 with total page 1384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.
Download or read book Handbook of Particle Detection and Imaging written by Claus Grupen and published by Springer Science & Business Media. This book was released on 2012-01-08 with total page 1251 pages. Available in PDF, EPUB and Kindle. Book excerpt: The handbook centers on detection techniques in the field of particle physics, medical imaging and related subjects. It is structured into three parts. The first one is dealing with basic ideas of particle detectors, followed by applications of these devices in high energy physics and other fields. In the last part the large field of medical imaging using similar detection techniques is described. The different chapters of the book are written by world experts in their field. Clear instructions on the detection techniques and principles in terms of relevant operation parameters for scientists and graduate students are given.Detailed tables and diagrams will make this a very useful handbook for the application of these techniques in many different fields like physics, medicine, biology and other areas of natural science.
Download or read book Handbook of X ray Imaging written by Paolo Russo and published by CRC Press. This book was released on 2017-12-14 with total page 1477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing chapter contributions from over 130 experts, this unique publication is the first handbook dedicated to the physics and technology of X-ray imaging, offering extensive coverage of the field. This highly comprehensive work is edited by one of the world’s leading experts in X-ray imaging physics and technology and has been created with guidance from a Scientific Board containing respected and renowned scientists from around the world. The book's scope includes 2D and 3D X-ray imaging techniques from soft-X-ray to megavoltage energies, including computed tomography, fluoroscopy, dental imaging and small animal imaging, with several chapters dedicated to breast imaging techniques. 2D and 3D industrial imaging is incorporated, including imaging of artworks. Specific attention is dedicated to techniques of phase contrast X-ray imaging. The approach undertaken is one that illustrates the theory as well as the techniques and the devices routinely used in the various fields. Computational aspects are fully covered, including 3D reconstruction algorithms, hard/software phantoms, and computer-aided diagnosis. Theories of image quality are fully illustrated. Historical, radioprotection, radiation dosimetry, quality assurance and educational aspects are also covered. This handbook will be suitable for a very broad audience, including graduate students in medical physics and biomedical engineering; medical physics residents; radiographers; physicists and engineers in the field of imaging and non-destructive industrial testing using X-rays; and scientists interested in understanding and using X-ray imaging techniques. The handbook's editor, Dr. Paolo Russo, has over 30 years’ experience in the academic teaching of medical physics and X-ray imaging research. He has authored several book chapters in the field of X-ray imaging, is Editor-in-Chief of an international scientific journal in medical physics, and has responsibilities in the publication committees of international scientific organizations in medical physics. Features: Comprehensive coverage of the use of X-rays both in medical radiology and industrial testing The first handbook published to be dedicated to the physics and technology of X-rays Handbook edited by world authority, with contributions from experts in each field
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2008 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Webb s Physics of Medical Imaging written by M Flower and published by Taylor & Francis. This book was released on 2016-02-03 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the best-selling, highly acclaimed first edition, the technology and clinical applications of medical imaging have changed significantly. Gathering these developments into one volume, Webb's Physics of Medical Imaging, Second Edition presents a thorough update of the basic physics, modern technology and many examples of cli
Download or read book Handbook of Small Animal Imaging written by George C. Kagadis and published by CRC Press. This book was released on 2018-09-03 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.
Download or read book Dual energy Cone beam CT for Proton Therapy written by Gloria Vilches Freixas and published by . This book was released on 2019 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proton therapy is a promising radiation treatment modality that uses proton beams to treat cancer. Current treatment planning systems rely on an X-ray computed tomography (CT) image of the patient's anatomy to design the treatment plan. The proton stopping-power ratio relative to water (SPR) is derived from CT numbers (HU) to compute the absorbed dose in the patient. Protons are more vulnerable than photons to changes in tissue SPR in the beam direction caused by movement, misalignment or anatomical changes. In addition, inaccuracies arising from the planning CT and intrinsic to the HU-SPR conversion greatly contribute to the proton range uncertainty. In clinical practice, safety margins are added to the treatment volume to account for these uncertainties at the expense of losing organ-sparing capabilities. The use of dual-energy (DE) in proton therapy was first suggested in 2009 to better estimate the SPR with respect to single-energy X-ray imaging. The aim of this thesis work is to investigate the potential improvement in determining proton SPR using DE to reduce the uncertainty in predicting the proton range in the patient. This PhD work is applied to a new imaging device, the Imaging Ring (IR), which is a cone-beam CT (CBCT) scanner developed for image-guided radiotherapy (IGRT). The IR is equipped with a fast kV switching X-ray source, synchronized with a filter wheel, allowing for multi-energy CBCT imaging. The first contribution of this thesis is a method to calibrate a model for the X-ray source and the detector response to be used in X-ray image simulations. It has been validated experimentally on three CBCT scanners. Secondly, the investigations have evaluated the factors that have an impact on the outcome of the DE decomposition process, from the acquisition parameters to the post-processing. Both image- and projection-based decomposition domains have been thoroughly investigated, with special emphasis on projection-based approaches. Two novel DE decomposition bases have been proposed to estimate proton SPRs, without the need for an intermediate variable such as the effective atomic number. The last part of the thesis proposes an estimation of proton SPR maps of tissue characterization and anthropomorphic phantoms through DE-CBCT acquisitions with the IR. A correction for X-ray scattering has been implemented off-line, and a routine to linearly interpolate low-energy and high-energy sinograms from sequential and fast-switching DE acquisitions has been proposed to perform DE material decomposition in the projection domain with real data. DECT-derived SPR values have been compared with experimentally-determined SPR values in a carbon-ion beam.
Download or read book Essentials of In Vivo Biomedical Imaging written by Simon R. Cherry and published by CRC Press. This book was released on 2016-02-17 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: While there are many excellent texts focused on clinical medical imaging, there are few books that approach in vivo imaging technologies from the perspective of a scientist or physician-scientist using, or interested in using, these techniques in research. It is for these individuals that Essentials of In Vivo Biomedical Imaging is written.Featurin
Download or read book Tomosynthesis Imaging written by Ingrid Reiser and published by Taylor & Francis. This book was released on 2016-04-19 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: An innovative, three-dimensional x-ray imaging technique that enhances projection radiography by adding depth resolution, Tomosynthesis Imaging explores tomosynthesis, an emerging limited-angle tomographic imaging technology that is being considered for use in a range of clinical applications, and is currently being used for breast cancer screening
Download or read book Clinical PET CT in Radiology written by Paul Shreve and published by Springer Science & Business Media. This book was released on 2010-12-14 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is specifically designed to meet the needs of practicing radiologists by offering a practical, unified approach to PET-CT. It details how to effectively apply PET-CT in patient management. Written by radiologists who fully appreciate and understand both PET and CT, the book details an integrated understanding of PET-CT as a combined modality. Clinical topics include PET-CT of thoracic malignancies, melanoma, and breast cancer. In addition, the book reinforces fundamental concepts, such as the role of imaging diagnosis in disease management.
Download or read book The Journal of Nuclear Medicine written by and published by . This book was released on 2008 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
