Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Download or read book DNA Replication Recombination and Repair written by Fumio Hanaoka and published by Springer. This book was released on 2016-01-22 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1–3), DNA Replication; Part 2 (Chapters 4–6), DNA Recombination; Part 3 (Chapters 7–9), DNA Repair; Part 4 (Chapters 10–13), Genome Instability and Mutagenesis; Part 5 (Chapters 14–15), Chromosome Dynamics and Functions; Part 6 (Chapters 16–18), Cell Cycle and Checkpoints; Part 7 (Chapters 19–21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable.

Download or read book Beyond Repair written by Lois Peterson and published by Orca Book Publishers. This book was released on 2011-04-01 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key Selling Points New, enhanced features (dyslexia-friendly font, cream paper, larger trim size) to increase reading accessibility for dyslexic and other striving readers.

Download or read book Repair Brokenness Breakthrough written by Francisco Martínez and published by Berghahn Books. This book was released on 2019-09-01 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring some of the ways in which repair practices and perceptions of brokenness vary culturally, Repair, Brokenness, Breakthrough argues that repair is both a process and also a consequence which is sought out—an attempt to extend the life of things as well as an answer to failures, gaps, wrongdoings, and leftovers. This volume develops an open-ended combination of empirical and theoretical questions including: What does it mean to claim that something is broken? At what point is something broken repairable? What are the social relationships that take place around repair? And how much tolerance for failure do our societies have?

Download or read book Estimation of the Time Since Death written by Burkhard Madea and published by CRC Press. This book was released on 2015-09-08 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Estimation of the Time Since Death remains the foremost authoritative book on scientifically calculating the estimated time of death postmortem. Building on the success of previous editions which covered the early postmortem period, this new edition also covers the later postmortem period including putrefactive changes, entomology, and postmortem r

Download or read book RNA Damage and Repair written by Ioly Kotta-Loizou and published by Springer Nature. This book was released on 2021-07-04 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ribonucleic acid (RNA) is a macromolecule that plays a central role in cell physiology: RNA molecules act as intermediates between the deoxyribonucleic acid (DNA), where genetic information is stored, and proteins, which perform the necessary functions within the cell. Traditionally, the structural and functional properties of RNA are closely linked to gene expression. However, RNA-based enzymes, called ribozymes, are also involved in catalysis and small RNAs regulate key cellular processes, such as cell growth, division, differentiation, aging and death. RNA is a sensitive macromolecule that can be easily damaged by environmental conditions (ultraviolet radiation, oxidative stress) and biological factors (ribonucleases, ribotoxins, CRISPR-Cas systems). Therefore, cells have developed mechanisms to protect and/or repair RNA molecules. This book presents an overview of the biology of RNA damage, protection and repair in prokaryotes and eukaryotes. Individual chapters cover the expression regulation, enzymology and physiological role of such systems, and link them to important human diseases such as cancer and degenerative diseases.

Download or read book This Republic of Suffering written by Drew Gilpin Faust and published by Vintage. This book was released on 2009-01-06 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BESTSELLER • NATIONAL BOOK AWARD FINALIST • An "extraordinary ... profoundly moving" history (The New York Times Book Review) of the American Civil War that reveals the ways that death on such a scale changed not only individual lives but the life of the nation. An estiated 750,000 soldiers lost their lives in the American Civil War. An equivalent proportion of today's population would be seven and a half million. In This Republic of Suffering, Drew Gilpin Faust describes how the survivors managed on a practical level and how a deeply religious culture struggled to reconcile the unprecedented carnage with its belief in a benevolent God. Throughout, the voices of soldiers and their families, of statesmen, generals, preachers, poets, surgeons, nurses, northerners and southerners come together to give us a vivid understanding of the Civil War's most fundamental and widely shared reality. With a new introduction by the author, and a new foreword by Mike Mullen, 17th Chairman of the Joint Chiefs of Staff.

Download or read book Mechanisms of Cell Death written by Zahra Zakeri and published by . This book was released on 1999 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains papers from a July 1998 conference held at the Queens College Campus of the City University of New York. Papers are arranged in sections on mechanisms and general considerations, programmed (developmental) cell death, and cell death and pathological and clinical situations. Specific topics

