Download or read book Dendrimers in Medicine written by Barbara Klajnert and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dendrimer is a common name of polymers which are characterised by a specific structure, although their chemical composition can be very different. Dendrimers display several characteristics which distinguish them from linear polymers. All dendrimers are synthesised by attaching branched monomers to the central core molecule. Monomers are attached layer by layer. As a result of such a synthesis, dendrimers posses plenty of terminal, reactive groups on their surface and empty internal cavities. Both of these features can be utilised. Soon after the first synthesis in mid-1980's, dendrimers have become interesting and promising molecules for pharmaceutical and technical aims. The last years brought many new facts about dendrimers impact on biological systems. Both, general toxic studies, as well as detailed research devoted to particular cellular compounds, as DNA or lipid bilayer, were carried out. New types of dendrimers were synthesised and new applications appeared.
Download or read book Dendrimer Based Nanotherapeutics written by Prashant Kesharwani and published by Academic Press. This book was released on 2021-04-14 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields. Discusses various routes such as oral, pulmonary, transdermal, delivery and local administration of dendrimer delivery of bioactive Explores a wide range of applications of dendrimer-based drug delivery using the latest advancements in nanomedicine Provides the most recent research on dendrimers as well as context and background, providing a useful resource for all levels of researcher
Download or read book Dendrimers for Drug Delivery written by Anil K. Sharma and published by CRC Press. This book was released on 2018-07-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals.
Download or read book Dendrimers in Medical Science written by Zahoor Ahmad Parry and published by CRC Press. This book was released on 2017-05-25 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable new book offers a new perspective on dendrimers that bridges the gap between basic research and applied nanomedicine. It explores the ultimate effectiveness of dendrimers in theranostics, a promising field that combines therapeutics and diagnostics into single multifunctional formulations used to affect therapy or treatment of a disease state. The authors examine the potential uses of dendrimers, which have proven their capabilities in local/systemic drug delivery, physical stabilization of the drug, solubility enhancement of the poorly soluble drugs, and gene delivery.
Download or read book Dendrimers in Medicine and Biotechnology written by U Boas and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimers are a new class of macromolecule increasingly used in the fields of synthetic organic chemistry, biology, medicine and biotechnology. Dendrimers in Medicine and Biotechnology: New Molecular Tools looks at this exciting and rapidly growing area of science. Using an interdisciplinary approach with particular emphasis on biological applications, the book discusses the relationship between the dendrimer molecular motif and its biological properties. A general introduction to the subject of dendrimers, including definitions of terms and symbols, is provided. Subsequent sections discuss topics including dendrimers in biological systems, dendrimers as drug delivery devices, dendrimers in diagnostics and dendrimer drugs. Throughout the book examples from current research are also provided. This book will appeal to a wide range of scientists, including non specialists who require an introduction to dendrimers, as well as those wishing to know more about the application of dendrimers in the field of biology and medicine.
Download or read book Dendrimers in Nanomedicine written by Neelesh Kumar Mehra and published by CRC Press. This book was released on 2021-03-24 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimers, hyperbranched macromolecules, emerged just few decades ago but show promising potential as drug delivery nanocarriers, theranostic agents and gene vectors; in the pharmaceutical research and innovation area as well as in other healthcare applications. Although tremendous advancements have been made in dendrimer chemistry and their applications since their emergence, the synthesis, development and design of pure and safe dendrimer-based products have been a major challenge in this area. This book, edited by well-known researchers in the area of nanomaterials and drug-based drug delivery applications, exhaustively covers the nanotechnological aspects, concepts, properties, characterisation, application, biofate and regulatory aspects of dendrimers. It includes sixteen vivid chapters by renowned formulators, researchers and academicians from all over the world, highlighting their specialised areas of interest in the fields of chemistry, biology, pharmacy and nanomedicine. Features: • Highlights dendrimers’ advancements in nanomedicine in the development of safe healthcare and biotechnological products • Covers physicochemical aspects, biofate, drug delivery aspects and gene therapy using dendrimers • Covers biomedical application of dendrimers in the field of biological sciences • Gives examples of dendrimer–guest interaction chemistry Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives provides the comprehensive overview of the latest research efforts in designing, optimising, development and scale-up of dendrimer-mediated delivery systems. It analyses the key challenges of synthesis, design, molecular modelling, fundamental concepts, drug delivery aspects, analytical tools and biological fate as well as regulatory consideration to the practical use of dendrimer application. Dr. Neelesh Kumar Mehra Assistant Professor of Pharmaceutics in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He has authored more than sixty peer-reviewed publications in highly reputed international journals, as well as book chapters and contributions on two patents. Dr. Mehra has 11 years of rich research and teaching experience in the formulation and development of complex, innovative biopharmaceutical products including micro- and nanotechnologies for regulated markets. Dr. Keerti Jain Assistant Professor of Pharmaceutics in the Department of Pharmaceutics, NIPER, Raebareli, India. For more than 10 years, she has been actively engaged in formulation and development of nanomedicines. Dr. Jain has supervised masters and doctoral pharmaceutics students in their research works which have been published in high quality, good impact factor journals. She has also authored more than 60 international manuscripts in peer reviewed high impact journals. In 2019, she was awarded the prestigious ICMR-Amir Shakuntala Award.
Download or read book Dendrimers in Biomedical Applications written by Barbara Klajnert and published by Royal Society of Chemistry. This book was released on 2013 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide comprehensive coverage of dendrimer applications and clear indications for future research. It will appeal to chemists, biologists and materials scientists, working in both academia and industry.
