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Book Derivatives of Piperazine and Morpholine I

Download or read book Derivatives of Piperazine and Morpholine I written by Vincent Evans Stewart and published by . This book was released on 1937 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Synthesis and Evaluation of Substituted Morpholine and Bis piperazine Aminosulfonic Acid Derivatives for Use as Biological Buffers

Download or read book Synthesis and Evaluation of Substituted Morpholine and Bis piperazine Aminosulfonic Acid Derivatives for Use as Biological Buffers written by Daniel Kwadwo Dei and published by . This book was released on 2005 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book A Text book of Medicine

Download or read book A Text book of Medicine written by Charles Hilton Fagge and published by . This book was released on 1901 with total page 1154 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Emergency Response Guidebook

Download or read book Emergency Response Guidebook written by U.S. Department of Transportation and published by Simon and Schuster. This book was released on 2013-06-03 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does the identification number 60 indicate a toxic substance or a flammable solid, in the molten state at an elevated temperature? Does the identification number 1035 indicate ethane or butane? What is the difference between natural gas transmission pipelines and natural gas distribution pipelines? If you came upon an overturned truck on the highway that was leaking, would you be able to identify if it was hazardous and know what steps to take? Questions like these and more are answered in the Emergency Response Guidebook. Learn how to identify symbols for and vehicles carrying toxic, flammable, explosive, radioactive, or otherwise harmful substances and how to respond once an incident involving those substances has been identified. Always be prepared in situations that are unfamiliar and dangerous and know how to rectify them. Keeping this guide around at all times will ensure that, if you were to come upon a transportation situation involving hazardous substances or dangerous goods, you will be able to help keep others and yourself out of danger. With color-coded pages for quick and easy reference, this is the official manual used by first responders in the United States and Canada for transportation incidents involving dangerous goods or hazardous materials.

Book Synthesis of Best Seller Drugs

Download or read book Synthesis of Best Seller Drugs written by Ruben Vardanyan and published by Academic Press. This book was released on 2016-01-07 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation

Book Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Download or read book Green Approaches in Medicinal Chemistry for Sustainable Drug Design written by Bimal Krishna Banik and published by Elsevier. This book was released on 2024-05-31 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive experimentation and high failure rates are a well-recognized downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry 2e reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry, Second Edition encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This second volume of the second edition includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods. Highlights the need for adoption of sustainable and green chemistry pathways in drug development Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability

Book Catalysis from A to Z

Download or read book Catalysis from A to Z written by Boy Cornils and published by John Wiley & Sons. This book was released on 2020-01-13 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a complete and accessible A to Z collection of information on catalysis This updated and enlarged must-have edition of a classic book on catalysis explains the important terms of all aspects of the subject - including biocatalysis, homogeneous catalysis, heterogeneous catalysis - as well as the terms associated with it. It also looks at related topics like spectroscopy or analytical methods. Featuring 20% more content than the previous edition, it comprehensively covers the topic in a clear and concise manner, and includes abbreviations, brief biographic entries of important scientists who have worked in catalysis, trade names, important catalytic processes, named reactions, reactions, and other important keywords in the general field of catalysis. Written by more than 200 top scientists and with more than 15,000 entries on all aspects of catalysis, Catalysis from A to Z: A Concise Encyclopedia, 5th Edition is filled with figures, tables, cross-references, and references. It covers acids, ligands, catalytic reactions in organic synthesis, kinetics and thermodynamics of catalytic reactions, and catalyst labeling. The book also looks at theoretical backgrounds of catalytic reactions, industrial catalytic processes, autoclaves, colloids, nanomaterials, spectroscopically methods for catalyst analysis, and more. Provides all the knowledge scientists need to know about homogeneous, heterogeneous, and biochemical catalysis Includes more than 15,000 keywords in compact entries Newly updated and expanded edition of the bestselling classic Comprehensive, succinct, and easy to use Edited by an experienced team of top editors and authors with contributions from over 200 scientific experts Offers German and French translations of the keywords to help students and non-native English speakers Catalysis from A to Z: A Concise Encyclopedia is an ideal resource for every student, chemist, scientist, and engineer involved in catalytic chemistry, chemical engineering, biochemistry, organic chemistry, and more.