Download or read book Necrotic Cell Death written by Han-Ming Shen and published by Springer Science & Business Media. This book was released on 2014-03-29 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. ​In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Download or read book Death Traps written by Belton Y. Cooper and published by Presidio Press. This book was released on 2007-12-18 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: “An important contribution to the history of World War II . . . I have never before been able to learn so much about maintenance methods of an armored division, with precise details that underline the importance of the work, along with descriptions of how the job was done.”—Russell F. Weigley, author of Eisenhower’s Lieutenants “Cooper saw more of the war than most junior officers, and he writes about it better than almost anyone. . . . His stories are vivid, enlightening, full of life—and of pain, sorrow, horror, and triumph.”—Stephen E. Ambrose, from his Foreword “In a down-to-earth style, Death Traps tells the compelling story of one man’s assignment to the famous 3rd Armored Division that spearheaded the American advance from Normandy into Germany. Cooper served as an ordnance officer with the forward elements and was responsible for coordinating the recovery and repair of damaged American tanks. This was a dangerous job that often required him to travel alone through enemy territory, and the author recalls his service with pride, downplaying his role in the vast effort that kept the American forces well equipped and supplied. . . . [Readers] will be left with an indelible impression of the importance of the support troops and how dependent combat forces were on them.”—Library Journal “As an alumnus of the 3rd, I eagerly awaited this book’s coming out since I heard of its release . . . and the wait and the book have both been worth it. . . . Cooper is a very polished writer, and the book is very readable. But there is a certain quality of ‘you are there’ many other memoirs do not seem to have. . . . Nothing in recent times—ridgerunning in Korea, firebases in Vietnam, or even the one hundred hours of Desert Storm—pressed the ingenuity and resolve of American troops . . . like WWII. This book lays it out better than any other recent effort, and should be part of the library of any contemporary warrior.”—Stephen Sewell, Armor Magazine “Cooper’s writing and recall of harrowing events is superb and engrossing. Highly recommended.”—Robert A. Lynn, The Stars and Stripes “This detailed story will become a classic of WWII history and required reading for anyone interested in armored warfare.”—Publishers Weekly (starred review) “[Death Traps] fills a critical gap in WWII literature. . . . It’s a truly unique and valuable work.”—G.I. Journal

Download or read book Model Rules of Professional Conduct written by American Bar Association. House of Delegates and published by American Bar Association. This book was released on 2007 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.

Download or read book Repair written by C. K. Williams and published by Farrar, Straus and Giroux. This book was released on 2014-09-09 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eighth book--and the most various yet--by a major American poet. With his two previous books, a generous Selected Poems and The Vigil, C. K. Williams received great acclaim, including the PEN/Voelcker Award and the prestigious Berlin Prize. Repair represents an extraordinary outpouring of nearly fifty new poems. His subjects, again, are love, death, secrets among intimates, the waywardness of thought, and the violence and metaphoric power of the natural world. A long poem about the sixties, "King," broods over the mixed motives and misunderstandings of the period; the final poem defines, and in its way celebrates, the "invisible mending" of time and attentiveness to the thing itself. Here is a poet in full maturity, his mastery transforming everything he touches. Repair is a 1999 National Book Award Finalist for Poetry and the winner of the 2000 Pulitzer Prize for Poetry.

Download or read book DNA Repair and Mutagenesis written by Errol C. Friedberg and published by American Society for Microbiology Press. This book was released on 2005-11-22 with total page 2587 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.

Download or read book Plant Cell Death Processes written by Larry D. Nooden and published by Elsevier. This book was released on 2003-12-09 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Programmed cell death is a common pattern of growth and development in both animals and plants. However, programmed cell death and related processes are not as generally recognized as central to plant growth. This is changing fast and is becoming more of a focus of intensive research. This edited work will bring under one cover recent reviews of programmed cell death, apoptosis and senescence.Summaries of the myriad aspects of cell death in plantsDiscussion of the broadest implications of these disparite resultsA unification of fields where there has been no cross talkEnables easy entry into diverse but related lines of research

Download or read book Repairing the World written by Linda Epstein and published by Simon and Schuster. This book was released on 2023-07-04 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: A young girl grapples with her grief over a tragic loss with the help of a new perspective from Hebrew school and supportive new friends in this heartfelt and “accessible” (Kirkus Reviews) middle grade novel about learning to look forward. Twelve-year-old Daisy and Ruby are totally inseparable. They’ve grown up together, and Daisy has always counted on having Ruby there to pave the way, encourage her to try new things, and to see the magic in the world. Then Ruby is killed in a tragic accident while on vacation, and Daisy’s life is shattered. Now Daisy finds herself having to face the big things in her life—like starting middle school and becoming a big sister—without her best friend. It’s hard when you feel sad all the time. But thanks to new friends, new insights, and supportive family members, Daisy is able to see what life after Ruby can look like. And as she reaches beyond that to help repair the world around her, she is reminded that friendship is eternal, and that magic can be found in the presence of anyone who chooses to embrace it.