Download or read book Dendrimers in Nanomedicine written by Neelesh Kumar Mehra and published by CRC Press. This book was released on 2021-03-22 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers dendrimer advance and future opportunity in nanomedicine with safety and efficacy in development of products Presents overview of recent progress in the field, its advances and bottlenecks, will help researchers to get a general insight of dendrimers applications Provides comprehensive overview of latest research efforts in designing, optimizing, development, scale up of dendrimers mediated delivery systems
Download or read book Dendrimers written by Anne-Marie Caminade and published by John Wiley & Sons. This book was released on 2011-08-31 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will be mainly focussed on the properties and uses of dendrimers and dendrons. The aim of this book is to be the reference book about dendrimers applications. It will not describe all details, but it will give the reader a unique overview of what has currently been done with dendrimers, with numerous references and illustrations. It will be divided in four main parts: Part 1) Generalities, syntheses, characterizations and properties; Part 2) Applications in catalysis; Part 3) Applications for the elaboration or modification of materials; and Part 4) Applications in biology/medicine. The role of the nanometric size and the multiple functions of dendrimers on the properties will be emphasized.
Download or read book Dendrimer Based Nanomedicine written by Istvan Majoros and published by Pan Stanford Publishing. This book was released on 2008-05-31 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining free-shaped synthetic macromolecules, this guide reveals how dendrimers are used in a variety of scientific applications as a safer, more precise, and more effective way to practice medicine. This book compiles and details cutting-edge research in science and medicine from the interdisciplinary team of the Michigan Nanotechnology Institute for Medicine and Biological Sciences, who are currently revolutionizing drug delivery techniques through the development of engineered nanodevices.
Download or read book Dendrimers in Biomedical Applications written by Barbara Klajnert and published by Royal Society of Chemistry. This book was released on 2013-05-31 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimers are important molecules that are currently undergoing investigation for use in a variety of different biomedical applications. This book explores the use of dendrimers for a variety of potential functions, including antiamyloidogenic agents, drug delivery systems, nucleic acid and RNA delivery vectors and to produce hybrid fibre platforms for nantechnology. Following the work of COST action TD0802, the main objective of which is to improve existing therapies and find new drugs based on dendrimers, the book will provide comprehensive coverage of dendrimer applications. Coverage includes modelling and molecular dynamic studies of dendrimers and dendrons, anionic dendrimer polymers, cationic carbosilane dendrimers and self-assembled multivalent dendrimers. Providing clear indications for future research and applications, this text will appeal to chemists, biologists and materials scientists, working in both academia and industry.
Download or read book Nanotechnology Based Approaches for Targeting and Delivery of Drugs and Genes written by Vijay Mishra and published by Academic Press. This book was released on 2017-05-23 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more
Download or read book Soft Nanoparticles for Biomedical Applications written by José Callejas-Fernández and published by Royal Society of Chemistry. This book was released on 2014-06-18 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles are attractive for many biomedical applications such as imaging, therapeutics and diagnostics. This new book looks at different soft nanoparticles and their current and potential uses in medicine and health including magnetoliposomes, micro/nanogels, polymeric micelles, DNA particles, dendrimers and bicelles. Each chapter provides a description of the synthesis of the particles and focus on the techniques used to characterize the size, shape, surface charge, internal structure, and surface microstructure of the nanoparticles together with modeling and simulation methods. By giving a strong physical-chemical approach to the topic, readers will gain a good background into the subject and an overview of recent developments. The multidisciplinary point of view makes the book suitable for postgraduate students and researchers in physics, chemistry, and biology interested in soft matter and its uses.
Download or read book Nanostructures for Oral Medicine written by Ecaterina Andronescu and published by Elsevier. This book was released on 2017-04-11 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field. Outlines the major uses of nanostructured materials for oral medicine, including the properties of each material discussed and how it should best be applied Explores how nanostructured materials enable the creation of more effective drug delivery systems in oral medicine Discusses how novel uses of nanostructured materials may be applied in oral medicine to create more effective devices
Download or read book Dendrimers in Medical Science written by Zahoor Ahmad Parry and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pharmaceutical Applications of Dendrimers written by Abhay Singh Chauhan and published by Elsevier. This book was released on 2019-11-15 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer. This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery. Explores the role of dendrimers in the design of dendritic nanoplatforms for targeted drug and gene delivery systems Discusses the potential of dendrimers in preformulation and formulation development Addresses both clinical and regulatory challenges in the development of dendrimer-based formulations
Download or read book Biopolymer Based Composites written by Sougata Jana and published by Woodhead Publishing. This book was released on 2017-06-15 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopolymer-Based Composites: Drug Delivery and Biomedical Applications presents a comprehensive review on recent developments in biopolymer-based composites and their use in drug delivery and biomedical applications. The information contained in this book is critical for the more efficient use of composites, as detailed up-to-date information is a pre-requirement. The information provided brings cutting-edge developments to the attention of young investigators to encourage further advances in the field of bio-composite research. Currently, biopolymers are being investigated for the design of various drug delivery and biomedical devices due to their non-toxic, biodegradable and biocompatible nature. Mostly, biopolymer-based solid orals, gels, hydrogel beads, and transdermal matrices have been designed in order to control drug/protein release in simulated bio-fluids. Presents the most updated information in the field of pharmaceutical and biological sciences Contains color figures and illustrations to help users understand key topics Useful guide for young researchers working towards new innovations Includes chapters covered by eminent scientists in the field