Book Structural Correlates of Carcinogenesis and Mutagenesis

Download or read book Structural Correlates of Carcinogenesis and Mutagenesis written by Irvin M. Asher and published by . This book was released on 1978 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Solid Phase Peptide Synthesis

Download or read book Solid Phase Peptide Synthesis written by Gregg B. Fields and published by Academic Press. This book was released on 1997-10-21 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volumehas been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 275 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchers in all fields of life sciences. Key Features * Solid-phase peptide synthesis * Applications of peptides for structural and biological studies * Characterization of synthetic peptides

Book Applied Biocatalysis

    Book Details:
  • Author : John Whittall
  • Publisher : John Wiley & Sons
  • Release : 2020-08-21
  • ISBN : 111948703X
  • Pages : 560 pages

Download or read book Applied Biocatalysis written by John Whittall and published by John Wiley & Sons. This book was released on 2020-08-21 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides clear and comprehensive coverage of recently developed applied biocatalysis for synthetic organic chemists with an emphasis to promote green chemistry in pharmaceutical and process chemistry This book aims to make biocatalysis more accessible to both academic and industrial synthetic organic chemists. It focuses on current topics within the applied industrial biocatalysis field and includes short but detailed experimental methods on timely novel biocatalytic transformations using new enzymes or new methodologies using known enzymes. The book also features reactions that are “expanding and making the enzyme toolbox available to chemists”—providing readers with comprehensive methodology and detailed key sourcing information of a wide range of enzymes. Chapters in Applied Biocatalysis: The Chemist’s Enzyme Toolkit are organized by reaction type and feature a short introductory section describing the current state of the art for each example. Much of the book focuses on processes for which the enzymes are readily available so that organic chemists can synthesize appropriate quantities of chemicals with available materials in a standard chemical laboratory. Advanced methods are included to present examples of new enzymes that might encourage collaboration with suppliers or academic groups and that will educate chemists of rapidly expanding future possibilities. Focuses on current topics within the applied industrial biocatalysis field Offers experimental methods on novel biocatalytic transformations using new enzymes or new methodology using known enzymes Covers the hot topics of enzyme and chemoenzymatic cascades and biocatalysis in flow Edited by noted experts from both academia and industry with years of experience in the field of biocatalysis—particularly, the industrial applications of enzymes Written for synthetic organic chemists working in all industries but especially the pharmaceutical industry and for those in academia with an eye for biocatalysis, Applied Biocatalysis: The Chemist’s Enzyme Toolkit will also benefit academic groups in chemistry and related sciences that are using enzymes for synthetic purposes, as well as those working in the area of enzymology and molecular biology.

Book Quinazolinone and Quinazoline Derivatives

Download or read book Quinazolinone and Quinazoline Derivatives written by Ali Gamal Al-kaf and published by BoD – Books on Demand. This book was released on 2020-05-06 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the problems with modern public health is target searching for new highly effective medicinal preparations. Among those medicinal preparations are the natural and synthetic origins of quinazolinone-4 derivatives. Quinazolinone derivatives are reported to be physiologically and pharmacologically active. They also exhibit a wide range of activities such as anticonvulsant, antiinflammatory, antifungal, antimalarial, and sedative properties. Some of these compounds are identified as drugs used as diuretics, vasodilators, and antihypertensive agents. Moreover, sulfonamide derivatives have been widely used as bacteriostatic agents. Prompted by the above-mentioned facts and in conjunction with our ongoing program on the utility of readily obtainable starting material for the synthesis of heterocyclic systems of biological interest, we have decided to synthesize a series of quinazolinone derivatives having sulfonamide moiety with a potentially wide spectrum of biological responses.

Book Drugs for the Geriatric Patient

Download or read book Drugs for the Geriatric Patient written by Ronald I. Shorr and published by Saunders. This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This user-friendly, comprehensive drug reference - available in print and electronically for handheld, point-of-care usage -provides clinical information on more than 1000 drugs and their use in geriatric patients. In addition to dosage information and clinical indications, this reference also addresses the challenging issues of drug-drug and drug-disease interactions, polypharmacy, toxicity, compromised renal and hepatic function, withdrawal events, and more. Useful summary sections provide 1at a glance' conclusions, recommendations and clinical pearls. Quarterly updates to the handheld version ensure up-to-date access to the latest drug information and indications in the geriatric patient. Get comprehensive guidance on all the drugs you could conceivably encounter in treating the geriatric patient. Better serve your geriatric patients with dosage and usage guidelines developed specifically for them. Stay on top of all the latest drug information, including dosage updates and new drugs being released with frequent updates to the PDA version. Find information quickly using the practical, clinically-focused, full-color format.

Book Poly ADP Ribosyl ation

    Book Details:
  • Author : Alexander Bürkle
  • Publisher : Springer Science & Business Media
  • Release : 2008-01-11
  • ISBN : 0387360050
  • Pages : 260 pages

Download or read book Poly ADP Ribosyl ation written by Alexander Bürkle and published by Springer Science & Business Media. This book was released on 2008-01-11 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive, up-to-date reference on this post-translational modification of proteins, which is intimately linked with DNA repair, maintenance of genomic stability, transcriptional regulation, cell death and a variety of other cellular phenomena as well as with a variety of pathophysiological conditions, including ischemia-reperfusion damage, Parkinson’s disease, Type I diabetes mellitus, hemorrhagic and septic shock and other inflammatory conditions. Richly illustrated, it offers 19 chapters written by international experts.

Book Side Reactions in Organic Synthesis

Download or read book Side Reactions in Organic Synthesis written by Florencio Zaragoza Dörwald and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds. This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia. Contents: 1 Organic Synthesis: General Remarks 2 Stereoelectronic Effects and Reactivity 3 The Stability of Organic Compounds 4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles 5 The Alkylation of Carbanions 6 The Alkylation of Heteroatoms 7 The Acylation of Heteroatoms 8 Palladium-Catalyzed C-C Bond Formation 9 Cyclizations 10 Monofunctionalization of Symmetric Difunctional Substrates

Book Quinoxalines

    Book Details:
  • Author : Vakhid A. Mamedov
  • Publisher : Springer
  • Release : 2016-04-26
  • ISBN : 3319297732
  • Pages : 451 pages

Download or read book Quinoxalines written by Vakhid A. Mamedov and published by Springer. This book was released on 2016-04-26 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the fundamental aspects of quinoxaline chemistry: synthesis, reactions, mechanisms, structure, properties, and uses. The first four chapters present a survey of the developments in quinoxaline chemistry since the publication of the monograph on “Condensed Pyrazines” by Cheeseman and Cookson in 1979. These chapters give comprehensive coverage of all the methods of the synthesis of quinoxalines and the important quinoxaline-containing ring systems such as thiazolo[3,4-a]-, pyrrolo[1,2-a]-, and imidazo[1,5-a]quinoxalines. Chapter five describes many new methods for the construction of quinoxaline macrocycles, which are important in applications such as optical devices and materials. The final chapter reviews all previously known rearrangements of heterocyclic systems that lead to benzimidazole derivatives. Mamedov critically analyses these transformations to reveal a novel acid-catalyzed rearrangement of quinoxalinones giving 2-heteroarylbenzimidazoles and 1-heteroarylbenzimidazolones in the presence of nucleophilic reactants (MAMEDOV Heterocycle Rearrangement). This book is of interest to researchers in the fields of heterocyclic and synthetic organic chemistry.

Book Microwave Assisted Organic Synthesis

Download or read book Microwave Assisted Organic Synthesis written by Jason Tierney and published by John Wiley & Sons. This book was released on 2009-02-12 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first reports on the application of microwaves in organicsynthesis date back to 1986, but it was not until the recentintroduction of specifically designed and constructed equipment,which countered the safety and reproducibility concerns, thatsynthetic application of microwaves has become established as alaboratory technique. Microwave assisted synthesis is now beingadopted in many industrial and academic laboratories to takeadvantage of the novel chemistry that can be carried out using avariety of organic reaction types. This book demonstrates the underlying principles of microwavedielectric heating and, by reference to a range of organic reactiontypes, it's effective use in synthetic organic chemistry. Toillustrate the impact microwave assisted organic synthesis can haveon chemical research, case studies drawn mainly from thepharmaceutical industry are presented.